HYPD / Hyperion DeFi, Inc. - Depositi SEC, Relazione annuale, dichiarazione di delega

Hyperion DeFi, Inc.
US ˙ NasdaqCM ˙ US30234E1047

Statistiche di base
CIK 1682639
SEC Filings
All companies that sell securities in the United States must register with the Securities and Exchange Commission (SEC) and file reports on a regular basis. These reports include company annual reports (10K, 10Q), news updates (8K), investor presentations (found in 8Ks), insider trades (form 4), ownership reports (13D, and 13G), and reports related to the specific securities sold, such as registration statements and prospectus. This page shows recent SEC filings related to Hyperion DeFi, Inc.
SEC Filings (Chronological Order)
Questa pagina fornisce un elenco completo e cronologico dei depositi SEC, esclusi i documenti di proprietà che forniamo altrove.
June 5, 2026 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 5, 2026 HYPERION DEFI, INC.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 5, 2026 HYPERION DEFI, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 001-38365 47-1178401 (State or other jurisdiction of incorporation) (Commission File N

May 15, 2026 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended: March 31, 2026 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to COMMISSION FILE NUMBER: 001-38365 HYPERION DEFI, INC.

May 14, 2026 EX-99.1

Hyperion DeFi Reports 1Q 2026 Financial Results with Record Net Income and Raises Guidance for Full Year 2026 Company Reports Record $8.8M Net Income and $19.5M Adjusted EBITDA(8) Treasury Exceeds 2.00M HYPE, 1.92M KNTQ, & 10.00M HPL Tokens as of May

Exhibit 99.1 Hyperion DeFi Reports 1Q 2026 Financial Results with Record Net Income and Raises Guidance for Full Year 2026 Company Reports Record $8.8M Net Income and $19.5M Adjusted EBITDA(8) Treasury Exceeds 2.00M HYPE, 1.92M KNTQ, & 10.00M HPL Tokens as of May 11(14) HYPD’s Unique “Triple-Dip” HYPE Deployment Generated >3x Base Staking Income in Q1 Company Raises Adjusted Gross Profit(1) 2026 F

May 14, 2026 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 14, 2026 HYPERION DEFI, INC.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 14, 2026 HYPERION DEFI, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 001-38365 47-1178401 (State or other jurisdiction of incorporation) (Commission File N

May 14, 2026 EX-99.2

Hyperion DeFi © 2026 1 HYPD Q1 2026 Earnings Supplement More than just HYPE. NASDAQ: HYPD Hyperion DeFi © 2026 2 Use of Non-GAAP Financial Measures This presentation includes certain non-GAAP financial measures (including on a forward-looking basis)

Exhibit 99.2 Hyperion DeFi © 2026 1 HYPD Q1 2026 Earnings Supplement More than just HYPE. NASDAQ: HYPD Hyperion DeFi © 2026 2 Use of Non-GAAP Financial Measures This presentation includes certain non-GAAP financial measures (including on a forward-looking basis) such as Adjusted Gross Profit, Gross HYPE Holdings, Net Asset Value, Operating Expenses Excluding Stock-Based Compensation, Treasury Gain

May 6, 2026 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 5, 2026 HYPERION DEFI, INC. (

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 5, 2026 HYPERION DEFI, INC. (Exact name of Registrant as Specified in Its Charter) Delaware 001-38365 47-1178401 (State or Other Jurisdiction of Incorporation) (Commission File Nu

May 6, 2026 424B5

2,777,778 shares of common stock

Filed Pursuant to Rule 424(b)(5) Registration No. 333-291570 PROSPECTUS SUPPLEMENT (To Prospectus dated December 9, 2025) 2,777,778 shares of common stock We are offering 2,777,778 shares of our common stock, $0.0001 par value per share, in this offering. Our common stock is listed on the Nasdaq Capital Market under the symbol “HYPD.” On May 4, 2026, the last reported sale price for our common sto

May 6, 2026 EX-1.1

2,777,778 Shares of Common Stock HYPERION DEFI, INC. UNDERWRITING AGREEMENT

Exhibit 1.1 2,777,778 Shares of Common Stock HYPERION DEFI, INC. UNDERWRITING AGREEMENT May 5, 2026 Chardan Capital Markets LLC One Pennsylvania Avenue, Suite 4800 New York, New York 10119 Ladies and Gentlemen: Introductory. Hyperion DeFi, Inc., a Delaware corporation (the “Company”), proposes to issue and sell to Chardan Capital Markets LLC (the “Underwriter”) an aggregate of 2,777,778 shares (th

