XGN / Exagen Inc. - Depositi SEC, Relazione annuale, dichiarazione di delega

Exagen Inc.
US ˙ NasdaqGM ˙ US30068X1037

Statistiche di base
LEI 549300JV2CYDOME5OO17
CIK 1274737
SEC Filings
All companies that sell securities in the United States must register with the Securities and Exchange Commission (SEC) and file reports on a regular basis. These reports include company annual reports (10K, 10Q), news updates (8K), investor presentations (found in 8Ks), insider trades (form 4), ownership reports (13D, and 13G), and reports related to the specific securities sold, such as registration statements and prospectus. This page shows recent SEC filings related to Exagen Inc.
SEC Filings (Chronological Order)
Questa pagina fornisce un elenco completo e cronologico dei depositi SEC, esclusi i documenti di proprietà che forniamo altrove.
July 29, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 29, 2025 EXAGEN INC. (Exact

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 29, 2025 EXAGEN INC. (Exact name of registrant as specified in its charter) Delaware 001-39049 20-0434866 (State or other jurisdiction of incorporation) (Commission File Number)

July 29, 2025 EX-99.1

Exagen Inc. Reports Strong Q2 2025 Results

Exagen Inc. Reports Strong Q2 2025 Results July 29, 2025 Carlsbad, Calif., – Exagen Inc. (Nasdaq: XGN), a leading provider of autoimmune testing solutions, today reported financial results for the quarter ended June 30, 2025, and recent corporate updates. Three Months Ended June 30, Six Months Ended June 30, 2025 2024 2025 2024 (Unaudited, in thousands, except ASP data) Revenue $ 17,202 $ 15,064 $

July 29, 2025 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2025 ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Commission File Number: 001-39049 EXAGEN INC. (Exact name of registrant as specif

July 17, 2025 EX-99.1

Exagen Inc. Appoints Chas McKhann to Board of Directors

Exhibit 99.1 Exagen Inc. Appoints Chas McKhann to Board of Directors Exagen Inc. (Nasdaq: XGN), a leading provider of innovative autoimmune testing solutions, announced today the appointment of Chas McKhann to its Board of Directors, effective July X, 2025. Mr. McKhann is an accomplished leader with over 25 years of experience in the life sciences industry, including Board and C-suite positions le

July 17, 2025 EX-10.1

Amended & Restated Non-Employee Director Compensation Program

Exhibit 10.1 EXAGEN INC. AMENDED AND RESTATED NON-EMPLOYEE DIRECTOR COMPENSATION PROGRAM Eligible Directors (as defined below) on the board of directors (the “Board”) of Exagen Inc. (the “Company”) shall be eligible to receive cash and equity compensation as set forth in this Amended and Restated Non-Employee Director Compensation Program (this “Program”). The cash and equity compensation describe

July 17, 2025 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 17, 2025 EXAGEN INC. (Exact name of registrant as specified in its charter) Delaware 001-39049 20-0434866 (State or other jurisdiction of incorporation) (Commission File Number)

June 30, 2025 CORRESP

EXAGEN INC. 1261 LIBERTY WAY VISTA, CA 92081

EXAGEN INC. 1261 LIBERTY WAY VISTA, CA 92081 June 30, 2025 VIA EDGAR U.S. Securities and Exchange Commission Division of Corporation Finance 100 F Street, N.E. Washington, D.C. 20549 Attention: Robert Augustin Re: Exagen Inc. Registration Statement on Form S-3 File No. 333-288199 (the “Registration Statement”) Acceleration Request Ladies and Gentlemen: In accordance with Rule 461 of Regulation C p

June 20, 2025 EX-FILING FEES

Calculation of Filing Fee Tables Form S-3 (Form Type) Exagen Inc. (Exact Name of Registrant as Specified in its Charter) Table 1: Newly Registered Securities

Exhibit 107 Calculation of Filing Fee Tables Form S-3 (Form Type) Exagen Inc. (Exact Name of Registrant as Specified in its Charter) Table 1: Newly Registered Securities Security Type Security Class Title Fee Calculation Rule Amount Registered Proposed Maximum Offering Price Per Share(2) Maximum Aggregate Offering Price Fee Rate Amount of Registration Fee Fees to Be Paid Equity Common Stock, par v

June 20, 2025 S-3

As filed with the Securities and Exchange Commission on June 20, 2025

As filed with the Securities and Exchange Commission on June 20, 2025 Registration No.

June 11, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 10, 2025 EXAGEN INC. (Exact

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 10, 2025 EXAGEN INC. (Exact name of registrant as specified in its charter) Delaware 001-39049 20-0434866 (State or other jurisdiction of incorporation) (Commission File Number)

May 20, 2025 EX-FILING FEES

Filing Fee Table.

Exhibit 107 Calculation of Filing Fee Table Form S-8 (Form Type) Exagen Inc. (Exact Name of Registrant as Specified in its Charter) Table 1: Newly Registered Security Type Security Class Title Fee Calculation Rule Amount Registered(1) Proposed Maximum Offering Price Per Unit(4) Maximum Aggregate Offering Price Fee Rate Amount of Registration Fee Equity Common Stock, par value $0.001 per share 457(

May 20, 2025 S-8

As filed with the Securities and Exchange Commission on May 20, 2025

As filed with the Securities and Exchange Commission on May 20, 2025 Registration No.

May 9, 2025 EX-99.1

Exagen Inc. Announces Closing of $20.2 Million Public Offering Including Full Exercise of Underwriter’s Option to Purchase Additional Shares

EX-99.1 Exhibit 99.1 Exagen Inc. Announces Closing of $20.2 Million Public Offering Including Full Exercise of Underwriter’s Option to Purchase Additional Shares CARLSBAD, Calif., May 9, 2025 (GLOBE NEWSWIRE) — Exagen Inc. (Nasdaq: XGN), a leading provider of autoimmune testing solutions, today announced that it has completed the sale of an additional 502,500 shares of its common stock at a public

May 9, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 8, 2025 EXAGEN INC. (Exact na

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 8, 2025 EXAGEN INC. (Exact name of registrant as specified in its charter) Commission File Number: 001-39049 Delaware 20-0434866 (State or other jurisdiction of incorporation) (IR

May 8, 2025 EX-99.2

Exagen Inc. Prices Public Offering of Common Stock

Exhibit 99.2 Exagen Inc. Prices Public Offering of Common Stock CARLSBAD, Calif., May 8, 2025 (GLOBE NEWSWIRE) — Exagen Inc. (Nasdaq: XGN), a leading provider of autoimmune testing solutions, today announced the pricing of its previously announced underwritten public offering of 3,350,000 shares of its common stock at a public offering price of $5.25 per share in the offering will be sold by Exage

May 8, 2025 424B5

3,350,000 Shares of Common Stock

424B5 Table of Contents Filed pursuant to Rule 424(b)(5) Registration No. 333-275632 PROSPECTUS SUPPLEMENT (To Prospectus dated November 29, 2023) 3,350,000 Shares of Common Stock We are offering 3,350,000 shares of our common stock. Our common stock is listed on The Nasdaq Global Market under the symbol “‘XGN.” On May 7, 2025, the last reported sale price of our common stock on The Nasdaq Global

May 8, 2025 EX-1.1

Underwriting Agreement, dated May 8, 2025, by and between Exagen Inc. and Canaccord Genuity LLC.

Exhibit 1.1 Exagen Inc. 3,350,000 Shares Common Stock Underwriting Agreement May 8, 2025 Canaccord Genuity LLC As Representative of the several Underwriters 1 Post Office Square Suite 3000 Boston, Massachusetts 02109 Ladies and Gentlemen: Exagen Inc., a Delaware corporation (the “Company”), confirms its agreement with Canaccord Genuity LLC (“Canaccord”) and each of the other Underwriters named in

May 8, 2025 8-K

Current Report

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 7, 2025 EXAGEN INC. (Exact name of registrant as specified in its charter) Delaware 001-39049 20-0434866 (State or other jurisdiction of incorporation) (Commission File Number) (I

May 8, 2025 EX-99.1

Exagen Inc. Announces Proposed Public Offering of Common Stock

EX-99.1 Exhibit 99.1 Exagen Inc. Announces Proposed Public Offering of Common Stock CARLSBAD, Calif., May 7, 2025 (GLOBE NEWSWIRE) — Exagen Inc. (Nasdaq: XGN), a leading provider of autoimmune testing solutions, today announced that it has commenced an underwritten public offering of shares of its common stock. In connection with the offering, Exagen intends to grant the underwriter a 30-day optio

May 7, 2025 424B5

SUBJECT TO COMPLETION, DATED MAY 7, 2025.

424B5 Table of Contents Filed pursuant to Rule 424(b)(5) Registration No. 333-275632 The information in this preliminary prospectus supplement is not complete and may be changed. A registration statement relating to these securities has been filed with the Securities and Exchange Commission and is effective. This preliminary prospectus supplement and the accompanying prospectus are not an offer to

May 5, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 5, 2025 EXAGEN INC. (Exact na

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 5, 2025 EXAGEN INC. (Exact name of registrant as specified in its charter) Delaware 001-39049 20-0434866 (State or other jurisdiction of incorporation) (Commission File Number) (I

May 5, 2025 EX-99.1

Exagen Inc. Reports Record Q1 2025 Revenue Driven by Growth in Average Selling Price and Testing Volume

Exagen Inc. Reports Record Q1 2025 Revenue Driven by Growth in Average Selling Price and Testing Volume May 5, 2025 Carlsbad, Calif., – Exagen Inc. (Nasdaq: XGN), a leading provider of autoimmune testing solutions, today reported financial results for the quarter ended March 31, 2025, and recent corporate updates. Three Months Ended March 31, 2025 2024 (in thousands, except ASP data) Revenue $ 15,

May 5, 2025 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2025 ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Commission File Number: 001-39049 EXAGEN INC. (Exact name of registrant as speci

April 30, 2025 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant  ☒ Filed by a Party other than the Registrant  ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule

April 30, 2025 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

DEFA14A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2))

April 28, 2025 8-K

Regulation FD Disclosure, Entry into a Material Definitive Agreement, Unregistered Sales of Equity Securities, Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 25, 2025 EXAGEN INC. (Exact name of registrant as specified in its charter) Delaware 001-39049 20-0434866 (State or other jurisdiction of incorporation) (Commission File Number)

April 28, 2025 EX-10.1

Credit Agreement and Guaranty, dated April 25, 2025, by and among the Company and Perceptive Credit Holdings IV, LP.

Exhibit 10.1 [***]: THE IDENTIFIED INFORMATION HAS BEEN OMITTED FROM THE AGREEMENT BECAUSE IT IS BOTH (i) NOT MATERIAL AND (ii) WOULD BE COMPETITIVELY HARMFUL IF PUBLICLY DISCLOSED. CREDIT AGREEMENT AND GUARANTY dated as of APRIL 25, 2025 among EXAGEN INC., as the Borrower, THE GUARANTORS FROM TIME TO TIME PARTY HERETO, as Guarantors, THE LENDERS FROM TIME TO TIME PARTY HERETO, as Lenders, AND PER

April 28, 2025 EX-4.1

Warrant Certificate, dated April 25, 2025, issued by the Company to Perceptive Credit Holdings IV, LP.

