EDIT / Editas Medicine, Inc. - Depositi SEC, Relazione annuale, dichiarazione di delega

Editas Medicine, Inc.
US ˙ NasdaqGS ˙ US28106W1036

Statistiche di base
LEI 5299000AON4Q9NT2JE42
CIK 1650664
SEC Filings
All companies that sell securities in the United States must register with the Securities and Exchange Commission (SEC) and file reports on a regular basis. These reports include company annual reports (10K, 10Q), news updates (8K), investor presentations (found in 8Ks), insider trades (form 4), ownership reports (13D, and 13G), and reports related to the specific securities sold, such as registration statements and prospectus. This page shows recent SEC filings related to Editas Medicine, Inc.
SEC Filings (Chronological Order)
Questa pagina fornisce un elenco completo e cronologico dei depositi SEC, esclusi i documenti di proprietà che forniamo altrove.
September 2, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 2, 2025 Editas Medicine

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 2, 2025 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission

September 2, 2025 EX-99

Editas Medicine Nominates EDIT-401, an LDLR-Targeted Medicine, as Lead In Vivo Development Candidate EDIT-401 achieved ~90% mean LDL-C reduction with single dose in non-human primates EDIT-401 on track for human proof-of-concept data by end of 2026 S

Exhibit 99.1 Editas Medicine Nominates EDIT-401, an LDLR-Targeted Medicine, as Lead In Vivo Development Candidate EDIT-401 achieved ~90% mean LDL-C reduction with single dose in non-human primates EDIT-401 on track for human proof-of-concept data by end of 2026 Strong cash position with operational runway into second quarter of 2027 Company-sponsored webinar on EDIT-401 today at 8:00 a.m. ET CAMBR

August 12, 2025 EX-99.1

Editas Medicine Announces Second Quarter 2025 Results and Business Updates Company to select lead development candidate in September; on track to file IND by mid-2026 and achieve human proof-of-concept by year-end 2026 First IND/CTA accepted for CD19

Editas Medicine Announces Second Quarter 2025 Results and Business Updates Company to select lead development candidate in September; on track to file IND by mid-2026 and achieve human proof-of-concept by year-end 2026 First IND/CTA accepted for CD19 HD Allo CAR T program as part of collaboration with Bristol Myers Squibb, triggering milestone payment to Editas Presented data at ASGCT, TIDES, and EHA that validate differentiated potential of Editas’ gene upregulation strategy and in vivo delivery platform technology Strong cash position with operational runway into the second quarter of 2027 CAMBRIDGE, Mass.

August 12, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 12, 2025 Editas Medicine,

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 12, 2025 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission F

August 12, 2025 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2025 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number 001

August 12, 2025 EX-3.1

Restated Certificate of Incorporation of the Registrant, as amended

ex31-restatedcharterasam Exhibit 3.1 RESTATED CERTIFICATE OF INCORPORATION OF EDITAS MEDICINE, INC. (originally incorporated on September 3, 2013 under the name Gengine, Inc.) FIRST: The name of the Corporation is Editas Medicine, Inc. SECOND: The address of the Corporation’s registered office in the State of Delaware is Corporation Trust Center, 1209 Orange Street, in the City of Wilmington, Coun

June 12, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 12, 2025 Editas Medicine, In

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 12, 2025 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission Fil

June 12, 2025 EX-99.1

Editas Medicine Reports Proprietary Targeted Lipid Nanoparticle Delivery in Non-Human Primates Enables In Vivo HBG1/2 Promoter Editing for Sickle Cell Disease and Beta Thalassemia at the European Hematology Association 2025 Congress in June Achieved

Editas Medicine Reports Proprietary Targeted Lipid Nanoparticle Delivery in Non-Human Primates Enables In Vivo HBG1/2 Promoter Editing for Sickle Cell Disease and Beta Thalassemia at the European Hematology Association 2025 Congress in June Achieved 58% mean editing at five months after a single dose using high efficiency HSC delivery, demonstrating therapeutically relevant editing levels using a clinically validated strategy Achievement supports development of a novel, in vivo approach to treating sickle cell disease and beta thalassemia.

June 2, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 29, 2025 Editas Medicine, Inc

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 29, 2025 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission File

June 2, 2025 EX-10.1

Amended and Restated 2015 Stock Incentive Plan

Editas Medicine, Inc. AMENDED AND RESTATED 2015 STOCK INCENTIVE PLAN 1.Purpose The purpose of this Amended and Restated 2015 Stock Incentive Plan (the “Plan”) of Editas Medicine, Inc., a Delaware corporation (the “Company”), is to advance the interests of the Company’s stockholders by enhancing the Company’s ability to attract, retain and motivate persons who are expected to make important contrib

June 2, 2025 EX-3.1

Certificate of Amendment of Restated Certificate of Incorporation of Editas Medicine, Inc.

Exhibit 3.1 CERTIFICATE OF AMENDMENT OF RESTATED CERTIFICATE OF INCORPORATION OF EDITAS MEDICINE, INC. (originally incorporated on September 3, 2013 under the name Gengine, Inc.) (Pursuant to Section 242 of the General Corporation Law of the State of Delaware) Editas Medicine, Inc. (the “Corporation”), a corporation organized and existing under and by virtue of the provisions of the General Corpor

May 14, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 14, 2025 Editas Medicine, Inc

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 14, 2025 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission File

May 14, 2025 EX-99.1

Editas Medicine Reports New In Vivo Data Highlighting the Potential of Editas’ Gene Upregulation Strategy in HSCs at the American Society of Gene and Cell Therapy Annual Meeting Data demonstrate therapeutically relevant editing levels using a clinica

EX-99.1 2 editasmedicineasgctinvivoh.htm EX-99.1 Editas Medicine Reports New In Vivo Data Highlighting the Potential of Editas’ Gene Upregulation Strategy in HSCs at the American Society of Gene and Cell Therapy Annual Meeting Data demonstrate therapeutically relevant editing levels using a clinically validated strategy, supporting its development as a novel, in vivo approach to treating sickle ce

May 13, 2025 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 13, 2025 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission File

May 13, 2025 EX-99.1

Editas Medicine Reports New In Vivo Proof of Concept Data in an Undisclosed Liver Target at the American Society of Gene and Cell Therapy Annual Meeting In vivo CRISPR Editing Results in Functional Upregulation of a Liver Target Protein and Meaningfu

Editas Medicine Reports New In Vivo Proof of Concept Data in an Undisclosed Liver Target at the American Society of Gene and Cell Therapy Annual Meeting In vivo CRISPR Editing Results in Functional Upregulation of a Liver Target Protein and Meaningful Reduction of Disease-Associated Biomarker in Mice CAMBRIDGE, Mass.

May 12, 2025 EX-99.1

Editas Medicine Announces First Quarter 2025 Results and Business Updates Company to share in vivo preclinical data demonstrating the successful use of targeted lipid nanoparticles to deliver HBG1/2 promoter editing cargo to hematopoietic stem and pr

Editas Medicine Announces First Quarter 2025 Results and Business Updates Company to share in vivo preclinical data demonstrating the successful use of targeted lipid nanoparticles to deliver HBG1/2 promoter editing cargo to hematopoietic stem and progenitor cells (HSPCs) at ASGCT this week Company will also share in vivo preclinical proof of concept to upregulate expression of a target liver protein to meaningfully reduce a common disease-associated biomarker at ASGCT this week and TIDES next week Remains on track to declare two in vivo gene editing development candidates via gene upregulation, one in HSCs and one in liver, in mid-2025 Strong cash position with operational runway into the second quarter of 2027 CAMBRIDGE, Mass.

May 12, 2025 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q (Mark One) ☐ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2025 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number 00

May 12, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 12, 2025 Editas Medicine, Inc

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 12, 2025 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission File

April 15, 2025 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant x Filed by a Party other than the Registrant o Check the appropriate box: o Preliminary Proxy Statement o Confidential, for Use of the Commission Only (a

April 15, 2025 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

TABLE OF CONTENTS UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant x Filed by a Party other than the Registrant o Check the appropriate box: o Preliminary Proxy Statement o Confidential, for Use of the

April 4, 2025 PRE 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

TABLE OF CONTENTS UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant x Filed by a Party other than the Registrant o Check the appropriate box: x Preliminary Proxy Statement o Confidential, for Use of the

March 20, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 18, 2025 Editas Medicine, I

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 18, 2025 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission Fi

March 5, 2025 EX-1.2

Common Stock Sales Agreement, dated as of May 14, 2021, by and between the Company and TD Securities (USA) LLC, as amended on February 28, 2024 and March 5, 2025

Exhibit 1.2 Editas Medicine, Inc. $300,000,000 COMMON STOCK SALES AGREEMENT May 14, 2021 Cowen and Company, LLC 599 Lexington Avenue New York, NY 10022 Ladies and Gentlemen: Editas Medicine, Inc., a Delaware corporation (the “Company”), confirms its agreement (this “Agreement”) with Cowen and Company, LLC (“Cowen”), as follows: 1.            Issuance and Sale of Shares. The Company agrees that, fr

March 5, 2025 EX-19.1

Insider Trading Policy

Exhibit 19.1 EDITAS MEDICINE, INC. Insider Trading Policy 1.BACKGROUND AND PURPOSE 1.1 Why Have We Adopted This Policy? The federal securities laws prohibit any member of the Board of Directors (a “Director”) or employee of Editas Medicine, Inc. (together with its subsidiaries, the “Company”) from purchasing or selling Company securities on the basis of material nonpublic information concerning th

March 5, 2025 EX-10.15

Separation Agreement, dated December 16, 2024 between the Registrant and Baisong Mei

ex1015separationagreemen 11 Hurley Street Cambridge, MA 02141 P 617-401-9000 F 617-494-0985 VIA HAND DELIVERY & ELECTRONIC MAIL December 16, 2024 Baisong Mei, M.

March 5, 2025 EX-FILING FEES

Filing fee table

Exhibit 107 Calculation of Filing Fee Tables Post-Effective Amendment No. 1 to Form S-3 (Form Type) Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Table 1: Newly Registered and Carry Forward Securities Security Type Security Class Title Fee Calculation or Carry Forward Rule Amount Registered Proposed Maximum Offering Price Per Unit Maximum Aggregate Offering Price Fee

March 5, 2025 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K (Mark One) x ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2024 or o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number 001-376

March 5, 2025 EX-10.25

Purchase and Sale Agreement, dated October 3, 2024, between the Registrant and DRI Healthcare Acquisitions LP

ex1025-purchaseandsaleag Execution Version Certain identified information has been excluded from the exhibit because it is both (i) not material and (ii) is the type of information that the registrant treats as private or confidential.

March 5, 2025 POSASR

As filed with the Securities and Exchange Commission on March 5, 2025

TABLE OF CONTENTS As filed with the Securities and Exchange Commission on March 5, 2025 Registration No.

March 5, 2025 S-8

As filed with the Securities and Exchange Commission on March 5, 2025

As filed with the Securities and Exchange Commission on March 5, 2025 Registration No.

March 5, 2025 POS AM

As filed with the Securities and Exchange Commission on March 5, 2025

TABLE OF CONTENTS As filed with the Securities and Exchange Commission on March 5, 2025 Registration No.