May 6, 2026 EX-99.1

Hyperion DeFi Announces Proposed Public Offering of Common Stock and Pre-Funded Warrants

Exhibit 99.1 Hyperion DeFi Announces Proposed Public Offering of Common Stock and Pre-Funded Warrants DALLAS, TX, May 5, 2026 (GLOBE NEWSWIRE) – Hyperion DeFi, Inc. (NASDAQ: HYPD) (“Hyperion DeFi” or the “Company”), the first U.S. publicly listed DeFi company building on Hyperliquid, today announced that it intends to offer and sell, subject to market and other conditions, shares of its common sto

May 6, 2026 EX-99.2

Hyperion DeFi Announces Pricing of Public Offering of Common Stock

Exhibit 99.2 Hyperion DeFi Announces Pricing of Public Offering of Common Stock DALLAS, TX, May 6, 2026 (GLOBE NEWSWIRE) – Hyperion DeFi, Inc. (NASDAQ: HYPD) (“Hyperion DeFi” or the “Company”), the first U.S. publicly listed DeFi company building on Hyperliquid, today announced the pricing of a public offering of 2,777,778 shares of its common stock. The shares of common stock are being sold to th

May 5, 2026 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Ame

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.     ) Filed by the Registrant x Filed by a Party other than the Registrant ¨ Check the appropriate box: ¨ Preliminary Proxy Statement ¨ Con

May 5, 2026 ARS

ARS

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-K ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended: December 31, 2025 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to COMMISSION FILE NUMBER: 001-38365 HYPERION DEFI, INC.

May 5, 2026 424B5

SUBJECT TO COMPLETION, DATED MAY 5, 2026

Filed Pursuant to Rule 424(b)(5) Registration No. 333-291570 The information in this preliminary prospectus supplement and the accompanying prospectus is not complete and may be changed. A registration statement relating to the securities has been declared effective by the Securities and Exchange Commission. This preliminary prospectus supplement and the accompanying prospectus are not an offer to

May 5, 2026 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A (RULE 14a-101) SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(A) of the Securities Exchange Act of 1934

TABLE OF CONTENTS UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A (RULE 14a-101) SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(A) of the Securities Exchange Act of 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement. ☐ Confidential, for Use of the Commission Only

April 17, 2026 PRE 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A (RULE 14a-101) SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(A) of the Securities Exchange Act of 1934

TABLE OF CONTENTS UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A (RULE 14a-101) SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(A) of the Securities Exchange Act of 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☒ Preliminary Proxy Statement. ☐ Confidential, for Use of the Commission Only

March 30, 2026 EX-3.1-6

AMENDED AND RESTATED CERTIFICATE OF DESIGNATION OF PREFERENCES, RIGHTS AND LIMITATIONS HYPERION DEFI, INC. A DELAWARE CORPORATION

Exhibit 3.1.6 AMENDED AND RESTATED CERTIFICATE OF DESIGNATION OF PREFERENCES, RIGHTS AND LIMITATIONS OF HYPERION DEFI, INC. A DELAWARE CORPORATION Pursuant to Section 151 of the Delaware General Corporation Law, the undersigned, HYUNSU JUNG, hereby certifies that: 1. He is the duly elected Chief Executive Officer of HYPERION DEFI, INC., a Delaware corporation (the “Corporation”). 2. A resolution w

March 30, 2026 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-K

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-K ☒ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended: December 31, 2025 OR ☐TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to COMMISSION FILE NUMBER: 001-38365 HYPERION DEFI, INC.

March 30, 2026 EX-4.13

Hyperion DeFi, Inc. Amended and Restated Warrant To Purchase Common Stock

Exhibit 4.13 NEITHER THE ISSUANCE AND SALE OF THE SECURITIES REPRESENTED BY THIS CERTIFICATE NOR THE SECURITIES INTO WHICH THESE SECURITIES ARE EXERCISABLE HAVE BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED, OR APPLICABLE STATE SECURITIES LAWS. THE SECURITIES MAY NOT BE OFFERED FOR SALE, SOLD, TRANSFERRED OR ASSIGNED (I) IN THE ABSENCE OF (A) AN EFFECTIVE REGISTRATION STATEMENT FOR

March 30, 2026 EX-10.25

are both not material and the type of information that the registrant treats as private or confidential.] JOINT VALIDATOR OPERATORS’ AGREEMENT (For Hyperliquid Active Validator Node)