Exhibit 4.1 WARRANT CERTIFICATE THIS WARRANT CERTIFICATE AND THE SECURITIES ISSUABLE UPON EXERCISE OF THIS WARRANT CERTIFICATE HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), OR QUALIFIED UNDER ANY STATE OR FOREIGN SECURITIES LAWS AND MAY NOT BE OFFERED FOR SALE, SOLD, PLEDGED, HYPOTHECATED OR OTHERWISE TRANSFERRED OR ASSIGNED UNLESS (I) A REGISTRATION

April 28, 2025 EX-99.1

Exagen Inc. Announces Senior Secured Credit Facility with Perceptive Advisors $25 Million Funded at Close to Refinance Existing Debt and Extend Maturity Additional Borrowing Capacity Provides Minimally Dilutive Growth Capital

Exhibit 99.1 Exagen Inc. Announces Senior Secured Credit Facility with Perceptive Advisors $25 Million Funded at Close to Refinance Existing Debt and Extend Maturity Additional Borrowing Capacity Provides Minimally Dilutive Growth Capital April 28, 2025 Carlsbad, Calif., – Exagen Inc. (Nasdaq: XGN), a leading provider of autoimmune testing solutions, today announced it has entered into an agreemen

April 28, 2025 EX-10.2

Security Agreement, dated April 25, 2025, by and among the Company and Perceptive Credit Holdings IV, LP.

Exhibit 10.2 SECURITY AGREEMENT Dated as of April 25, 2025 among EXAGEN INC., as Grantor, THE OTHER GRANTORS FROM TIME TO TIME PARTY HERETO and PERCEPTIVE CREDIT HOLDINGS IV, LP, as Administrative Agent TABLE OF CONTENTS SECTION HEADING        PAGE SECTION 1. DEFINITIONS, ETC. 1 Section 1.01. Certain Uniform Commercial Code Terms 1 Section 1.02. Additional Definitions 1 Section 1.03. Other Defined

March 11, 2025 EX-19

Insider Trading Policies and Procedures.

EXAGEN INC. AMENDED AND RESTATED INSIDER TRADING COMPLIANCE POLICY This Insider Trading Compliance Policy (this “Policy”) consists of seven sections: •Section I provides an overview; •Section II sets forth the policies of Exagen Inc. prohibiting insider trading; •Section III explains insider trading; •Section IV consists of procedures that have been put in place by Exagen Inc. to prevent insider t

March 11, 2025 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One) ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2024 ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission File Number: 001-39049 EXAGEN INC. (Ex

March 11, 2025 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 11, 2025 EXAGEN INC. (Exact name of registrant as specified in its charter) Delaware 001-39049 20-0434866 (State or other jurisdiction of incorporation) (Commission File Number)

March 11, 2025 EX-99.1

Exagen Inc. Reports Strong Fourth Quarter and Full-Year 2024 Results and Business Highlights Delivered record full-year total revenue and AVISE CTD average selling price Improved full-year adjusted EBITDA loss, net loss and cash use by over 40% Comme

Exagen Inc. Reports Strong Fourth Quarter and Full-Year 2024 Results and Business Highlights Delivered record full-year total revenue and AVISE CTD average selling price Improved full-year adjusted EBITDA loss, net loss and cash use by over 40% Commercialized new biomarkers to enhance clinical utility of AVISE CTD Carlsbad, Calif., – Exagen Inc. (Nasdaq: XGN), a leading provider of autoimmune test

January 13, 2025 EX-99.1

Exagen Inc. Secures Conditional NY State Approval for New Lupus and Rheumatoid Arthritis Biomarkers and Announces Select Preliminary 2024 Financial Results New biomarkers on track for commercial launch in January 2025 Preliminary financial results in

Exagen Inc. Secures Conditional NY State Approval for New Lupus and Rheumatoid Arthritis Biomarkers and Announces Select Preliminary 2024 Financial Results New biomarkers on track for commercial launch in January 2025 Preliminary financial results indicate record full-year revenue and AVISE CTD trailing twelve-month ASP, with improvements to adjusted EBITDA and cash burn January 12, 2025 Carlsbad,

January 13, 2025 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 12, 2025 EXAGEN INC. (Exact name of registrant as specified in its charter) Delaware 001-39049 20-0434866 (State or other jurisdiction of incorporation) (Commission File Numbe

December 12, 2024 SC 13G/A

XGN / Exagen Inc. / Hunt Holdings Limited Partnership - AMENDMENT NO. 3 Passive Investment

SC 13G/A 1 eh24056697513ga3-xgn.htm AMENDMENT NO. 3 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 3)* Exagen Inc. (Name of Issuer) Common Stock, par value $0.001 per share (Title of Class of Securities) 30068X103 (CUSIP Number) December 12, 2024 (Date of Event Which Requires Filing of this Statement) Chec

November 12, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 12, 2024 EXAGEN INC. (Ex

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 12, 2024 EXAGEN INC. (Exact name of registrant as specified in its charter) Delaware 001-39049 20-0434866 (State or other jurisdiction of incorporation) (Commission File Numb

November 12, 2024 EX-99.1

Exagen Inc. Reports Third Quarter 2024 Results Expanded AVISE® CTD trailing twelve-month average selling price Reduced Adjusted EBITDA loss for first three quarters of 2024 Revenue in line with expectations, excluding one-time adjustments

Exagen Inc. Reports Third Quarter 2024 Results Expanded AVISE® CTD trailing twelve-month average selling price Reduced Adjusted EBITDA loss for first three quarters of 2024 Revenue in line with expectations, excluding one-time adjustments November 12, 2024 Carlsbad, Calif., – Exagen Inc. (Nasdaq: XGN), a leading provider of autoimmune testing solutions, today reported financial results for the qua

November 12, 2024 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2024 ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Commission File Number: 001-39049 EXAGEN INC. (Exact name of registrant as s

August 5, 2024 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 5, 2024 EXAGEN INC. (Exact name of registrant as specified in its charter) Delaware 001-39049 20-0434866 (State or other jurisdiction of incorporation) (Commission File Number)

August 5, 2024 EX-10.2

Exagen Inc. Amended and Restated Executive Change in Control and Severance Plan.

Exhibit 10.3 EXAGEN INC. AMENDED AND RESTATED EXECUTIVE CHANGE IN CONTROL AND SEVERANCE PLAN Effective as of April 25, 2022 Exagen Inc., a Delaware corporation (the “Company”), has adopted this Exagen Inc. Amended and Restated Executive Change in Control and Severance Plan, including the attached Exhibits (the “Plan”), for the benefit of Participants (as defined below) on the terms and conditions

August 5, 2024 EX-99.1

Exagen Inc. Reports Strong Second Quarter 2024 Results: Raises Guidance due to Record Performance

Exagen Inc. Reports Strong Second Quarter 2024 Results: Raises Guidance due to Record Performance August 5, 2024 Carlsbad, Calif., – Exagen Inc. (Nasdaq: XGN), a leading provider of autoimmune testing solutions, today reported financial results for the quarter ended June 30, 2024. Highlights: •Recognized record total revenue of $15.1 million in the second quarter of 2024. •Delivered gross margin o

August 5, 2024 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2024 ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Commission File Number: 001-39049 EXAGEN INC. (Exact name of registrant as specif

August 2, 2024 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 31, 2024 EXAGEN INC. (Exact name of registrant as specified in its charter) Delaware 001-39049 20-0434866 (State or other jurisdiction of incorporation) (Commission File Number)

August 2, 2024 EX-10.1

Employment Agreement, dated as of September 1, 2024, by and between the Company and Jeffrey Black.

Exhibit 10.1 EMPLOYMENT AGREEMENT This Employment Agreement (this “Agreement”) is effective as of September 1, 2024 (the “Effective Date”) by and between Exagen Inc. (the “Company”), a Delaware corporation, and Jeff Black (“Executive”). References below to the “Company” shall include its subsidiaries and affiliates when applicable. 1.Roles and Duties. Subject to the terms and conditions of this Ag

August 2, 2024 8-K/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K/A (Amendment No. 1) CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 31, 2024

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K/A (Amendment No. 1) CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 31, 2024 EXAGEN INC. (Exact name of registrant as specified in its charter) Delaware 001-39049 20-0434866 (State or other jurisdiction of incorporation) (Comm

August 2, 2024 EX-99.1

Exagen Appoints Jeffrey G. Black as New Chief Financial Officer

Exhibit 99.1 Exagen Appoints Jeffrey G. Black as New Chief Financial Officer August 1, 2024 CARLSBAD, Calif., - Exagen Inc. (Nasdaq: XGN), a leading provider of autoimmune testing solutions announced today the appointment of Jeffrey G. Black, to the role of Chief Financial Officer (CFO), effective September 1, 2024. Mr. Black replaces Kamal Adawi, who will be stepping down, and John Aballi will ac

June 11, 2024 8-K

Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 10, 2024 EXAGEN INC. (Exact name of registrant as specified in its charter) Delaware 001-39049 20-0434866 (State or other jurisdiction of incorporation) (Commission File Number)

May 13, 2024 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2024 ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Commission File Number: 001-39049 EXAGEN INC. (Exact name of registrant as speci

May 13, 2024 EX-99.1

Exagen Inc. Reports Strong First Quarter 2024 Results: Raises Guidance for Full Year

Exagen Inc. Reports Strong First Quarter 2024 Results: Raises Guidance for Full Year May 13, 2024 Carlsbad, Calif., – Exagen Inc. (Nasdaq: XGN), a leading provider of autoimmune testing solutions, today reported financial results for the quarter ended March 31, 2024. First Quarter Highlights: •Recognized total revenue of $14.4 million in the first quarter of 2024, a 28.4% increase over the first q

May 13, 2024 EX-FILING FEES

Filing Fee Table.

Exhibit 107 Calculation of Filing Fee Table Form S-8 (Form Type) Exagen Inc. (Exact Name of Registrant as Specified in its Charter) Table 1: Newly Registered Security Type Security Class Title Fee Calculation Rule Amount Registered(1) Proposed Maximum Offering Price Per Unit(4) Maximum Aggregate Offering Price Fee Rate Amount of Registration Fee Equity Common Stock, par value $0.001 per share 457(

May 13, 2024 S-8

As filed with the Securities and Exchange Commission on May 13, 2024

As filed with the Securities and Exchange Commission on May 13, 2024 Registration No.

May 13, 2024 EX-10.1

Fourth Amendment to Loan and Security Agreement dated April 12, 2024, by and among Innovatus Life Sciences Lending I, LP, other lenders and the Company.

