QSI / Quantum-Si incorporated - Depositi SEC, Relazione annuale, dichiarazione di delega

Quantum-Si incorporated
US ˙ NasdaqGM ˙ US74765K1051

Statistiche di base
CIK 1816431
SEC Filings
All companies that sell securities in the United States must register with the Securities and Exchange Commission (SEC) and file reports on a regular basis. These reports include company annual reports (10K, 10Q), news updates (8K), investor presentations (found in 8Ks), insider trades (form 4), ownership reports (13D, and 13G), and reports related to the specific securities sold, such as registration statements and prospectus. This page shows recent SEC filings related to Quantum-Si incorporated
SEC Filings (Chronological Order)
Questa pagina fornisce un elenco completo e cronologico dei depositi SEC, esclusi i documenti di proprietà che forniamo altrove.
May 22, 2026 SD

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM SD Specialized Disclosure Report QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM SD Specialized Disclosure Report QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incorporation or organization) (Commission File Number) (I.R.S. Employer Identification No.) 29 Business Park Drive, Branford, Connecticut 06405 (Ad

May 15, 2026 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 15, 2026 QUANTUM-SI INCORPORA

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 15, 2026 QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incorporation) (Commission Fi

May 7, 2026 EX-99.1

Quantum-Si Reports First Quarter 2026 Financial Results and Highlights ProteusTM Development Milestones Successful sequencing on integrated Proteus instruments and continued progress toward amino acid coverage and overall launch capabilities

Exhibit 99.1 Quantum-Si Reports First Quarter 2026 Financial Results and Highlights ProteusTM Development Milestones Successful sequencing on integrated Proteus instruments and continued progress toward amino acid coverage and overall launch capabilities BRANFORD, Conn. - (BUSINESS WIRE) - May 7, 2026 - Quantum-Si Incorporated (Nasdaq: QSI) (“Quantum-Si,” “QSI” or the “Company”), a proteomics tech

May 7, 2026 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2026 or o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-39486 QUANTUM-S

May 7, 2026 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 7, 2026 QUANTUM-SI INCORPORAT

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 7, 2026 QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incorporation) (Commission Fil

May 7, 2026 EX-99.2

Use of Non-GAAP Financial Measures

Exhibit 99.2 Use of Non-GAAP Financial Measures In addition to financial results calculated in accordance with U.S. generally accepted accounting principles (“GAAP”), information containing non-GAAP financial measures for Quantum-Si Incorporated (the “Company”) was disclosed in the Company’s press release (the “Press Release”) dated May 7, 2026 announcing results for the three months ended March 3

April 1, 2026 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant  o Check the appropriate box: o Preliminary Proxy Statement o Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) o Definitive Proxy Stat

April 1, 2026 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

TABLE OF CONTENTS UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant  o Check the appropriate box: o Preliminary Proxy Statement o Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) x Def

April 1, 2026 ARS

ARS

ANNUAL REPORT 2025 www.quantum-si.com [THIS PAGE INTENTIONALLY LEFT BLANK] UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K x ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2025 or o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition

March 3, 2026 EX-10.18

AMENDED AND RESTATED QUANTUM-SI INCORPORATED EXECUTIVE SEVERANCE PLAN PLAN DOCUMENT AND SUMMARY PLAN DESCRIPTION Effective as of November 1, 2024 1. Establishment of Plan. Quantum-Si Incorporated (the “Company”), hereby establishes an unfunded severa

quantum-siseveranceplan AMENDED AND RESTATED QUANTUM-SI INCORPORATED EXECUTIVE SEVERANCE PLAN PLAN DOCUMENT AND SUMMARY PLAN DESCRIPTION Effective as of November 1, 2024 1.

March 3, 2026 EX-19.1

QUANTUM- SI INCORPORATED INSIDER TRADING POLICY (Effective October 2025) TABLE OF CONTENTS Page I. The Need for an Insider Trading Policy ............................................................ 2 II. What is Material Non-Public Information? ....

quantum-sixinsidertradin QUANTUM- SI INCORPORATED INSIDER TRADING POLICY (Effective October 2025) TABLE OF CONTENTS Page I.

March 3, 2026 S-8

As filed with the Securities and Exchange Commission on March 3, 2026

S-8 As filed with the Securities and Exchange Commission on March 3, 2026 Registration No.

March 3, 2026 EX-99.2

Use of Non-GAAP Financial Measures

Exhibit 99.2 Use of Non-GAAP Financial Measures In addition to financial results calculated in accordance with U.S. generally accepted accounting principles (“GAAP”), information containing non-GAAP financial measures for Quantum-Si Incorporated (the “Company”) was disclosed in the Company’s press release (the “Press Release”) dated March 3, 2026 announcing results for the fourth quarter and full

March 3, 2026 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K x ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2025 or o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period fromto Commission File Number: 001-39486 QUANTUM-

March 3, 2026 EX-FILING FEES

Table 1: Newly Registered Securities

Calculation of Filing Fee Tables S-8 Quantum-Si Inc Table 1: Newly Registered Securities Security Type Security Class Title Fee Calculation Rule Amount Registered Proposed Maximum Offering Price Per Unit Maximum Aggregate Offering Price Fee Rate Amount of Registration Fee 1 Equity Class A common stock, par value $0.

March 3, 2026 EX-99.1

Quantum-Si Reports Fourth Quarter and Full Year 2025 Financial Results Releases List Price of ProteusTM Platform Reiterates Proteus Development Program On Track for Year End 2026 Launch

Exhibit 99.1 Quantum-Si Reports Fourth Quarter and Full Year 2025 Financial Results Releases List Price of ProteusTM Platform Reiterates Proteus Development Program On Track for Year End 2026 Launch BRANFORD, Conn. - (BUSINESS WIRE) - March 3, 2026 - Quantum-Si Incorporated (Nasdaq: QSI) (“Quantum-Si,” “QSI” or the “Company”), a proteomics technology company redefining protein analysis through sin

March 3, 2026 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 3, 2026 QUANTUM-SI INCORPOR

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 3, 2026 QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incorporation) (Commission F

December 29, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 29, 2025 QUANTUM-SI INCO

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 29, 2025 QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incorporation) (Commissi

December 29, 2025 EX-99.1

1 Corporate Presentation Exhibit 99.1 2 Disclaimer and Other Information Forward-looking Statements This presentation includes “forward-looking statements” within the meaning of the “safe harbor” provisions of the United States Private Securities Lit

corporatepresentation122 1 Corporate Presentation Exhibit 99.1 2 Disclaimer and Other Information Forward-looking Statements This presentation includes “forward-looking statements” within the meaning of the “safe harbor” provisions of the United States Private Securities Litigation Reform Act of 1995. The actual results of the Company may differ from its expectations, estimates, and projections an

November 20, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 19, 2025 QUANTUM-SI INCO

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 19, 2025 QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incorporation) (Commissi

November 20, 2025 EX-99.1

1 Quantum Si Investor & Analyst Day November 19, 2025 2 Investor Day Agenda 10:00–10:10 AMTackling the Complexity of the ProteomeJeff Hawkins, CEO 10:10–10:40 AM Proteus Program Update and Long-term Technology Roadmap Todd Rearick, CTO 10:40–11:05 AM

investoranalystday11-19x 1 Quantum Si Investor & Analyst Day November 19, 2025 2 Investor Day Agenda 10:00–10:10 AMTackling the Complexity of the ProteomeJeff Hawkins, CEO 10:10–10:40 AM Proteus Program Update and Long-term Technology Roadmap Todd Rearick, CTO 10:40–11:05 AMThe Path to Detecting All 20 Amino AcidsJohn Vieceli, CPO 11:05–11:25 AMPost-translational Modification Analysis Solutions Br

November 5, 2025 EX-10.5

Exhibit 10.5 October 31, 2025 Todd Bennett Re: Separation Agreement Dear Todd: The purpose of this letter agreement (this “Agreement”) is to confirm the end of your employment with Quantum-Si Incorporated (the “Company”) as of November 7, 2025 (the “

bennettseparationagreeme Exhibit 10.5 October 31, 2025 Todd Bennett Re: Separation Agreement Dear Todd: The purpose of this letter agreement (this “Agreement”) is to confirm the end of your employment with Quantum-Si Incorporated (the “Company”) as of November 7, 2025 (the “Separation Date”), and to set forth the terms of your separation from Quantum-Si Incorporated (“Company”). Payment of the Sep

November 5, 2025 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2025 or o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-39486 QUANT

November 5, 2025 EX-99.2

Use of Non-GAAP Financial Measures

Exhibit 99.2 Use of Non-GAAP Financial Measures In addition to financial results calculated in accordance with U.S. generally accepted accounting principles (“GAAP”), information containing non-GAAP financial measures for Quantum-Si Incorporated (the “Company”) was disclosed in the Company’s press release (the “Press Release”) dated November 5, 2025 announcing results for the three and nine months

November 5, 2025 EX-99.1

Quantum-Si Reports Third Quarter 2025 Financial Results Announces Successful Sequencing on Prototype Proteus Unit, Development Program Remains

Exhibit 99.1 Quantum-Si Reports Third Quarter 2025 Financial Results Announces Successful Sequencing on Prototype Proteus Unit, Development Program Remains On-Track BRANFORD, Conn. - (BUSINESS WIRE) - November 5, 2025 - Quantum-Si Incorporated (Nasdaq: QSI) (“Quantum-Si,” “QSI” or the “Company”), a proteomics technology company redefining protein analysis through single-molecule detection, today a

November 5, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 5, 2025 QUANTUM-SI INCOR

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 5, 2025 QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incorporation) (Commissio

October 29, 2025 424B3

Up to $100,000,000 Class A Common Stock

TABLE OF CONTENTS Filed Pursuant to Rule 424(b)(3) Registration No. 333-290559 PROSPECTUS   Up to $100,000,000   Class A Common Stock We have entered into a Sales Agreement (the “Sales Agreement”) with Leerink Partners LLC (“Leerink Partners”) relating to our Class A common stock, par value $0.0001 per share (“Class A common stock”), offered by this prospectus. In accordance with the terms of the

October 9, 2025 S-3/A

As filed with the Securities and Exchange Commission on October 9, 2025

TABLE OF CONTENTS As filed with the Securities and Exchange Commission on October 9, 2025 Registration No.

September 29, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 26, 2025 QUANTUM-SI INC

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 26, 2025 QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incorporation) (Commiss

September 26, 2025 EX-10.1

Page 1 of 6 CERTAIN CONFIDENTIAL INFORMATION CONTAINED IN THIS DOCUMENT, MARKED BY [***], HAS BEEN OMITTED BECAUSE IT IS BOTH NOT MATERIAL AND IS THE TYPE THAT THE REGISTRANT CUSTOMARILY AND ACTUALLY TREATS AS PRIVATE OR CONFIDENTIAL. SETTLEMENT AND

mutualreleaseagreement Page 1 of 6 CERTAIN CONFIDENTIAL INFORMATION CONTAINED IN THIS DOCUMENT, MARKED BY [***], HAS BEEN OMITTED BECAUSE IT IS BOTH NOT MATERIAL AND IS THE TYPE THAT THE REGISTRANT CUSTOMARILY AND ACTUALLY TREATS AS PRIVATE OR CONFIDENTIAL.