Exhibit 10.25 [Pursuant to Item 601(b)(10)(iv) of Regulation S-K, certain portions of this exhibit have been redacted. The redacted portions are both not material and the type of information that the registrant treats as private or confidential.] JOINT VALIDATOR OPERATORS’ AGREEMENT (For Hyperliquid Active Validator Node) THIS JOINT VALIDATOR OPERATORS’ AGREEMENT (including all schedules, annexes,

March 26, 2026 EX-99.2

Hyperion DeFi © 2026 1 HYPD Q4 2025 and FY 2025 Earnings Supplement More than just HYPE. NASDAQ: HYPD

Exhibit 99.2 Hyperion DeFi © 2026 1 HYPD Q4 2025 and FY 2025 Earnings Supplement More than just HYPE. NASDAQ: HYPD Hyperion DeFi © 2026 2 Use of Non - GAAP Financial Measures This presentation includes certain non - GAAP financial measures (including on a forward - looking basis) such as Adjusted Gross Profit, Gross HYPE Holdings, Net Asset Value, Operating Expenses Excluding Stock - Based Compens

March 26, 2026 EX-99.1

Hyperion DeFi Reports 4Q and FY 2025 Financial Results with Quarter-over-Quarter Growth of +64% Revenue and +87% Adjusted Gross Profit Five Diversified, Ramping DeFi Business Lines Delivered Growth Exceeding Q4 Guidance Treasury Exceeds 1.93M HYPE, 1

Exhibit 99.1 Hyperion DeFi Reports 4Q and FY 2025 Financial Results with Quarter-over-Quarter Growth of +64% Revenue and +87% Adjusted Gross Profit Five Diversified, Ramping DeFi Business Lines Delivered Growth Exceeding Q4 Guidance Treasury Exceeds 1.93M HYPE, 1.92M KNTQ, & 1.00M HPL Tokens as of March 23(14) HYPD’s Unique “Triple-Dip” HYPE Deployment Generated ~3x Base Staking Income in Q4 Annou

March 26, 2026 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 20, 2026 HYPERION DEFI, INC

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 20, 2026 HYPERION DEFI, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 001-38365 47-1178401 (State or other jurisdiction of incorporation) (Commission File

March 26, 2026 EX-3.1

THIRD AMENDED AND RESTATED HYPERION DEFI, INC. Adopted by the Board of Directors on March 20, 2026 TABLE OF CONTENTS

Exhibit 3.1 THIRD AMENDED AND RESTATED BYLAWS HYPERION DEFI, INC. Adopted by the Board of Directors on March 20, 2026 TABLE OF CONTENTS PAGE ARTICLE I - CORPORATE OFFICES 1 1.1 Registered Office 1 1.2 Other Offices 1 ARTICLE II - MEETINGS OF STOCKHOLDERS 1 2.1 Place of Meetings 1 2.2 Annual Meeting 1 2.3 Special Meeting 1 2.4 Notice of Stockholders’ Meetings 1 2.5 Manner of Giving Notice; Affidavi

January 9, 2026 424B3

Up to 50,770,667 Shares of Common Stock

Filed Pursuant to Rule 424(b)(3) Registration No. 333-288776 PROSPECTUS Up to 50,770,667 Shares of Common Stock This prospectus relates to the offer and sale from time to time, by the selling securityholders identified in this prospectus, of up to 50,770,667 shares of common stock, par value $0.0001 per share (the “Common Stock”), of Hyperion DeFi, Inc., formerly known as Eyenovia, Inc. (“Hyperion

January 5, 2026 EX-10.1

EMPLOYMENT AGREEMENT

Exhibit 10.1 EMPLOYMENT AGREEMENT This EMPLOYMENT AGREEMENT (the "Agreement") is entered into effective as of January 1, 2026 by and between Hyperion DeFi, Inc., a Delaware company (the "Company"), and Hyunsu Jung, an individual residing in Texas ("Executive"). The Company and Executive are hereinafter collectively referred to as the "Parties," and individually a "Party." 1. Position, Duties, Resp

January 5, 2026 EX-99.1

Hyperion DeFi Appoints Hyunsu Jung as Chief Executive Officer Board Confirms Leadership Team to Execute 2026 Strategic Priorities Company Also Appoints Robert Rubenstein as General Counsel

Exhibit 99.1 Hyperion DeFi Appoints Hyunsu Jung as Chief Executive Officer Board Confirms Leadership Team to Execute 2026 Strategic Priorities Company Also Appoints Robert Rubenstein as General Counsel LAGUNA HILLS, Calif., January 5, 2026 — Hyperion DeFi, Inc. (NASDAQ: HYPD) (“Hyperion DeFi” or the “Company”) today announced that its Board of Directors has appointed Hyunsu Jung as Chief Executive