Exhibit 10.1 Execution Version FOURTH AMENDMENT TO LOAN AND SECURITY AGREEMENT This FOURTH AMENDMENT TO LOAN AND SECURITY AGREEMENT (this “Agreement”) is entered into effective as of April 12, 2024, by and among INNOVATUS LIFE SCIENCES LENDING FUND I, LP, a Delaware limited partnership (together with its successors and assigns, “Innovatus”), as collateral agent (in such capacity, together with its

May 13, 2024 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 13, 2024 EXAGEN INC. (Exact name of registrant as specified in its charter) Delaware 001-39049 20-0434866 (State or other jurisdiction of incorporation) (Commission File Number) (

April 26, 2024 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registran

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☒ Defin

April 26, 2024 EX-99.1

Exagen Inc. Announces Changes to the Board of Directors

Exhibit 99.1 Exagen Inc. Announces Changes to the Board of Directors San Diego, Calif., April 25, 2024 (GLOBE NEWSWIRE) – Exagen Inc. (Nasdaq: XGN), a leading provider of autoimmune testing solutions, today announced changes to the Board of Directors. Exagen is pleased to announce Scott Kahn, Ph.D. is joining the Board as a Class I Director. Dr. Kahn has a distinguished career in life sciences spe

April 26, 2024 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registran

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☐ Defin

April 26, 2024 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 22, 2024 EXAGEN INC. (Exact name of registrant as specified in its charter) Delaware 001-39049 20-0434866 (State or other jurisdiction of incorporation) (Commission File Number)

March 18, 2024 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One) ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2023 ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission File Number: 001-39049 EXAGEN INC. (Ex

March 18, 2024 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 18, 2024 EXAGEN INC. (Exact name of registrant as specified in its charter) Delaware 001-39049 20-0434866 (State or other jurisdiction of incorporation) (Commission File Number)

March 18, 2024 EX-4.8

Description of Securities

Exhibit 4.8 DESCRIPTION OF SECURITIES REGISTERED PURSUANT TO SECTION 12 OF THE SECURITIES EXCHANGE ACT OF 1934 General The following description summarizes some of the terms of our capital stock. Because it is only a summary, it does not contain all the information that may be important to you and is subject to and qualified in its entirety by reference to our amended and restated certificate of i

March 18, 2024 EX-99.1

Exagen Inc. Reports Strong Fourth Quarter and Full-Year 2023 Results

Exagen Inc. Reports Strong Fourth Quarter and Full-Year 2023 Results March 18, 2024 Carlsbad, Calif., – Exagen Inc. (Nasdaq: XGN), a leading provider of autoimmune testing solutions, today reported financial results for the fourth quarter and full year ended December 31, 2023. Financial Highlights: •Record total revenue of $52.5 million for the full-year 2023, and total revenue of $13.8 million fo

February 14, 2024 SC 13G/A

XGN / Exagen Inc. / RTW INVESTMENTS, LP - EXAGEN INC. Passive Investment

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934 (Amendment No. 4)* Exagen Inc. (Name of Issuer) Common Stock, par value $0.001 per share (Title of Class of Securities) 30068X103 (CUSIP Number) December 31, 2023 (Date of event which requires filing of this statement) Check the appropriate box to designate the rule pursuant to which

February 14, 2024 SC 13G/A

XGN / Exagen Inc. / LYTTON LAURENCE W Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 2)* Exagen Inc. (Name of Issuer) Common Stock, par value $0.001 per share (Title of Class of Securities) 30068X103 (CUSIP Number) December 31, 2023 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursua

February 13, 2024 SC 13G/A

XGN / Exagen Inc. / TULLIS DICKERSON CAPITAL FOCUS III, L.P. - SC 13G/A Passive Investment

SC 13G/A 1 d748599dsc13ga.htm SC 13G/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 4)* Exagen, Inc. (Name of Issuer) Common Stock, par value $0.001 per share (Title of Class of Securities) 30068X103 (CUSIP Number) December 31, 2023 (Date of Event Which Requires Filing of this statement) Check the appr

February 13, 2024 SC 13G/A

XGN / Exagen Inc. / Stonepine Capital Management, LLC Passive Investment

SC 13G/A 1 xgn13ga2024.htm UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 3)* Exagen Inc. (Name of Issuer) Common Stock, par value $0.001 per share (Title of Class of Securities) 30068X103 (CUSIP Number) December 31, 2023 (Date of Event Which Requires Filing of this Statement) Check the appropriate box t

February 2, 2024 SC 13G/A

XGN / Exagen Inc. / Cowen Financial Products LLC - COWEN FINANCIAL PRODUCTS LLC Passive Investment

SC 13G/A 1 xgna420224.htm COWEN FINANCIAL PRODUCTS LLC UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 4)* Exagen Inc. (Name of Issuer) Common Stock (Title of Class of Securities) 30068x103 (CUSIP Number) December 29, 2023 (Date of Event which Requires Filing of this Statement) Check the appropriate box t

January 22, 2024 SC 13G/A

XGN / Exagen Inc. / NMSIC Co-Investment Fund, L.P. - SC 13G/A Passive Investment

SC 13G/A 1 ef20019398sc13ga.htm SC 13G/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 4)* Exagen Inc. (Name of Issuer) Common Stock, par value $0.001 per share (Title of Class of Securities) 30068X103 (CUSIP Number) December 31, 2023 (Date of Event Which Requires Filing of this Statement) Check the app

January 8, 2024 EX-99.1

Exagen Inc. Announces Select Preliminary Full-Year 2023 Results and Reaffirms Guidance

Exagen Inc. Announces Select Preliminary Full-Year 2023 Results and Reaffirms Guidance January 7, 2024 Carlsbad, CA – Exagen Inc. (Nasdaq: XGN), a leading provider of autoimmune testing solutions, today announces select preliminary unaudited financial results for the full year ended December 31, 2023, and reaffirms its full-year 2023 financial guidance. Select Preliminary Unaudited Financial Resul

January 8, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 7, 2024 EXAGEN INC. (Exac

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 7, 2024 EXAGEN INC. (Exact name of registrant as specified in its charter) Delaware 001-39049 20-0434866 (State or other jurisdiction of incorporation) (Commission File Number

December 11, 2023 EX-10.1

Consulting Agreement, dated as of December 6, 2023, by and between the Company and Mark Hazeltine.

Exhibit 10.1 ***THIS OFFER MUST BE ACCEPTED BY DECEMBER 10, 2023*** PROFESSIONAL SERVICES AGREEMENT This Professional Services Agreement (the “Agreement”) is effective as of December 6, 2023, by and between Exagen Inc. (the “Company”), a Delaware corporation with offices at 1261 Liberty Way, Vista, CA 92081, and John Mark Hazeltine (the “Consultant”) with a business location at . 1. Consulting Ser

December 11, 2023 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 6, 2023 EXAGEN INC. (Exact name of registrant as specified in its charter) Delaware 001-39049 20-0434866 (State or other jurisdiction of incorporation) (Commission File Numbe

November 29, 2023 424B5

PROSPECTUS SUPPLEMENT (To Prospectus Dated November 29, 2023) COMMON STOCK

Filed pursuant to Rule 424(b)(5) Registration No. 333-275632 PROSPECTUS SUPPLEMENT (To Prospectus Dated November 29, 2023) $10,223,534 COMMON STOCK On September 15, 2022, we entered into a sales agreement, as amended on November 17, 2023, or the sales agreement, with Cowen and Company LLC, or TD Cowen, relating to shares of our common stock offered by this prospectus supplement and the accompanyin

November 28, 2023 CORRESP

Exagen Inc. 1261 Liberty Way Vista, California 92081

Exagen Inc. 1261 Liberty Way Vista, California 92081 November 28, 2023 VIA EDGAR U.S. Securities and Exchange Commission Division of Corporation Finance 100 F Street, N.E. Washington, D.C. 20549 Attention: Abby Adams Re: Exagen Inc. Registration Statement on Form S-3 File No. 333-275632 (the "Registration Statement") Acceleration Request Ladies and Gentlemen: In accordance with Rule 461 of Regulat

November 27, 2023 S-3/A

As filed with the Securities and Exchange Commission on November 27, 2023

As filed with the Securities and Exchange Commission on November 27, 2023 Registration Statement No.

November 27, 2023 EX-FILING FEES

Filing Fee Table.

Exhibit 107 Calculation of Filing Fee Table Form S-3/A (Form Type) Exagen Inc. (Exact Name of Registrant as Specified in its Charter) Table 1: Newly Registered and Carryforward Securities Security Type Security Class Title Fee Calculation or Carry Forward Rule Amount Registered Proposed Maximum Offering Price Per Unit Maximum Aggregate Offering Price Fee Rate Amount of Registration Fee Carry Forwa

November 20, 2023 424B5

Up to $10,822,402 Common Stock

Filed Pursuant to Rule 424(b)(5) Registration No. 333-250015 PROSPECTUS SUPPLEMENT (To Prospectus Supplement dated September 15, 2022 and Prospectus Dated November 19, 2020) Up to $10,822,402 Common Stock This prospectus supplement amends and supplements the information in our prospectus supplement dated September 15, 2022 (the “Initial Prospectus Supplement”). This prospectus supplement should be

November 17, 2023 S-3

As filed with the Securities and Exchange Commission on November 17, 2023

As filed with the Securities and Exchange Commission on November 17, 2023 Registration Statement No.

November 17, 2023 EX-FILING FEES

Filing Fee Table.

Exhibit 107 Calculation of Filing Fee Table Form S-3 (Form Type) Exagen Inc. (Exact Name of Registrant as Specified in its Charter) Table 1: Newly Registered and Carryforward Securities Security Type Security Class Title Fee Calculation or Carry Forward Rule Amount Registered Proposed Maximum Offering Price Per Unit Maximum Aggregate Offering Price Fee Rate Amount of Registration Fee Carry Forward

November 17, 2023 EX-1.1

Amendment No. 1, dated November 17, 2023, to the Sales Agreement, dated as of September 15, 2022, by and between Exagen Inc. and Cowen and Company, LLC.

Exhibit 1.1

November 17, 2023 8-K

Entry into a Material Definitive Agreement, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 17, 2023 EXAGEN INC. (Exact name of registrant as specified in its charter) Delaware 001-39049 20-0434866 (State or other jurisdiction of incorporation) (Commission File Numb

November 13, 2023 EX-99.1

Exagen Inc. Reports Strong Third Quarter 2023 Results

Exagen Inc. Reports Strong Third Quarter 2023 Results November 13, 2023 SAN DIEGO – Exagen Inc. (Nasdaq: XGN), a leading provider of autoimmune testing solutions, today reported financial results for the quarter ended September 30, 2023. •Recognized total revenue of $13.4 million for the third quarter of 2023. •Delivered gross margin of 57.4% for the third quarter of 2023. •AVISE® CTD trailing twe

November 13, 2023 EX-10.1

Assignment and Assumption Agreement, by and among Liberty Vista, L.P., Mindera Corporation and the Company.

Exhibit 10.1

November 13, 2023 EX-10.2

Exagen Inc. Clawback Policy.

Exhibit 10.2 EXAGEN INC. CLAWBACK POLICY I.Introduction The Compensation Committee of the Board of Directors (the “Committee”) of Exagen Inc. (the “Company”) believes that it is in the best interests of the Company and its shareholders to create and maintain a culture that emphasizes integrity and accountability and that reinforces the Company’s pay-for-performance compensation philosophy. The Com

November 13, 2023 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2023 ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Commission File Number: 001-39049 EXAGEN INC. (Exact name of registrant as s

November 13, 2023 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 13, 2023 EXAGEN INC. (Exact name of registrant as specified in its charter) Delaware 001-39049 20-0434866 (State or other jurisdiction of incorporation) (Commission File Numb

October 26, 2023 8-K

Entry into a Material Definitive Agreement, Termination of a Material Definitive Agreement, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 24, 2023 EXAGEN INC. (Exact name of registrant as specified in its charter) Delaware 001-39049 20-0434866 (State or other jurisdiction of incorporation) (Commission File Numbe

August 7, 2023 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 7, 2023 EXAGEN INC. (Exact name of registrant as specified in its charter) Delaware 001-39049 20-0434866 (State or other jurisdiction of incorporation) (Commission File Number)

August 7, 2023 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2023 ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Commission File Number: 001-39049 EXAGEN INC. (Exact name of registrant as specif

August 7, 2023 EX-99.1

Exagen Inc. Reports Strong Second Quarter 2023 Results

Exagen Inc. Reports Strong Second Quarter 2023 Results August 7, 2023 SAN DIEGO – Exagen Inc. (Nasdaq: XGN), a leading provider of autoimmune testing solutions, today reported financial results for the quarter ended June 30, 2023. Second Quarter Highlights: •Delivered a record 37,749 AVISE® CTD tests in the second quarter, an 8% increase over the second quarter of 2022. •Recognized total revenue o

July 24, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 24, 2023 EXAGEN INC. (Exact

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 24, 2023 EXAGEN INC. (Exact name of registrant as specified in its charter) Delaware 001-39049 20-0434866 (State or other jurisdiction of incorporation) (Commission File Number)

July 24, 2023 EX-99.1

Exagen Inc. Appoints Paul Kim to Board of Directors

Exhibit 99.1 Exagen Inc. Appoints Paul Kim to Board of Directors July 24, 2023 at 9:00 AM EDT SAN DIEGO, July 24, 2023 (GLOBE NEWSWIRE) - Exagen Inc. (Nasdaq: XGN), a leading provider of autoimmune testing solutions, announced today that Paul Kim has been appointed as a member of the Exagen Board of Directors, effective July 24, 2023. Mr. Kim currently serves as Chief Financial Officer of Fulgent

June 14, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 9, 2023 EXAGEN INC. (Exact n

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 9, 2023 EXAGEN INC. (Exact name of registrant as specified in its charter) Delaware 001-39049 20-0434866 (State or other jurisdiction of incorporation) (Commission File Number) (

May 24, 2023 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registran

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☐ Defin

May 18, 2023 EX-FILING FEES

Filing Fee Table.