September 26, 2025 EX-4.4

QUANTUM-SI INCORPORATED [ ] Trustee Dated as of [ ] Subordinated Debt Securities TABLE OF CONTENTS1

Exhibit 4.4 QUANTUM-SI INCORPORATED Issuer AND [ ] Trustee INDENTURE Dated as of [ ] Subordinated Debt Securities TABLE OF CONTENTS1 Page ARTICLE I DEFINITIONS 1 SECTION 1.01 Definitions of Terms 1 ARTICLE II ISSUE, DESCRIPTION, TERMS, EXECUTION, REGISTRATION AND EXCHANGE OF SECURITIES 4 SECTION 2.01 Designation and Terms of Securities 4 SECTION 2.02 Form of Securities and Trustee’s Certificate 5

September 26, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 23, 2025 QUANTUM-SI INC

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 23, 2025 QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incorporation) (Commiss

September 26, 2025 EX-4.3

QUANTUM-SI INCORPORATED [ ] Trustee Dated as of [ ] Senior Debt Securities TABLE OF CONTENTS1

Exhibit 4.3 QUANTUM-SI INCORPORATED Issuer AND [ ] Trustee INDENTURE Dated as of [ ] Senior Debt Securities TABLE OF CONTENTS1 Page ARTICLE I DEFINITIONS 1 SECTION 1.01 Definitions of Terms 1 ARTICLE II ISSUE, DESCRIPTION, TERMS, EXECUTION, REGISTRATION AND EXCHANGE OF SECURITIES 4 SECTION 2.01 Designation and Terms of Securities 4 SECTION 2.02 Form of Securities and Trustee’s Certificate 5 SECTIO

September 26, 2025 S-3

As filed with the Securities and Exchange Commission on September 26, 2025

TABLE OF CONTENTS As filed with the Securities and Exchange Commission on September 26, 2025 Registration No.

September 26, 2025 EX-1.2

QUANTUM-SI INCORPORATED Shares of Class A Common Stock ($0.0001 par value per share) SALES AGREEMENT

Exhibit 1.2 QUANTUM-SI INCORPORATED Shares of Class A Common Stock ($0.0001 par value per share) SALES AGREEMENT September 26, 2025 LEERINK PARTNERS LLC 1301 Avenue of the Americas, 5th Floor New York, New York 10019 Ladies and Gentlemen: Quantum-Si Incorporated, a Delaware corporation (the “Company”), confirms its agreement (this “Agreement”) with Leerink Partners LLC (the “Agent”), as follows: 1

September 26, 2025 EX-FILING FEES

Calculation of Filing Fee Tables Form S-3 (Form Type) Quantum-Si Incorporated (Exact Name of Registrant as Specified in Its Charter) Table 1: Newly Registered and Carry Forward Securities

Exhibit 107 Calculation of Filing Fee Tables Form S-3 (Form Type) Quantum-Si Incorporated (Exact Name of Registrant as Specified in Its Charter) Table 1: Newly Registered and Carry Forward Securities Security Type Security Class Title Fee Calculation or Carry Forward Rule Amount Registered Proposed Maximum Offering Price Per Unit Maximum Aggregate Offering Price Fee Rate  Amount of Registration Fee(1)(2) Carry Forward Form Type Carry Forward File Number Carry Forward Initial Effective Date Filing Fee Previously Paid in Connection with Unsold Securities to be Carried Forward Newly Registered Securities Fees to Be Paid Equity Class A common stock, $0.

August 8, 2025 EX-99.1

1 Corporate Presentation 2 Disclaimer and Other Information Forward-looking Statements This presentation includes "forward-looking statements" within the meaning of the "safe harbor" provisions of the United States Private Securities Litigation Refor

1 Corporate Presentation 2 Disclaimer and Other Information Forward-looking Statements This presentation includes "forward-looking statements" within the meaning of the "safe harbor" provisions of the United States Private Securities Litigation Reform Act of 1995.

August 8, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 8, 2025 QUANTUM-SI INCORPO

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 8, 2025 QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incorporation) (Commission

August 5, 2025 EX-99.2

Use of Non-GAAP Financial Measures

Exhibit 99.2 Use of Non-GAAP Financial Measures In addition to financial results calculated in accordance with U.S. generally accepted accounting principles (“GAAP”), information containing non-GAAP financial measures for Quantum-Si Incorporated (the “Company”) was disclosed in the Company’s press release (the “Press Release”) dated August 5, 2025 announcing results for the three and six months en

August 5, 2025 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2025 or o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-39486 QUANTUM-SI

August 5, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 5, 2025 QUANTUM-SI INCORPO

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 5, 2025 QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incorporation) (Commission

August 5, 2025 EX-99.1

Quantum-Si Reports Second Quarter 2025 Financial Results Announced On-Track ProteusTM Development Program Completes Capital Raise of $50 Million

Exhibit 99.1 Quantum-Si Reports Second Quarter 2025 Financial Results Announced On-Track ProteusTM Development Program Completes Capital Raise of $50 Million BRANFORD, Conn. - (BUSINESS WIRE) - August 5, 2025 - Quantum-Si Incorporated (Nasdaq: QSI) (“Quantum-Si,” “QSI” or the “Company”), a proteomics technology company redefining protein analysis through single-molecule detection, today announced

July 7, 2025 EX-4.1

PRE-FUNDED COMMON STOCK PURCHASE WARRANT QUANTUM-SI INCORPORATED

Exhibit 4.1 PRE-FUNDED COMMON STOCK PURCHASE WARRANT QUANTUM-SI INCORPORATED Warrant Shares: Issue Date: July [•], 2025 THIS PRE-FUNDED COMMON STOCK PURCHASE WARRANT (the “Warrant”) certifies that, for value received, or its assigns (the “Holder”) is entitled, upon the terms and subject to the limitations on exercise and the conditions hereinafter set forth, at any time on or after the date hereof

July 7, 2025 424B5

The date of this prospectus supplement is July 7, 2025.

Filed Pursuant to Rule 424(b)(5) Registration No. 333-273934 PROSPECTUS SUPPLEMENT (To Prospectus Supplement dated December 11, 2024 and Prospectus dated August 22, 2023)   This prospectus supplement supplements and amends certain information contained in the prospectus dated August 22, 2023 (the “Base Prospectus”), as supplemented by our prospectus supplement dated December 11, 2024 (the “Prospec

July 7, 2025 424B5

18,200,000 Shares of Class A Common Stock Pre-Funded Warrants to Purchase up to 11,740,119 Shares of Class A Common Stock Up to 11,740,119 Shares of Class A Common Stock Underlying the Pre- Funded Warrants

TABLE OF CONTENTS Filed Pursuant to Rule 424(b)(5) Registration No. 333-273934 PROSPECTUS SUPPLEMENT (To Prospectus Dated August 22, 2023)   18,200,000 Shares of Class A Common Stock   Pre-Funded Warrants to Purchase up to 11,740,119 Shares of Class A Common Stock   Up to 11,740,119 Shares of Class A Common Stock Underlying the Pre- Funded Warrants Pursuant to this prospectus supplement and the ac

July 7, 2025 8-K

Entry into a Material Definitive Agreement, Termination of a Material Definitive Agreement, Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 3, 2025 QUANTUM-SI INCORPORATED (Exact Name of Registrant as Specified in Charter) Delaware 001-39486 85-1388175 (State or Other Jurisdiction of Incorporation) (Commission File Number) (I.

July 7, 2025 EX-99.1

Quantum-Si Incorporated Announces Pricing of $50 Million Registered Direct Offering of Common Stock

Exhibit 99.1 Quantum-Si Incorporated Announces Pricing of $50 Million Registered Direct Offering of Common Stock BRANFORD, Conn., July 3, 2025-(BUSINESS WIRE)-Quantum-Si Incorporated (Nasdaq: QSI) (“Quantum-Si,” “QSI” or the “Company”), a proteomics technology company redefining protein analysis through single-molecule detection, today announced that it has entered into a securities purchase agree

July 7, 2025 EX-10.2

[The remainder of this page has been intentionally left blank.]

Exhibit 10.2 July 3, 2025 Quantum-SI Incorporated Attn: Jeffry Keyes, Chief Financial Officer 29 Business Park Drive Branford, Connecticut 06405 Dear Mr. Keyes: This letter (the “Agreement”) constitutes the agreement between A.G.P./Alliance Global Partners (the “Placement Agent”) and Quantum-SI Incorporated, a Delaware corporation (the “Company”), that the Placement Agent shall serve as the exclus

July 7, 2025 EX-10.1

SECURITIES PURCHASE AGREEMENT

Exhibit 10.1 SECURITIES PURCHASE AGREEMENT This Securities Purchase Agreement (this “Agreement”) is dated as of July 3, 2025, between Quantum-Si Incorporated, a Delaware corporation (the “Company”), and each purchaser identified on the signature pages hereto (each, including its successors and assigns, a “Purchaser” and collectively, the “Purchasers”). WHEREAS, subject to the terms and conditions

May 22, 2025 SD

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM SD Specialized Disclosure Report QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549 FORM SD Specialized Disclosure Report QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incorporation or organization) (Commission File Number) (I.R.S. Employer Identification No.) 29 Business Park Drive, Branford, Connecticut 06405 (Ad

May 22, 2025 EX-1.01

Exhibit No. 1.01 - Conflict Minerals Report

Exhibit 1.01 Section 1 – Conflict Minerals Disclosure Item 1.01 Conflict Minerals Disclosure and Report This Specialized Disclosure Form of Quantum-Si Incorporated (the “Company”) is being filed in accordance with Rule 13p-1 (the “Rule”) under the Securities Exchange Act of 1934, as amended, for the reporting period from January 1, 2024 to December 31, 2024 (the “Relevant Period”). The Rule impose

May 19, 2025 8-K

Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 16, 2025 QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incorporation) (Commission Fi

May 15, 2025 EX-99.2

Use of Non-GAAP Financial Measures

Exhibit 99.2 Use of Non-GAAP Financial Measures In addition to financial results calculated in accordance with U.S. generally accepted accounting principles (“GAAP”), information containing non-GAAP financial measures for Quantum-Si Incorporated (the “Company”) was disclosed in the Company’s press release (the “Press Release”) dated May 15, 2025 announcing results for the three months ended March

May 15, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 15, 2025 QUANTUM-SI INCORPORA

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 15, 2025 QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incorporation) (Commission Fi

May 15, 2025 EX-99.1

Quantum-Si Reports First Quarter 2025 Financial Results Launches and Delivers First Platinum® Pro Units Announces New Library Preparation Development Program

Exhibit 99.1 Quantum-Si Reports First Quarter 2025 Financial Results Launches and Delivers First Platinum® Pro Units Announces New Library Preparation Development Program BRANFORD, Conn. - (BUSINESS WIRE) - May 15, 2025 - Quantum-Si Incorporated (Nasdaq: QSI) (“Quantum-Si,” “QSI” or the “Company”), The Protein Sequencing Company™, today announced financial results for the first quarter ended March

May 15, 2025 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2025 or o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-39486 QUANTUM-S

April 10, 2025 EX-99.1

1 Corporate Presentation 2 Disclaimer and Other Information Forward-looking Statements This presentation includes "forward-looking statements" within the meaning of the "safe harbor" provisions of the United States Private Securities Litigation Refor

1 Corporate Presentation 2 Disclaimer and Other Information Forward-looking Statements This presentation includes "forward-looking statements" within the meaning of the "safe harbor" provisions of the United States Private Securities Litigation Reform Act of 1995.

April 10, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 10, 2025 QUANTUM-SI INCORPO

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 10, 2025 QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incorporation) (Commission

March 20, 2025 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant  o Check the appropriate box: o Preliminary Proxy Statement o Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) o Definitive Proxy Stat

March 20, 2025 ARS

ARS

ANNUAL REPORT 2024 www.quantum-si.com [THIS PAGE INTENTIONALLY LEFT BLANK] UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K  ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2024 or  TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition

March 20, 2025 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

TABLE OF CONTENTS UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant  o Check the appropriate box: o Preliminary Proxy Statement o Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) x Def

March 3, 2025 EX-99.2

Use of Non-GAAP Financial Measures

Exhibit 99.2 Use of Non-GAAP Financial Measures In addition to financial results calculated in accordance with U.S. generally accepted accounting principles (“GAAP”), information containing non-GAAP financial measures for Quantum-Si Incorporated (the “Company”) was disclosed in the Company’s press release (the “Press Release”) dated March 3, 2025 announcing results for the fourth quarter and full

March 3, 2025 EX-FILING FEES

Calculation of Filing Fee Tables Form S-8 (Form Type) Quantum-Si Incorporated (Exact Name of Registrant as Specified in its Charter) Table 1: Newly Registered Securities

Exhibit 107 Calculation of Filing Fee Tables Form S-8 (Form Type) Quantum-Si Incorporated (Exact Name of Registrant as Specified in its Charter) Table 1: Newly Registered Securities Security Type Security Class Title Fee Calculation Rule Amount Registered(1) Proposed Maximum Offering Price Per Unit Maximum Aggregate Offering Price Fee Rate Amount of Registration Fee Equity Class A common stock, par value $0.