January 5, 2026 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 1, 2026 HYPERION DEFI, IN

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 1, 2026 HYPERION DEFI, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 001-38365 47-1178401 (State or other jurisdiction of incorporation) (Commission Fil

December 10, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 10, 2025 HYPERION DEFI,

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 10, 2025 HYPERION DEFI, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 001-38365 47-1178401 (State or other jurisdiction of incorporation) (Commission F

December 8, 2025 CORRESP

December 8, 2025

December 8, 2025 Via EDGAR U.S. Securities and Exchange Commission Division of Corporation Finance 100 F Street, N.E. Washington, D.C. 20549 Attn: Jimmy MacNamara Re: Hyperion DeFi, Inc. (the “Company”) Registration Statement Filed on Form S-3 (the “Registration Statement”) File No. 333-291570 Ladies and Gentlemen: Pursuant to Rule 461 under the Securities Act of 1933, as amended, the Company here

December 5, 2025 S-3/A

As filed with the Securities and Exchange Commission on December 5, 2025

As filed with the Securities and Exchange Commission on December 5, 2025 Registration No: 333-288776 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.

November 17, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 14, 2025 HYPERION DEFI,

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 14, 2025 HYPERION DEFI, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 001-38365 47-1178401 (State or other jurisdiction of incorporation) (Commission F

November 17, 2025 S-3

As filed with the Securities and Exchange Commission on November 17, 2025

As filed with the Securities and Exchange Commission on November 17, 2025 Registration No: 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.

November 17, 2025 EX-1.2

HYPERION DEFI, INC. Shares of Common Stock (par value $0.0001 per share) Controlled Equity OfferingSM Sales Agreement

Exhibit 1.2 Execution Version HYPERION DEFI, INC. Shares of Common Stock (par value $0.0001 per share) Controlled Equity OfferingSM Sales Agreement November 14, 2025 Cantor Fitzgerald & Co. 499 Park Avenue New York, NY 10022 Chardan Capital Markets LLC One Pennsylvania Avenue, Suite 4800 New York, New York 10119 Ladies and Gentlemen: Hyperion DeFi, Inc. (f/k/a Eyenovia, Inc.) a Delaware corporatio

November 17, 2025 EX-FILING FEES

Security Type

Calculation of Filing Fee Tables S-3 HYPERION DEFI, INC. Table 1: Newly Registered and Carry Forward Securities ☐Not Applicable Security Type Security Class Title Fee Calculation or Carry Forward Rule Amount Registered Proposed Maximum Offering Price Per Unit Maximum Aggregate Offering Price Fee Rate Amount of Registration Fee Carry Forward Form Type Carry Forward File Number Carry Forward Initial

November 14, 2025 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended: September 30, 2025 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to COMMISSION FILE NUMBER: 001-38365 HYPERION DEFI, INC.

November 14, 2025 EX-10.3

HYPERION DEFI, INC. INDUCEMENT RESTRICTED STOCK UNIT AWARD AGREEMENT

Exhibit 10.3 HYPERION DEFI, INC. INDUCEMENT RESTRICTED STOCK UNIT AWARD AGREEMENT This Restricted Stock Unit Award Agreement (this “Agreement”) is made and entered into between Hyperion DeFi, Inc. (the “Company”) and David Knox (“Grantee”), effective as of September 29, 2025 (the “Date of Grant”). This Agreement sets forth the terms and conditions associated with the Company’s award to Grantee of

November 13, 2025 EX-99.1

Hyperion DeFi Reports Third Quarter 2025 Financial Results with Record Net Income of $6.6 Million Management Initiates Q4’25 Adjusted Revenue(3) Guidance of 31% to 43% Q-o-Q Growth Over 13 Million HYPE Tokens Staked to Hyperion’s Validator as of Octo

Exhibit 99.1 Hyperion DeFi Reports Third Quarter 2025 Financial Results with Record Net Income of $6.6 Million Management Initiates Q4’25 Adjusted Revenue(3) Guidance of 31% to 43% Q-o-Q Growth Over 13 Million HYPE Tokens Staked to Hyperion’s Validator as of October 31, 2025 Ramping Business Lines Expected to Achieve Positive Operating Cash Flows in 2026 LAGUNA HILLS, Calif., November 13, 2025 - H

November 13, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 13, 2025 HYPERION DEFI,

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 13, 2025 HYPERION DEFI, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 001-38365 47-1178401 (State or other jurisdiction of incorporation) (Commission F

November 13, 2025 EX-99.2

Hyperion DeFi © 2025 1 HYPD Q3 2025 Earnings Supplement More than just HYPE. NASDAQ: HYPD

Exhibit 99.2 Hyperion DeFi © 2025 1 HYPD Q3 2025 Earnings Supplement More than just HYPE. NASDAQ: HYPD Hyperion DeFi © 2025 2 Forward - Looking Statements; Disclaimer Except for historical information, all the statements, expectations and assumptions contained in this presentation are forwar d - l ooking statements. Forward - looking statements include, but are not limited to, statements that expr

November 12, 2025 S-8

As filed with the Securities and Exchange Commission on November 12, 2025

As filed with the Securities and Exchange Commission on November 12, 2025 Registration No.