March 5, 2025 EX-99.1

Editas Medicine Announces Fourth Quarter and Full Year 2024 Results and Business Updates On track to declare two in vivo editing development candidates via gene upregulation, one in HSCs and one in liver, in mid-2025 Company to present further in viv

Editas Medicine Announces Fourth Quarter and Full Year 2024 Results and Business Updates On track to declare two in vivo editing development candidates via gene upregulation, one in HSCs and one in liver, in mid-2025 Company to present further in vivo HSC preclinical data and further in vivo preclinical data in one liver indication by year-end On track to establish one additional target cell type/tissue by year-end Strong cash position with operational runway into the second quarter of 2027 CAMBRIDGE, Mass.

March 5, 2025 EX-FILING FEES

Filing Fee Table

Exhibit 107 Calculation of Filing Fee Tables Form S-8 (Form Type) Editas Medicine, Inc.

March 5, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 5, 2025 Editas Medicine, In

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 5, 2025 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission Fil

January 13, 2025 EX-99.1

Editas Medicine Highlights New In Vivo Preclinical Proof of Concept Data, Anticipated 2025 Key Milestones, and Three-year Strategic Priorities

Exhibit 99.1 Editas Medicine Highlights New In Vivo Preclinical Proof of Concept Data, Anticipated 2025 Key Milestones, and Three-year Strategic Priorities •Achieved in vivo preclinical proof of concept of editing hematopoietic stem cells in non-human primates as a key step toward developing a novel in vivo treatment for sickle cell disease and beta thalassemia •Achieved in vivo editing of liver c

January 13, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 13, 2025 Editas Medicine,

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 13, 2025 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission

December 17, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 16, 2024 Editas Medicine

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 16, 2024 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission

December 12, 2024 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Costs Associated with Exit or Disposal Activities, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 11, 2024 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission

December 12, 2024 EX-99.1

Editas Medicine Announces Strategic Transition to in vivo Gene Editing Company with Intent to Achieve Human Proof of Concept in Approximately Two Years

Exhibit 99.1 Editas Medicine Announces Strategic Transition to in vivo Gene Editing Company with Intent to Achieve Human Proof of Concept in Approximately Two Years •Focus on in vivo CRISPR-edited medicines based on Editas researchers’ recent scientific progress in multiple tissues: -Achieved pre-clinical in vivo proof of concept of high level HBG1/2 promoter editing and HbF induction in a humaniz

December 10, 2024 EX-99.1

Editas Medicine Reports Updated Clinical Data from the RUBY Trial of Reni-cel in Patients with Severe Sickle Cell Disease at the American Society of Hematology (ASH) Annual Meeting Poster presentation at ASH on Monday, December 9 at 6:00 p.m. PT / 9:

Exhibit 99.1 Editas Medicine Reports Updated Clinical Data from the RUBY Trial of Reni-cel in Patients with Severe Sickle Cell Disease at the American Society of Hematology (ASH) Annual Meeting Poster presentation at ASH on Monday, December 9 at 6:00 p.m. PT / 9:00 p.m. ET CAMBRIDGE, Mass., Dec. 9, 2024 – Editas Medicine, Inc. (Nasdaq: EDIT), a leading gene editing company, will present updated sa

December 10, 2024 EX-3.1

Amended and Restated By-laws of the Registrant (incorporated by reference to Exhibit 3.1 to the Registrant’s Current Report on Form 8-K filed on December 10, 2024)

AMENDED AND RESTATED BY-LAWS OF EDITAS MEDICINE, INC. Exhibit 3.1 i TABLE OF CONTENTS Page ARTICLE I - STOCKHOLDERS 1.1 Place of Meetings .....................................................................................................1 1.2 Annual Meeting .......................................................................................................1 1.3 Special Meetings ..............

December 10, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 6, 2024 Editas Medicine,

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 6, 2024 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission

November 4, 2024 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2024 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Numbe

November 4, 2024 EX-99.1

Editas Medicine Announces Third Quarter 2024 Results and Business Updates Achieved in vivo preclinical proof of concept of HBG1/2 editing in hematopoietic stem and progenitor cells (HSPCs) using Editas Medicine’s proprietary targeted LNP in a key ste

Editas Medicine Announces Third Quarter 2024 Results and Business Updates Achieved in vivo preclinical proof of concept of HBG1/2 editing in hematopoietic stem and progenitor cells (HSPCs) using Editas Medicine’s proprietary targeted LNP in a key step to developing a novel in vivo treatment for sickle cell disease and beta thalassemia On track to share additional clinical and patient reported outc

November 4, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 4, 2024 Editas Medicine,

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 4, 2024 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission

October 22, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 22, 2024 Editas Medicine,

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 22, 2024 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission

October 22, 2024 EX-99

Editas Medicine Announces Progress Towards 2024 Goals, Including Achievement of In Vivo Preclinical Proof of Concept, and Strategic Update Achieved in vivo preclinical proof of concept of hematopoietic stem and progenitor cell editing by utilizing Ed

Editas Medicine Announces Progress Towards 2024 Goals, Including Achievement of In Vivo Preclinical Proof of Concept, and Strategic Update Achieved in vivo preclinical proof of concept of hematopoietic stem and progenitor cell editing by utilizing Editas Medicine’s proprietary targeted LNP as a key step forward toward developing a novel in vivo treatment for sickle cell disease and beta thalassemia Initiated process to partner or out-license reni-cel, to focus resources on in vivo pipeline development Company to present data and discuss strategic update in a Company-sponsored Webinar today at 8:00 a.

October 17, 2024 SC 13G/A

EDIT / Editas Medicine, Inc. / STATE STREET CORP Passive Investment

SC 13G/A 1 EditasMedicineInc.htm SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* EDITAS MEDICINE INC (Name of Issuer) COMMON STOCK (Title of Class of Securities) 28106W103 (CUSIP Number) September 30, 2024 (Date of Event Which Requires Filing of This Statement) Check the appropriate box to designate the rule pursuan

October 4, 2024 EX-99

Editas Medicine Announces $50+ Million Monetization Financing with DRI Healthcare Trust Strengthens balance sheet with non-dilutive capital to enable further pipeline development and related strategic priorities

Editas Medicine Announces $50+ Million Monetization Financing with DRI Healthcare Trust Strengthens balance sheet with non-dilutive capital to enable further pipeline development and related strategic priorities CAMBRIDGE, Mass.

October 4, 2024 8-K

Regulation FD Disclosure, Entry into a Material Definitive Agreement, Financial Statements and Exhibits, Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 3, 2024 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission F

August 7, 2024 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2024 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number 001

August 7, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 7, 2024 Editas Medicine, I

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 7, 2024 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission Fi

August 7, 2024 EX-99.1

Editas Medicine Announces Second Quarter 2024 Results and Business Updates On track to present additional clinical data from the RUBY trial and the EdiTHAL trial by year-end In vivo preclinical proof-of-concept for an undisclosed indication on-track

Editas Medicine Announces Second Quarter 2024 Results and Business Updates On track to present additional clinical data from the RUBY trial and the EdiTHAL trial by year-end In vivo preclinical proof-of-concept for an undisclosed indication on-track by year-end Strong financial position with runway into 2026 CAMBRIDGE, Mass.

June 27, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 27, 2024 Editas Medicine, In

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 27, 2024 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission Fil

June 14, 2024 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 14, 2024 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission Fil

June 14, 2024 EX-99.1

Editas Medicine Reports New Safety and Efficacy Data from the RUBY Trial of Reni-cel in 18 Patients with Sickle Cell Disease, Presented at the European Hematology Association (EHA) Annual Congress All patients treated in the RUBY trial are free of va

Editas Medicine Reports New Safety and Efficacy Data from the RUBY Trial of Reni-cel in 18 Patients with Sickle Cell Disease, Presented at the European Hematology Association (EHA) Annual Congress All patients treated in the RUBY trial are free of vaso-occlusive events post-renizgamglogene autogedtemcel (reni-cel) infusion Patients had early normalization of total hemoglobin with a mean within the normal range at >14 g/dL and rapid and sustained improvements in fetal hemoglobin well above levels of >40%.

June 14, 2024 EX-99.2

Editas Medicine Announces New Safety and Efficacy Data from the EdiTHAL Trial of Reni-cel in 7 Patients with Transfusion-dependent Beta Thalassemia, Presented at the European Hematology Association (EHA) Annual Congress All patients treated in the Ed

Editas Medicine Announces New Safety and Efficacy Data from the EdiTHAL Trial of Reni-cel in 7 Patients with Transfusion-dependent Beta Thalassemia, Presented at the European Hematology Association (EHA) Annual Congress All patients treated in the EdiTHAL trial maintained hemoglobin levels above the transfusion threshold and are transfusion-free post-renizgamglogene autogedtemcel (reni-cel) infusion Reni-cel was well-tolerated and demonstrated a safety profile consistent with myeloablative conditioning with busulfan and autologous hematopoietic stem cell transplant EHA EdiTHAL poster presentation on Friday, June 14 at 6 p.

May 31, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 30, 2024 Editas Medicine, Inc

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 30, 2024 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission File

May 8, 2024 EX-10.2

First Amendment, dated March 21, 2024, to the Second Amended and Restated Collaboration and License Agreement, between the Registrant and Juno

Exhibit 10.2 Certain identified information has been excluded from the exhibit because it is both (i) not material and (ii) information of the type that the registrant customarily and actually treats as private or confidential. Double asterisks denote omissions. FIRST AMENDMENT TO THE SECOND AMENDED AND RESTATED COLLABORATION AND LICENSE AGREEMENT This FIRST AMENDMENT TO THE SECOND AMENDED AND RES

May 8, 2024 EX-99.1

Editas Medicine Announces First Quarter 2024 Results and Business Updates Completed adult cohort enrollment and enrolled multiple patients in the adolescent cohort of the Phase 1/2/3 RUBY clinical trial of reni-cel for severe sickle cell disease On t

Editas Medicine Announces First Quarter 2024 Results and Business Updates Completed adult cohort enrollment and enrolled multiple patients in the adolescent cohort of the Phase 1/2/3 RUBY clinical trial of reni-cel for severe sickle cell disease On track to present additional clinical data from the RUBY trial and the EdiTHAL trial of reni-cel for transfusion-dependent beta-thalassemia in mid-2024 and additional updates by year-end 2024 Presenting pre-clinical data at ASGCT on in vivo capabilities to support development of transformative in vivo gene editing medicines Strong financial position with operational runway into 2026 CAMBRIDGE, Mass.