EX-FILING FEES 2 exhibit107-formsx8calculat.htm EX-107 (FILING FEES) Exhibit 107 Calculation of Filing Fee Table Form S-8 (Form Type) Exagen Inc. (Exact Name of Registrant as Specified in its Charter) Table 1: Newly Registered Security Type Security Class Title Fee Calculation Rule Amount Registered(1) Proposed Maximum Offering Price Per Unit(4) Maximum Aggregate Offering Price Fee Rate Amount of

May 18, 2023 S-8

As filed with the Securities and Exchange Commission on May 18, 2023

As filed with the Securities and Exchange Commission on May 18, 2023 Registration No.

May 15, 2023 EX-99.1

Exagen Inc. Reports First Quarter 2023 Results Record Physician Demand for AVISE® CTD

Exagen Inc. Reports First Quarter 2023 Results Record Physician Demand for AVISE® CTD May 15, 2023 SAN DIEGO – Exagen Inc. (Nasdaq: XGN)("Exagen"), a leading provider of autoimmune testing solutions, today reported financial results for the quarter ended March 31, 2023. First Quarter Highlights: •Delivered a record 37,312 AVISE® CTD tests in the first quarter, a 21% increase over the first quarter

May 15, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 15, 2023 EXAGEN INC. (Exact n

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 15, 2023 EXAGEN INC. (Exact name of registrant as specified in its charter) Delaware 001-39049 20-0434866 (State or other jurisdiction of incorporation) (Commission File Number) (

May 15, 2023 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2023 ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Commission File Number: 001-39049 EXAGEN INC. (Exact name of registrant as speci

May 4, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 28, 2023 EXAGEN INC. (Exact

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 28, 2023 EXAGEN INC. (Exact name of registrant as specified in its charter) Delaware 001-39049 20-0434866 (State or other jurisdiction of incorporation) (Commission File Number)

May 4, 2023 EX-10.1

Third Amendment to Loan and Security Agreement dated April 28, 2023, by and among Innovatus Life Sciences Lending I, LP, other lenders and the Company.

Exhibit 10.1 THIRD AMENDMENT TO LOAN AND SECURITY AGREEMENT This THIRD AMENDMENT TO LOAN AND SECURITY AGREEMENT (this “Agreement”) is entered into effective as of April 28, 2023, by and among INNOVATUS LIFE SCIENCES LENDING FUND I, LP, a Delaware limited partnership (together with its successors and assigns, “Innovatus”), as collateral agent (in such capacity, together with its successors and assi

April 28, 2023 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registran

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☐ Defin

April 28, 2023 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registran

DEF 14A 1 a2023def14aproxystatement.htm DEF 14A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission

March 23, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 20, 2023 EXAGEN INC. (Exact

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 20, 2023 EXAGEN INC. (Exact name of registrant as specified in its charter) Delaware 001-39049 20-0434866 (State or other jurisdiction of incorporation) (Commission File Number)

March 20, 2023 EX-99.1

Exagen Inc. Reports Fourth Quarter and Full Year 2022 Results Record AVISE® CTD Volume in 2022

Exagen Inc. Reports Fourth Quarter and Full Year 2022 Results Record AVISE® CTD Volume in 2022 March 20, 2023 SAN DIEGO – Exagen Inc. (Nasdaq: XGN), a leading provider of autoimmune testing solutions, today reported financial results for the fourth quarter and full year ended December 31, 2022. Recent Highlights: •Record 135,210 flagship AVISE® CTD tests, for the full year 2022, including 33,819 t

March 20, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 20, 2023 EXAGEN INC. (Exact

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 20, 2023 EXAGEN INC. (Exact name of registrant as specified in its charter) Delaware 001-39049 20-0434866 (State or other jurisdiction of incorporation) (Commission File Number)

March 20, 2023 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One) ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2022 ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission File Number: 001-39049 EXAGEN INC. (Ex

February 14, 2023 SC 13G/A

XGN / Exagen Inc / RTW INVESTMENTS, LP - EXAGEN INC. Passive Investment

SC 13G/A 1 p23-0496sc13ga.htm EXAGEN INC. SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934 (Amendment No. 3)* Exagen Inc. (Name of Issuer) Common Stock, par value $0.001 per share (Title of Class of Securities) 30068X103 (CUSIP Number) December 31, 2022 (Date of event which requires filing of this statement) Check the appropriate bo

February 13, 2023 SC 13G/A

XGN / Exagen Inc / Stonepine Capital Management, LLC Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 2)* Exagen Inc. (Name of Issuer) Common Stock, par value $0.001 per share (Title of Class of Securities) 30068X103 (CUSIP Number) December 31, 2022 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursua

February 13, 2023 SC 13G/A

XGN / Exagen Inc / LYTTON LAURENCE W Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 1)* Exagen Inc. (Name of Issuer) Common Stock, par value $0.001 per share (Title of Class of Securities) 30068X103 (CUSIP Number) December 31, 2022 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursua

February 7, 2023 EX-99.1

JOINT FILING AGREEMENT PURSUANT TO RULE 13d-1(k)

Exhibit 99.1 JOINT FILING AGREEMENT PURSUANT TO RULE 13d-1(k) The undersigned acknowledge and agree that the foregoing statement on Schedule 13G is filed on behalf of each of the undersigned and that all subsequent amendments to this statement on Schedule 13G shall be filed on behalf of each of the undersigned without the necessity of filing additional joint filing agreements. The undersigned ackn

February 7, 2023 SC 13G/A

XGN / Exagen Inc / TULLIS DICKERSON CAPITAL FOCUS III, L.P. - AMENDMENT NO. 3 TO SCHEDULE 13G Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 3)* Exagen, Inc. (Name of Issuer) Common shares, par value $0.001 per share (Title of Class of Securities) 30068X103 (CUSIP Number) December 31, 2022 (Date of Event Which Requires Filing of this statement) Check the appropriate box to designate the rule purs

February 6, 2023 SC 13G/A

XGN / Exagen Inc / BANK OF MONTREAL /CAN/ - BANK OF MONTREAL Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 1)* Exagen Inc (Name of Issuer) Common (Title of Class of Securities) 30068X103 (CUSIP Number) December 31, 2022 (Date of Event which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

February 2, 2023 SC 13G/A

XGN / Exagen Inc / NMSIC Co-Investment Fund, L.P. - SC 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 3)* Exagen Inc. (Name of Issuer) Common Stock, par value $0.001 per share (Title of Class of Securities) 30068X103 (CUSIP Number) December 31, 2022 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursua

January 23, 2023 SC 13G/A

XGN / Exagen Inc / Cowen Financial Products LLC - COWEN FINANCIAL PRODUCTS LLC Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 3)* Exagen Inc. (Name of Issuer) Common Stock (Title of Class of Securities) 30068x103 (CUSIP Number) December 30, 2022 (Date of Event which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which this Schedule is

January 23, 2023 EX-99.1

Exagen Inc. Elects Tina S. Nova, Ph.D. as Executive Chair of the Board of Directors

Exhibit 99.1 Exagen Inc. Elects Tina S. Nova, Ph.D. as Executive Chair of the Board of Directors January 23, 2023 San Diego, CA Exagen Inc. (Nasdaq: XGN), a leading provider of autoimmune testing solutions, announced today that Tina S. Nova, Ph.D. has been elected as Executive Chair of the Exagen Board of Directors, effective January 19, 2023. Dr. Nova succeeds Brian Birk, who has served as Chair

January 23, 2023 8-K

Regulation FD Disclosure, Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 23, 2023 EXAGEN INC. (Exact name of registrant as specified in its charter) Delaware 001-39049 20-0434866 (State or other jurisdiction of incorporation) (Commission File Numbe

January 23, 2023 EX-3.1

Amendment to Amended and Restated Bylaws, dated January 19, 2023

Exhibit 3.1 AMENDMENT TO THE AMENDED AND RESTATED BYLAWS OF EXAGEN INC. Pursuant to Article X of the Amended and Restated Bylaws (the “Bylaws”) of Exagen Inc. (the “Corporation”), the Bylaws are hereby amended as follows: Section 3.3 of the Bylaws is hereby amended and restated in its entirety, as follows: “3.3 ELECTION, QUALIFICATION AND TERM OF OFFICE OF DIRECTORS. Except as provided in Section

January 9, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 9, 2023 EXAGEN INC. (Exac

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 9, 2023 EXAGEN INC. (Exact name of registrant as specified in its charter) Delaware 001-39049 20-0434866 (State or other jurisdiction of incorporation) (Commission File Number

January 9, 2023 EX-99.1

Corporate Presentation

Exhibit 99.1

December 5, 2022 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits, Costs Associated with Exit or Disposal Activities

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 5, 2022 EXAGEN INC. (Exact name of registrant as specified in its charter) Delaware 001-39049 20-0434866 (State or other jurisdiction of incorporation) (Commission File Numbe

December 5, 2022 EX-10.1

Consulting Agreement, dated as of December 5, 2022, by and between the Company and Debra Zack, M.D., Ph.D.

Exhibit 10.1 Independent Contractor Agreement This Independent Contractor Agreement (?Agreement?) is made and entered into as of December 5, 2022 by and between Exagen Inc., a Delaware corporation (?Company?), and Debra Zack, MD, Ph.D., an individual (?Contractor?), with respect to the following facts: A. Company would like to engage Contractor as an independent contractor to assist with transitio

November 23, 2022 SC 13G

XGN / Exagen Inc / LYTTON LAURENCE W Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* Exagen Inc. (Name of Issuer) Common Stock, par value $0.001 per share (Title of Class of Securities) 30068X103 (CUSIP Number) November 14, 2022 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuan

November 21, 2022 10-Q/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q/A (Amendment No. 1)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q/A (Amendment No. 1) (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2022 ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Commission File Number: 001-39049 EXAGEN INC. (Exact name of

November 21, 2022 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2022 ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Commission File Number: 001-39049 EXAGEN INC. (Exact name of registrant as s

November 14, 2022 EX-99.1

Exagen Inc. Reports Third Quarter 2022 Results Medicare Reimbursement Returns

Exagen Inc. Reports Third Quarter 2022 Results Medicare Reimbursement Returns November 14, 2022 SAN DIEGO ? Exagen Inc. (Nasdaq: XGN), a leading provider of autoimmune testing solutions, today reported financial results for the quarter ended September 30, 2022. Third Quarter Highlights: ?Total revenue of $14.7 million recognized in the third quarter of 2022. Our flagship AVISE? CTD test, including

November 14, 2022 8-K

Financial Statements and Exhibits, Non-Reliance on Previously Issued Financial Statements or a Related Audit Report or Completed Interim Review, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 14, 2022 EXAGEN INC. (Exact name of registrant as specified in its charter) Delaware 001-39049 20-0434866 (State or other jurisdiction of incorporation) (Commission File Numb

November 14, 2022 NT 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 12b-25 NOTIFICATION OF LATE FILING Commission File Number: 001-39049

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 12b-25 NOTIFICATION OF LATE FILING Commission File Number: 001-39049 (Check one): ? Form 10-K ? Form 20-F ? Form 11-K ? Form 10-Q ? Form 10-D ? Form N-SAR ? Form N-CSR For Period Ended: September 30, 2022 ? Transition Report on Form 10-K ? Transition Report on Form 20-F ? Transition Report on Form 11-K ? Transition Report

October 20, 2022 EX-10.1

Employment Agreement, dated as of October 16, 2022, by and between the Company and John Aballi

EMPLOYMENT AGREEMENT This Employment Agreement (this ?Agreement?) is effective as of October 16, 2022 (the ?Effective Date?) by and between Exagen, Inc.

