Vertex Pharmaceuticals Incorporated
US ˙ NasdaqGS ˙ US92532F1003

SecurityVRTX / Vertex Pharmaceuticals Incorporated
InstitutionPineBridge Investments, L.P.
Latest Disclosed Ownership0 shares
Latest Disclosed Value $ 0
PineBridge Investments, L.P. closes position in VRTX / Vertex Pharmaceuticals Incorporated

On November 14, 2025 - PineBridge Investments, L.P. filed a 13F-HR form disclosing ownership of 0 shares of Vertex Pharmaceuticals Incorporated (US:VRTX) valued at $0 USD as of September 30, 2025. The entity filed a previous 13F-HR on August 13, 2025 disclosing 562 shares of Vertex Pharmaceuticals Incorporated. This represents a change in shares of -100.00% during the quarter. The current value of the position is $0 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2025-11-14 2025-09-30 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 0 -562 -100.00 0 -100.00
2025-08-13 2025-06-30 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 562 -13,634 -96.04 250 -96.37 0.0020
2025-05-14 2025-03-31 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 14,196 -252 -1.74 6,883 18.29 0.0547
2025-02-14 2024-12-31 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 14,448 -39,692 -73.31 5,818 -76.89 0.0438
2024-11-14 2024-09-30 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 54,140 -26,561 -32.91 25,179 -33.45 0.1889
2024-08-14 2024-06-30 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 80,701 -943 -1.16 37,834 10.86 0.3052
2024-05-14 2024-03-31 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 81,644 8,242 11.23 34,128 14.27 0.2719
2024-02-13 2023-12-31 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 73,402 -41,516 -36.13 29,866 -25.26 0.2762
2023-11-14 2023-09-30 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 114,918 -42,193 -26.86 39,962 -27.72 0.4430
2023-08-11 2023-06-30 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 157,111 -29,717 -15.91 55,289 -6.07 0.5965
2023-05-12 2023-03-31 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 186,828 23,056 14.08 58,864 24.46 0.6642
2023-02-09 2022-12-31 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 163,772 2,683 1.67 47,294 1.40 0.5727
2022-11-10 2022-09-30 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 161,089 54,590 51.26 46,642 55.42 0.6024
2022-08-05 2022-06-30 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 106,499 106,241 41,178.68 30,010 44,691.04 0.3777
2022-05-12 2022-03-31 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 258 -20,765 -98.77 67 -98.55 0.0007
2022-02-10 2021-12-31 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 21,023 -94,562 -81.81 4,617 -77.98 0.0472
2021-11-09 2021-09-30 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 115,585 5,280 4.79 20,966 -5.73 0.2510
2021-08-13 2021-06-30 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 110,305 34,483 45.48 22,241 36.51 0.2574
2021-05-14 2021-03-31 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 75,822 15,648 26.00 16,293 14.56 0.2080
2021-02-16 2020-12-31 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 60,174 3,380 5.95 14,222 -7.97 0.2187
2020-11-13 2020-09-30 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 56,794 7,249 14.63 15,454 7.45 0.2669
2020-08-13 2020-06-30 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 49,545 24,096 94.68 14,383 137.50 0.2756
2020-05-14 2020-03-31 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 25,449 25,243 12,253.88 6,056 13,357.78 0.1419
2020-02-13 2019-12-31 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 206 -2,214 -91.49 45 -89.02 0.0007
2019-11-12 2019-09-30 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 2,420 1,653 215.51 410 190.78 0.0066
2019-08-13 2019-06-30 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 767 767 141 0.0023
2019-02-13 2018-12-31 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 0 -186 -100.00 0 -100.00
2018-11-13 2018-09-30 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 186 -119 -39.02 36 -30.77 0.0007
2018-08-09 2018-06-30 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 305 -1,135 -78.82 52 -77.87 0.0013
2018-05-14 2018-03-31 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 1,440 -3,129 -68.48 235 -65.69 0.0056
2018-02-08 2017-12-31 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 4,569 4,415 2,866.88 685 2,878.26 0.0176
2017-11-13 2017-09-30 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 154 154 23 0.0006
2016-11-14 2016-09-30 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 0 -309 -100.00 0 -100.00
2016-08-09 2016-06-30 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 309 127 69.78 27 92.86 0.0014
2016-05-13 2016-03-31 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 182 17 10.30 14 -33.33 0.0007
2016-02-12 2015-12-31 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 165 165 0.00 21 0.0009
2015-08-13 2015-06-30 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 0 -89 -100.00 0 -100.00
2015-05-14 2015-03-31 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 89 -17,935 -99.51 10 -99.53 0.0004
2015-02-17 2014-12-31 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 18,024 1,189 7.06 2,142 13.27 0.0811
2015-02-24 2014-09-30 13F/A-1 VERTEX PHARMACEUTICALS INC COM COM 92532F100 16,835 -46,794 -73.54 1,891 -68.61 0.0773
2014-11-14 2014-09-30 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 16,835 1,891
2015-02-24 2014-06-30 13F/A-1 VERTEX PHARMACEUTICALS INC COM COM 92532F100 63,629 -11,280 -15.06 6,025 13.72 0.2388
2014-08-14 2014-06-30 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 63,629 6,025
2015-02-24 2014-03-31 13F/A-1 VERTEX PHARMACEUTICALS INC COM COM 92532F100 74,909 29,629 65.44 5,298 57.49 0.1746
2014-05-14 2014-03-31 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 74,909 5,298
2015-02-24 2013-12-31 13F/A-1 VERTEX PHARMACEUTICALS INC COM COM 92532F100 45,280 45,280 3,364 0.1002
2014-02-13 2013-12-31 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 45,280 3,364 0.0984
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.