May 8, 2024 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2024 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number 00

May 8, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 8, 2024 Editas Medicine, Inc.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 8, 2024 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission File

April 16, 2024 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

TABLE OF CONTENTS UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant x Filed by a Party other than the Registrant o Check the appropriate box: o Preliminary Proxy Statement o Confidential, for Use of the

April 16, 2024 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant x Filed by a Party other than the Registrant o Check the appropriate box: o Preliminary Proxy Statement o Confidential, for Use of the Commission Only (a

February 28, 2024 EX-10.10

Form of Restricted Stock Unit Award Agreement under the 2015 Stock Incentive Plan

Exhibit 10.10 EDITAS MEDICINE, INC. RESTRICTED STOCK UNIT AGREEMENT Editas Medicine, Inc. (the “Company”) hereby grants the following restricted stock units pursuant to its 2015 Stock Incentive Plan. The terms and conditions attached hereto are also a part hereof. Notice of Grant Name of recipient (the “Participant”): Grant Date: Number of Restricted Stock Units (“RSUs”) granted: Number, if any, o

February 28, 2024 EX-1.2

Common Stock Sales Agreement, dated as of May 14, 2021, by and between the Company and Cowen and Company, LLC

Exhibit 1.2 Editas Medicine, Inc. $300,000,000 COMMON STOCK SALES AGREEMENT May 14, 2021 Cowen and Company, LLC 599 Lexington Avenue New York, NY 10022 Ladies and Gentlemen: Editas Medicine, Inc., a Delaware corporation (the “Company”), confirms its agreement (this “Agreement”) with Cowen and Company, LLC (“Cowen”), as follows: 1. Issuance and Sale of Shares. The Company agrees that, from time to

February 28, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 28, 2024 Editas Medicine

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 28, 2024 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission

February 28, 2024 EX-97

Dodd-Frank Compensation Recovery Policy

Exhibit 97 EDITAS MEDICINE, INC. Dodd-Frank Compensation Recovery Policy This Compensation Recovery Policy (this “Policy”) is adopted by Editas Medicine, Inc. (the “Company”) in accordance with Nasdaq Listing Rule 5608 (“Rule 5608”), which implements Rule 10D-1 under the Securities Exchange Act of 1934, as amended (the “Exchange Act”) (as promulgated pursuant to Section 954 of the Dodd-Frank Wall

February 28, 2024 EX-FILING FEES

Filing fee table

Exhibit 107 Calculation of Filing Fee Tables Form S-3 (Form Type) Editas Medicine, Inc.

February 28, 2024 EX-99.1

Editas Medicine Announces Fourth Quarter and Full Year 2023 Results and Business Updates Company aligned with FDA that RUBY is a single Phase 1/2/3 trial On track to present additional clinical data from the RUBY trial and the EdiTHAL trial of reni-c

Editas Medicine Announces Fourth Quarter and Full Year 2023 Results and Business Updates Company aligned with FDA that RUBY is a single Phase 1/2/3 trial On track to present additional clinical data from the RUBY trial and the EdiTHAL trial of reni-cel in mid-2024 and additional updates by year-end 2024 Initiated enrollment in the adolescent cohort in the RUBY trial Entered into a license agreement providing Vertex Pharmaceuticals a non-exclusive license for Cas9 Strong financial position with operational runway expected into 2026 CAMBRIDGE, Mass.

February 28, 2024 EX-4.2

Description of Registrant’s Securities Registered Pursuant to Section 12 of the Securities Exchange Act of 1934

Exhibit 4.2 DESCRIPTION OF THE REGISTRANT’S SECURITIES REGISTERED PURSUANT TO SECTION 12 OF THE SECURITIES EXCHANGE ACT OF 1934 As of December 31, 2023, Editas Medicine, Inc. (“we” or “us”) had one class of securities registered under Section 12 of the Securities Exchange Act of 1934, as amended: our common stock, par value $0.0001 per share. Description of Capital Stock The following description

February 28, 2024 EX-10.19

Form of Inducement Stock Option Agreement for the Registrant’s executive officers

Exhibit 10.19 Editas Medicine, Inc. Inducement Stock Option Agreement 1. Grant of Option. This agreement evidences the grant by Editas Medicine, Inc., a Delaware corporation (the “Company”), on [] (the “Grant Date”) to [] (the “Participant”), of an option to purchase, in whole or in part, on the terms provided herein, a total of [] shares (the “Shares”) of common stock, $0.0001 par value per share

February 28, 2024 EX-FILING FEES

Filing Fee Table

Exhibit 107 Calculation of Filing Fee Tables Form S-8 (Form Type) Editas Medicine, Inc.

February 28, 2024 EX-10.09

Form of Restricted Stock Agreement under 2015 Stock Incentive Plan

Exhibit 10.9 EDITAS MEDICINE, INC. Restricted Stock Agreement 2015 Stock Incentive Plan This Restricted Stock Agreement (this “Agreement”) is made as of the Grant Date set forth below between Editas Medicine, Inc., a Delaware corporation (the “Company”), and the Participant named below. NOTICE OF GRANT Name of Participant (the “Participant”): Grant Date: Number of shares of the restricted common s

February 28, 2024 EX-4.7

Form of Subordinated Note (incorporated by reference to Exhibit 4.7 to the Registrant’s Registration Statement on Form S-3 filed on February 28, 2024)

Exhibit 4.7 Form of Subordinated Note (FACE OF SECURITY) [Each Global Security shall bear substantially the following legend: UNLESS AND UNTIL IT IS EXCHANGED IN WHOLE OR IN PART FOR SECURITIES IN DEFINITIVE REGISTERED FORM, THIS SECURITY MAY NOT BE TRANSFERRED EXCEPT AS A WHOLE BY THE DEPOSITARY TO A NOMINEE OF THE DEPOSITARY OR BY A NOMINEE OF THE DEPOSITARY TO THE DEPOSITARY OR ANOTHER NOMINEE

February 28, 2024 EX-10.08

Form of Nonstatutory Stock Option Agreement under 2015 Stock Incentive Plan

Exhibit 10.8 EDITAS MEDICINE, INC. NONSTATUTORY STOCK OPTION AGREEMENT Editas Medicine, Inc. (the “Company”) hereby grants the following stock option pursuant to its 2015 Stock Incentive Plan. The terms and conditions attached hereto are also a part hereof. Notice of Grant Name of optionee (the “Participant”): Grant Date: Number of shares of the Company’s Common Stock subject to this option (“Shar

February 28, 2024 EX-10.27

Summary of Director Compensation Program

Exhibit 10.27 EDITAS MEDICINE DIRECTOR COMPENSATION Under this non-employee director compensation program, Editas Medicine (the “Company”) pays its non-employee directors retainers in cash. Each non-employee director receives a cash retainer for service on the Board and for service on each committee of which the director is a member. The chairmen of the Board and of each committee receives higher

February 28, 2024 S-3ASR

As filed with the Securities and Exchange Commission on February 28, 2024

As filed with the Securities and Exchange Commission on February 28, 2024 Registration No.

February 28, 2024 EX-4.5

Form of Subordinated Indenture (incorporated by reference to Exhibit 4.5 to the Registrant’s Registration Statement on Form S-3 filed on February 28, 2024)

Exhibit 4.5 EDITAS MEDICINE, INC. and Trustee INDENTURE Dated as of SUBORDINATED DEBT SECURITIES CROSS-REFERENCE TABLE 1 Section of Trust Indenture Act of 1939, as amended Section of Indenture 310(a) 6.09 310(b) 6.08 6.10 310(c) Inapplicable 311(a) 6.13 311(b) 6.13 311(c) Inapplicable 312(a) 4.01 4.04 312(b) 4.04(c) 312(c) 4.04(c) 313(a) 4.03 313(b) 4.03 313(c) 4.03 313(d) 4.03 314(a) 4.02 314(b)

February 28, 2024 S-8

As filed with the Securities and Exchange Commission on February 28, 2024

As filed with the Securities and Exchange Commission on February 28, 2024 Registration No.

February 28, 2024 EX-10.07

Form of Incentive Stock Option Agreement under 2015 Stock Incentive Plan

Exhibit 10.7 EDITAS MEDICINE, INC. INCENTIVE STOCK OPTION AGREEMENT Editas Medicine, Inc. (the “Company”) hereby grants the following stock option pursuant to its 2015 Stock Incentive Plan. The terms and conditions attached hereto are also a part hereof. Notice of Grant Name of optionee (the “Participant”): Grant Date: Number of shares of the Company’s Common Stock subject to this option (“Shares”

February 28, 2024 EX-4.4

Form of Senior Indenture (incorporated by reference to Exhibit 4.4 to the Registrant’s Registration Statement on Form S-3 filed on February 28, 2024)

Exhibit 4.4 EDITAS MEDICINE, INC. and Trustee INDENTURE Dated as of SENIOR DEBT SECURITIES CROSS-REFERENCE TABLE1 Section of Trust Indenture Act of 1939, as amended Section of Indenture 310(a) 6.09 310(b) 6.08 6.10 310(c) Inapplicable 311(a) 6.13 311(b) 6.13 311(c) Inapplicable 312(a) 4.01 4.04 312(b) 4.04(c) 312(c) 4.04(c) 313(a) 4.03 313(b) 4.03 313(c) 4.03 313(d) 4.03 314(a) 4.02 314(b) Inappli

February 28, 2024 EX-10.20

Form of Inducement Restricted Stock Unit Award Agreement for the Registrant’s executive officers

Exhibit 10.20 EDITAS MEDICINE, INC. INDUCEMENT RESTRICTED STOCK UNIT AGREEMENT Editas Medicine, Inc. (the “Company”) hereby grants the following restricted stock units. The terms and conditions attached hereto are also a part hereof. Notice of Grant Name of recipient (the “Participant”): [] Grant Date: [] Number of Restricted Stock Units (“RSUs”) granted: [] Number, if any, of RSUs that vest immed

February 28, 2024 EX-10.36

Omnibus Amendment, dated as of February 5, 2024, by and among the Registrant, Broad and Harvard

Exhibit 10.36 OMNIBUS AMENDMENT This Omnibus Amendment (the “Amendment”) is entered into as of February 5, 2024 (the “Amendment Effective Date”), by and between on the one hand, President and Fellows of Harvard College, an educational and charitable corporation existing under the laws and the constitution of the Commonwealth of Massachusetts, having a place of business at Smith Campus Center, Suit

February 28, 2024 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K (Mark One) x ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2023 or o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number 001-376

February 28, 2024 EX-4.6

Form of Senior Note (incorporated by reference to Exhibit 4.6 to the Registrant’s Registration Statement on Form S-3 filed on February 28, 2024)

Exhibit 4.6 Form of Senior Note (FACE OF SECURITY) [Each Global Security shall bear substantially the following legend: UNLESS AND UNTIL IT IS EXCHANGED IN WHOLE OR IN PART FOR SECURITIES IN DEFINITIVE REGISTERED FORM, THIS SECURITY MAY NOT BE TRANSFERRED EXCEPT AS A WHOLE BY THE DEPOSITARY TO A NOMINEE OF THE DEPOSITARY OR BY A NOMINEE OF THE DEPOSITARY TO THE DEPOSITARY OR ANOTHER NOMINEE OF THE

February 14, 2024 SC 13G/A

EDIT / Editas Medicine, Inc. / Deep Track Capital, LP Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934 (Amendment No.

February 13, 2024 SC 13G/A

EDIT / Editas Medicine, Inc. / VANGUARD GROUP INC - SCHEDULE 13G/A Passive Investment

SC 13G/A 1 tv0817-editasmedicineinc.htm SCHEDULE 13G/A SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Schedule 13G Under the Securities Exchange Act of 1934 (Amendment No.: 7)* Name of issuer: Editas Medicine Inc Title of Class of Securities: Common Stock CUSIP Number: 28106W103 Date of Event Which Requires Filing of this Statement: December 29, 2023 Check the appropriate box to designa

December 13, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 12, 2023 Editas Medicine

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 12, 2023 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission

December 13, 2023 EX-99.1

Editas Medicine and Vertex Pharmaceuticals Enter into Non-exclusive License Agreement for Cas9 Vertex Pharmaceuticals to obtain a non-exclusive license for Cas9 for CASGEVY™ (exagamglogene autotemcel) Agreement extends Editas Medicine’s cash runway i

ex991-pressreleaseddated Editas Medicine and Vertex Pharmaceuticals Enter into Non-exclusive License Agreement for Cas9 Vertex Pharmaceuticals to obtain a non-exclusive license for Cas9 for CASGEVY™ (exagamglogene autotemcel) Agreement extends Editas Medicine’s cash runway into 2026 CAMBRIDGE, Mass.