October 20, 2022 8-K

Regulation FD Disclosure, Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 16, 2022 EXAGEN INC. (Exact name of registrant as specified in its charter) Delaware 001-39049 20-0434866 (State or other jurisdiction of incorporation) (Commission File Numbe

October 20, 2022 EX-10.2

Severance Agreement, dated as of October 14, 2022, by and between the Company and Ron Rocca

SEVERANCE AGREEMENT October 14, 2022 BY EMAIL Fortunato Ron Rocca Dear Ron: The purpose of this Severance Agreement (the ?Severance Agreement?) is to set forth the terms of your separation from Exagen, Inc.

October 20, 2022 EX-99.1

Exagen Announces Appointment of John Aballi as CEO

Exagen Announces Appointment of John Aballi as CEO October 17, 2022 at 9:00 AM EDT SAN DIEGO, Oct.

September 15, 2022 EX-1.1

Sales Agreement, dated as of September 15, 2022, by and between the Company and Cowen and Company, LLC

EX-1.1 2 ex11-xgnxsalesagreement.htm EX-1.1 Exhibit 1.1 EXAGEN INC. $50,000,000 SALES AGREEMENT September 15, 2022 Cowen and Company, LLC 599 Lexington Avenue New York, NY 10022 Ladies and Gentlemen: Exagen Inc. (the “Company”), confirms its agreement (this “Agreement”) with Cowen and Company, LLC (“Cowen”), as follows: 1. Issuance and Sale of Shares. The Company agrees that, from time to time dur

September 15, 2022 424B5

$50,000,000 Common Stock

Filed pursuant to Rule 424(b)(5) Registration No. 333-250015 PROSPECTUS SUPPLEMENT (To Prospectus dated November 19, 2020) $50,000,000 Common Stock We have entered into a sales agreement, or the sales agreement, with Cowen and Company LLC, or Cowen, relating to shares of our common stock offered by this prospectus supplement and the accompanying prospectus. In accordance with the terms of the sale

September 15, 2022 8-K

Entry into a Material Definitive Agreement, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 15, 2022 EXAGEN INC. (Exact name of registrant as specified in its charter) Delaware 001-39049 20-0434866 (State or other jurisdiction of incorporation) (Commission File Num

August 4, 2022 EX-99.1

Exagen Inc. Reports Second Quarter 2022 Results Records in AVISE® CTD Volume, Ordering Healthcare Providers and Adopters

Exagen Inc. Reports Second Quarter 2022 Results Records in AVISE? CTD Volume, Ordering Healthcare Providers and Adopters August 4, 2022 SAN DIEGO ? Exagen Inc. (Nasdaq: XGN), a leading provider of autoimmune testing solutions, today reported financial results for the quarter ended June 30, 2022. Second Quarter Highlights: ?Recognized total revenue of $9.0 million for the second quarter of 2022. Ou

August 4, 2022 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 4, 2022 EXAGEN INC. (Exact name of registrant as specified in its charter) Delaware 001-39049 20-0434866 (State or other jurisdiction of incorporation) (Commission File Number)

August 4, 2022 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2022 ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Commission File Number: 001-39049 EXAGEN INC. (Exact name of registrant as specif

June 21, 2022 8-K

Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 16, 2022 EXAGEN INC. (Exact name of registrant as specified in its charter) Delaware 001-39049 20-0434866 (State or other jurisdiction of incorporation) (Commission File Number)

May 11, 2022 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 11, 2022 EXAGEN INC. (Exact name of registrant as specified in its charter) Delaware 001-39049 20-0434866 (State or other jurisdiction of incorporation) (Commission File Number) (

May 11, 2022 EX-10.1

Exagen Inc. Amended and Restated Executive Change in Control and Severance Plan.

Exhibit 10.1 EXAGEN INC. AMENDED AND RESTATED EXECUTIVE CHANGE IN CONTROL AND SEVERANCE PLAN Effective as of April 25, 2022 Exagen Inc., a Delaware corporation (the ?Company?), has adopted this Exagen Inc. Amended and Restated Executive Change in Control and Severance Plan, including the attached Exhibits (the ?Plan?), for the benefit of Participants (as defined below) on the terms and conditions

May 11, 2022 EX-99.1

Exagen Inc. Reports First Quarter 2022 Results Records in Ordering Healthcare Providers and Adopters, Set All-Time Record for AVISE® CTD Monthly Volume in March

Exagen Inc. Reports First Quarter 2022 Results Records in Ordering Healthcare Providers and Adopters, Set All-Time Record for AVISE? CTD Monthly Volume in March May 11, 2022 SAN DIEGO ? Exagen Inc. (Nasdaq: XGN), a leading provider of autoimmune testing solutions, today reported financial results for the quarter ended March 31, 2022. First Quarter Highlights: ?Generated total revenue of $10.4 mill

May 11, 2022 EX-FILING FEES

Filing Fee Table.

Exhibit 107 Calculation of Filing Fee Table Form S-8 (Form Type) Exagen Inc. (Exact Name of Registrant as Specified in its Charter) Table 1: Newly Registered Security Type Security Class Title Fee Calculation Rule Amount Registered(1) Proposed Maximum Offering Price Per Unit(4) Maximum Aggregate Offering Price Fee Rate Amount of Registration Fee Equity Common Stock, par value $0.001 per share 457(

May 11, 2022 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2022 ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Commission File Number: 001-39049 EXAGEN INC. (Exact name of registrant as speci

May 11, 2022 S-8

As filed with the Securities and Exchange Commission on May 11, 2022

As filed with the Securities and Exchange Commission on May 11, 2022 Registration No.

April 28, 2022 EX-10.1

Exagen Inc. Amended and Restated Executive Change in Control and Severance Plan

Exhibit 10.1 EXAGEN INC. AMENDED AND RESTATED EXECUTIVE CHANGE IN CONTROL AND SEVERANCE PLAN Effective as of April 25, 2022 Exagen Inc., a Delaware corporation (the ?Company?), has adopted this Exagen Inc. Amended and Restated Executive Change in Control and Severance Plan, including the attached Exhibits (the ?Plan?), for the benefit of Participants (as defined below) on the terms and conditions

April 28, 2022 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registran

DEF 14A 1 a2022def14a.htm DEF 14A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as perm

April 28, 2022 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registran

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ? Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ? Defin

April 28, 2022 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 25, 2022 EXAGEN INC. (Exact name of registrant as specified in its charter) Delaware 001-39049 20-0434866 (State or other jurisdiction of incorporation) (Commission File Number)

March 22, 2022 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One) ? ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2021 ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission File Number: 001-39049 EXAGEN INC. (Ex

March 22, 2022 EX-99.1

Exagen Inc. Reports Fourth Quarter and Full Year 2021 Results Six Quarterly Records: AVISE® CTD Volume, Testing Revenue, Testing Gross Margin, Testing Gross Margin Percent, Adopters, and Ordering Healthcare Providers

Exagen Inc. Reports Fourth Quarter and Full Year 2021 Results Six Quarterly Records: AVISE® CTD Volume, Testing Revenue, Testing Gross Margin, Testing Gross Margin Percent, Adopters, and Ordering Healthcare Providers March 22, 2022 SAN DIEGO – Exagen Inc. (Nasdaq: XGN), a leading provider of autoimmune testing solutions, today reported financial results for the fourth quarter and full year ended D

March 22, 2022 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 22, 2022 EXAGEN INC. (Exact name of registrant as specified in its charter) Delaware 001-39049 20-0434866 (State or other jurisdiction of incorporation) (Commission File Number)

February 15, 2022 SC 13G

XGN / Exagen Inc / BANK OF MONTREAL /CAN/ - BANK OF MONTREAL Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Exagen Inc (Name of Issuer) Common (Title of Class of Securities) 30068X103 (CUSIP Number) December 31, 2021 (Date of Event which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which this Schedule is filed: [X] Rule 13d-1(b)

February 14, 2022 SC 13G/A

XGN / Exagen Inc / RTW INVESTMENTS, LP Passive Investment

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934 (Amendment No. 2)* Exagen Inc. (Name of Issuer) Common Stock, par value $0.001 per share (Title of Class of Securities) 30068X103 (CUSIP Number) December 31, 2021 (Date of event which requires filing of this statement) Check the appropriate box to designate the rule pursuant to which

February 14, 2022 SC 13G/A

XGN / Exagen Inc / TULLIS DICKERSON CAPITAL FOCUS III, L.P. - AMENDMENT NO. 2 TO SCHEDULE 13G Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 2)* Exagen, Inc. (Name of Issuer) Common shares, par value $0.001 per share (Title of Class of Securities) 30068X103 (CUSIP Number) December 31, 2021 (Date of Event Which Requires Filing of this statement) Check the appropriate box to designate the rule purs

February 14, 2022 EX-99.1

JOINT FILING AGREEMENT PURSUANT TO RULE 13d-1(k)

Exhibit 99.1 JOINT FILING AGREEMENT PURSUANT TO RULE 13d-1(k) The undersigned acknowledge and agree that the foregoing statement on Schedule 13G is filed on behalf of each of the undersigned and that all subsequent amendments to this statement on Schedule 13G shall be filed on behalf of each of the undersigned without the necessity of filing additional joint filing agreements. The undersigned ackn

February 14, 2022 SC 13G/A

XGN / Exagen Inc / Stonepine Capital Management, LLC Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 1)* Exagen Inc. (Name of Issuer) Common Stock, par value $0.001 per share (Title of Class of Securities) 30068X103 (CUSIP Number) December 31, 2021 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursua

February 10, 2022 SC 13G/A

XGN / Exagen Inc / NMSIC Co-Investment Fund, L.P. - SC 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 2)* Exagen Inc. (Name of Issuer) Common Stock, par value $0.001 per share (Title of Class of Securities) 30068X103 (CUSIP Number) December 31, 2021 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursua

February 8, 2022 SC 13G/A

XGN / Exagen Inc / Hunt Holdings Limited Partnership - AMENDMENT NO. 2 Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No.