November 12, 2025 EX-FILING FEES

Table 1: Newly Registered Securities

Calculation of Filing Fee Tables S-8 HYPERION DEFI, INC. Table 1: Newly Registered Securities Security Type Security Class Title Fee Calculation Rule Amount Registered Proposed Maximum Offering Price Per Unit Maximum Aggregate Offering Price Fee Rate Amount of Registration Fee 1 Equity Common Stock, $0.0001 par value per share Other 100,000 $ 5.73 $ 573,000.00 0.0001381 $ 79.13 Total Offering Amou

November 12, 2025 EX-4.8

HYPERION DEFI, INC. INDUCEMENT RESTRICTED STOCK UNIT AWARD AGREEMENT

Exhibit 4.8 HYPERION DEFI, INC. INDUCEMENT RESTRICTED STOCK UNIT AWARD AGREEMENT This Restricted Stock Unit Award Agreement (this “Agreement”) is made and entered into between Hyperion DeFi, Inc. (the “Company”) and David Knox (“Grantee”), effective as of September 29, 2025 (the “Date of Grant”). This Agreement sets forth the terms and conditions associated with the Company’s award to Grantee of R

October 31, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 27, 2025 HYPERION DEFI, I

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 27, 2025 HYPERION DEFI, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 001-38365 47-1178401 (State or other jurisdiction of incorporation) (Commission Fi

October 31, 2025 EX-99.1

Hyperion DeFi Announces Strategic Partnership with Felix to Launch HIP-3 Powered Perpetual Futures Market New Hyperliquid Product Compounds Yield on 500,000 HYPE Staked by the Company

Exhibit 99.1 Hyperion DeFi Announces Strategic Partnership with Felix to Launch HIP-3 Powered Perpetual Futures Market New Hyperliquid Product Compounds Yield on 500,000 HYPE Staked by the Company LAGUNA HILLS, Calif., October 29, 2025 - Hyperion DeFi, Inc. (NASDAQ: HYPD) (“Hyperion DeFi” or the “Company”), the first U.S. publicly listed company dedicated to building a long-term strategic treasury

October 2, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 30, 2025 HYPERION DEFI,

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 30, 2025 HYPERION DEFI, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 001-38365 47-1178401 (State or other jurisdiction of incorporation) (Commission

September 29, 2025 S-3/A

As filed with the Securities and Exchange Commission on September 26, 2025

As filed with the Securities and Exchange Commission on September 26, 2025 Registration No: 333-288776 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.

September 29, 2025 EX-99.1

Hyperion DeFi Announces Appointment of David Knox as Chief Financial Officer PayPal’s Former Head of Capital Markets and Head of Finance for Global Credit and Financial Services Joins Company Strong Advocate for Blockchain Adoption for Traditional In

Exhibit 99.1 Hyperion DeFi Announces Appointment of David Knox as Chief Financial Officer PayPal’s Former Head of Capital Markets and Head of Finance for Global Credit and Financial Services Joins Company Strong Advocate for Blockchain Adoption for Traditional Institutional Financial Products LAGUNA HILLS, Calif., Sept. 29, 2025 (GLOBE NEWSWIRE) - Hyperion DeFi, Inc. (NASDAQ: HYPD) (“Hyperion DeFi

September 29, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 29, 2025 HYPERION DEFI,

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 29, 2025 HYPERION DEFI, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 001-38365 47-1178401 (State or other jurisdiction of incorporation) (Commission

September 29, 2025 EX-10.1

EMPLOYMENT AGREEMENT

Exhibit 10.1 Certain information in this Exhibit was omitted by means of marking such information with brackets (“[***]”) because the identified information (i) is not material and (ii) is the type of information that the Company treats as private or confidential. EMPLOYMENT AGREEMENT This EMPLOYMENT AGREEMENT (the "Agreement') is entered as of September 8, 2025 by and between Hyperion DeFi, Inc.,