December 11, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 11, 2023 Editas Medicine

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 11, 2023 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission

December 11, 2023 EX-99.1

Editas Medicine Announces New EDIT-301 Safety and Efficacy Data in 17 Patients, Presented Today at the American Society of Hematology (ASH) Annual Meeting and in a Company-sponsored Webinar All RUBY patients with ≥5 months follow-up have achieved a n

ex991-pressreleasedatedd Editas Medicine Announces New EDIT-301 Safety and Efficacy Data in 17 Patients, Presented Today at the American Society of Hematology (ASH) Annual Meeting and in a Company-sponsored Webinar All RUBY patients with ≥5 months follow-up have achieved a normal hemoglobin level and a fetal hemoglobin level of >40% All patients treated in the RUBY trial are free of vaso-occlusive events post-EDIT-301 infusion EDIT-301 was well-tolerated and demonstrated a safety profile consistent with myeloablative conditioning with busulfan and autologous hematopoietic stem cell transplant EDIT-301 is now known as renizgamglogene autogedtemcel (reni-cel) Company-sponsored webinar on the RUBY and EdiTHAL data today at 1:00 p.

November 22, 2023 EX-10.1

Amended and Restated Severance Benefits Plan

Exhibit 10.1 Amended and Restated Severance Benefits Plan 1.Establishment of Plan. Editas Medicine, Inc., a Delaware corporation (the “Company”), hereby establishes an unfunded severance benefits plan (the “Plan”) that is intended to be a welfare benefit plan within the meaning of Section 3(1) of ERISA. The Plan is in effect for Covered Employees who experience a Covered Termination occurring afte

November 22, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 16, 2023 Editas Medicine

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 16, 2023 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission

November 3, 2023 EX-99.1

Editas Medicine Announces Third Quarter 2023 Results and Business Updates Company to provide a clinical update on the EDIT-301 RUBY trial for SCD and EdiTHAL trial for TDT in December at the American Society of Hematology (ASH) Annual Meeting and in

Exhibit 99.1 Editas Medicine Announces Third Quarter 2023 Results and Business Updates Company to provide a clinical update on the EDIT-301 RUBY trial for SCD and EdiTHAL trial for TDT in December at the American Society of Hematology (ASH) Annual Meeting and in a Company-sponsored webinar Granted Vor Bio a non-exclusive license for Cas9 patents for ex vivo HSC therapies for the treatment and prev

November 3, 2023 EX-10

Separation Agreement, dated October 6, 2023 between the Registrant and Bruce Eaton

separationagreement 11 Hurley Street Cambridge, MA 02141 P 617-401-9000 F 617-494-0985 VIA HAND DELIVERY & ELECTRONIC MAIL October 3, 2023 (as revised at your request on October 4, 2023) Bruce Eaton, Ph.

November 3, 2023 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2023 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Numbe

November 3, 2023 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 3, 2023 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission

October 10, 2023 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 03, 2023 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission

August 4, 2023 SC 13G

EDIT / Editas Medicine Inc / Deep Track Capital, LP Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No.

August 2, 2023 EX-10.2

Separation Agreement, dated May 16, 2023, between the Registrant and Michelle Robertson

Exhibit 10.2 11 Hurley Street Cambridge, MA 02141 P 617-401-9000 F 617-494-0985 VIA HAND DELIVERY May 11, 2023 (as revised at your request on May 15, 2023) Michelle Robertson Dear Michelle, As we discussed, your positions of Chief Financial Officer and Treasurer of Editas Medicine, Inc. (the “Company”) will end effective May 16, 2023 and, subject to your execution and compliance with the terms of

August 2, 2023 EX-10.1

Employment Offer Letter, dated May 12, 2023, between the Registrant and Erick Lucera

Exhibit 10.1 11 Hurley Street Cambridge, MA 02141 P 617-401-9000 F 617-494-0985 May 12, 2023 Erick Lucera Re: Offer of Employment Dear Erick, On behalf of Editas Medicine, Inc. (the “Company”), I am pleased to offer you employment with the Company. The purpose of this letter (the “Offer Letter”) is to set forth the terms of your employment with the Company, should you accept our offer. I am please

August 2, 2023 EX-10.3

Employment Offer Letter, dated July 3, 2023, between the Registrant and Linda C. Burkly

Exhibit 10.3 11 Hurley Street Cambridge, MA 02141 P 617-401-9000 F 617-494-0985 July 2, 2023 Linda Burkly, Ph.D. Re: Offer of Employment Dear Linda, On behalf of Editas Medicine, Inc. (the “Company”), I am pleased to offer you employment with the Company. The purpose of this letter (the “Offer Letter”) is to set forth the terms of your employment with the Company, should you accept our offer. I am

August 2, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 2, 2023 Editas Medicine, I

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 2, 2023 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission Fi

August 2, 2023 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2023 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number 001

August 2, 2023 EX-99.1

Editas Medicine Announces Second Quarter 2023 Results and Business Updates On track to dose 20 total patients in the EDIT-301 RUBY trial for SCD and provide a clinical update by year-end Commenced parallel patient dosing in the EDIT-301 EDITHAL trial

Exhibit 99.1 Editas Medicine Announces Second Quarter 2023 Results and Business Updates On track to dose 20 total patients in the EDIT-301 RUBY trial for SCD and provide a clinical update by year-end Commenced parallel patient dosing in the EDIT-301 EDITHAL trial for TDT and on track to provide a clinical update by year-end Strengthened Executive Team with Appointments of Erick Lucera as Chief Fin

June 15, 2023 424B5

12,500,000 Shares Common Stock

TABLE OF CONTENTS  Filed Pursuant to Rule 424(b)(5)  Registration No. 333-253715 PROSPECTUS SUPPLEMENT (To prospectus dated March 1, 2021) 12,500,000 Shares Common Stock Editas Medicine, Inc. is offering 12,500,000 shares of its common stock. Our common stock is listed on The Nasdaq Global Select Market under the symbol “EDIT.” The last reported sale price of our common stock on The Nasdaq Global

June 15, 2023 EX-1.1

Underwriting Agreement, June 14, 2023, by and among the Company, J.P. Morgan Securities LLC, Cowen and Company, LLC and Evercore Group, L.L.C.

Exhibit 1.1 12,500,000 Shares EDITAS MEDICINE, INC. COMMON STOCK, $0.0001 PAR VALUE PER SHARE UNDERWRITING AGREEMENT June 14, 2023 June 14, 2023 J.P. Morgan Securities LLC Cowen and Company, LLC Evercore Group L.L.C. As Representatives for the several Underwriters named in Schedule I hereto c/o J.P. Morgan Securities LLC 383 Madison Avenue New York, New York 10179 c/o Cowen and Company, LLC 599 Le

June 15, 2023 EX-99.1

Editas Medicine Announces Offering of Common Stock

Exhibit 99.1 Editas Medicine Announces Offering of Common Stock CAMBRIDGE, Mass., June 14, 2023 – Editas Medicine, Inc. (Nasdaq: EDIT), a clinical-stage genome editing company, today announced that it intends to offer and sell $125 million of shares of its common stock in an underwritten public offering. Editas Medicine intends to grant the underwriters a 30-day option to purchase up to an additio

June 15, 2023 EX-99.2

Editas Medicine Announces Pricing of Offering of Common Stock

Exhibit 99.2 Editas Medicine Announces Pricing of Offering of Common Stock CAMBRIDGE, Mass., June 14, 2023 – Editas Medicine, Inc. (Nasdaq: EDIT), a clinical-stage genome editing company, today announced the pricing of an underwritten offering of 12,500,000 shares of its common stock at a public offering price of $10.00 per share, before deducting underwriter discounts and commissions and estimate

June 15, 2023 EX-FILING FEES

Calculation of Filing Fee Tables

Exhibit 107 Calculation of Filing Fee Tables 424(b)(5) (Form Type) Editas Medicine, Inc.

June 15, 2023 8-K

Entry into a Material Definitive Agreement, Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 14, 2023 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission Fil

June 14, 2023 424B5

$125,000,000 of Shares Common Stock

TABLE OF CONTENTS The information in this preliminary prospectus supplement is not complete and may be changed.

June 9, 2023 EX-99.1

Editas Medicine Announces Positive Initial EDIT-301 Safety and Efficacy Data from the First Four Patients Treated in the RUBY Trial and the First Patient Treated in the EdiTHAL Trial EDIT-301 was well-tolerated and demonstrated a safety profile consi

Exhibit 99.1 Editas Medicine Announces Positive Initial EDIT-301 Safety and Efficacy Data from the First Four Patients Treated in the RUBY Trial and the First Patient Treated in the EdiTHAL Trial EDIT-301 was well-tolerated and demonstrated a safety profile consistent with myeloablative conditioning with busulfan and autologous hematopoietic stem cell transplant First two RUBY patients achieved no

June 9, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 9, 2023 Editas Medicine, Inc

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 9, 2023 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission File

June 5, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 1, 2023 Editas Medicine, Inc

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 1, 2023 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission File

May 17, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 11, 2023 Editas Medicine, Inc

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 11, 2023 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission File

May 5, 2023 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2023 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number 00

May 5, 2023 EX-99.1

Editas Medicine Announces First Quarter 2023 Results and Business Updates Company to provide a clinical update on the EDIT-301 Phase 1/2 RUBY trial for SCD in June at the European Hematology Association Congress (EHA) and in a Company-sponsored webin

Exhibit 99.1 Editas Medicine Announces First Quarter 2023 Results and Business Updates Company to provide a clinical update on the EDIT-301 Phase 1/2 RUBY trial for SCD in June at the European Hematology Association Congress (EHA) and in a Company-sponsored webinar On track to dose 20 total patients by year-end in the RUBY trial First patient in EDIT-301 EDITHAL trial for TDT dosed with successful

May 5, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 5, 2023 Editas Medicine, Inc.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 5, 2023 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission File

April 18, 2023 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.     )

TABLE OF CONTENTS UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.     ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of

April 18, 2023 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant x Filed by a Party other than the Registrant ¨ Check the appropriate box: ¨ Preliminary Proxy Statement ¨ Confidential, for Use of the Commission Only (a

April 13, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 11, 2023 Editas Medicine, I

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 11, 2023 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission Fi

March 14, 2023 EX-3.1

Amended and Restated By-laws of the Registrant

Exhibit 3.1 AMENDED AND RESTATED BY-LAWS OF EDITAS MEDICINE, INC. TABLE OF CONTENTS Page ARTICLE I - STOCKHOLDERS 1.1 Place of Meetings 1 1.2 Annual Meeting 1 1.3 Special Meetings 1 1.4 Notice of Meetings 1 1.5 Voting List 2 1.6 Quorum 2 1.7 Adjournments 3 1.8 Voting and Proxies 3 1.9 Action at Meeting 4 1.10 Nomination of Directors. 4 1.11 Notice of Business at Annual Meetings. 10 1.12 Conduct of

March 14, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 8, 2023 Editas Medicine, In

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 8, 2023 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission Fil

February 22, 2023 EX-FILING FEES

Filing Fee Table

Exhibit 107 Calculation of Filing Fee Tables Form S-8 (Form Type) Editas Medicine, Inc.