January 20, 2022 SC 13G/A

XGN / Exagen Inc / Cowen Financial Products LLC - COWEN FINANCIAL PRODUCTS LLC Passive Investment

SC 13G/A 1 xgna212022.htm COWEN FINANCIAL PRODUCTS LLC UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 2)* Exagen Inc. (Name of Issuer) Common Stock (Title of Class of Securities) 30068x103 (CUSIP Number) December 31, 2021 (Date of Event which Requires Filing of this Statement) Check the appropriate box t

January 19, 2022 SC 13G/A

XGN / Exagen Inc / Cowen Financial Products LLC - COWEN FINANCIAL PRODUCTS LLC Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 1)* Exagen Inc. (Name of Issuer) Common Stock (Title of Class of Securities) 30068x103 (CUSIP Number) December 31, 2021 (Date of Event which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which this Schedule is

January 10, 2022 EX-99.1

EXAGEN CONFIDENTIAL1 Rheumatoid Arthritis Drug Response This presentation contains forward-looking statements. All statements other than statements of historical facts contained in this presentation, including statements regarding our future results

EXAGEN CONFIDENTIAL1 Rheumatoid Arthritis Drug Response This presentation contains forward-looking statements.

January 10, 2022 8-K

Regulation FD Disclosure, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 10, 2022 EXAGEN INC. (Exact name of registrant as specified in its charter) Delaware 001-39049 20-0434866 (State or other jurisdiction of incorporation) (Commission File Numbe

December 27, 2021 SC 13G

XGN / Exagen Inc / Stonepine Capital Management, LLC Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* Exagen Inc. (Name of Issuer) Common Stock, par value $0.001 per share (Title of Class of Securities) 30068X103 (CUSIP Number) December 20, 2021 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuan

December 17, 2021 SC 13G

XGN / Exagen Inc / Cowen Financial Products LLC - COWEN FINANCIAL PRODUCTS LLC Passive Investment

SC 13G 1 xgn121721.htm COWEN FINANCIAL PRODUCTS LLC UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Exagen Inc. (Name of Issuer) Common Stock (Title of Class of Securities) 30068x103 (CUSIP Number) September 10, 2021 (Date of Event which Requires Filing of this Statement) Check the appropriate box to designate the rule

November 10, 2021 EX-10.3

Fifth Amendment to Standard Industrial/Commercial Multi-Tenant Lease, dated October 19, 2021, by and between RGS Properties and the Company.

Exhibit 10.3 FIFTH ADDENDUM TO STANDARD INDUSTRIAL/COMMERCIAL MULTI-TENANT LEASE - NET DATED JANUARY 13, 2012 BY AND BETWEEN RGS PROPERTIES, AS LESSOR AND EXAGEN DIAGNOSTICS, INC., AS LESSEE, FOR THE PREMISES LOCATED AT 1261 LIBERTY WAY, SUITES B & C, CALIFORNIA. Lessor and Lessee mutually agree to amend the lease as follows: Parties (1.1): Lessee has changed their name and shall here for be refer

November 10, 2021 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2021 ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Commission File Number: 001-39049 EXAGEN INC. (Exact name of registrant as s

November 10, 2021 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 10, 2021 EXAGEN INC. (Exact name of registrant as specified in its charter) Delaware 001-39049 20-0434866 (State or other jurisdiction of incorporation) (Commission File Numb

November 10, 2021 EX-10.6

Letter Agreement, dated September 28, 2021, by and between the Company and Prometheus Laboratories Inc.

Exhibit 10.6 September 28, 2021 Mr. Mike Walther Prometheus Laboratories Inc. 9410 Carroll Park Dr., Suite A San Diego, CA 92121 Dear Mr. Walther, This Letter Agreement represents the agreement between Prometheus Laboratories Inc. (?Prometheus?) and Exagen Inc. (?Exagen?) regarding the sale of certain intellectual property of Prometheus relating to methotrexate metabolites and pharmacogenetics as

November 10, 2021 EX-10.1

Sublease Agreement, dated August 19, 2021, by and between Plum Healthcare Group, LLC and the Company.

Exhibit 10.1 SUBLEASE AGREEMENT This SUBLEASE AGREEMENT (?Sublease?) is entered into as of the date of last signature below, by and between PLUM HEALTHCARE GROUP, LLC, a California limited liability company (?Sublandlord?) whose address is 2175 Salk Avenue, Carlsbad, CA 92008 and EXAGEN INC., a Delaware corporation (?Subtenant?) whose address is 1261 Liberty Way, Vista, CA 92081. RECITALS A. BROOK

November 10, 2021 EX-10.4

First Amendment to Standard Industrial/Commercial Multi-Tenant Lease, dated October 19, 2021, by and between RGS Properties and the Company.

Exhibit 10.4 FIRST ADDENDUM TO STANDARD INDUSTRIAL/COMMERCIAL MULTI-TENANT LEASE - NET DATED FEBRUARY 27, 2020 BY AND BETWEEN RGS PROPERTIES, AS LESSOR AND EXAGEN DIAGNOSTICS, INC., AS LESSEE, FOR THE PREMISES LOCATED AT 1261 LIBERTY WAY, SUITE A, CALIFORNIA. Lessor and Lessee mutually agree to amend the lease as follows: Parties (1.1): Lessee has changed their name and shall be referred to as Exa

November 10, 2021 EX-10.5

Second Amendment to Loan and Security Agreement, dated November 1, 2021, by and among Innovatus Life Sciences Lending Fund I, LP, other lenders and the Company.

Exhibit 10.5 SECOND AMENDMENT TO LOAN AND SECURITY AGREEMENT This SECOND AMENDMENT TO LOAN AND SECURITY AGREEMENT (this ?Agreement?) is entered into effective as of November 1, 2021, by and among INNOVATUS LIFE SCIENCES LENDING FUND I, LP, a Delaware limited partnership (together with its successors and assigns, ?Innovatus?), as collateral agent (in such capacity, together with its successors and

November 10, 2021 EX-10.2

Second Amendment to Standard Industrial/Commercial Single-Tenant Lease, dated October 11, 2021, by and between Liberty Vista and the Company.

Exhibit 10.2 SECOND AMENDMENT OF LEASE This Second Amendment of Lease is made on October 11, 2021, between Liberty Vista, a California limited partnership, ("Lessor"), whose address is 1000 Pioneer Way, El Cajon, CA 92020, and Exagen Diagnostics, Inc., ("Lessee"), with reference to 1221 Liberty Way, San Diego, CA 92083 who agree as follows: 1.Recitals. This Second Amendment of Lease is made with r

November 10, 2021 EX-99.1

Exagen Inc. Reports Third Quarter 2021 Results Quarterly Records: Ordering Healthcare Providers and Adopters

Exagen Inc. Reports Third Quarter 2021 Results Quarterly Records: Ordering Healthcare Providers and Adopters November 10, 2021 SAN DIEGO ? Exagen Inc. (Nasdaq: XGN), a leading provider of autoimmune testing solutions, today reported financial results for the quarter ended September 30, 2021. Third Quarter Highlights: ?Generated total revenue of $12.3 million for the third quarter of 2021, a 14% in

October 25, 2021 EX-99.1

Exagen Inc. Announces $27.2 Million Debt Refinancing

Exhibit 99.1 Exagen Inc. Announces $27.2 Million Debt Refinancing October 25, 2021 SAN DIEGO, CA ? Exagen Inc. (Nasdaq: XGN), a leading provider of autoimmune testing solutions, announced today that it entered into an amendment to its loan and security agreement with its primary lender, an affiliate of Innovatus Capital Partners, LLC (?Innovatus?). The amended agreement provides a $27.2 million, 5

October 25, 2021 8-K

Entry into a Material Definitive Agreement, Financial Statements and Exhibits, Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 21, 2021 EXAGEN INC. (Exact name of registrant as specified in its charter) Delaware 001-39049 20-0434866 (State or other jurisdiction of incorporation) (Commission File Numbe

October 19, 2021 8-K

Entry into a Material Definitive Agreement, Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 13, 2021 EXAGEN INC. (Exact name of registrant as specified in its charter) Delaware 001-39049 20-0434866 (State or other jurisdiction of incorporation) (Commission File Numbe

August 27, 2021 8-K

Entry into a Material Definitive Agreement, Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 23, 2021 EXAGEN INC. (Exact name of registrant as specified in its charter) Delaware 001-39049 20-0434866 (State or other jurisdiction of incorporation) (Commission File Number

August 9, 2021 8-K

Termination of a Material Definitive Agreement, Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 5, 2021 EXAGEN INC. (Exact name of registrant as specified in its charter) Delaware 001-39049 20-0434866 (State or other jurisdiction of incorporation) (Commission File Number)

August 9, 2021 EX-99.1

Exagen Inc. Reports Second Quarter 2021 Results Quarterly Records: Total Revenue, AVISE® CTD Revenue and Volumes, Ordering Healthcare Providers and Adopters

Exagen Inc. Reports Second Quarter 2021 Results Quarterly Records: Total Revenue, AVISE? CTD Revenue and Volumes, Ordering Healthcare Providers and Adopters August 9, 2021 SAN DIEGO ? Exagen Inc. (Nasdaq: XGN), a leading provider of autoimmune testing solutions, today reported financial results for the quarter ended June 30, 2021. Second Quarter Highlights: ?Generated record total revenue of $12.8

August 9, 2021 EX-10.1

Amendment #4 to Co-Promotion Agreement, dated June 30, 2021 by and between Janssen Biotech, Inc. and the Company.

Exhibit 10.1 CERTAIN CONFIDENTIAL INFORMATION CONTAINED IN THIS DOCUMENT, MARKED BY [***], HAS BEEN OMITTED BECAUSE EXAGEN INC. HAS DETERMINED THE INFORMATION (I) IS NOT MATERIAL AND (II) WOULD LIKELY CAUSE COMPETITIVE HARM TO EXAGEN INC. IF PUBLICLY DISCLOSED. AMENDMENT #4 TO CO-PROMOTION AGREEMENT As contemplated in the Co-Promotion Agreement between Exagen and Janssen signed December 10, 2018,

August 9, 2021 EX-4.5

Form of Exchange Warrant

Exhibit 4.5 PRE-FUNDED WARRANT TO PURCHASE COMMON STOCK EXAGEN INC. Warrant Shares: Initial Exercise Date: , 2021 Issue Date: , 2021 THIS PRE-FUNDED WARRANT TO PURCHASE COMMON STOCK (the ?Warrant?) certifies that, for value received, or its assigns (the ?Holder?) is entitled, upon the terms and subject to the limitations on exercise and the conditions hereinafter set forth, at any time on or after

August 9, 2021 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2021 ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Commission File Number: 001-39049 EXAGEN INC. (Exact name of registrant as specif

July 30, 2021 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 29, 2021 EXAGEN INC. (Exact name of registrant as specified in its charter) Delaware 001-39049 20-0434866 (State or other jurisdiction of incorporation) (Commission File Number)

July 30, 2021 EX-99.1

Exagen Appoints Ana Hooker to Board of Directors

Exagen Appoints Ana Hooker to Board of Directors July 30, 2021 SAN DIEGO ? Exagen Inc.

June 21, 2021 8-K

Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): June 17, 2021 EXAGEN INC. (Exact name of registrant as specified in its charter) Delaware 001-39049 20-0434866 (State or other jurisdiction of incorporation or organization) (Commissi

May 11, 2021 EX-99.1

Exagen Inc. Reports First Quarter 2021 Results Quarterly Records: AVISE® CTD Volumes, Ordering Healthcare Providers and Adopters

Exagen Inc. Reports First Quarter 2021 Results Quarterly Records: AVISE? CTD Volumes, Ordering Healthcare Providers and Adopters May 11, 2021 SAN DIEGO ? Exagen Inc. (Nasdaq: XGN), a leading provider of autoimmune testing solutions, today reported financial results for the quarter ended March 31, 2021. First Quarter Highlights: ?Generated total revenue of $10.6 million for the quarter ended March

May 11, 2021 S-8

- S-8

As filed with the Securities and Exchange Commission on May 11, 2021 Registration No.