March 3, 2025 S-8

As filed with the Securities and Exchange Commission on March 3, 2025

As filed with the Securities and Exchange Commission on March 3, 2025 Registration No.

March 3, 2025 EX-10.20

AMENDED AND RESTATED QUANTUM-SI INCORPORATED EXECUTIVE SEVERANCE PLAN PLAN DOCUMENT AND SUMMARY PLAN DESCRIPTION Effective as of November 1, 2024

Exhibit 10.20 AMENDED AND RESTATED QUANTUM-SI INCORPORATED EXECUTIVE SEVERANCE PLAN PLAN DOCUMENT AND SUMMARY PLAN DESCRIPTION Effective as of November 1, 2024 1.Establishment of Plan. Quantum-Si Incorporated (the “Company”), hereby establishes an unfunded severance benefits plan (this “Plan”) that is intended to be a welfare benefit plan within the meaning of Section 3(1) of ERISA. This Plan, ori

March 3, 2025 EX-99.1

Quantum-Si Reports Fourth Quarter and Full Year 2024 Financial Results Achieves First Quarterly Revenue Over $1 Million Completes Capital Raises of $86 Million

Exhibit 99.1 Quantum-Si Reports Fourth Quarter and Full Year 2024 Financial Results Achieves First Quarterly Revenue Over $1 Million Completes Capital Raises of $86 Million BRANFORD, Conn. - (BUSINESS WIRE) - March 3, 2025 - Quantum-Si Incorporated (Nasdaq: QSI) (“Quantum-Si,” “QSI” or the “Company”), The Protein Sequencing Company™, today announced financial results for the fourth quarter and ful

March 3, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 3, 2025 QUANTUM-SI INCORPOR

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 3, 2025 QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incorporation) (Commission F

March 3, 2025 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K x ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2024 or o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period fromto Commission File Number: 001-39486 QUANTUM-

March 3, 2025 EX-19.1

QUANTUM- SI INCORPORATED INSIDER TRADING POLICY (Effective February 2025) TABLE OF CONTENTS Page I. The Need for an Insider Trading Policy 2 II. What is Material Non-Public Information? 2 III. The Consequences of Insider Trading 4 IV. Our Policy 5 Ge

Exhibit 19.1 QUANTUM- SI INCORPORATED INSIDER TRADING POLICY (Effective February 2025) TABLE OF CONTENTS Page I. The Need for an Insider Trading Policy 2 II. What is Material Non-Public Information? 2 III. The Consequences of Insider Trading 4 IV. Our Policy 5 General Prohibition on Trading 5 Transactions by Family Members, Others in Your Household and Entities You Control 5 Other Companies’ Non-p

February 13, 2025 EX-99.1

Exhibit A

EX-99.1 2 ef20043545ex99-1.htm EXHIBIT A Exhibit A Pursuant to the instructions in Items 6 and 7 of Schedule 13G, the security being reported on by Nikko Asset Management Americas, Inc., as subsidiary to the parent holding companies listed below, are owned, or may be deemed to be beneficially owned, by its parent holding companies. 1) Sumitomo Mitsui Trust Group Inc. o A parent holding company or

January 6, 2025 EX-10.1

SECURITIES PURCHASE AGREEMENT

EXHIBIT 10.1 SECURITIES PURCHASE AGREEMENT This Securities Purchase Agreement (this “Agreement”) is dated as of January 3, 2025, between Quantum-Si Incorporated, a Delaware corporation (the “Company”), and each purchaser identified on the signature pages hereto (each, including its successors and assigns, a “Purchaser” and collectively, the “Purchasers”). WHEREAS, subject to the terms and conditio

January 6, 2025 424B5

15,625,000 Shares of Class A Common Stock

TABLE OF CONTENTS Filed Pursuant to Rule 424(b)(5) Registration No. 333-273934 PROSPECTUS SUPPLEMENT (To Prospectus Dated August 22, 2023)   15,625,000 Shares of Class A Common Stock Pursuant to this prospectus supplement and the accompanying prospectus, we are offering in a registered direct offering to certain purchasers 15,625,000 shares of our Class A common stock, par value $0.0001 per share

January 6, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 3, 2025 QUANTUM-SI INCORPOR

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 3, 2025 QUANTUM-SI INCORPORATED (Exact Name of Registrant as Specified in Charter) Delaware 001-39486 85-1388175 (State or Other Jurisdiction of Incorporation) (Commission File Number) (I.

January 6, 2025 EX-99.1

Quantum-Si Incorporated Announces Pricing of $50 Million Registered Direct Offering of Common Stock

Exhibit 99.1 Quantum-Si Incorporated Announces Pricing of $50 Million Registered Direct Offering of Common Stock BRANFORD, Conn., January 3, 2025-(BUSINESS WIRE)-Quantum-Si Incorporated (Nasdaq: QSI) (“Quantum-Si,” “QSI” or the “Company”), The Protein Sequencing Company™, today announced that it has entered into securities purchase agreements with certain institutional investors for the purchase a

January 6, 2025 EX-10.2

[The remainder of this page has been intentionally left blank.]

Exhibit 10.2 January 3, 2025 Quantum-SI Incorporated Attn: Jeffry Keyes, Chief Financial Officer 29 Business Park Drive Branford, Connecticut 06405 Dear Mr. Keyes: This letter (the “Agreement”) constitutes the agreement between A.G.P./Alliance Global Partners (the “Placement Agent”) and Quantum-SI Incorporated, a Delaware corporation (the “Company”), that the Placement Agent shall serve as the exc

December 11, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 11, 2024 QUANTUM-SI INCORP

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 11, 2024 QUANTUM-SI INCORPORATED (Exact Name of Registrant as Specified in Charter) Delaware 001-39486 85-1388175 (State or Other Jurisdiction of Incorporation) (Commission File Number) (I.

December 11, 2024 424B5

Up to $75,000,000 Class A Common Stock

TABLE OF CONTENTS Filed pursuant to Rule 424(b)(5) Registration No. 333-273934 PROSPECTUS SUPPLEMENT (To Prospectus Dated August 22, 2023)   Up to $75,000,000   Class A Common Stock We have entered into an Equity Distribution Agreement (the “Equity Distribution Agreement”) with Canaccord Genuity LLC (“Canaccord”) relating to our Class A common stock, par value $0.0001 per share (“Class A common st

December 11, 2024 EX-10.1

QUANTUM-SI INCORPORATED Class A Common Stock (par value $0.0001 per share) Having an Aggregate Offering Price of Up to $75,000,000 Equity Distribution Agreement

Exhibit 10.1 QUANTUM-SI INCORPORATED Class A Common Stock (par value $0.0001 per share) Having an Aggregate Offering Price of Up to $75,000,000 Equity Distribution Agreement December 11, 2024 Canaccord Genuity LLC 1 Post Office Square, Suite 3000 Boston, Massachusetts 02109 Ladies and Gentlemen: Quantum-Si Incorporated, a Delaware corporation (the “Company”) confirms its agreement (this “Agreement

December 9, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 4, 2024 QUANTUM-SI INCOR

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 4, 2024 QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incorporation) (Commissio

November 22, 2024 8-K

Costs Associated with Exit or Disposal Activities

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 21, 2024 QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incorporation) (Commissi

November 21, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 20, 2024 QUANTUM-SI INCO

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 20, 2024 QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incorporation) (Commissi

November 21, 2024 EX-99.1

Investor & Analyst Day November 20, 2024 Forward Looking Statements This presentation includes “forward-looking statements” within the meaning of the “safe harbor” provisions of the United States Private Securities Litigation Reform Act of 1995. The

Exhibit 99.1 Investor & Analyst Day November 20, 2024 Forward Looking Statements This presentation includes “forward-looking statements” within the meaning of the “safe harbor” provisions of the United States Private Securities Litigation Reform Act of 1995. The actual results of the Company may differ from its expectations, estimates, and projections and, consequently, you should not rely on thes

November 12, 2024 EX-10.2

August 22, 2024

Exhibit 10.2 August 22, 2024 TODD BENNETT Dear Todd: On behalf of Quantum-Si, I am pleased to offer you a position as Chief Commercial Officer beginning September 17, 2024. You will report to Jeff Hawkins. Your annualized compensation in this position will consist of an annual base salary of $425,000 paid in twice monthly pay periods, less required deductions. For calendar year 2024, you will be e

November 12, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 12, 2024 QUANTUM-SI INCO

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 12, 2024 QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incorporation) (Commissi

November 12, 2024 EX-99.1

Quantum-Si Reports Third Quarter 2024 Financial Results Sales Pipeline is Accelerating and New Kits Remain on Track for Q4 Launch

Exhibit 99.1 Quantum-Si Reports Third Quarter 2024 Financial Results Sales Pipeline is Accelerating and New Kits Remain on Track for Q4 Launch BRANFORD, Conn. - (BUSINESS WIRE) - November 12, 2024 - Quantum-Si Incorporated (Nasdaq: QSI) (“Quantum-Si,” “QSI” or the “Company”), The Protein Sequencing Company™, today announced financial results for the third quarter ended September 30, 2024. Press Re

November 12, 2024 EX-10.1

August 12, 2024

Exhibit 10.1 August 12, 2024 JOHN VIECELI Dear John: Congratulations. This letter confirms the terms of your employment in connection with your promotion to Chief Product Officer. We are pleased to inform you that your new annual base salary will be $395,000 to be paid twice per month, less required deductions. This is effective August 12, 2024. In addition, your new bonus target will be 50% prora

November 12, 2024 EX-10.3

QUANTUM-SI INCORPORATED 2023 INDUCEMENT EQUITY INCENTIVE PLAN (As Amended on August 23, 2024)

Exhibit 10.3 QUANTUM-SI INCORPORATED 2023 INDUCEMENT EQUITY INCENTIVE PLAN (As Amended on August 23, 2024) 1.DEFINITIONS. Unless otherwise specified or unless the context otherwise requires, the following terms, as used in this Quantum-Si Incorporated 2023 Inducement Equity Incentive Plan, have the following meanings: Administrator means the Board of Directors, unless it has delegated power to act

November 12, 2024 EX-10.3 1

QUANTUM-SI INCORPORATED Restricted Stock Unit Award Grant Notice Restricted Stock Unit Grant under the Company’s 2023 Inducement Equity Incentive Plan

Exhibit 10.3.1 QUANTUM-SI INCORPORATED Restricted Stock Unit Award Grant Notice Restricted Stock Unit Grant under the Company’s 2023 Inducement Equity Incentive Plan Name: Grant Number: Grant Date: Grant Type: Grant Shares: Vesting of Award: This Restricted Stock Unit Award shall vest as follows provided the Participant is an Employee of the Company or of an Affiliate on the applicable vesting dat

November 12, 2024 8-K/A

Notice of Delisting or Failure to Satisfy a Continued Listing Rule or Standard; Transfer of Listing

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K/A (Amendment No. 1) CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 4, 2024 QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incor

November 12, 2024 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2024 or o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-39486 QUANT

November 12, 2024 EX-99.2

Use of Non-GAAP Financial Measures

Exhibit 99.2 Use of Non-GAAP Financial Measures In addition to financial results calculated in accordance with U.S. generally accepted accounting principles (“GAAP”), information containing non-GAAP financial measures for Quantum-Si Incorporated (the “Company”) was disclosed in the Company’s press release (the “Press Release”) dated November 12, 2024 announcing results for the three and nine month