February 22, 2023 S-8

As filed with the Securities and Exchange Commission on February 22, 2023

As filed with the Securities and Exchange Commission on February 22, 2023 Registration No.

February 22, 2023 EX-21.1

Subsidiaries of the Registrant

EX-21.1 3 edit-20221231xex21d1.htm EX-21.1 Exhibit 21.1 Subsidiaries Entity State of Incorporation or Organization Editas Medicine, LLC Delaware Editas Securities Corporation Delaware

February 22, 2023 EX-99.1

Editas Medicine Announces Fourth Quarter and Full Year 2022 Results and Business Updates Commenced parallel patient dosing in the EDIT-301 RUBY trial for SCD, following clinical proof-of-concept demonstrated last quarter On track to provide clinical

Exhibit 99.1 Editas Medicine Announces Fourth Quarter and Full Year 2022 Results and Business Updates Commenced parallel patient dosing in the EDIT-301 RUBY trial for SCD, following clinical proof-of-concept demonstrated last quarter On track to provide clinical update for RUBY trial by mid-2023 and dose 20 total patients by year-end On track to dose first patient in EDIT-301 EDITHAL trial for TDT

February 22, 2023 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K (Mark One) ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2022 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number 001-376

February 22, 2023 EX-10.32

First Amendment to Lease Agreement, dated November 15, 2022 between Registrant and ARE-MA Region No. 55, LLC

Exhibit 10.32 FIRST AMENDMENT TO LEASE AGREEMENT THIS FIRST AMENDMENT TO LEASE AGREEMENT (this "First Amendment") is made as of November 15, 2022, by and between ARE-MA REGION NO. 55, LLC, a Delaware limited liability company ("Landlord"), and EDITAS MEDICINE, INC., a Delaware corporation ("Tenant"). RECITALS A.Landlord and Tenant are parties to that certain Lease Agreement dated as of February 12

February 22, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 22, 2023 Editas Medicine

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 22, 2023 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission

February 9, 2023 SC 13G/A

EDIT / Editas Medicine Inc / VANGUARD GROUP INC - SCHEDULE 13G/A Passive Investment

SC 13G/A 1 tv0792-editasmedicineincclas.htm SCHEDULE 13G/A SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Schedule 13G Under the Securities Exchange Act of 1934 (Amendment No.: 6)* Name of issuer: Editas Medicine Inc. Class A Title of Class of Securities: Common Stock CUSIP Number: 28106W103 Date of Event Which Requires Filing of this Statement: December 30, 2022 Check the appropriate b

January 9, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 7, 2023 Editas Medicine,

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 7, 2023 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission F

December 6, 2022 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 6, 2022 Editas Medicine,

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 6, 2022 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission

December 6, 2022 EX-99.1

Editas Medicine Announces Positive Safety and Efficacy Data from the First Two Patients Treated in the RUBY Trial of EDIT-301 for the Treatment of Severe Sickle Cell Disease EDIT-301 was well-tolerated and demonstrated a safety profile consistent wit

Exhibit 99.1 Editas Medicine Announces Positive Safety and Efficacy Data from the First Two Patients Treated in the RUBY Trial of EDIT-301 for the Treatment of Severe Sickle Cell Disease EDIT-301 was well-tolerated and demonstrated a safety profile consistent with myeloablative conditioning with busulfan and autologous hematopoietic stem cell transplant Both patients treated with EDIT-301 successf

November 17, 2022 8-K

Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 17, 2022 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission

November 17, 2022 EX-99.1

Editas Medicine Announces Clinical Data Demonstrating Proof of Concept of EDIT-101 from Phase 1/2 BRILLIANCE Trial EDIT-101 demonstrates a favorable safety profile across all dose cohorts Preliminary efficacy signals of consistent improvement in BCVA

Exhibit 99.1 Editas Medicine Announces Clinical Data Demonstrating Proof of Concept of EDIT-101 from Phase 1/2 BRILLIANCE Trial EDIT-101 demonstrates a favorable safety profile across all dose cohorts Preliminary efficacy signals of consistent improvement in BCVA plus additional efficacy endpoints seen in homozygous patients Achieved proof of concept and identified a responder population In view o

November 2, 2022 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2022 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Numbe

November 2, 2022 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 2, 2022 Editas Medicine,

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 2, 2022 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission

November 2, 2022 EX-99.1

Editas Medicine Announces Third Quarter 2022 Results and Business Updates Dosed second patient with EDIT-301 in the Phase 1/2 RUBY trial for sickle cell disease On track to announce initial preliminary clinical data from RUBY trial by year-end Comple

Exhibit 99.1 Editas Medicine Announces Third Quarter 2022 Results and Business Updates Dosed second patient with EDIT-301 in the Phase 1/2 RUBY trial for sickle cell disease On track to announce initial preliminary clinical data from RUBY trial by year-end Completed cell editing and currently scheduling first patient dosing with EDIT-301 in Phase 1/2 EDITHAL trial for TDT Company to provide a clin

August 3, 2022 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q

Table of Contents ? UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.

August 3, 2022 EX-99.1

Editas Medicine Announces Second Quarter 2022 Results and Business Updates Appointed Baisong Mei, M.D., Ph.D., Chief Medical Officer, strengthening senior leadership team Achieved successful engraftment of first patient treated with EDIT-301 for sick

Exhibit 99.1 Editas Medicine Announces Second Quarter 2022 Results and Business Updates Appointed Baisong Mei, M.D., Ph.D., Chief Medical Officer, strengthening senior leadership team Achieved successful engraftment of first patient treated with EDIT-301 for sickle cell disease; first clinical use of Editas-engineered AsCas12a enzyme FDA removed partial clinical hold for RUBY trial of EDIT-301 Con

August 3, 2022 EX-10.1

Employment Offer Letter, dated April 13, 2022, between the Registrant and Gilmore O’Neill

Exhibit 10.1 ? 11 Hurley Street ? Cambridge, MA 02141 ? 617-401-9000 ? 617-494-0985 ? April 13, 2022 ? By Electronic Mail ? Gilmore O?Neill, M.D. ? Dear Gilmore: ? On behalf of Editas Medicine, Inc., a Delaware corporation (the ?Company?), I am pleased to offer you employment with the Company. The purpose of this letter is to summarize the terms of your employment with the Company, should you acce

August 3, 2022 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 3, 2022 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission Fi

August 3, 2022 EX-10.3

Employment Offer Letter, dated June 14, 2022, between the Registrant and Baisong Mei

Exhibit 10.3 ? 11 Hurley Street ? Cambridge, MA 02141 ? P 617-401-9000 ? F 617-494-0985 ? June 09, 2022 ? ? ? Baisong Mei, M.D., Ph.D. ? ? ? Re: Offer of Employment ? ? Dear Baisong, On behalf of Editas Medicine, Inc. (the ?Company?), I am pleased to offer you employment with the Company. The purpose of this letter (the ?Offer Letter?) is to set forth the terms of your employment with the Company,

August 3, 2022 EX-10.2

Amendment to Employment Offer Letter, dated April 13, 2022, between the Registrant and James C. Mullen

Exhibit 10.2 ? ? 11 Hurley Street ? ? Cambridge, MA 02141 ? ? 617-401-9000 ? ? 617-494-0985 ? April 13, 2022 By Electronic Mail ? James C. Mullen ? Dear Jim: Reference is made to that certain Employment Offer Letter dated February 13, 2021 between Editas Medicine, Inc. (the ?Company?), and you regarding the terms of your employment with the Company (the ?Offer Letter?). This letter (the ?Amendment

August 3, 2022 EX-10.4

Amendment to RSU Agreement, dated May 24, 2022, between the Registrant and James C. Mullen

Exhibit 10.4 AMENDMENT TO RSU AGREEMENT Reference is made to that certain Restricted Stock Unit Agreement evidencing the restricted stock unit granted effective as of March 2, 2021 to James Mullen (the ?RSU Agreement?). The RSU Agreement is hereby amended as follows: 1.Section 7(b) of the RSU Agreement is amended by deleting the second and third sentence thereof such that Section 7(b) shall read i

June 13, 2022 8-K

Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 9, 2022 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission File

May 4, 2022 EX-99.1

Editas Medicine Announces First Quarter 2022 Results and Business Updates Appointed Gilmore O’Neill as CEO effective June 1, 2022; James C. Mullen to serve as Executive Chairman First pediatric patient dosed in Phase 1/2 BRILLIANCE trial of EDIT-101

Exhibit 99.1 Editas Medicine Announces First Quarter 2022 Results and Business Updates Appointed Gilmore O’Neill as CEO effective June 1, 2022; James C. Mullen to serve as Executive Chairman First pediatric patient dosed in Phase 1/2 BRILLIANCE trial of EDIT-101 for LCA10; clinical data update expected in 2H 2022 On track to dose first SCD patient in 1H 2022 and first TDT patient by year-end with

May 4, 2022 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 4, 2022 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission File

May 4, 2022 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q

Table of Contents ? UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.

April 26, 2022 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.     )

TABLE OF CONTENTS UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.     ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of

April 26, 2022 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

DEFA14A 1 tm223456d2defa14a.htm DEFA14A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant x Filed by a Party other than the Registrant ¨ Check the appropriate box: ¨ Preliminary Proxy Statement ¨ Confide

April 14, 2022 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 12, 2022 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission Fi

March 9, 2022 SC 13G/A

EDIT / Editas Medicine Inc / VANGUARD GROUP INC - SCHEDULE 13G/A Passive Investment

SC 13G/A 1 tv0013-editasmedicineincclas.htm SCHEDULE 13G/A SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Schedule 13G Under the Securities Exchange Act of 1934 (Amendment No.: 5)* Name of issuer: Editas Medicine Inc. Class A Title of Class of Securities: Common Stock CUSIP Number: 28106W103 Date of Event Which Requires Filing of this Statement: February 28, 2022 Check the appropriate b

February 24, 2022 EX-10.28

Amended Severance Benefits Plan

Exhibit 10.28 ? ? Severance Benefits Plan ? 1.Establishment of Plan. Editas Medicine, Inc., a Delaware corporation (the ?Company?), hereby establishes an unfunded severance benefits plan (the ?Plan?) that is intended to be a welfare benefit plan within the meaning of Section 3(1) of ERISA. The Plan is in effect for Covered Employees who experience a Covered Termination occurring after the Effectiv

February 24, 2022 EX-FILING FEES

Filing Fee Table

EX-FILING FEES 4 tmb-20220224xexfilingfees.htm EX-FILING FEES Exhibit 107 Calculation of Filing Fee Tables Form S-8 (Form Type) Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Table 1—Newly Registered Securities Security Type Security Class Title Fee Calculation Rule Amount Registered (1) Proposed Maximum Offering Price Per Unit Maximum Aggregate Offering Price Fee Rat