September 24, 2025 424B5

Up to $60,225,987 Common Stock

Filed Pursuant to Rule 424(b)(5) Registration No. 333-282458 PROSPECTUS SUPPLEMENT AMENDMENT NO. 1 (To prospectus supplement dated December 30, 2024 and accompanying prospectus dated October 8, 2024) Up to $60,225,987 Common Stock This prospectus supplement amendment no. 1 (the “amendment no. 1”) amends the prospectus supplement dated December 30, 2024 (the “original prospectus supplement”). This

September 24, 2025 EX-1.1

HYPERION DEFI, Inc. Shares of Common Stock ($0.0001 par value per share)

  Exhibit 1.1   HYPERION DEFI, Inc. Shares of Common Stock ($0.0001 par value per share)   AMENDMENT NO. 1 TO AMENDED AND RESTATED SALES AGREEMENT   September 24, 2025   CHARDAN CAPITAL MARKETS, LLC One Pennsylvania Avenue, Suite 4800 New York, New York 10119   Ladies and Gentlemen:   Reference is made to the Amended and Restated Sales Agreement, dated December 30, 2024 (the “Agreement”), by and b

September 24, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 24, 2025 HYPERION DEFI,

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 24, 2025 HYPERION DEFI, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 001-38365 47-1178401 (State or other jurisdiction of incorporation) (Commission

September 8, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 2, 2025 HYPERION DEFI,

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 2, 2025 HYPERION DEFI, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 001-38365 47-1178401 (State or other jurisdiction of incorporation) (Commission F

August 21, 2025 EX-3.1

CERTIFICATE OF AMENDMENT OF THIRD AMENDED AND RESTATED CERTIFICATE OF INCORPORATION OF HYPERION DEFI, INC.

Exhibit 3.1 CERTIFICATE OF AMENDMENT OF THIRD AMENDED AND RESTATED CERTIFICATE OF INCORPORATION OF HYPERION DEFI, INC. Pursuant to Section 242 of the General Corporation Law of the State of Delaware, Hyperion DeFi, Inc., a corporation organized and existing under the laws of the State of Delaware (the “Corporation”), does hereby certify as follows: 1. The name of the corporation is Hyperion DeFi,

August 21, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 18, 2025 HYPERION DEFI, IN

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 18, 2025 HYPERION DEFI, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 001-38365 47-1178401 (State or other jurisdiction of incorporation) (Commission Fil

August 18, 2025 EX-FILING FEES

Table 1: Newly Registered Securities

Calculation of Filing Fee Tables S-8 HYPERION DEFI, INC. Table 1: Newly Registered Securities Security Type Security Class Title Fee Calculation Rule Amount Registered Proposed Maximum Offering Price Per Unit Maximum Aggregate Offering Price Fee Rate Amount of Registration Fee 1 Equity Common Stock, $0.0001 par value per share Other 5,672,934 $ 6.455 $ 36,618,788.97 0.0001531 $ 5,606.34 Total Offe

August 18, 2025 S-8

As filed with the Securities and Exchange Commission on August 18, 2025

As filed with the Securities and Exchange Commission on August 18, 2025 Registration No.

August 13, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 13, 2025 HYPERION DEFI, IN

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 13, 2025 HYPERION DEFI, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 001-38365 47-1178401 (State or other jurisdiction of incorporation) (Commission Fil

August 13, 2025 EX-10.8

Amended and Restated Non-Employee Director Compensation Policy

Exhibit 10.8 Hyperion DeFi, Inc. Amended and Restated Non-Employee Director Compensation Policy Effective as of July 22, 2025 Non-employee members of the board of directors (the “Board”) of Hyperion DeFi, Inc. (the “Company”) shall receive cash and equity compensation for their service on the Board as set forth in this Non-Employee Director Compensation Policy (this “Policy”). The cash and equity

August 13, 2025 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended: June 30, 2025 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to COMMISSION FILE NUMBER: 001-38365 HYPERION DEFI, INC.

August 13, 2025 EX-99.1

Hyperion DeFi Provides Corporate Update and Reports Second Quarter 2025 Financial Results Successfully establishes cryptocurrency treasury reserve focused on the HYPE token and becomes the first publicly listed U.S. company to implement DeFi strategi

Exhibit 99.1 Hyperion DeFi Provides Corporate Update and Reports Second Quarter 2025 Financial Results Successfully establishes cryptocurrency treasury reserve focused on the HYPE token and becomes the first publicly listed U.S. company to implement DeFi strategies on Hyperliquid blockchain Accumulates more than 1.5 million HYPE to date and establishes co-branded validator with Kinetiq Reiterates

July 24, 2025 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A (RULE 14a-101) SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(A) of the Securities Exchange Act of 1934

TABLE OF CONTENTS UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A (RULE 14a-101) SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(A) of the Securities Exchange Act of 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement. ☐ Confidential, for Use of the Commission Only

July 24, 2025 ARS

ARS

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-K ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended: December 31, 2024 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to COMMISSION FILE NUMBER: 001-38365 EYENOVIA, INC.