May 11, 2021 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): May 11, 2021 EXAGEN INC. (Exact name of registrant as specified in its charter) Delaware 001-39049 20-0434866 (State or other jurisdiction of incorporation or organization) (Commissio

May 11, 2021 10-Q

Quarterly Report - 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2021 ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Commission File Number: 001-39049 EXAGEN INC. (Exact name of registrant as speci

April 27, 2021 DEFA14A

- DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ? Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ? Defin

April 27, 2021 DEF 14A

- DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ? Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ? Defin

April 1, 2021 10-K/A

Annual Report - 10-K/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K/A (Amendment No. 1) (Mark One) ? ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2020 ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission File Number: 001-3

March 23, 2021 EX-1.1

Underwriting Agreement, dated March 22, 2021, by and among Exagen Inc. and Cowen and Company, LLC, William Blair & Company, L.L.C. and Cantor Fitzgerald & Co., as representatives of the several underwriters named therein

Exhibit 1.1 EXAGEN INC. (a Delaware corporation) 3,700,000 Shares of Common Stock UNDERWRITING AGREEMENT Dated: March 22, 2021 3,700,000 Shares of Common Stock UNDERWRITING AGREEMENT March 22, 2021 Cowen and Company, LLC William Blair & Company, L.L.C. Cantor Fitzgerald & Co. as Representatives of the several Underwriters c/o Cowen and Company, LLC 599 Lexington Avenue New York, New York 10022 c/o

March 23, 2021 EX-99.2

Exagen Inc. Announces Pricing of Public Offering of Common Stock

Exhibit 99.2 Exagen Inc. Announces Pricing of Public Offering of Common Stock March 22, 2021 SAN DIEGO ? Exagen Inc. (Nasdaq: XGN), a leading provider of autoimmune testing solutions, today announced the pricing of an underwritten public offering of 3,700,000 shares of its common stock at a price to the public of $16.25 per share. All of the shares to be sold in the offering are to be sold by Exag

March 23, 2021 8-K

Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): March 22, 2021 EXAGEN INC. (Exact name of registrant as specified in its charter) Delaware 001-39049 20-0434866 (State or other jurisdiction of incorporation or organization) (Commiss

March 23, 2021 EX-99.1

Exagen Inc. Announces Proposed Public Offering of Common Stock

Exhibit 99.1 Exagen Inc. Announces Proposed Public Offering of Common Stock March 22, 2021 SAN DIEGO ? Exagen Inc. (Nasdaq: XGN), a leading provider of autoimmune testing solutions, today announced that it intends to offer and sell, subject to market and other conditions, shares of its common stock in an underwritten public offering. In addition, Exagen intends to grant the underwriters a 30-day o

March 23, 2021 424B5

3,700,000 Shares Common Stock

Table of Contents Filed Pursuant to Rule 424(b)(5) Registration No. 333-250015 PROSPECTUS SUPPLEMENT (To Prospectus dated November 19, 2020) 3,700,000 Shares Common Stock We are offering 3,700,000 shares of our common stock. Our common stock is listed on the Nasdaq Global Market under the symbol ?XGN.? On March 22, 2021, the last reported sales price of our common stock on the Nasdaq Global Market

March 22, 2021 8-K

Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): March 22, 2021 EXAGEN INC. (Exact name of registrant as specified in its charter) Delaware 001-39049 20-0434866 (State or other jurisdiction of incorporation or organization) (Commiss

March 22, 2021 424B5

PRELIMINARY PROSPECTUS SUPPLEMENT (Subject to Completion) Dated March 22, 2021 PRELIMINARY PROSPECTUS SUPPLEMENT (To Prospectus dated November 19, 2020) Common Stock

Table of Contents Filed Pursuant to Rule 424(b)(5) Registration No. 333-250015 The information in this preliminary prospectus supplement is not complete and may be changed. A registration statement relating to these securities has been declared effective by the Securities and Exchange Commission. This preliminary prospectus supplement and the accompanying prospectus are not an offer to sell these

March 22, 2021 EX-3.1

Amended and Restated Bylaws.

Exhibit 3.1 AMENDED AND RESTATED BYLAWS OF EXAGEN INC. (a Delaware corporation) TABLE OF CONTENTS Page ARTICLE I - CORPORATE OFFICES 1 1.1 REGISTERED OFFICE 1 1.2 OTHER OFFICES 1 ARTICLE II - MEETINGS OF STOCKHOLDERS 1 2.1 PLACE OF MEETINGS 1 2.2 ANNUAL MEETING 1 2.3 SPECIAL MEETING 1 2.4 ADVANCE NOTICE PROCEDURES FOR BUSINESS BROUGHT BEFORE A MEETING 2 2.5 ADVANCE NOTICE PROCEDURES FOR NOMINATION

March 16, 2021 EX-99.1

Exagen Inc. Reports Fourth Quarter and Full Year 2020 Results Quarterly Records: Revenue, Gross Margin, AVISE® CTD Volumes and Adopters

Exagen Inc. Reports Fourth Quarter and Full Year 2020 Results Quarterly Records: Revenue, Gross Margin, AVISE? CTD Volumes and Adopters March 16, 2021 SAN DIEGO ? Exagen Inc. (Nasdaq: XGN), a leading provider of autoimmune testing solutions, today reported financial results for the fourth quarter and full year ended December 31, 2020. Recent Highlights: ?Generated total revenue of $42.0 million fo

March 16, 2021 EX-10.34

First Amendment to Standard Industrial/Commercial Single-Tenant Lease, dated January 6, 2021, by and between Liberty Vista and the Company.

Exhibit 10.34 FIRST AMENDMENT OF LEASE This First Amendment of Lease is made on December 30, 2020, between Liberty Vista, a California limited partnership, ("Lessor"), whose address is 1000 Pioneer Way, El Cajon, CA 92020, and Exagen Diagnostics, Inc., ("Lessee"), with reference to 1221 Liberty Way, San Diego, CA 92083 who agree as follows: 1.Recitals. This First Amendment of Lease is made with re

March 16, 2021 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): March 16, 2021 EXAGEN INC. (Exact name of registrant as specified in its charter) Delaware 001-39049 20-0434866 (State or other jurisdiction of incorporation or organization) (Commiss

March 16, 2021 EX-10.46

Executive Change in Control Severance Plan.

Exhibit 10.46 EXAGEN INC. EXECUTIVE CHANGE IN CONTROL SEVERANCE PLAN Exagen Inc., a Delaware corporation (the ?Company?), has adopted this Exagen Inc. Executive Change in Control Severance Plan, including the attached Exhibits (the ?Plan?), for the benefit of Participants (as defined below) on the terms and conditions hereinafter stated. The Plan, as set forth herein, is intended to provide severa

March 16, 2021 10-K

Annual Report - 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One) ? ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2020 ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission File Number: 001-39049 EXAGEN INC. (Ex

March 16, 2021 EX-10.5

Form of Restricted Stock Unit Agreement under Exagen Inc. 2019 Incentive Award Plan.

Exhibit 10.5 EXAGEN INC. 2019 INCENTIVE AWARD PLAN RESTRICTED STOCK Unit Grant Notice Exagen Inc., a Delaware corporation (the ?Company?), has granted to the participant listed below (?Participant?) the Restricted Stock Units (the ?RSUs?) described in this Restricted Stock Unit Grant Notice (this ?Grant Notice?), subject to the terms and conditions of the Exagen Inc. 2019 Incentive Award Plan (as

March 16, 2021 EX-10.25

Amendment #3 to Co-Promotion Agreement, dated December 23, 2020 by and between Janssen Biotech, Inc. and the Company.

Exhibit 10.25 CERTAIN CONFIDENTIAL INFORMATION CONTAINED IN THIS DOCUMENT, MARKED BY [***], HAS BEEN OMITTED BECAUSE EXAGEN INC. HAS DETERMINED THE INFORMATION (I) IS NOT MATERIAL AND (II) WOULD LIKELY CAUSE COMPETITIVE HARM TO EXAGEN INC. IF PUBLICLY DISCLOSED. AMENDMENT #3 TO CO-PROMOTION AGREEMENT As contemplated in the Co-Promotion Agreement between Exagen and Janssen signed December 10, 2018,

February 24, 2021 SC 13D

United States Securities and Exchange Commission Washington, D.C. 20549 SCHEDULE 13D (Rule 13d-101) Information to be Included in Statements Filed Pursuant to § 240.13d-1(a) and Amendments Thereto Filed Pursuant to § 240.13d-2(a) Under the Securities

SC 13D United States Securities and Exchange Commission Washington, D.C. 20549 SCHEDULE 13D (Rule 13d-101) Information to be Included in Statements Filed Pursuant to § 240.13d-1(a) and Amendments Thereto Filed Pursuant to § 240.13d-2(a) Under the Securities Exchange Act of 1934 (Amendment No. )* Exagen, Inc. (Name of Issuer) Common Stock (Title of Class of Securities) 30068X103 (CUSIP Number) H.I.

February 24, 2021 EX-1

JOINT FILING AGREEMENT

Exhibit 1 JOINT FILING AGREEMENT In accordance with Rule 13d-1(k)(1) promulgated under the Securities Exchange Act of 1934, as amended, the undersigned hereby agree that they are jointly filing this statement on Schedule 13D.

February 16, 2021 SC 13G/A

SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 1 )* Exagen, Inc. (Name of Issuer) Common Stock, par value $0.001 per share (Title of Class of Securities) (CUSIP Number) December 31, 2020 (Date of Event Which Requires Filing of

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 1 )* Exagen, Inc. (Name of Issuer) Common Stock, par value $0.001 per share (Title of Class of Securities) 30068X103 (CUSIP Number) December 31, 2020 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule purs

February 16, 2021 SC 13G/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 1)*

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No.

February 12, 2021 SC 13G/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. __1__)* Exagen Inc. (Name of Issuer) Common Stock, par value $0.001 per share (Title of Class of Securities) (

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No.

February 12, 2021 EX-1

Joint Filing Statement Pursuant to Rule 13d-1(k)(1)

Exhibit 1 Joint Filing Statement Pursuant to Rule 13d-1(k)(1) The undersigned hereby consent and agree to the joint filing of Schedule 13G Amendment No.

February 11, 2021 SC 13G/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 1)*

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 1)* Exagen Inc. (Name of Issuer) Common Stock, par value $0.001 per share (Title of Class of Securities) 30068X103 (CUSIP Number) December 31, 2020 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursua

January 11, 2021 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): January 10, 2021 EXAGEN INC. (Exact name of registrant as specified in its charter) Delaware 001-39049 20-0434866 (State or other jurisdiction of incorporation or organization) (Commi

January 11, 2021 EX-99.1

Exagen Inc. Reports Preliminary Fourth Quarter 2020 Testing Results Record Testing Revenue, Adopters and AVISE CTD® Volumes

Exagen Inc. Reports Preliminary Fourth Quarter 2020 Testing Results Record Testing Revenue, Adopters and AVISE CTD® Volumes January 10, 2021 - San Diego, CA Exagen Inc. (Nasdaq: XGN), an organization dedicated to transforming the care continuum for patients suffering from autoimmune diseases, today reported preliminary, unaudited financial results for the quarter ended December 31, 2020. Testing r

December 28, 2020 8-K

Entry into a Material Definitive Agreement - 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): December 23, 2020 EXAGEN INC. (Exact name of registrant as specified in its charter) Delaware 001-39049 20-0434866 (State or other jurisdiction of incorporation or organization) (Comm

November 17, 2020 CORRESP

-

Exagen Inc. 1261 Liberty Way Vista, California 92081 November 17, 2020 VIA EDGAR U.S. Securities and Exchange Commission Division of Corporation Finance 100 F Street, N.E. Washington, D.C. 20549 Re: Exagen Inc. Registration Statement on Form S-3 File No. 333-250015 Ladies and Gentlemen: Pursuant to Rule 461 of Regulation C of the General Rules and Regulations under the Securities Act of 1933, as a

November 10, 2020 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits, Results of Operations and Financial Condition - 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): November 6, 2020 EXAGEN INC. (Exact name of registrant as specified in its charter) Delaware 001-39049 20-0434866 (State or other jurisdiction of incorporation or organization) (Commi

November 10, 2020 EX-99.1

Exagen Inc. Reports Third Quarter 2020 Results Record Adopters with 99% Stickiness and 14 Million In-Network Lives Added for AVISE® Testing

Exagen Inc. Reports Third Quarter 2020 Results Record Adopters with 99% Stickiness and 14 Million In-Network Lives Added for AVISE® Testing November 10, 2020 SAN DIEGO – Exagen Inc. (Nasdaq: XGN), an organization dedicated to transforming the care continuum for patients suffering from autoimmune diseases, today reported financial results for the quarter ended September 30, 2020. Third Quarter High

November 10, 2020 EX-10.1

Acknowledgement Letter to Loan and Security Agreement, dated October 7, 2020, by and between Innovatus Life Sciences Lending Fund I, LP and the Company.