November 8, 2024 8-K

Notice of Delisting or Failure to Satisfy a Continued Listing Rule or Standard; Transfer of Listing

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 4, 2024 QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incorporation) (Commissio

September 17, 2024 EX-4

[Remainder of Page Intentionally Left Blank – Signature Page Follows]

EX-4 2 ef20035967ex4.htm EXHIBIT 4 Exhibit 4 520 Madison Avenue, New York, NY 10022 212.284.2300 Rule 10B5-1 Sales Plan Section 16 Affiliate I. Customer Information Capitalized terms that are used but not defined in this section shall have the meanings set forth in Part IV, Terms and Conditions. Seller: Jonathan Rothberg acting on his own and on behalf of NVR TR, LLC, JNR TR, LLC, JAR TR, LLC, EJR

September 17, 2024 SC 13D/A

QSI / Quantum-Si incorporated / ROTHBERG JONATHAN M - SC 13D/A Activist Investment

SC 13D/A 1 ef20035967sc13da.htm SC 13D/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D Under the Securities Exchange Act of 1934 (Amendment No. 2)* Quantum-Si Incorporated (Name of Issuer) Class A common stock, par value $0.0001 per share Class B common stock, par value $0.0001 per share (Title of Class of Securities) Class A common stock: 74765K105 Class B c

August 27, 2024 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 21, 2024 QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incorporation) (Commission

August 27, 2024 EX-99.1

Quantum-Si Announces New Executive Team Members to Accelerate the Evolution of the Company into a Leading Proteomic Tool Provider

Exhibit 99.1 Quantum-Si Announces New Executive Team Members to Accelerate the Evolution of the Company into a Leading Proteomic Tool Provider BRANFORD, Conn.-(BUSINESS WIRE)—August 27, 2024- Quantum-Si Incorporated (Nasdaq: QSI) (“Quantum-Si,” “QSI” or the “Company”), The Protein Sequencing Company™, today announced that Todd Bennett will join QSI as the Company’s new Chief Commercial Officer eff

August 13, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 12, 2024 QUANTUM-SI INCORP

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 12, 2024 QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incorporation) (Commission

August 13, 2024 EX-99.1

Corporate Presentation Quantum-Si: The Protein Sequencing Company™ Founded in 2013; NASDAQ (QSI) since June 2021 Experienced team from life sciences leaders including Illumina, PacBio, and Ion Torrent Launched the world’s first Next-Generation Protei

Exhibit 99.1 Corporate Presentation Forward Looking Statements This presentation includes "forward-looking statements" within the meaning of the "safe harbor" provisions of the United States Private Securities Litigation Reform Act of 1995. The actual results of Quantum-Si Incorporated (the “Company”) may differ from its expectations, estimates, and projections and, consequently, you should not re

August 7, 2024 EX-99.2

Use of Non-GAAP Financial Measures

Exhibit 99.2 Use of Non-GAAP Financial Measures In addition to financial results calculated in accordance with U.S. generally accepted accounting principles (“GAAP”), information containing non-GAAP financial measures for Quantum-Si Incorporated (the “Company”) was disclosed in the Company’s press release (the “Press Release”) dated August 7, 2024 announcing results for the three and six months en

August 7, 2024 EX-3.1

SECOND AMENDED AND RESTATED CERTIFICATE OF INCORPORATION OF HIGHCAPE CAPITAL ACQUISITION CORP.

Exhibit 3.1 SECOND AMENDED AND RESTATED CERTIFICATE OF INCORPORATION OF HIGHCAPE CAPITAL ACQUISITION CORP. HighCape Capital Acquisition Corp., a corporation organized and existing under the General Corporation Law of the State of Delaware (the “DGCL”), hereby certifies as follows: 1. The name of this corporation is HighCape Capital Acquisition Corp. The date of the filing of its original certifica

August 7, 2024 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2024 or o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-39486 QUANTUM-SI

August 7, 2024 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 7, 2024 QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incorporation) (Commission

August 7, 2024 EX-99.1

Quantum-Si Reports Second Quarter 2024 Financial Results Announces Release of Version 3 Sequencing Kit Announces Two Additional Kit Launches Expected by End of 2024

Exhibit 99.1 Quantum-Si Reports Second Quarter 2024 Financial Results Announces Release of Version 3 Sequencing Kit Announces Two Additional Kit Launches Expected by End of 2024 BRANFORD, Conn. - (BUSINESS WIRE) - August 7, 2024 - Quantum-Si Incorporated (Nasdaq: QSI) (“Quantum-Si,” “QSI” or the “Company”), The Protein Sequencing Company™, today announced financial results for the second quarter e

June 28, 2024 SC 13G/A

QSI / Quantum-Si incorporated / Radcliffe Capital Management, L.P. - SC 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G* (Rule 13d-102) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO § 240.13d-1(b), (c), AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO § 240.13d-2 (Amendment No. 2) Quantum-Si Inc [f/k/a HighCape Capital Acquisition Corp.] (Name of Issuer) Class A ordinary shares, $0.0001 par value (Title of Class of Sec

June 25, 2024 8-K

Regulation FD Disclosure, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 25, 2024 QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incorporation) (Commission F

June 25, 2024 EX-99.1

Corporate Presentation Quantum-Si: The Protein Sequencing CompanyTM Founded in 2013; NASDAQ (QSI) since June 2021 Experienced team from life sciences leaders including Illumina, PacBio and Ion Torrent Launched the world’s first, next-generation prote

Exhibit 99.1 Corporate Presentation Forward Looking Statements This presentation includes "forward-looking statements" within the meaning of the "safe harbor" provisions of the United States Private Securities Litigation Reform Act of 1995. The actual results of Quantum-Si Incorporated (the “Company”) may differ from its expectations, estimates, and projections and, consequently, you should not re

June 21, 2024 EX-24.1

POWER OF ATTORNEY

Exhibit 24.1 POWER OF ATTORNEY Know all by these present, that the undersigned hereby constitutes and appoints each of Jeffry Keyes, Chief Financial Officer, Christian LaPointe, Ph.D., General Counsel, and Linda Spero, Director of SEC Reporting, of Quantum-Si Incorporated (the “Company”), and Michael Fantozzi, Anne Bruno, Samantha Silver, Maura Foley and Robyn Frattali of Mintz, Levin, Cohn, Ferri

June 7, 2024 EX-16.1

June 7, 2024

Exhibit 16.1 June 7, 2024 Securities and Exchange Commission 100 F Street, N.E. Washington, D.C. 20549-7561 Dear Sirs/Madams: We have read Item 4.01 of Quantum-Si Incorporated’s Form 8-K dated June 7, 2024, and have the following comments: 1. We agree with the statements made in paragraphs 2, 3, 4, 5 and 6 therein. 2. We have no basis on which to agree or disagree with the statements made in parag

June 7, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 4, 2024 QUANTUM-SI INCORPORA

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 4, 2024 QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incorporation) (Commission Fi

May 30, 2024 EX-99.1

Quantum-Si Appoints Former Bio-Techne President and CEO, Chuck Kummeth, to serve as independent Chairman of the Board of Directors

Exhibit 99.1 Quantum-Si Appoints Former Bio-Techne President and CEO, Chuck Kummeth, to serve as independent Chairman of the Board of Directors BRANFORD, Conn.-(BUSINESS WIRE)—May 30, 2024- Quantum-Si Incorporated (Nasdaq: QSI) (“Quantum-Si,” “QSI” or the “Company”), The Protein Sequencing CompanyTM, today announced the appointment of Charles ("Chuck") Kummeth to the role of independent Chairman o

May 30, 2024 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 27, 2024 QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incorporation) (Commission Fi

May 24, 2024 8-K

Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 24, 2024 QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incorporation) (Commission Fi

May 17, 2024 8-K

Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year, Financial Statements and Exhibits, Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 15, 2024 QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incorporation) (Commission Fi

May 17, 2024 EX-3.1

CERTIFICATE OF AMENDMENT CERTIFICATE OF INCORPORATION QUANTUM-SI INCORPORATED

Exhibit 3.1 CERTIFICATE OF AMENDMENT OF CERTIFICATE OF INCORPORATION OF QUANTUM-SI INCORPORATED It is hereby certified that: FIRST: The name of the corporation is Quantum-Si Incorporated (the “Corporation”). SECOND: The Certificate of Incorporation is hereby further amended by striking out Article VIII, Part B in its entirety and by substituting in lieu of the following: (B) Number of Directors. S

May 9, 2024 EX-99.2

Use of Non-GAAP Financial Measures

Exhibit 99.2 Use of Non-GAAP Financial Measures In addition to financial results calculated in accordance with U.S. generally accepted accounting principles (“GAAP”), information containing non-GAAP financial measures for Quantum-Si Incorporated (the “Company”) was disclosed in the Company's press release (the “Press Release”) dated May 9, 2024 announcing results for the three months ended March 3

May 9, 2024 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2024 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-39486 QUANTUM-S

May 9, 2024 EX-99.1

Quantum-Si Reports First Quarter 2024 Financial Results Executed Full Commercial Launch of Platinum® Instrument Reaffirms Full Year 2024 Financial Guidance

Exhibit 99.1 Quantum-Si Reports First Quarter 2024 Financial Results Executed Full Commercial Launch of Platinum® Instrument Reaffirms Full Year 2024 Financial Guidance BRANFORD, Conn. - (BUSINESS WIRE) – May 9, 2024 - Quantum-Si Incorporated (Nasdaq: QSI) (“Quantum-Si,” “QSI” or the “Company”), The Protein Sequencing CompanyTM, today announced financial results for the first quarter ended March 3

May 9, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 9, 2024 QUANTUM-SI INCORPORAT

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 9, 2024 QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incorporation) (Commission Fil

April 30, 2024 DEFR14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. 1)

TABLE OF CONTENTS UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. 1) Filed by the Registrant ☒ Filed by a Party other than the Registrant  ☐ Check the appropriate box:  ☐ Preliminary Proxy Statement  ☐ Confidential, for Use of the Commission Only (as permitted by Rul

April 9, 2024 8-K

Regulation FD Disclosure, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 9, 2024 QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incorporation) (Commission F

April 9, 2024 EX-99.1

Corporate Presentation April 2024 Quantum-Si: The Protein Sequencing CompanyTM Founded in 2013; NASDAQ (QSI) since June 2021 Experienced team from life sciences leaders including Illumina, PacBio, and Ion Torrent Launched the world first, next-genera

Exhibit 99.1 Corporate Presentation April 2024 Forward Looking Statements This presentation includes "forward-looking statements" within the meaning of the "safe harbor" provisions of the United States Private Securities Litigation Reform Act of 1995. The actual results of Quantum-Si Incorporated (the “Company”) may differ from its expectations, estimates, and projections and, consequently, you sh

April 1, 2024 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.  )

TABLE OF CONTENTS UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.  ) Filed by the Registrant ☒ Filed by a Party other than the Registrant  ☐ Check the appropriate box:  ☐ Preliminary Proxy Statement  ☐ Confidential, for Use of the Commission Only (as permitted by Rul

April 1, 2024 ARS

ARS

ANNUAL REPORT 2023 www.quantum-si.com UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K 侌 ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2023 or 侊 TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Numbe

April 1, 2024 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.  )

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.  ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☐ Defi

March 22, 2024 PRE 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.  )

TABLE OF CONTENTS UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.  ) Filed by the Registrant ☒ Filed by a Party other than the Registrant  ☐ Check the appropriate box: ☒ Preliminary Proxy Statement  ☐ Confidential, for Use of the Commission Only (as permitted by Rule

March 21, 2024 EX-99.1

Quantum-Si Appoints Former Illumina and Cisco Systems Executive, Paula Dowdy, to its Board of Directors

Exhibit 99.1 Quantum-Si Appoints Former Illumina and Cisco Systems Executive, Paula Dowdy, to its Board of Directors BRANFORD, Conn.-(BUSINESS WIRE)—March 21, 2024- Quantum-Si Incorporated (Nasdaq: QSI) (“Quantum-Si,” “QSI” or the “Company”), The Protein Sequencing CompanyTM, today announced the appointment of Paula Dowdy, a senior executive with more than 35 years of experience across life scienc

March 21, 2024 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 20, 2024 QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incorporation) (Commission

March 11, 2024 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 8, 2024 QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incorporation) (Commission F

February 29, 2024 EX-10.16

QUANTUM-SI INCORPORATED NONEMPLOYEE DIRECTOR COMPENSATION POLICY (As Amended on February 27, 2024)

Exhibit 10.16 QUANTUM-SI INCORPORATED NONEMPLOYEE DIRECTOR COMPENSATION POLICY (As Amended on February 27, 2024) The Board of Directors of Quantum-Si Incorporated (the “Company”) has approved the following Nonemployee Director Compensation Policy (this “Policy”) to provide an inducement to obtain and retain the services of qualified persons to serve as members of the Company’s Board of Directors.