July 18, 2025 EX-FILING FEES

Filing Fee Table

Exhibit 107 Calculation of Filing Fee Tables Form S-3 (Form Type) Hyperion DeFi, Inc.

July 18, 2025 S-3

As filed with the Securities and Exchange Commission on July 18, 2025

As filed with the Securities and Exchange Commission on July 18, 2025 Registration No: 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.

July 11, 2025 PRE 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A (RULE 14a-101) SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(A) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A (RULE 14a-101) SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(A) of the Securities Exchange Act of 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☒ Preliminary Proxy Statement. ☐ Confidential, for Use of the Commission Only (as permitted by R

July 7, 2025 424B5

Up to $23,295,524 Common Stock

Filed Pursuant to Rule 424(b)(5) Registration No. 333-282458 Prospectus Supplement (To Prospectus Supplements Dated June 27, 2025, June 2, 2025, April 17, 2025 and December 30, 2024 To Prospectus dated October 8, 2024) Up to $23,295,524 of Common Stock This prospectus supplement (“Prospectus Supplement”) amends and supplements the information in the prospectus dated October 8, 2024 (the “Prior Pro

July 2, 2025 EX-3.1

Certificate of Amendment to the Third Amended and Restated Certificate of Incorporation

Exhibit 3.1 CERTIFICATE OF AMENDMENT OF THIRD AMENDED AND RESTATED CERTIFICATE OF INCORPORATION OF EYENOVIA, INC. Pursuant to Section 242 of the General Corporation Law of the State of Delaware, Eyenovia, Inc., a corporation organized and existing under the laws of the State of Delaware (the “Corporation”), does hereby certify as follows: 1. The name of the Corporation is Eyenovia, Inc. 2. The Cor

July 2, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 30, 2025 HYPERION DEFI, INC.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 30, 2025 HYPERION DEFI, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 001-38365 47-1178401 (State or other jurisdiction of incorporation) (Commission File

July 2, 2025 EX-10.1

Separation and Release Agreement by and between the Company and Bren Kern, dated July 1, 2025

  Exhibit 10.1   Date: July 1, 2025   Bren Kern 5280 Old Midland Rd. Klamath Falls, OR 97603   Re:       Separation and Release Agreement   Dear Bren:   As we discussed, your employment with Hyperion Defi, Inc. (the “Company”) is terminated effective July 1, 2025 (the “Termination Date”). Your final paycheck will be delivered to you via direct deposit on the Termination Date.   The enclosed Separa

July 2, 2025 EX-99.1

Eyenovia Announces Rebranding and Corporate Name Change to Hyperion DeFi, Inc. Name change reflects company’s leadership position with its cryptocurrency treasury reserve strategy focused on the HYPE token Company to commence trading on Nasdaq under

Exhibit 99.1 Eyenovia Announces Rebranding and Corporate Name Change to Hyperion DeFi, Inc. Name change reflects company’s leadership position with its cryptocurrency treasury reserve strategy focused on the HYPE token Company to commence trading on Nasdaq under the symbol “HYPD” effective July 3rd Also announces official launch of the Kinetiq x Hyperion validator LAGUNA HILLS, CA, July 2, 2025 –

June 27, 2025 EX-99.1

Eyenovia Announces Co-Branded Validator with Kinetiq Kinetiq x Hyperion provides a premier liquid staking solution for institutional HYPE holders

Exhibit 99.1 Eyenovia Announces Co-Branded Validator with Kinetiq Kinetiq x Hyperion provides a premier liquid staking solution for institutional HYPE holders LAGUNA HILLS, CA, June 25, 2025 – Eyenovia, Inc. (NASDAQ: EYEN) (“Eyenovia” or the “Company”), a pioneer in ophthalmic technologies and the first publicly-listed U.S. company to build a strategic treasury of HYPE, the native token of the Hyp

June 27, 2025 8-K

Regulation FD Disclosure, Other Events, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 25, 2025 EYENOVIA, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 001-38365 47-1178401 (State or other jurisdiction of incorporation) (Commission File Numbe