February 24, 2022 EX-99.1

Editas Medicine Announces Fourth Quarter and Full Year 2021 Results and Business Updates EDIT-101 Phase 1/2 BRILLIANCE trial enrolling mid-dose pediatric cohort; clinical data update expected in 2H 2022 EDIT-301 remains on track to dose first sickle

Exhibit 99.1 ? Editas Medicine Announces Fourth Quarter and Full Year 2021 Results and Business Updates ? EDIT-101 Phase 1/2 BRILLIANCE trial enrolling mid-dose pediatric cohort; clinical data update expected in 2H 2022 ? EDIT-301 remains on track to dose first sickle cell disease patient in 1H 2022 and first TDT patient in 2022 ? EDIT-103 for RHO-adRP and EDIT-202 for solid tumors advancing towar

February 24, 2022 S-8

As filed with the Securities and Exchange Commission on February 24, 2022

S-8 1 tmb-20220224xs8.htm S-8 As filed with the Securities and Exchange Commission on February 24, 2022 Registration No. 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM S-8 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 Editas Medicine, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 46-4097528 (State or Other Jurisdiction of Incorpor

February 24, 2022 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K (Mark One) ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2021 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number 001-376

February 24, 2022 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 24, 2022 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission

February 14, 2022 SC 13G/A

EDIT / Editas Medicine Inc / Nikko Asset Management Americas, Inc. - SC13G/A Passive Investment

SC 13G/A 1 brhc10033956sc13ga.htm SC13G/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 3)* Editas Medicine, Inc. (Name of Issuer) Common Stock, $0.0001 par value per share (Title of Class of Securities) 28106W103 (CUSIP Number) December 31, 2021 (Date of Event Which Requires Filing of this Statement) C

February 9, 2022 SC 13G/A

EDIT / Editas Medicine Inc / VANGUARD GROUP INC - SCHEDULE 13G/A Passive Investment

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Schedule 13G Under the Securities Exchange Act of 1934 (Amendment No.: 4)* Name of issuer: Editas Medicine Inc. Class A Title of Class of Securities: Common Stock CUSIP Number: 28106W103 Date of Event Which Requires Filing of this Statement: December 31, 2021 Check the appropriate box to designate the rule pursuant to which this Schedule is

February 9, 2022 SC 13G/A

EDIT / Editas Medicine Inc / ARK Investment Management LLC - SC 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 SCHEDULE 13G UNDER THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No.

February 7, 2022 8-K

Current Report

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 7, 2022 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission

February 4, 2022 SC 13G/A

EDIT / Editas Medicine Inc / Sumitomo Mitsui Trust Holdings, Inc. - AMENDMENT NO. 3 Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934 (Amendment No. 3)* Editas Medicine, Inc. (Name of Issuer) Common Stock, $0.0001 par value per share (Title of Class of Securities) 28106W103 (CUSIP Number) December 31, 2021 (Date of Event which Requires Filing of this Statement) Check the appropriate box to designate th

November 9, 2021 EX-10.3

Second Amendment to the Exclusive Patent License Agreement, by and between the Company and The General Hospital Corporation, d/b/a Massachusetts General Hospital, dated November 17, 2016

Exhibit 10.3 ? CONFIDENTIAL EXECUTION COPY ? Certain identified information has been excluded from the exhibit because it is both (i) not material and (ii) is the type of information that the registrant treats as private or confidential. Double asterisks denote omissions. SECOND AMENDMENT TO EXCLUSIVE PATENT LICENSE AGREEMENT ? MGH Agreement No.: A221317.02 ? This Second Amendment (?Second Amendme

November 9, 2021 EX-10.4

License Agreement, dated October 10, 2014, between the Registrant and Duke University

Exhibit 10.4 ? Certain identified information has been excluded from the exhibit because it is both (i) not material and (ii) is the type of information that the registrant treats as private or confidential. Double asterisks denote omissions. ? LICENSE AGREEMENT ? THIS Agreement is entered into this 10th day of October, 2014 (?Effective Date?) between DUKE UNIVERSITY, a nonprofit educational and r

November 9, 2021 EX-10.2

License Agreement, dated August 29, 2014, between the Registrant and The General Hospital Corporation, d/b/a Massachusetts General Hospital

Exhibit 10.2 ? Confidential Execution Copy ? Certain identified information has been excluded from the exhibit because it is both (i) not material and (ii) is the type of information that the registrant treats as private or confidential. Double asterisks denote omissions. ? THE GENERAL HOSPITAL CORPORATION ? EXCLUSIVE PATENT LICENSE AGREEMENT ? MGH Agreement No: A221317 MGH Case Nos: [**] ? This L

November 9, 2021 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q

Table of Contents ? UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.

November 9, 2021 EX-10.6

License Agreement, dated October 29, 2014, among the Registrant, the President and Fellows of Harvard College, and the Broad Institute, Inc.

Exhibit 10.6 ? EXECUTION VERSION ? Certain identified information has been excluded from the exhibit because it is both (i) not material and (ii) is the type of information that the registrant treats as private or confidential. Double asterisks denote omissions. ? License Agreement by and between PRESIDENT AND FELLOWS OF HARVARD COLLEGE, THE BROAD INSTITUTE, INC. and EDITAS MEDICINE, INC. October

November 9, 2021 EX-10.5

Letter Agreement, dated October 9, 2015, between the Registrant and Duke University

Exhibit 10.5 ? Certain identified information has been excluded from the exhibit because it is both (i) not material and (ii) is the type of information that the registrant treats as private or confidential. Double asterisks denote omissions. ? CONFIDENTIAL ? October 9, 2015 ? Barry Myers, MD, PhD Managing Director Office of Licensing & Ventures Duke University 2812 Erwin Road, Suite 306 Durham, N

November 9, 2021 EX-10.7

License and Collaboration Agreement, dated May 26, 2015, between the Registrant and Juno Therapeutics, Inc.

? Exhibit 10.7 ? Certain identified information has been excluded from the exhibit because it is both (i) not material and (ii) is the type of information that the registrant treats as private or confidential. Double asterisks denote omissions. ? COLLABORATION AND LICENSE AGREEMENT This COLLABORATION AND LICENSE AGREEMENT (this ?Agreement?), effective as of May 26, 2015 (the ?Effective Date?), is

November 9, 2021 EX-10.1

Employment Offer Letter, dated September 22, 2021, between the Registrant and Bruce Eaton

Exhibit 10.1 ? ? ? 11 Hurley Street Cambridge, MA 02141 P 617-401-9000 F 617-494-0985 ? ? ? September 22, 2021 ? ? Bruce Eaton ? ? Re: Employment as Chief Business Officer ? ? Dear Bruce, ? On behalf of Editas Medicine, Inc. (the ?Company?), I am pleased to inform you of your promotion to Executive Vice President and Chief Business Officer of the Company. The purpose of this letter (the ?Promotion

November 8, 2021 EX-99.1

Editas Medicine Announces Third Quarter 2021 Results and Business Updates EDIT-101 Phase 1/2 BRILLIANCE trial initial clinical data demonstrated favorable safety profile and preliminary evidence of clinical benefit; enrollment ongoing in adult high-d

Exhibit 99.1 ? Editas Medicine Announces Third Quarter 2021 Results and Business Updates ? EDIT-101 Phase 1/2 BRILLIANCE trial initial clinical data demonstrated favorable safety profile and preliminary evidence of clinical benefit; enrollment ongoing in adult high-dose and pediatric mid-dose cohorts ? EDIT-301 Phase 1/2 RUBY trial for the treatment of sickle cell disease currently enrolling study

November 8, 2021 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 8, 2021 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission

October 28, 2021 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 26, 2021 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission

September 29, 2021 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 29, 2021 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commissio

September 29, 2021 EX-99.1

Editas Medicine Announces Positive Initial Clinical Data from Ongoing Phase 1/2 BRILLIANCE Clinical Trial of EDIT-101 for LCA10 No serious adverse events or dose-limiting toxicities observed to date Efficacy signals in the mid-dose cohort provide ini

Exhibit 99.1 Editas Medicine Announces Positive Initial Clinical Data from Ongoing Phase 1/2 BRILLIANCE Clinical Trial of EDIT-101 for LCA10 No serious adverse events or dose-limiting toxicities observed to date Efficacy signals in the mid-dose cohort provide initial support for clinical benefits Treatment in the adult high-dose cohort continues and pediatric mid-dose cohort commencing Data presen

September 8, 2021 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 3, 2021 Editas Medicine

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 3, 2021 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission

August 5, 2021 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q

Table of Contents ? UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.

August 5, 2021 EX-10.3

Summary of Director Compensation Program

Exhibit 10.3 SUMMARY OF NON-EMPLOYEE DIRECTOR COMPENSATION PROGRAM Effective: June 15, 2021 The board of directors (the ?Board?) of Editas Medicine, Inc. (the ?Company?) has approved a non-employee director compensation program. Under this non-employee director compensation program, the Company pays its non-employee directors retainers in cash. Each non-employee director receives a cash retainer f

August 5, 2021 EX-10.2

Employment Offer Letter, dated April 19, 2021, between the Registrant and Mark S. Shearman

Exhibit 10.2 ? 11 Hurley Street Cambridge, MA 02141 P 617-401-9000 ? April 19, 2021 Dr. Mark Shearman Re: Offer of Employment Dear Mark, On behalf of Editas Medicine, Inc. (the ?Company?), I am pleased to offer you employment with the Company. The purpose of this letter (the ?Offer Letter?) is to set forth the terms of your employment with the Company, should you accept our offer. I am pleased to

August 4, 2021 EX-99.1

Editas Medicine Announces Second Quarter 2021 Results and Business Updates Enrolling first pediatric and adult high dose cohorts of EDIT-101 BRILLIANCE trial for LCA10 EDIT-101 initial clinical data planned for September 2021 EDIT-301 RUBY trial for

Exhibit 99.1 ? Editas Medicine Announces Second Quarter 2021 Results and Business Updates ? Enrolling first pediatric and adult high dose cohorts of EDIT-101 BRILLIANCE trial for LCA10 ? EDIT-101 initial clinical data planned for September 2021 ? EDIT-301 RUBY trial for sickle cell disease screening patients; first patient on track to be dosed by year-end ? Strengthened leadership with appointment

August 4, 2021 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 4, 2021 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission Fi

June 8, 2021 8-K

Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 3, 2021 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission File

May 21, 2021 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant x Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confidential, for Use of the Commission Only (a

May 14, 2021 EX-1.1

Common Stock Sales Agreement, dated as of May 14, 2021, by and between the Company and Cowen and Company, LLC

Exhibit 1.1 Editas Medicine, Inc. $300,000,000 COMMON STOCK SALES AGREEMENT May 14, 2021 Cowen and Company, LLC 599 Lexington Avenue New York, NY 10022 Ladies and Gentlemen: Editas Medicine, Inc., a Delaware corporation (the ?Company?), confirms its agreement (this ?Agreement?) with Cowen and Company, LLC (?Cowen?), as follows: 1. Issuance and Sale of Shares. The Company agrees that, from time to

May 14, 2021 8-K

Entry into a Material Definitive Agreement, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 14, 2021 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission File

May 14, 2021 424B5

CALCULATION OF REGISTRATION FEE

TABLE OF CONTENTS Filed Pursuant to Rule 424(b)(5) Registration Statement No. 333-253715? CALCULATION OF REGISTRATION FEE ? ? Title of Each Class of Securities Offered ? ? ? Proposed Maximum Aggregate Offering Price ? ? ? Amount of Registration Fee(1) ? Common Stock, par value $0.0001 per share ? ? ? ? $ 300,000,000 ? ? ? ? ? $ 32,730.00 ? ? ? (1) Calculated in accordance with Rule 457(o) under th

May 6, 2021 10-Q

Quarterly Report - 10-Q

Table of Contents ? UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.