February 29, 2024 S-8

As filed with the Securities and Exchange Commission on February 29, 2024

As filed with the Securities and Exchange Commission on February 29, 2024 Registration No.

February 29, 2024 EX-99.2

Use of Non-GAAP Financial Measures

Exhibit 99.2 Use of Non-GAAP Financial Measures In addition to financial results calculated in accordance with U.S. generally accepted accounting principles (“GAAP”), information containing non-GAAP financial measures for Quantum-Si Incorporated (the “Company”) was disclosed in the Company's press release (the “Press Release”) dated February 29, 2024 announcing results for the three months and ful

February 29, 2024 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2023 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-39486 QUANTUM-SI INCORPORATED (

February 29, 2024 EX-10.133

QUANTUM-SI INCORPORATED Restricted Stock Unit Award Grant Notice Restricted Stock Unit Grant under the Company’s 2021 Equity Incentive Plan

Exhibit 10.13.3 QUANTUM-SI INCORPORATED Restricted Stock Unit Award Grant Notice Restricted Stock Unit Grant under the Company’s 2021 Equity Incentive Plan Name: Grant Number: Grant Date: Grant Type: Grant Shares: Vesting of Award: This Restricted Stock Unit Award shall vest as follows provided the Participant is an Employee, director or Consultant of the Company or of an Affiliate on the applicab

February 29, 2024 EX-FILING FEES

Calculation of Filing Fee Tables Form S-8 (Form Type) Quantum-Si Incorporated (Exact Name of Registrant as Specified in its Charter) Table 1: Newly Registered Securities Security Type Security Class Title Fee Calculation Rule Amount Registered(1) Pro

Exhibit 107 Calculation of Filing Fee Tables Form S-8 (Form Type) Quantum-Si Incorporated (Exact Name of Registrant as Specified in its Charter) Table 1: Newly Registered Securities Security Type Security Class Title Fee Calculation Rule Amount Registered(1) Proposed Maximum Offering Price Per Unit(2) Maximum Aggregate Offering Price Fee Rate Amount of Registration Fee Equity Class A common stock, par value $0.

February 29, 2024 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 29, 2024 QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incorporation) (Commissi

February 29, 2024 EX-97

QUANTUM-SI INCORPORATED CLAWBACK POLICY

Exhibit 97 QUANTUM-SI INCORPORATED CLAWBACK POLICY I. Introduction The Board of Directors (the “Board”) of Quantum-Si Incorporated (the “Company”) believes that it is in the best interests of the Company and its shareholders to create and maintain a culture that emphasizes integrity and accountability and that reinforces the Company’s pay-for-performance compensation philosophy. The Board has ther

February 29, 2024 EX-99.1

Quantum-Si Reports Fourth Quarter and Full Year 2023 Financial Results Finalizing Commercial Readiness for Expected Full Commercial Launch by the End of Q1 2024 Releases Full Year 2024 Financial Guidance

Exhibit 99.1 Quantum-Si Reports Fourth Quarter and Full Year 2023 Financial Results Finalizing Commercial Readiness for Expected Full Commercial Launch by the End of Q1 2024 Releases Full Year 2024 Financial Guidance BRANFORD, Conn. - (BUSINESS WIRE) – Feb. 29, 2024 - Quantum-Si Incorporated (Nasdaq: QSI) (“Quantum-Si,” “QSI” or the “Company”), The Protein Sequencing CompanyTM, today announced fin

February 29, 2024 EX-4.1

DESCRIPTION OF THE REGISTRANT’S SECURITIES

Exhibit 4.1 DESCRIPTION OF THE REGISTRANT’S SECURITIES The following summary of the material terms of the capital stock of Quantum-Si Incorporated (formerly HighCape Capital Acquisition Corp.) is not intended to be a complete summary of the rights and preferences of such securities, and is qualified by reference to our Second Amended and Restated Certificate of Incorporation, as amended (the “Char

February 13, 2024 SC 13G

QSI / Quantum-Si incorporated / Nikko Asset Management Americas, Inc. - SC 13G Passive Investment

SC 13G 1 ef20021430sc13g.htm SC 13G UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. n/a)* Quantum-Si Inc. (Name of Issuer) Class A common stock, par value $0.0001 per share (Title of Class of Securities) 74765K105 (CUSIP Number) December 31, 2023 (Date of Event Which Requires Filing of this Statement) Che

February 5, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 5, 2024 QUANTUM-SI INCOR

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 5, 2024 QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incorporation) (Commissio

February 5, 2024 SC 13G

QSI / Quantum-Si incorporated / Sumitomo Mitsui Trust Holdings, Inc. Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. n/a)* QUANTUM-SI INCORPORATED (Name of Issuer) Class A common stock, par value $0.0001 per share (Title of Class of Securities) 74765K105 (CUSIP Number) December 31, 2023 (Date of Event which Requires Filing of this Statement) Check the appropriate box to de

February 5, 2024 EX-99.1

Quantum-Si Expands Proteome Coverage and Increases Sequencing Output with New Enhancements to Its Next-Generation Protein Sequencing™ Platform Addition of another amino acid recognizer combined with improvements in surface chemistry, reagents and sof

Exhibit 99.1 Quantum-Si Expands Proteome Coverage and Increases Sequencing Output with New Enhancements to Its Next-Generation Protein Sequencing™ Platform Addition of another amino acid recognizer combined with improvements in surface chemistry, reagents and software will offer Platinum users greater sequencing output and coverage per sample BRANFORD, Conn. – (BUSINESS WIRE) – February 5, 2024 -

January 29, 2024 SC 13G/A

QSI / Quantum-Si incorporated / BlackRock Inc. Passive Investment

us74765k1051012924.txt SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No: 1) Quantum-Si Inc - (Name of Issuer) Common Stock - (Title of Class of Securities) 74765K105 - (CUSIP Number) December 31, 2023 - (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to whi

January 29, 2024 SC 13G/A

QSI / Quantum-Si incorporated / ARK Investment Management LLC - SC 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 SCHEDULE 13G UNDER THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No.

November 9, 2023 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2023 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-39486 QUANT

November 9, 2023 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 9, 2023 QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incorporation) (Commissio

November 9, 2023 EX-99.2

Use of Non-GAAP Financial Measures

Exhibit 99.2 Use of Non-GAAP Financial Measures In addition to financial results calculated in accordance with U.S. generally accepted accounting principles (“GAAP”), information containing non-GAAP financial measures for Quantum-Si Incorporated (the “Company”) was disclosed in the Company's press release (the “Press Release”) dated November 9, 2023 announcing results for the three and nine months

November 9, 2023 EX-99.1

Quantum-Si Reports Third Quarter 2023 Financial Results

Exhibit 99.1 Quantum-Si Reports Third Quarter 2023 Financial Results BRANFORD, Conn. - (BUSINESS WIRE) – Nov. 9, 2023 - Quantum-Si Incorporated (Nasdaq: QSI) (“Quantum-Si,” “QSI” or the “Company”), The Protein Sequencing CompanyTM, today announced financial results for the third quarter ended September 30, 2023. Third Quarter Highlights ● Recorded revenue of $223,000 in the third quarter of 2023 a

September 21, 2023 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 15, 2023 QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incorporation) (Commiss

September 21, 2023 EX-99.1

Quantum-Si Appoints Biotech Executive and Entrepreneur, Amir Jafri, to its Board of Directors

Exhibit 99.1 Quantum-Si Appoints Biotech Executive and Entrepreneur, Amir Jafri, to its Board of Directors BRANFORD, Conn. - (BUSINESS WIRE) - September 21, 2023 – Quantum-Si Incorporated (Nasdaq: QSI) (“Quantum-Si,” “QSI” or the “Company”), The Protein Sequencing Company™, today announced the appointment of Amir Jafri, President and CEO of Immunicom, Inc., to its Board of Directors. “Amir’s leade

September 13, 2023 SC 13D/A

QSI / Quantum-Si Incorporated - Class A / ROTHBERG JONATHAN M - SC 13D/A Activist Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D Under the Securities Exchange Act of 1934 (Amendment No. 1)* Quantum-Si Incorporated (Name of Issuer) Class A common stock, par value $0.0001 per share Class B common stock, par value $0.0001 per share (Title of Class of Securities) Class A common stock: 74765K105 Class B common stock: Not Applicable (CUSIP Number

September 13, 2023 EX-3

Rule 10b5-1 Sales Plan

EX-3 2 ef20010600ex3.htm EXHIBIT 3 Exhibit 3 Rule 10b5-1 Sales Plan This Rule 10b5-1 Sales Plan is entered into on September 11, 2023 (this “Sales Plan”) between Dr. Jonathan Rothberg (“Seller”), acting on his own behalf and on behalf of each of: NVR TR, LLC, JNR TR, LLC, JAR TR, LLC, EJR TR, LLC and GBR TR, LLC (each a “Selling Entity”), and Jefferies LLC (“Broker”), acting as agent for Seller. R

September 5, 2023 EX-10.1

1

Exhibit 10.1 August 30, 2023 Patrick Schneider Re: Separation Agreement Dear Patrick: The purpose of this letter agreement (this “Agreement”) is to confirm the end of your employment with Quantum-Si Incorporated (the “Company”) as of August 31, 2023 (the “Separation Date”), and to set forth the terms of your separation from Quantum-Si Incorporated (“Company”). Payment of the Separation Benefits de

September 5, 2023 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 1, 2023 QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incorporation) (Commissi

August 29, 2023 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Costs Associated with Exit or Disposal Activities

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 26, 2023 QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incorporation) (Commission

August 18, 2023 LETTER

LETTER

United States securities and exchange commission logo August 18, 2023 Jeffrey Hawkins Chief Executive Officer Quantum-Si Incorporated 29 Business Park Drive Branford, Connecticut 06405 Re: Quantum-Si Incorporated Registration Statement on Form S-3 Filed August 11, 2023 File No.

August 18, 2023 CORRESP

QUANTUM-SI INCORPORATED 29 Business Park Drive Branford, CT 06405

QUANTUM-SI INCORPORATED 29 Business Park Drive Branford, CT 06405 August 18, 2023 VIA EDGAR United States Securities and Exchange Commission Division of Corporation Finance 100 F Street, N.

August 11, 2023 EX-FILING FEES

Calculation of Filing Fee Table Form S-3 (Form Type) Quantum-Si Incorporated (Exact Name of Registrant as Specified in its Charter) Table 1: Newly Registered Securities

Exhibit 107 Calculation of Filing Fee Table Form S-3 (Form Type) Quantum-Si Incorporated (Exact Name of Registrant as Specified in its Charter) Table 1: Newly Registered Securities Security Type Security Class Title Fee Calculation or Carry Forward Rule Amount Registered Proposed Maximum Offering Price Per Unit Maximum Aggregate Offering Price Fee Rate Amount of Registration Fee Newly Registered Securities Fees to Be Paid Equity Class A common stock, $0.