Exhibit 10.1 EXAGEN INC. 1261 Liberty Way Vista, CA 92081 October 7, 2020 Innovatus Life Sciences Lending Fund I, LP 777 Third Avenue, 25th Floor New York, NY 10017 Attentionn: Claes Ekstrom Re: New Management Plan Ladies and Gentlemen: We refer to that certain Loan and Security Agreement, dated as of September 7, 2017 (as the same may from time to time be amended, modified, supplemented or restat

November 10, 2020 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ? ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2020 ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Commission File Number: 001-39049 EXAGEN INC. (Exact name of registrant as

November 10, 2020 S-3

As filed with the Securities and Exchange Commission on November 10, 2020

As filed with the Securities and Exchange Commission on November 10, 2020 Registration No.

November 10, 2020 EX-4.10

Form of Indenture.

Exhibit 4.10 EXAGEN INC. INDENTURE Dated as of , 20 [] Trustee TABLE OF CONTENTS Page ARTICLE I. DEFINITIONS AND INCORPORATION BY REFERENCE 1 Section 1.1. Definitions. 1 Section 1.2. Other Definitions. 4 Section 1.3. Incorporation by Reference of Trust Indenture Act. 5 Section 1.4. Rules of Construction. 5 ARTICLE II. THE SECURITIES 5 Section 2.1. Issuable in Series. 5 Section 2.2. Establishment o

September 23, 2020 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): September 21, 2020 EXAGEN INC. (Exact name of registrant as specified in its charter) Delaware 001-39049 20-0434866 (State or other jurisdiction of incorporation or organization) (Com

September 18, 2020 SC 13G

XGN / Exagen Inc. / NMSIC Co-Investment Fund, L.P. - SC 13G Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* Exagen Inc. (Name of Issuer) Common Stock, par value $0.001 per share (Title of Class of Securities) 30068X103 (CUSIP Number) September 1, 2020 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuan

July 28, 2020 EX-10.2

Amendment #2 to Co-Promotion Agreement, dated June 18, 2020, by and between Janssen Biotech, Inc. and the Registrant.

AMENDMENT #2 TO CO-PROMOTION AGREEMENT This Amendment #2 ("Amendment") is signed as of the signature date(s) below and made effective as of 18 June, 2020 ("Effective Date") by and between Janssen Biotech, Inc.

July 28, 2020 EX-99.1

Exagen Inc. Reports Second Quarter 2020 Results Testing Experiencing Monthly Sequential Improvement Record Gross Margins of 63%

Exagen Inc. Reports Second Quarter 2020 Results Testing Experiencing Monthly Sequential Improvement Record Gross Margins of 63% July 28, 2020 SAN DIEGO – Exagen Inc. (Nasdaq: XGN), an organization dedicated to transforming the care continuum for patients suffering from autoimmune diseases, today reported financial results for the quarter ended June 30, 2020. Second Quarter Highlights: •Generated t

July 28, 2020 EX-10.1

Amendment #1 to Co-Promotion Agreement, dated January 1, 2019, by and between Janssen Biotech, Inc. and the Registrant.

AMENDMENT #1 TO CO-PROMOTION AGREEMENT This Amendment #1 ("Amendment") is signed as of the signature date(s) below and made effective as of January 1, 2019 ("Effective Date") by and between Janssen Biotech, Inc.

July 28, 2020 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): July 28, 2020 EXAGEN INC. (Exact name of registrant as specified in its charter) Delaware 001-39049 20-0434866 (State or other jurisdiction of incorporation or organization) (Commissi

July 28, 2020 10-Q

Quarterly Report - 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One)  ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2020 ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Commission File Number: 001-39049 EXAGEN INC. (Exact name of registrant as spec

June 29, 2020 8-K

Entry into a Material Definitive Agreement

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): June 25, 2020 EXAGEN INC. (Exact name of registrant as specified in its charter) Delaware 001-39049 20-0434866 (State or other jurisdiction of incorporation or organization) (Commissi

June 29, 2020 8-K

Entry into a Material Definitive Agreement

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): June 25, 2020 EXAGEN INC. (Exact name of registrant as specified in its charter) Delaware 001-39049 20-0434866 (State or other jurisdiction of incorporation or organization) (Commissi

June 19, 2020 8-K

Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): June 18, 2020 EXAGEN INC. (Exact name of registrant as specified in its charter) Delaware 001-39049 20-0434866 (State or other jurisdiction of incorporation or organization) (Commissi

May 11, 2020 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): May 11, 2020 EXAGEN INC. (Exact name of registrant as specified in its charter) Delaware 001-39049 20-0434866 (State or other jurisdiction of incorporation or organization) (Commissio

May 11, 2020 10-Q

Quarterly Report - 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One)   ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2020 ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Commission File Number: 001-39049 EXAGEN INC. (Exact name of registrant as s

May 11, 2020 EX-99.1

Exagen Inc. Reports First Quarter 2020 Results AVISE® Testing Volumes Increase with Retention Rate of 99%

Exagen Inc. Reports First Quarter 2020 Results AVISE® Testing Volumes Increase with Retention Rate of 99% May 11, 2020 SAN DIEGO – Exagen Inc. (Nasdaq: XGN), an organization dedicated to transforming the care continuum for patients suffering from autoimmune diseases, today reported financial results for the quarter ended March 31, 2020. First Quarter Highlights: •Generated total revenue of $9.6 mi

April 29, 2020 DEF 14A

Schedule 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☒ Defin

April 29, 2020 DEFA14A

- DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☐ Defin

March 25, 2020 EX-99.1

Exagen Inc. Reports Fourth Quarter and Full Year 2019 Results AVISE® Testing Revenue Drives 24% Revenue Growth

Exagen Inc. Reports Fourth Quarter and Full Year 2019 Results AVISE® Testing Revenue Drives 24% Revenue Growth March 25, 2020 SAN DIEGO, CA – Exagen Inc. (Nasdaq: XGN), an organization dedicated to transforming the care continuum for patients suffering from debilitating and chronic autoimmune diseases by enabling timely differential diagnosis and optimizing therapeutic intervention, today reported

March 25, 2020 10-K

XGN / Exagen Inc. 10-K - Annual Report - 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One)   ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2019 ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission File Number: 001-39049 EXAGEN INC.

March 25, 2020 EX-10.32

Extension of Lease to Standard Industrial/Commercial Single-Tenant Lease, dated March 12, 2020, by and between Liberty Vista and the Company.

Exhibit 10.32 EXTENSION OF LEASE This Extension of Lease is made on February 25, 2020, between Liberty Vista, a California limited partnership ("Lessor"), whose address is 1000 Pioneer Way, El Cajon. CA 92020, and Exagen Diagnostics. lnc., ("Lessee"), with reference to 1221 Liberty Way, San Diego, CA 92083 who agree as follows: 1.Recitals. This Extension of Lease is made with reference to the foll

March 25, 2020 EX-10.28

Third Amendment to Standard Industrial/Commercial Multi-Tenant Lease, dated June 16, 2017, by and between RGS Properties and the Company.

Exhibit 10.28 THIRD ADDENDUM TO STANDARD INDUSTRIAL/COMMERCIAL MULTI-TENANT LEASE – NET DATED JANUARY 13, 2012 BY AND BETWEEN RGS PROPERTIES, AS LESSOR AND EXAGEN DIAGNOSTICS, INC. AS LESSEE, FOR THE PREMISES LOCATED AT 1261 LIBERTY WAY, SUITE B AND C, CALIFORNIA. Lessor and Lessee mutually agree to amend the lease as follows: Paragraph 1.3 (Term): The Lease Term will be extended to the new Expira

March 25, 2020 EX-10.31

First Amendment to Standard Industrial/Commercial Single-Tenant Lease, dated August 2, 2017, by and between Geiger Court, LLC and the Company.

Exhibit 10.31 FIRST ADDENDUM TO STANDARD INDUSTRIAL/COMMERCIAL SINGLE-TENANT LEASE – NET DATED AUGUST 15, 2014 BY AND BETWEEN GEIGER COURT, LLC, AS LESSOR AND EXAGEN DIAGNOSTICS, INC. AS LESSEE, FOR THE PREMISES LOCATED AT 1221 LIBERTY WAY, VISTA, CALIFORNIA. Lessor and Lessee mutually agree to amend the lease as follows: Paragraph 1.3 (Term): The Lease Term will be extended to the new Expiration

March 25, 2020 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): March 25, 2020 EXAGEN INC. (Exact name of registrant as specified in its charter) Delaware 001-39049 20-0434866 (State or other jurisdiction of incorporation or organization) (Commiss

March 25, 2020 EX-10.36

First Amendment to Loan and Security Agreement, dated November 19, 2019, by and between Innovatus Life Sciences Lending I, LP and the Company.

Exhibit 10.36 FIRST AMENDMENT TO LOAN AND SECURITY AGREEMENT This FIRST AMENDMENT TO LOAN AND SECURITY AGREEMENT (this “Agreement”) is entered into as of November 19, 2019, by and among INNOVATUS LIFE SCIENCES LENDING FUND I, LP, a Delaware limited partnership (together with its successors and assigns, “Innovatus”), as collateral agent (in such capacity, together with its successors and assigns in

March 25, 2020 EX-10.41

Offer Letter dated February 21, 2020, by and between Debra Zack, MD Ph.D. and the Company.

Exhibit 10.41 EXAGEN INC. February 21, 2020 Debra Zack, MD Ph.D. Dear Dr. Zack, I am pleased to confirm our offer for you to join Exagen Inc. as Chief Medical Officer with a start date of 3/24/2020. This offer is contingent upon the successful completion of a pre-employment background check and proof of work eligibility. This is an exempt position and will report to Ron Rocca. We are offering you

March 25, 2020 EX-10.33

Standard Industrial/Commercial Multi-Tenant Lease, dated March 17, 2020 by and between RGS Properties and the Company.

Exhibit 10.33 STANDARD INDUSTRIAL/COMMERCIAL MULTI-TENANT LEASE-NET 1. Basic Provisions ("Basic Provisions"). 1.1 Parties. This Lease ("Lease"), dated for reference purposes only February 27, 2020 , is made by and between RGS Properties ("Lessor") and Exagen Diagnostics, Inc ("Lessee"), (collectively the "Parties", or individually a "Party"). 1.2(a) Premises: That certain real property, including

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