May 5, 2021 EX-99.1

Editas Medicine Announces First Quarter 2021 Results and Update Strengthening Leadership by Adding Mark S. Shearman, Ph.D., as Chief Scientific Officer Advancing BRILLIANCE trial of EDIT-101 for LCA10; clinical data expected by year-end RUBY trial of

Exhibit 99.1 ? Editas Medicine Announces First Quarter 2021 Results and Update ? Strengthening Leadership by Adding Mark S. Shearman, Ph.D., as Chief Scientific Officer ? Advancing BRILLIANCE trial of EDIT-101 for LCA10; clinical data expected by year-end ? RUBY trial of EDIT-301 for sickle cell disease active and recruiting ? Preclinical ocular data presented at ARVO supports in vivo gene editing

May 5, 2021 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 5, 2021 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission File

April 20, 2021 DEF 14A

definitive proxy statement for the 2021 Annual Meeting of Stockholders, filed on April 20, 2021;

TABLE OF CONTENTS UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A? (Rule 14a-101) SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ?????) Filed by the Registrant ? Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? ? Confidential, for Use

April 20, 2021 DEFA14A

- DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant x Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confidential, for Use of the Commission Only (a

March 1, 2021 EX-4.6

Form of Senior Note

Exhibit 4.6 Form of Senior Note (FACE OF SECURITY) [Each Global Security shall bear substantially the following legend: UNLESS AND UNTIL IT IS EXCHANGED IN WHOLE OR IN PART FOR SECURITIES IN DEFINITIVE REGISTERED FORM, THIS SECURITY MAY NOT BE TRANSFERRED EXCEPT AS A WHOLE BY THE DEPOSITARY TO A NOMINEE OF THE DEPOSITARY OR BY A NOMINEE OF THE DEPOSITARY TO THE DEPOSITARY OR ANOTHER NOMINEE OF THE

March 1, 2021 S-3ASR

- S-3ASR

TABLE OF CONTENTS As filed with the Securities and Exchange Commission on March 1, 2021 Registration No.

March 1, 2021 S-8

- S-8

? As filed with the Securities and Exchange Commission on March 1, 2021 Registration No.

March 1, 2021 EX-4.7

Form of Subordinated Note

Exhibit 4.7 Form of Subordinated Note (FACE OF SECURITY) [Each Global Security shall bear substantially the following legend: UNLESS AND UNTIL IT IS EXCHANGED IN WHOLE OR IN PART FOR SECURITIES IN DEFINITIVE REGISTERED FORM, THIS SECURITY MAY NOT BE TRANSFERRED EXCEPT AS A WHOLE BY THE DEPOSITARY TO A NOMINEE OF THE DEPOSITARY OR BY A NOMINEE OF THE DEPOSITARY TO THE DEPOSITARY OR ANOTHER NOMINEE

March 1, 2021 EX-4.5

Form of Subordinated Indenture

Exhibit 4.5 EDITAS MEDICINE, INC. Trustee INDENTURE Dated as of SUBORDINATED DEBT SECURITIES CROSS-REFERENCE TABLE 1 Section of Trust Indenture Act of 1939, as amended Section of Indenture 310(a) 6.09 310(b) 6.08 6.10 310(c) Inapplicable 311(a) 6.13 311(b) 6.13 311(c) Inapplicable 312(a) 4.01 4.04 312(b) 4.04(c) 312(c) 4.04(c) 313(a) 4.03 313(b) 4.03 313(c) 4.03 313(d) 4.03 314(a) 4.02 314(b) Inap

March 1, 2021 EX-4.4

Form of Senior Indenture

Exhibit 4.4 EDITAS MEDICINE, INC. and Trustee INDENTURE Dated as of SENIOR DEBT SECURITIES CROSS-REFERENCE TABLE1 Section of Trust Indenture Act of 1939, as amended Section of Indenture 310(a) 6.09 310(b) 6.08 6.10 310(c) Inapplicable 311(a) 6.13 311(b) 6.13 311(c) Inapplicable 312(a) 4.01 4.04 312(b) 4.04(c) 312(c) 4.04(c) 313(a) 4.03 313(b) 4.03 313(c) 4.03 313(d) 4.03 314(a) 4.02 314(b) Inappli

February 26, 2021 10-K

Annual Report - 10-K

Table of Contents ? ? UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.

February 26, 2021 EX-10.13

Letter Agreement, dated February 15, 2021, by and between the Registrant and Cynthia Collins

? ? Exhibit 10.13 11 Hurley Street Cambridge, MA 02141 P 617-401-9000 F 617-494-0985 ? VIA ELECTRONIC MAIL February 4, 2021 (revised) Cynthia Collins Dear Cindy: As we discussed, your employment with Editas Medicine, Inc. (the ?Company?) will end effective February 15, 2021 (the ?Separation Date?). As we also discussed, you will be eligible to receive the severance benefits described in paragraph

February 26, 2021 EX-10.25

Summary of Director Compensation Program

Exhibit 10.25 SUMMARY OF NON-EMPLOYEE DIRECTOR COMPENSATION PROGRAM Effective: February 16, 2021 The board of directors (the ?Board?) of Editas Medicine, Inc. (the ?Company?) has approved a non-employee director compensation program. Under this non-employee director compensation program, the Company pays its non-employee directors retainers in cash. Each non-employee director receives a cash retai

February 26, 2021 EX-10.14

Employment Offer Letter, dated February 14, 2021, between the Registrant and James C. Mullen

Exhibit 10.14 ? ? ? ? ? 11 Hurley Street Cambridge, MA 02141 617-401-9000 617-494-0985 February 13, 2021 By Electronic Mail James C. Mullen Dear Jim: On behalf of Editas Medicine, Inc., a Delaware corporation (the ?Company?), I am pleased to offer you employment with the Company. The purpose of this letter is to summarize the terms of your employment with the Company, should you accept our offer:

February 26, 2021 EX-10.24

First Amendment to Sponsored Research Agreement, dated January 11, 2021, between the Registrant and Broad

Exhibit 10.24 Certain identified information has been excluded from this exhibit because it is both (i) not material and (ii) would likely cause competitive harm to the Company, if publicly disclosed. Double asterisks denote omissions. FIRST AMENDMENT TO SPONSORED RESEARCH AGREEMENT This Amendment (the ?SRA Amendment?) is entered into as of January 11, 2021 (the ?SRA Amendment Effective Date?), by

February 26, 2021 EX-10.18

Employment Offer Letter, dated September 25, 2020, between the Registrant and Lisa A. Michaels, M.D.

Exhibit 10.18 ? ? 11 Hurley Street Cambridge, MA 02141 P 617-401-9000 F 617-494-0985 September 25, 2020 Lisa A. Michaels, MD Re: Offer of Employment Dear Lisa, On behalf of Editas Medicine, Inc. (the ?Company?), I am pleased to offer you employment with the Company. The purpose of this letter (the ?Offer Letter?) is to set forth the terms of your employment with the Company, should you accept our

February 26, 2021 EX-10.32

Omnibus Amendment, dated as of January 11, 2021, by and between the Registrant and Broad

? Exhibit 10.32 Certain identified information has been excluded from this exhibit because it is both (i) not material and (ii) would likely cause competitive harm to the Company, if publicly disclosed. Double asterisks denote omissions. OMNIBUS AMENDMENT This Omnibus Amendment (the ?Amendment?) is entered into as of January 11, 2021 (the ?Amendment Effective Date?), by and between The Broad Insti

February 25, 2021 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 25, 2021 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission

February 25, 2021 EX-99.1

Editas Medicine Announces Fourth Quarter and Full Year 2020 Results and Update Strengthened Leadership by Appointing James (Jim) C. Mullen as President and Chief Executive Officer, and Lisa A. Michaels, M.D., as Chief Medical Officer Appointed Meeta

Exhibit 99.1 Editas Medicine Announces Fourth Quarter and Full Year 2020 Results and Update Strengthened Leadership by Appointing James (Jim) C. Mullen as President and Chief Executive Officer, and Lisa A. Michaels, M.D., as Chief Medical Officer Appointed Meeta Chatterjee, Ph.D., to Board of Directors Initiated dosing of adult mid-dose cohort of BRILLIANCE trial of EDIT-101 for LCA10 Initiated Ph

February 19, 2021 8-K/A

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K/A CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 4, 2021 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commissio

February 16, 2021 SC 13G/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 SCHEDULE 13G UNDER THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No. 3)* Editas Medicine, Inc. (Name of Issuer) Common Stock (Title of Class of Securities) (CUSIP Number) December

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 SCHEDULE 13G UNDER THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No.

February 11, 2021 SC 13G/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 2)* Editas Medicine, Inc.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 2)* Editas Medicine, Inc. (Name of Issuer) Common Stock, $0.0001 par value per share (Title of Class of Securities) 28106W103 (CUSIP Number) December 31, 2020 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the

February 10, 2021 SC 13G/A

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Schedule 13G Under the Securities Exchange Act of 1934 (Amendment No.: 3)*

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Schedule 13G Under the Securities Exchange Act of 1934 (Amendment No.: 3)* Name of issuer: Editas Medicine Inc. Title of Class of Securities: Common Stock CUSIP Number: 28106W103 Date of Event Which Requires Filing of this Statement: December 31, 2020 Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

February 8, 2021 EX-99.1

Editas Medicine Announces Appointment of James C. Mullen as Chief Executive Officer Cindy Collins to Step Down Effective February 15, 2021

Exhibit 99.1 Editas Medicine Announces Appointment of James C. Mullen as Chief Executive Officer Cindy Collins to Step Down Effective February 15, 2021 CAMBRIDGE, Mass., Feb. 8, 2021 – Editas Medicine, Inc. (Nasdaq: EDIT), a leading genome editing company, today announced that James (Jim) C. Mullen will succeed Cynthia (Cindy) Collins as Chief Executive Officer, effective February 15, 2021. Mr. Mu

February 8, 2021 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits - FORM 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 4, 2021 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 (State or Other Jurisdiction of Incorporation) (Commission File Number

February 5, 2021 SC 13G/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 2) *

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 2) * Editas Medicine, Inc. (Name of Issuer) Common Stock, $0.0001 par value per share (Title of Class of Securities) 28106W103 (CUSIP Number) December 31, 2020 (Date of Event which Requires Filing of this Statement) Check the appropriate box to designate the

January 29, 2021 SC 13G/A

SC 13G/A

us28106w1036012921.txt SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No: 3) EDITAS MEDICINE INC - (Name of Issuer) Common Stock - (Title of Class of Securities) 28106W103 - (CUSIP Number) December 31, 2020 - (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant t

January 21, 2021 424B5

CALCULATION OF REGISTRATION FEE Title of Each Class of Securities Offered Amount to be Registered(1) Maximum Offering Price Per Unit Maximum Aggregate Offering Price(1) Amount of Registration Fee(2) Common Stock, par value $0.0001 per share 4,025,000

Use these links to rapidly review the document TABLE OF CONTENTS TABLE OF CONTENTS Table of Contents Filed Pursuant to Rule 424(b)(5) Registration No.