August 11, 2023 EX-4.2

QUANTUM-SI INCORPORATED [ ] Trustee Dated as of [ ] Subordinated Debt Securities TABLE OF CONTENTS1

Exhibit 4.2 QUANTUM-SI INCORPORATED Issuer AND [ ] Trustee INDENTURE Dated as of [ ] Subordinated Debt Securities TABLE OF CONTENTS1 Page ARTICLE I DEFINITIONS 1 SECTION 1.01 Definitions of Terms 1 ARTICLE II ISSUE, DESCRIPTION, TERMS, EXECUTION, REGISTRATION AND EXCHANGE OF SECURITIES 4 SECTION 2.01 Designation and Terms of Securities 4 SECTION 2.02 Form of Securities and Trustee’s Certificate 6

August 11, 2023 EX-1.2

QUANTUM-SI INCORPORATED Class A Common Stock (par value $0.0001 per share) Having an Aggregate Offering Price of Up to $75,000,000 Equity Distribution Agreement

Exhibit 1.2 QUANTUM-SI INCORPORATED Class A Common Stock (par value $0.0001 per share) Having an Aggregate Offering Price of Up to $75,000,000 Equity Distribution Agreement August 11, 2023 Evercore Group L.L.C. 55 East 52nd Street, 36th Floor New York, New York 10055 Ladies and Gentlemen: Quantum-Si Incorporated, a Delaware corporation (the “Company”) confirms its agreement (this “Agreement”) with

August 11, 2023 S-3

As filed with the Securities and Exchange Commission on August 11, 2023

TABLE OF CONTENTS As filed with the Securities and Exchange Commission on August 11, 2023 Registration No.

August 11, 2023 EX-4.1

QUANTUM-SI INCORPORATED [ ] Trustee Dated as of [ ] Senior Debt Securities TABLE OF CONTENTS1

Exhibit 4.1 QUANTUM-SI INCORPORATED Issuer AND [ ] Trustee INDENTURE Dated as of [ ] Senior Debt Securities TABLE OF CONTENTS1 Page ARTICLE I DEFINITIONS 1 SECTION 1.01 Definitions of Terms 1 ARTICLE II ISSUE, DESCRIPTION, TERMS, EXECUTION, REGISTRATION AND EXCHANGE OF SECURITIES 4 SECTION 2.01 Designation and Terms of Securities 4 SECTION 2.02 Form of Securities and Trustee’s Certificate 6 SECTIO

August 7, 2023 EX-99.1

Quantum-Si Reports Second Quarter 2023 Financial Results

Exhibit 99.1 Quantum-Si Reports Second Quarter 2023 Financial Results BRANFORD, Conn. - (BUSINESS WIRE) - Aug. 7, 2023 - Quantum-Si Incorporated (Nasdaq: QSI) (“Quantum-Si,” “QSI” or the “Company”), The Protein Sequencing CompanyTM, today announced financial results for the second quarter ended June 30, 2023. Second Quarter Highlights ● Recognized revenue of $205,000 in the second quarter of 2023.

August 7, 2023 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2023 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-39486 QUANTUM-SI

August 7, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 7, 2023 QUANTUM-SI INCORPO

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 7, 2023 QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incorporation) (Commission

August 7, 2023 EX-3.1

SECOND AMENDED AND RESTATED CERTIFICATE OF INCORPORATION OF HIGHCAPE CAPITAL ACQUISITION CORP.

Exhibit 3.1 SECOND AMENDED AND RESTATED CERTIFICATE OF INCORPORATION OF HIGHCAPE CAPITAL ACQUISITION CORP. HighCape Capital Acquisition Corp., a corporation organized and existing under the General Corporation Law of the State of Delaware (the “DGCL”), hereby certifies as follows: 1. The name of this corporation is HighCape Capital Acquisition Corp. The date of the filing of its original certifica

July 20, 2023 EX-10.1

Supplemental Release

Exhibit 10.1 June 26, 2023 Michael McKenna Re: Separation Agreement Dear Mike: The purpose of this letter agreement (this “Agreement”) is to confirm the end of your employment with Quantum-Si Incorporated (the “Company”) as of July 31, 2023 (the “Separation Date”), and to set forth the terms of your separation from Quantum-Si Incorporated (“Company”). Payment of the Separation Benefits described b

July 20, 2023 EX-99.1

QUANTUM-SI INCORPORATED 2023 INDUCEMENT EQUITY INCENTIVE PLAN

Exhibit 99.1 QUANTUM-SI INCORPORATED 2023 INDUCEMENT EQUITY INCENTIVE PLAN 1. DEFINITIONS. Unless otherwise specified or unless the context otherwise requires, the following terms, as used in this Quantum-Si Incorporated 2023 Inducement Equity Incentive Plan, have the following meanings: Administrator means the Board of Directors, unless it has delegated power to act on its behalf to the Committee

July 20, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 18, 2023 QUANTUM-SI INCORPOR

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 18, 2023 QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incorporation) (Commission F

July 20, 2023 S-8

As filed with the Securities and Exchange Commission on July 20, 2023

As filed with the Securities and Exchange Commission on July 20, 2023 Registration No.

July 20, 2023 EX-FILING FEES

Calculation of Filing Fee Tables Form S-8 (Form Type) Quantum-Si Incorporated (Exact Name of Registrant as Specified in its Charter) Table 1: Newly Registered Securities Security Type Security Class Title Fee Calculation Rule Amount Registered(1) Pro

Exhibit 107 Calculation of Filing Fee Tables Form S-8 (Form Type) Quantum-Si Incorporated (Exact Name of Registrant as Specified in its Charter) Table 1: Newly Registered Securities Security Type Security Class Title Fee Calculation Rule Amount Registered(1) Proposed Maximum Offering Price Per Unit(2) Maximum Aggregate Offering Price Fee Rate Amount of Registration Fee Equity Class A common stock, par value $0.

July 20, 2023 EX-99.2

QUANTUM-SI INCORPORATED Stock Option Grant Notice Stock Option Grant under the Company’s 2023 Inducement Equity Incentive Plan

Exhibit 99.2 QUANTUM-SI INCORPORATED Stock Option Grant Notice Stock Option Grant under the Company’s 2023 Inducement Equity Incentive Plan Name: Grant Number: Grant Date: Vest Commencement Date: Grant Type: Non-Qualified Stock Option Grant Shares: Exercise Price: Expiration Date: Vesting Schedule: This Option shall become exercisable (and the Shares issued upon exercise shall be vested) as follow

July 10, 2023 SC 13G/A

QSI / Quantum-Si Incorporated - Class A / ARK Investment Management LLC - SC 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 SCHEDULE 13G UNDER THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No.

June 21, 2023 EX-99.1

Quantum-Si Announces the Appointment of Industry Veteran Johan Denecke as Senior Vice President of Operations

Exhibit 99.1 Quantum-Si Announces the Appointment of Industry Veteran Johan Denecke as Senior Vice President of Operations BRANFORD, Conn., June 21, 2023 — Quantum-Si Incorporated (Nasdaq: QSI) (“Quantum-Si,” “QSI” or the “Company”), The Protein Sequencing Company™, today announced the appointment of Johan Denecke as Senior Vice President of Operations, effective June 20, 2023. Mr. Denecke will be

June 21, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 16, 2023 QUANTUM-SI INCORPOR

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 16, 2023 QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incorporation) (Commission F

June 7, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 1, 2023 QUANTUM-SI INCORPORA

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 1, 2023 QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incorporation) (Commission Fi

June 7, 2023 EX-10.1

Supplemental Release

Exhibit 10.1 June 1, 2023 Claudia Drayton Re: Separation Agreement Dear Claudia: The purpose of this letter agreement (this “Agreement”) is to confirm the end of your employment with Quantum-Si Incorporated (the “Company”) as of June 30, 2022, and to set forth the terms of your separation from Quantum-Si Incorporated (“Company”). Payment of the Separation Benefits described below is contingent on

May 22, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 16, 2023 QUANTUM-SI INCORPORA

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 16, 2023 QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incorporation) (Commission Fi

May 22, 2023 EX-99.1

Quantum-Si Appoints Life Sciences and Diagnostics Industry Leader Jack Kenny to its Board of Directors

Exhibit 99.1 Quantum-Si Appoints Life Sciences and Diagnostics Industry Leader Jack Kenny to its Board of Directors GUILFORD, Conn. – May 22, 2023 – Quantum-Si Incorporated (Nasdaq: QSI) (“Quantum-Si,” “QSI” or the “Company”), The Protein Sequencing Company™, today announced the appointment of Jack Kenny, CEO of Meridian Bioscience, Inc., to its Board of Directors. “Jack brings a wealth of experie

May 16, 2023 EX-3.1

Certificate of Amendment to the Second Amended and Restated Certificate of Incorporation of Quantum-Si Incorporated, as filed with the Secretary of State of the State of Delaware on May 12, 2023

CERTIFICATE OF AMENDMENT OF CERTIFICATE OF INCORPORATION OF QUANTUM-SI INCORPORATED It is hereby certified that: FIRST: The name of the corporation is Quantum-Si Incorporated (the “Corporation”).

May 16, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 11, 2023 QUANTUM-SI INCORPORA

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 11, 2023 QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incorporation) (Commission Fi

May 11, 2023 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 11, 2023 QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incorporation) (Commission Fi

May 11, 2023 EX-99.1

Quantum-Si Reports First Quarter 2023 Financial Results Q1 2023 revenue $254,000 on orders of $449,000; gross margin 48.8% This was the Company’s first quarter of revenue generated on the sale of PlatinumTM instruments and kits Expect revenue to acce

Exhibit 99.1 Quantum-Si Reports First Quarter 2023 Financial Results Q1 2023 revenue $254,000 on orders of $449,000; gross margin 48.8% This was the Company’s first quarter of revenue generated on the sale of PlatinumTM instruments and kits Expect revenue to accelerate in the second half of 2023 based on robust business funnel GUILFORD, Conn. - (BUSINESS WIRE) - May 11, 2023 - Quantum-Si Incorpora

May 11, 2023 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2023 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-39486 QUANTUM-S

May 2, 2023 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 27, 2023 QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incorporation) (Commission

May 2, 2023 EX-10.1

April 27, 2023

Exhibit 10.1 April 27, 2023 Jeffry Keyes Dear Jeffry: On behalf of Quantum-Si, I am pleased to offer you a position as Chief Financial Officer beginning as soon as practical. You will report to Jeffrey Hawkins. Your annualized compensation in this position will consist of an annual base salary of $465,000 paid in twice monthly pay periods, less required deductions. For calendar year 2023, you will

May 2, 2023 EX-99.1

Quantum-Si Announces the Appointment of Jeff Keyes as Chief Financial Officer Appointment positions company for strategic growth in next-generation protein sequencing

Exhibit 99.1 Quantum-Si Announces the Appointment of Jeff Keyes as Chief Financial Officer Appointment positions company for strategic growth in next-generation protein sequencing GUILFORD, Conn., May 2, 2023 — Quantum-Si- Incorporated (Nasdaq: QSI) (“Quantum-Si,” “QSI” or the “Company”), The Protein Sequencing Company™, today announced the appointment of Jeff Keyes as its new Chief Financial Offi

April 28, 2023 ARS

ARS

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One) ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2022 or □ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-39486 QUANTUM-SI INC

March 29, 2023 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.  )

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.  ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☐ Defi

March 29, 2023 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

DEF 14A 1 ny20007250x4def14a.htm DEF 14A TABLE OF CONTENTS UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registrant  ☐ Check the appropriate box:  ☐ Preliminary Proxy Statement  ☐ Confidential, for Use of

March 17, 2023 PRE 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

TABLE OF CONTENTS UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registrant  ☐ Check the appropriate box: ☒ Preliminary Proxy Statement  ☐ Confidential, for Use of the Commission Only (as permitted by Rule

March 17, 2023 EX-10.14

Services Work Order No. 2 Protein Engineering Collaboration March 13, 2023

Exhibit 10.14 Services Work Order No. 2 Protein Engineering Collaboration March 13, 2023 This Services Work Order (“Work Order”) is made pursuant to, and is governed by, the Technology and Services Exchange Agreement (“TSEA”) between Quantum-Si Incorporated (“Q-Si”) and Protein Evolution, Inc. (“PEI”), joined by PEI on August 11, 2021 and made effective as of the Effective Time (as defined in the

March 17, 2023 EX-10.6

ADVISORY AGREEMENT

EX-10.6 3 brhc10049653ex10-6.htm EXHIBIT 10.6 Exhibit 10.6 ADVISORY AGREEMENT This ADVISORY AGREEMENT (the “Agreement”) is entered into as of November 1, 2022 (the “Effective Date”), by and between Quantum-Si Incorporated, a Delaware corporation (the “Company”), and Jonathan Rothberg, PhD. (“Dr. Rothberg”). WHEREAS, Dr. Rothberg serves on the Board of Directors of the Company (the “Board”) and as

March 17, 2023 EX-10.18

QUANTUM-SI INCORPORATED NONEMPLOYEE DIRECTOR COMPENSATION POLICY (As Amended on November 1, 2022)

EX-10.18 6 brhc10049653ex10-18.htm EXHIBIT 10.18 Exhibit 10.18 QUANTUM-SI INCORPORATED NONEMPLOYEE DIRECTOR COMPENSATION POLICY (As Amended on November 1, 2022) The Board of Directors of Quantum-Si Incorporated (the “Company”) has approved the following Nonemployee Director Compensation Policy (this “Policy”) to provide an inducement to obtain and retain the services of qualified persons to serve

March 17, 2023 S-8

As filed with the Securities and Exchange Commission on March 16, 2023

As filed with the Securities and Exchange Commission on March 16, 2023 Registration No.

March 17, 2023 EX-10.9

December 8, 2022

Exhibit 10.9 December 8, 2022 GRACE JOHNSTON Dear Grace: On behalf of Quantum-Si, I am pleased to offer you a position as Chief Commercial Officer beginning as soon as practical. You will report to Jeff Hawkins. Your annualized compensation in this position will consist of an annual base salary of $420,000 paid in twice monthly pay periods, less required deductions. For calendar year 2023, you wil

March 17, 2023 EX-4.1

DESCRIPTION OF THE REGISTRANT’S SECURITIES

Exhibit 4.1 DESCRIPTION OF THE REGISTRANT’S SECURITIES The following summary of the material terms of the capital stock of Quantum-Si Incorporated (formerly HighCape Capital Acquisition Corp.) is not intended to be a complete summary of the rights and preferences of such securities, and is qualified by reference to our Second Amended and Restated Certificate of Incorporation (the “Charter”), our A

March 17, 2023 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One) ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2022 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-39486 QUANTUM-SI INC

March 17, 2023 EX-21.1

Subsidiaries of Registrant

EX-21.1 7 brhc10049653ex21-1.htm EXHIBIT 21.1 Exhibit 21.1 Subsidiaries of Registrant Name Percentage Ownership State or Country of Organization Q-SI Operations Inc. 100% Delaware SAS Quantum-Si France 100% France

March 17, 2023 EX-FILING FEES

Calculation of Filing Fee Tables Form S-8 (Form Type) Quantum-Si Incorporated (Exact Name of Registrant as Specified in its Charter) Table 1: Newly Registered Securities Security Type Security Class Title Fee Calculation Rule Amount Registered(1) Pro

EX-FILING FEES 4 brhc10049719ex107.htm EXHIBIT 107 Exhibit 107 Calculation of Filing Fee Tables Form S-8 (Form Type) Quantum-Si Incorporated (Exact Name of Registrant as Specified in its Charter) Table 1: Newly Registered Securities Security Type Security Class Title Fee Calculation Rule Amount Registered(1) Proposed Maximum Offering Price Per Unit(2) Maximum Aggregate Offering Price Fee Rate Amou

March 15, 2023 8-K

Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 14, 2023 QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incorporation) (Commission

March 13, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 10, 2023 QUANTUM-SI INCORPO

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 10, 2023 QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incorporation) (Commission

March 6, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 6, 2023 QUANTUM-SI INCORPOR

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 6, 2023 QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incorporation) (Commission F

March 6, 2023 EX-99.1

Quantum-Si Reports Fourth Quarter and Fiscal Year 2022 Financial Results The Company began shipments of PlatinumTM instruments and expects to book revenue in Q1 2023 The Company projects an extended cash runway into 2026

Exhibit 99.1 Quantum-Si Reports Fourth Quarter and Fiscal Year 2022 Financial Results The Company began shipments of PlatinumTM instruments and expects to book revenue in Q1 2023 The Company projects an extended cash runway into 2026 GUILFORD, Conn. - (BUSINESS WIRE) - Quantum-Si Incorporated (Nasdaq: QSI) (“Quantum-Si,” “QSI” or the “Company”), The Protein Sequencing CompanyTM, today announced fi

March 2, 2023 8-K

Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 28, 2023 QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incorporation) (Commissi

March 2, 2023 EX-99.1

IN THE COURT OF CHANCERY FOR THE STATE OF DELAWARE

Exhibit 99.1 IN THE COURT OF CHANCERY FOR THE STATE OF DELAWARE IN RE QUANTUM-SI INCORPORATED ) ) ) C.A. No. 2023- VERIFIED PETITION FOR RELIEF UNDER 8 DEL. C. § 205 Petitioner Quantum-Si Incorporated (“Quantum-Si” or the “Company”) brings this petition (the “Petition”) for relief under Section 205 of the Delaware General Corporation Law (the “DGCL”): NATURE OF THE ACTION 1. The Company seeks to v

February 14, 2023 SC 13G/A

QSI / Quantum-Si Incorporated Class A / GLENVIEW CAPITAL MANAGEMENT, LLC - SC 13G/A Passive Investment

SC 13G/A 1 brhc10047998sc13ga.htm SC 13G/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 2)* Quantum-Si Inc. (Name of Issuer) Class A common stock, par value $0.0001 per share (Title of Class of Securities) 74765K105 (CUSIP Number) December 31, 2022 (Date of Event which Requires Filing of this Statement

February 10, 2023 SC 13G/A

QSI / Quantum-Si Incorporated Class A / ARK Investment Management LLC - SC 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 SCHEDULE 13G UNDER THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No.

February 3, 2023 SC 13G

QSI / Quantum-Si Incorporated Class A / BlackRock Inc. Passive Investment

us74765k1051020323.txt SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No: ) Quantum-Si Inc - (Name of Issuer) Common Stock - (Title of Class of Securities) 74765K105 - (CUSIP Number) December 31, 2022 - (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to whic

January 30, 2023 8-K

Costs Associated with Exit or Disposal Activities

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 30, 2023 QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incorporation) (Commissio

January 12, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 12, 2023 QUANTUM-SI INCOR

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 12, 2023 QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incorporation) (Commissio

January 9, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 9, 2023 QUANTUM-SI INCORP

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 9, 2023 QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incorporation) (Commission

January 9, 2023 EX-99.1

Quantum-Si Begins Commercial Shipments of the PlatinumTM Protein Sequencing System and Provides Business Updates at the 41st Annual J.P. Morgan Healthcare Conference Company Announces Commercial Shipments of Protein Sequencing System, Reveals New Par

Exhibit 99.1 Quantum-Si Begins Commercial Shipments of the PlatinumTM Protein Sequencing System and Provides Business Updates at the 41st Annual J.P. Morgan Healthcare Conference Company Announces Commercial Shipments of Protein Sequencing System, Reveals New Partnerships, and Reaffirms Commitment to Financial Discipline Launched in December 2022, Platinum is the First Commercially-Available Next-

December 20, 2022 EX-99.1

Quantum-Si Announces Commercial Availability of PlatinumTM, the World’s First Next-Generation Single-Molecule Protein Sequencing Platform Quantum-Si combines Time Domain Sequencing™ and Semiconductor Chip Technology to Advance Drug Discovery and Diag

Exhibit 99.1 Quantum-Si Announces Commercial Availability of PlatinumTM, the World?s First Next-Generation Single-Molecule Protein Sequencing Platform Quantum-Si combines Time Domain Sequencing? and Semiconductor Chip Technology to Advance Drug Discovery and Diagnostics and Accelerate Scientific Breakthroughs, Helping People to Live Healthier and Longer Lives Company Appoints Life Science Veteran

December 20, 2022 8-K

Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 20, 2022 QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incorporation) (Commissi

November 10, 2022 EX-FILING FEES

Calculation of Filing Fee Tables Form S-8 (Form Type) Quantum-Si Incorporated (Exact Name of Registrant as Specified in its Charter) Table 1: Newly Registered Securities Security Type Security Class Title Fee Calculation Rule Amount Registered(1) Pro

Exhibit 107 Calculation of Filing Fee Tables Form S-8 (Form Type) Quantum-Si Incorporated (Exact Name of Registrant as Specified in its Charter) Table 1: Newly Registered Securities Security Type Security Class Title Fee Calculation Rule Amount Registered(1) Proposed Maximum Offering Price Per Unit(2) Maximum Aggregate Offering Price Fee Rate Amount of Registration Fee Equity Class A common stock, par value $0.

November 10, 2022 EX-99.1

Quantum-Si Incorporated Non-Qualified Stock Option Grant Notice

Exhibit 99.1 Option No. Quantum-Si Incorporated Non-Qualified Stock Option Grant Notice 1. Name and Address of Participant: 2. Date of Option Grant: 3. Maximum Number of Shares for which this Option is exercisable: 4. Exercise (purchase) price per share: $ 5. Option Expiration Date: 6. Vesting Start Date: 7. Vesting Schedule: This Option shall become exercisable (and the Shares issued upon exercis

November 10, 2022 S-8

As filed with the Securities and Exchange Commission on November 10, 2022

As filed with the Securities and Exchange Commission on November 10, 2022 Registration No.

November 8, 2022 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2022 or ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-39486 QUANT

November 7, 2022 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 7, 2022 QUANTUM-SI INCOR

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 7, 2022 QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incorporation) (Commissio

November 7, 2022 EX-99.1

Quantum-Si Reports Third Quarter 2022 Financial Results

Exhibit 99.1 Quantum-Si Reports Third Quarter 2022 Financial Results GUILFORD, Conn. - (BUSINESS WIRE) - Nov. 07, 2022 - Quantum-Si Incorporated (Nasdaq: QSI) (?Quantum-Si,? ?QSI? or the ?Company?), a life sciences company commercializing the first next-generation, single-molecule protein sequencing platform, today announced financial results for the third quarter ending September 30, 2022. Recent

October 4, 2022 EX-99.1

Quantum-Si Appoints Jeff Hawkins as Chief Executive Officer Veteran Life Sciences Executive to Oversee Commercial Launch of Next-Generation Single-Molecule Protein Sequencing Platform

Exhibit 99.1 Quantum-Si Appoints Jeff Hawkins as Chief Executive Officer Veteran Life Sciences Executive to Oversee Commercial Launch of Next-Generation Single-Molecule Protein Sequencing Platform GUILFORD, Conn. - (BUSINESS WIRE) - Oct. 4, 2022 - Quantum-Si Incorporated (Nasdaq: QSI) (?Quantum-Si,? ?QSI? or the ?Company?), a life sciences company commercializing the first next-generation single-m

October 4, 2022 EX-10.1

2

Exhibit 10.1 October 2, 2022 Jeffrey Hawkins Dear Jeffrey: On behalf of Quantum-Si, I am pleased to offer you the position as Chief Executive Officer beginning no later than October 17, 2022 (your ?Start Date?). You will report to the Quantum-Si Board of Directors. Your annualized compensation in this position will consist of an annual base salary of $575,000 paid in twice monthly pay periods, les

October 4, 2022 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 2, 2022 QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incorporation) (Commission

August 8, 2022 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2022 or ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-39486 QUANTUM-SI

August 8, 2022 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 8, 2022 QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incorporation) (Commission