January 21, 2021 EX-99.1

Editas Medicine Announces Pricing of Offering of Common Stock

Exhibit 99.1 Editas Medicine Announces Pricing of Offering of Common Stock CAMBRIDGE, Mass., Jan. 20, 2021 – Editas Medicine, Inc. (Nasdaq: EDIT), a leading gene editing company, today announced the pricing of an underwritten offering of 3,500,000 shares of its common stock at a public offering price of $66.00 per share, before deducting underwriter discounts and commissions and estimated offering

January 21, 2021 EX-1.1

Underwriting Agreement, dated January 20, 2021, by and among the Company, J.P. Morgan Securities LLC and Morgan Stanley & Co. LLC

Exhibit 1.1 Execution Version 3,500,000 Shares EDITAS MEDICINE, INC. COMMON STOCK, $0.0001 PAR VALUE PER SHARE UNDERWRITING AGREEMENT January 20, 2021 January 20, 2021 J.P. Morgan Securities LLC Morgan Stanley & Co. LLC As Representatives for the several Underwriters named in Schedule I hereto c/o J.P. Morgan Securities LLC 383 Madison Avenue New York, New York 10179 c/o Morgan Stanley & Co. LLC 1

January 21, 2021 8-K

Entry into a Material Definitive Agreement, Financial Statements and Exhibits, Other Events - FORM 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 20, 2021 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission

January 19, 2021 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition, Other Events - FORM 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 19, 2021 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission

January 19, 2021 EX-99.1

On December 14, 2020, the Patent Trial and Appeal Board of the USPTO (“PTAB”), declared a third interference between a pending U.S. patent application (U.S. Serial No. 14/685,510) that is owned by ToolGen and 14 U.S. patents (the 13 U.S. patents invo

Exhibit 99.1 On December 14, 2020, the Patent Trial and Appeal Board of the USPTO (“PTAB”), declared a third interference between a pending U.S. patent application (U.S. Serial No. 14/685,510) that is owned by ToolGen and 14 U.S. patents (the 13 U.S. patents involved in one of two another existing interference involving our licensor The Broad Institute (“Broad”) and U.S. Patent No. 8,889,418) and

January 19, 2021 424B5

3,500,000 Shares Common Stock

Use these links to rapidly review the document TABLE OF CONTENTS TABLE OF CONTENTS Table of Contents Filed Pursuant to Rule 424(b)(5) Registration No.

January 11, 2021 424B7

CALCULATION OF REGISTRATION FEE

Filed Pursuant to Rule 424(b)(7) Registration No. 333-223596 CALCULATION OF REGISTRATION FEE Title of each class of securities to be registered Amount to be Registered (1) Proposed Maximum Offering Price Per Share (2) Proposed Maximum Aggregate Offering Price (2) Amount of Registration Fee (3) Common Stock, $0.0001 par value per share 303,599 $71.04 $21,567,672.96 $2,353.04 (1) Pursuant to Rule 41

January 11, 2021 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits, Other Events - FORM 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 5, 2021 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission F

December 18, 2020 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers - 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 17, 2020 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission

November 6, 2020 10-Q

Quarterly Report - 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2020 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Numbe

November 6, 2020 EX-10.1

Termination Agreement, dated August 5, 2020, by and between the Registrant and Allergan Sales, LLC

Exhibit 10.1 EXECUTION VERSION Certain identified information has been excluded from this exhibit because it is both (i) not material and (ii) would likely cause competitive harm to the Company, if publicly disclosed. Double asterisks denote omissions. TERMINATION AGREEMENT This TERMINATION AGREEMENT (this “Agreement”) is entered into on August 5, 2020 (the “Effective Date”) by and between Editas

November 5, 2020 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition - 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 5, 2020 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission

November 5, 2020 EX-99.1

Editas Medicine Announces Third Quarter 2020 Results and Update EDIT-101 for LCA10 ‒ BRILLIANCE trial adult low-dose cohort completed EDIT-301 for sickle cell disease ‒ on track for IND filing by end of 2020 EDIT-201 for solid tumors ‒ preclinical da

Exhibit 99.1 Editas Medicine Announces Third Quarter 2020 Results and Update EDIT-101 for LCA10 ‒ BRILLIANCE trial adult low-dose cohort completed EDIT-301 for sickle cell disease ‒ on track for IND filing by end of 2020 EDIT-201 for solid tumors ‒ preclinical data to be presented at SITC and ASH Cash, cash equivalents, and marketable securities of $541 million as of September 30, 2020 CAMBRIDGE,

October 9, 2020 SC 13G/A

EDIT / Editas Medicine, Inc. / ARK Investment Management LLC - SC 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 SCHEDULE 13G UNDER THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No.

August 7, 2020 EX-10.2

Separation Agreement, dated as of April 30, 2020, by and between the Company and Judith Abrams.

Exhibit 10.2 11 Hurley Street Cambridge, MA 02141 P 617-401-9000 F 617-494-0985 VIA EMAIL April 30, 2020 Judith R. Abrams 102 Upper Mountain Avenue Montclair, NJ 07042 [email protected] Dear Judith: As we discussed, your employment with Editas Medicine, Inc. (the “Company”) will end effective May 1, 2020 (the “Separation Date”). As we also discussed, you will be eligible to receive the Benefi

August 7, 2020 10-Q

Quarterly Report - 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2020 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number 001

August 7, 2020 EX-10.3

Advisory Services Agreement, Dated May 1, 2020, by and between the Company and Judith Abrams

Exhibit 10.3 EDITAS MEDICINE, INC. ADVISORY SERVICE AGREEMENT This Advisory Services Agreement (the “Agreement”), is signed concurrently with the Separation Agreement dated May 1, 2020, to which this Agreement is attached as Exhibit A (the “Separation Agreement”) and effective as of May 4, 2020 (the “Effective Date”) is entered into by Editas Medicine, Inc., a Delaware corporation (the “Company”),

August 6, 2020 8-K

Entry into a Material Definitive Agreement, Termination of a Material Definitive Agreement, Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 5, 2020 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission Fi

August 6, 2020 EX-99.1

Editas Medicine Announces Second Quarter 2020 Results and Update Regained full control of ocular medicines under new agreement with AbbVie BRILLIANCE trial for EDIT-101 on track to dose at least three patients by end of 2020 Plan to file IND for EDIT

Exhibit 99.1 Editas Medicine Announces Second Quarter 2020 Results and Update Regained full control of ocular medicines under new agreement with AbbVie BRILLIANCE trial for EDIT-101 on track to dose at least three patients by end of 2020 Plan to file IND for EDIT-301 for sickle cell disease by end of 2020 Strengthened balance sheet through equity offering raising $216 million in gross proceeds Cas

June 25, 2020 EX-99.2

Editas Medicine Announces Pricing of Offering of Common Stock

Exhibit 99.2 Editas Medicine Announces Pricing of Offering of Common Stock CAMBRIDGE, Mass., June 23, 2020 – Editas Medicine, Inc. (Nasdaq: EDIT), a leading genome editing company, today announced the pricing of an underwritten offering of 6,000,000 shares of its common stock at a public offering price of $31.25 per share, before deducting underwriter discounts and commissions and estimated offeri

June 25, 2020 EX-99.1

Editas Medicine Announces Offering of Common Stock

Exhibit 99.1 Editas Medicine Announces Offering of Common Stock CAMBRIDGE, Mass., June 23, 2020 – Editas Medicine, Inc. (Nasdaq: EDIT), a leading genome editing company, today announced that it intends to offer and sell 4,000,000 shares of its common stock in an underwritten public offering. Editas Medicine intends to grant the underwriter a 30-day option to purchase up to an additional 600,000 sh

June 25, 2020 8-K

Entry into a Material Definitive Agreement, Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 23, 2020 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission Fil

June 25, 2020 EX-1.1

Underwriting Agreement, dated June 23, 2020, by and between the Company and the Underwriter

Exhibit 1.1 EXECUTION VERSION 6,000,000 Shares EDITAS MEDICINE, INC. COMMON STOCK, $0.0001 PAR VALUE PER SHARE UNDERWRITING AGREEMENT June 23, 2020 June 23, 2020 Morgan Stanley & Co. LLC As Representative for the several Underwriters named in Schedule I hereto c/o Morgan Stanley & Co. LLC 1585 Broadway New York, New York 10036 Ladies and Gentlemen: Editas Medicine, Inc., a Delaware corporation (th

June 25, 2020 424B5

CALCULATION OF REGISTRATION FEE Title of Each Class of Securities to be Registered Amount to be Registered(1) Proposed Maximum Offering Price per Share Proposed Maximum Aggregate Offering Price(1) Amount of Registration Fee(2) Common Stock, par value

Use these links to rapidly review the document TABLE OF CONTENTS Filed Pursuant to Rule 424(b)(5) Registration No.

June 23, 2020 S-3ASR

- S-3ASR

Use these links to rapidly review the document TABLE OF CONTENTS Table of Contents As filed with the Securities and Exchange Commission on June 23, 2020 Registration No.

June 15, 2020 8-K

Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 10, 2020 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission Fil

May 15, 2020 424B5

CALCULATION OF REGISTRATION FEE Title of Securities to be Registered Proposed Maximum Aggregate Offering Price Amount of Registration Fee(1) Common Stock, $0.0001 par value per share $150,000,000 $19,470

Use these links to rapidly review the document TABLE OF CONTENTS TABLE OF CONTENTS Table of Contents Filed Pursuant to Rule 424(b)(5) Registration Statement No.

May 15, 2020 8-K

Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 15, 2020 Editas Medicine, Inc. (Exact Name of Registrant as Specified in its Charter) Delaware 001-37687 46-4097528 (State or Other Jurisdiction of Incorporation) (Commission File

May 15, 2020 EX-1.1

Common Stock Sales Agreement, dated as of May 15, 2020, by and between the Company and Cowen

Exhibit 1.1 Editas Medicine, Inc. $150,000,000 COMMON STOCK SALES AGREEMENT May 15, 2020 Cowen and Company, LLC 599 Lexington Avenue New York, NY 10022 Ladies and Gentlemen: Editas Medicine, Inc., a Delaware corporation (the “Company”), confirms its agreement (this “Agreement”) with Cowen and Company, LLC (“Cowen”), as follows: 1.Issuance and Sale of Shares. The Company agrees that, from time to t

May 8, 2020 10-Q

Quarterly Report - 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2020 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number 00

Other Listings
DE:8EM 2,12 €
GB:0IFK
Fintel data has been cited in the following publications:
Daily Mail Fox Business Business Insider Wall Street Journal The Washington Post Bloomberg Financial Times Globe and Mail
NASDAQ.com Reuters The Guardian Associated Press FactCheck.org Snopes Politifact
Federal Register The Intercept Forbes Fortune Magazine TheStreet Time Magazine Canadian Broadcasting Corporation International Business Times
Cambridge University Press Investopedia MarketWatch NY Daily News Entrepreneur Newsweek Barron's El Economista