August 8, 2022 EX-99.1

Quantum-Si Reports Second Quarter 2022 Financial Results

Exhibit 99.1 Quantum-Si Reports Second Quarter 2022 Financial Results GUILFORD, Conn. - (BUSINESS WIRE) ? Aug. 08, 2022 - Quantum-Si Incorporated (Nasdaq: QSI) (?Quantum-Si,? ?QSI? or the ?Company?), a life sciences company commercializing the first next-generation, single-molecule protein sequencing platform, today announced financial results for the second quarter ending June 30, 2022. Recent Bu

July 20, 2022 424B3

QUANTUM-SI INCORPORATED Up to 72,558,225 Shares of Class A Common Stock Up to 19,937,500 Shares of Class B Common Stock Up to 135,000 Warrants

TABLE OF CONTENTS Filed Pursuant to Rule 424(b)(3) Registration No. 333-257676 333-263514 PROSPECTUS ? QUANTUM-SI INCORPORATED Up to 72,558,225 Shares of Class A Common Stock Up to 19,937,500 Shares of Class B Common Stock Up to 135,000 Warrants This prospectus relates to the issuance by us of up to an aggregate of 3,968,319 shares of our Class A common stock, par value $0.0001 per share (?Class A

July 20, 2022 424B3

QUANTUM-SI INCORPORATED Up to 72,558,225 Shares of Class A Common Stock Up to 19,937,500 Shares of Class B Common Stock Up to 135,000 Warrants

TABLE OF CONTENTS Filed Pursuant to Rule 424(b)(3) Registration No. 333-257676 333-263514 PROSPECTUS ? QUANTUM-SI INCORPORATED Up to 72,558,225 Shares of Class A Common Stock Up to 19,937,500 Shares of Class B Common Stock Up to 135,000 Warrants This prospectus relates to the issuance by us of up to an aggregate of 3,968,319 shares of our Class A common stock, par value $0.0001 per share (?Class A

July 15, 2022 POS462B

As filed with the U.S. Securities and Exchange Commission on July 15, 2022

TABLE OF CONTENTS As filed with the U.S. Securities and Exchange Commission on July 15, 2022 Registration No. 333-257676 333-263514 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Post-Effective Amendment No. 2 to FORM S-1 ON FORM S-3 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 Quantum-Si Incorporated (Exact name of registrant as specified in its charter) Delawa

July 15, 2022 POS AM

As filed with the U.S. Securities and Exchange Commission on July 15, 2022

TABLE OF CONTENTS As filed with the U.S. Securities and Exchange Commission on July 15, 2022 Registration No. 333-257676 333-263514 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Post-Effective Amendment No. 2 to FORM S-1 ON FORM S-3 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 Quantum-Si Incorporated (Exact name of registrant as specified in its charter) Delawa

June 28, 2022 SC 13D/A

QSI / Quantum-Si Incorporated Class A / Foresite Capital Fund IV, L.P. - SC 13D/A Activist Investment

CUSIP NO. 74765K105 13D Page 1 of 17 SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 13D (RULE 13d-101) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO RULE 13d-1(a) AND AMENDMENTS THERETO FILED PURSUANT TO RULE 13d-2(a) (Amendment No. 1)* Quantum-Si Incorporated (Name of Issuer) Class A Common Stock (Title of Class of Securities) 74765K105 (CUSIP Number) Dennis Ryan

June 16, 2022 424B3

QUANTUM-SI INCORPORATED Up to 78,841,853 Shares of Class A Common Stock Up to 19,937,500 Shares of Class B Common Stock Up to 135,000 Warrants

Filed Pursuant to Rule 424(b)(3) Registration No. 333-257676 333-263514 PROSPECTUS SUPPLEMENT NO. 6 To Prospectus dated March 3, 2022 QUANTUM-SI INCORPORATED Up to 78,841,853 Shares of Class A Common Stock Up to 19,937,500 Shares of Class B Common Stock Up to 135,000 Warrants This prospectus supplement no. 6 supplements the prospectus dated March 3, 2022 (the ?Prospectus?) relating to the issuance

June 16, 2022 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 10, 2022 QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incorporation) (Commission F

June 16, 2022 EX-99.1

Quantum-Si Appoints Vikram Bajaj, Ph.D., to Board of Directors

Exhibit 99.1 Quantum-Si Appoints Vikram Bajaj, Ph.D., to Board of Directors GUILFORD, Conn. - (BUSINESS WIRE) - Jun. 16, 2022 - Quantum-Si Incorporated (Nasdaq: QSI) (?Quantum-Si,? ?QSI? or the ?Company?), a life sciences company commercializing single molecule protein sequencing, today announced the appointment of Vikram Bajaj, Ph.D., co-founder and former Chief Scientific Officer of Verily (form

June 16, 2022 424B3

QUANTUM-SI INCORPORATED Up to 78,841,853 Shares of Class A Common Stock Up to 19,937,500 Shares of Class B Common Stock Up to 135,000 Warrants

Filed Pursuant to Rule 424(b)(3) Registration No. 333-257676 333-263514 PROSPECTUS SUPPLEMENT NO. 6 To Prospectus dated March 3, 2022 QUANTUM-SI INCORPORATED Up to 78,841,853 Shares of Class A Common Stock Up to 19,937,500 Shares of Class B Common Stock Up to 135,000 Warrants This prospectus supplement no. 6 supplements the prospectus dated March 3, 2022 (the ?Prospectus?) relating to the issuance

June 10, 2022 EX-10.1

June 10, 2022

Exhibit 10.1 June 10, 2022 Matthew Dyer Re: Separation Agreement Dear Matt: The purpose of this letter agreement (this ?Agreement?) is to confirm your resignation from Quantum-Si Incorporated (the ?Company?) as its Chief Business Officer as of June 15, 2022, and to set forth the terms of your separation from Quantum-Si Incorporated (?Company?). Payment of the Separation Benefits described below is

June 10, 2022 424B3

QUANTUM-SI INCORPORATED Up to 78,841,853 Shares of Class A Common Stock Up to 19,937,500 Shares of Class B Common Stock Up to 135,000 Warrants

Filed Pursuant to Rule 424(b)(3) Registration No. 333-257676 333-263514 PROSPECTUS SUPPLEMENT NO. 5 To Prospectus dated March 3, 2022 QUANTUM-SI INCORPORATED Up to 78,841,853 Shares of Class A Common Stock Up to 19,937,500 Shares of Class B Common Stock Up to 135,000 Warrants This prospectus supplement no. 5 supplements the prospectus dated March 3, 2022 (the ?Prospectus?) relating to the issuance

June 10, 2022 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 9, 2022 QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incorporation) (Commission Fi

June 10, 2022 424B3

QUANTUM-SI INCORPORATED Up to 78,841,853 Shares of Class A Common Stock Up to 19,937,500 Shares of Class B Common Stock Up to 135,000 Warrants

Filed Pursuant to Rule 424(b)(3) Registration No. 333-257676 333-263514 PROSPECTUS SUPPLEMENT NO. 5 To Prospectus dated March 3, 2022 QUANTUM-SI INCORPORATED Up to 78,841,853 Shares of Class A Common Stock Up to 19,937,500 Shares of Class B Common Stock Up to 135,000 Warrants This prospectus supplement no. 5 supplements the prospectus dated March 3, 2022 (the ?Prospectus?) relating to the issuance

May 16, 2022 424B3

QUANTUM-SI INCORPORATED Up to 78,841,853 Shares of Class A Common Stock Up to 19,937,500 Shares of Class B Common Stock Up to 135,000 Warrants

Filed Pursuant to Rule 424(b)(3) Registration No. 333-257676 333-263514 PROSPECTUS SUPPLEMENT NO. 4 To Prospectus dated March 3, 2022 QUANTUM-SI INCORPORATED Up to 78,841,853 Shares of Class A Common Stock Up to 19,937,500 Shares of Class B Common Stock Up to 135,000 Warrants This prospectus supplement no. 4 supplements the prospectus dated March 3, 2022 (the ?Prospectus?) relating to the issuance

May 16, 2022 8-K

Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 10, 2022 QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incorporation) (Commission Fi

May 16, 2022 424B3

QUANTUM-SI INCORPORATED Up to 78,841,853 Shares of Class A Common Stock Up to 19,937,500 Shares of Class B Common Stock Up to 135,000 Warrants

Filed Pursuant to Rule 424(b)(3) Registration No. 333-257676 333-263514 PROSPECTUS SUPPLEMENT NO. 4 To Prospectus dated March 3, 2022 QUANTUM-SI INCORPORATED Up to 78,841,853 Shares of Class A Common Stock Up to 19,937,500 Shares of Class B Common Stock Up to 135,000 Warrants This prospectus supplement no. 4 supplements the prospectus dated March 3, 2022 (the ?Prospectus?) relating to the issuance

May 10, 2022 424B3

QUANTUM-SI INCORPORATED Up to 78,841,853 Shares of Class A Common Stock Up to 19,937,500 Shares of Class B Common Stock Up to 135,000 Warrants

Filed Pursuant to Rule 424(b)(3) Registration No. 333-257676 333-263514 PROSPECTUS SUPPLEMENT NO. 3 To Prospectus dated March 3, 2022 QUANTUM-SI INCORPORATED Up to 78,841,853 Shares of Class A Common Stock Up to 19,937,500 Shares of Class B Common Stock Up to 135,000 Warrants This prospectus supplement no. 3 supplements the prospectus dated March 3, 2022 (the ?Prospectus?) relating to the issuance

May 10, 2022 424B3

QUANTUM-SI INCORPORATED Up to 78,841,853 Shares of Class A Common Stock Up to 19,937,500 Shares of Class B Common Stock Up to 135,000 Warrants

Filed Pursuant to Rule 424(b)(3) Registration No. 333-257676 333-263514 PROSPECTUS SUPPLEMENT NO. 3 To Prospectus dated March 3, 2022 QUANTUM-SI INCORPORATED Up to 78,841,853 Shares of Class A Common Stock Up to 19,937,500 Shares of Class B Common Stock Up to 135,000 Warrants This prospectus supplement no. 3 supplements the prospectus dated March 3, 2022 (the ?Prospectus?) relating to the issuance

May 10, 2022 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2022 or ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-39486 QUANTUM-S

May 9, 2022 EX-99.1

Quantum-Si Reports First Quarter 2022 Financial Results

Exhibit 99.1 Quantum-Si Reports First Quarter 2022 Financial Results GUILFORD, Conn. - (BUSINESS WIRE) ? May 09, 2022 - Quantum-Si Incorporated (Nasdaq: QSI) (?Quantum-Si,? ?QSI? or the ?Company?), a life sciences company commercializing single molecule protein sequencing, today announced financial results for the first quarter ending March 31, 2022. Recent Business Highlights ? Announced the appo

May 9, 2022 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 5, 2022 QUANTUM-SI INCORPORATED (Exact name of registrant as specified in its charter) Delaware 001-39486 85-1388175 (State or other jurisdiction of incorporation) (Commission Fil

May 9, 2022 EX-99.2

Quantum-Si Appoints Patrick Schneider as President and Chief Operating Officer

Exhibit 99.2 Quantum-Si Appoints Patrick Schneider as President and Chief Operating Officer GUILFORD, Conn.?(BUSINESS WIRE)-May 09, 2022- Quantum-Si Incorporated (Nasdaq: QSI) (?Quantum-Si,? ?QSI? or the ?Company?), a life sciences company commercializing single molecule protein sequencing, today announced the appointment of Patrick Schneider, Ph.D., as President and Chief Operating Officer (COO).

May 9, 2022 EX-10.1

April 26, 2022

Exhibit 10.1 April 26, 2022 Patrick Schneider Dear Patrick: On behalf of Quantum-Si, I am pleased to offer you the position as President and Chief Operating Officer beginning no later than June 1, 2022. You will report to the Quantum-Si CEO. Your annualized compensation in this position will consist of an annual base salary of $475,000 paid in twice monthly pay periods, less required deductions. B

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