June 27, 2025 424B5

Up to $14,942,887 Common Stock

Filed Pursuant to Rule 424(b)(5) Registration No. 333-282458 Prospectus Supplement (To Prospectus Supplements Dated June 2, 2025, April 17, 2025 and December 30, 2024 To Prospectus dated October 8, 2024) Up to $14,942,887 of Common Stock This prospectus supplement (“Prospectus Supplement”) amends and supplements the information in the prospectus dated October 8, 2024 (the “Prior Prospectus”), file

June 24, 2025 EX-4.2

Form of Placement Agent Warrant, dated June 17, 2025

  Exhibit 4.2   NEITHER THE ISSUANCE AND SALE OF THE SECURITIES REPRESENTED BY THIS CERTIFICATE NOR THE SECURITIES INTO WHICH THESE SECURITIES ARE EXERCISABLE HAVE BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED, OR APPLICABLE STATE SECURITIES LAWS. THE SECURITIES MAY NOT BE OFFERED FOR SALE, SOLD, TRANSFERRED OR ASSIGNED (I) IN THE ABSENCE OF (A) AN EFFECTIVE REGISTRATION STATEMENT F

June 24, 2025 EX-10.3

Fourth Amendment to Supplement to Loan and Security Agreement, dated as of June 17, 2025, by and among Eyenovia, Inc., Avenue Capital Management II, L.P., Avenue Venture Opportunities Fund, L.P. and Avenue Venture Opportunities Fund II, L.P.

Exhibit 10.3 FOURTH AMENDMENT TO SUPPLEMENT TO LOAN AND SECURITY AGREEMENT This Fourth Amendment to Supplement to Loan and Security Agreement (this “Amendment”) is entered into as of June 17, 2025, by and among AVENUE CAPITAL MANAGEMENT II, L.P., a Delaware limited partnership (as administrative and collateral agent (in such capacity, “Agent”)), AVENUE VENTURE OPPORTUNITIES FUND, L.P., a Delaware

June 24, 2025 EX-10.4

Executive Employment Agreement by and between Eyenovia, Inc. and Hyunsu Jung, dated June 17, 2025

Exhibit 10.4 Certain information in this Exhibit was omitted by means of marking such information with brackets (“[***]”) because the identified information (i) is not material and (ii) is the type of information that the Company treats as private or confidential. EMPLOYMENT AGREEMENT This EMPLOYMENT AGREEMENT (the "Agreement') is entered as of June 17, 2025 by and between Eyenovia, Inc., a Delawa

June 24, 2025 EX-99.1

Announces private placement EYEN to become first U.S.-based publicly listed company to hold HYPE in its treasury Hyunsu Jung appointed Chief Investment Officer and Board Member

Exhibit 99.1 Eyenovia Announces $50 Million Investment to Launch a Hyperliquid (HYPE token) Cryptocurrency Treasury Reserve Strategy June 17, 2025 at 2:55 PM EDT Announces private placement EYEN to become first U.S.-based publicly listed company to hold HYPE in its treasury Hyunsu Jung appointed Chief Investment Officer and Board Member LAGUNA HILLS, Calif., June 17, 2025 (GLOBE NEWSWIRE) - Eyenov

June 24, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 17, 2025 EYENOVIA, INC. (Exa

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 17, 2025 EYENOVIA, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 001-38365 47-1178401 (State or other jurisdiction of incorporation) (Commission File Numbe

June 24, 2025 EX-4.3

Form of Lender Warrant, dated June 17, 2025

Exhibit 4.3 NEITHER THIS SECURITY NOR THE SECURITIES FOR WHICH THIS SECURITY IS EXERCISABLE HAVE BEEN REGISTERED WITH THE SECURITIES AND EXCHANGE COMMISSION OR THE SECURITIES COMMISSION OF ANY STATE IN RELIANCE UPON AN EXEMPTION FROM REGISTRATION UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), AND, ACCORDINGLY, MAY NOT BE OFFERED OR SOLD EXCEPT PURSUANT TO AN EFFECTIVE REGISTR

June 24, 2025 EX-10.5

Amended and Restated Employment Agreement by and between Eyenovia, Inc. and Michael Rowe, dated as of June 17, 2025

Exhibit 10.5 Certain information in this Exhibit was omitted by means of marking such information with brackets (“[***]”) because the identified information (i) is not material and (ii) is the type of information that the Company treats as private or confidential. AMENDED AND RESTATED EMPLOYMENT AGREEMENT This AMENDED AND RESTATED EMPLOYMENT AGREEMENT (the "Agreement') is entered into effective as

June 24, 2025 EX-4.1

Form of Purchaser Warrant, dated June 17, 2025

  Exhibit 4.1   NEITHER THE ISSUANCE AND SALE OF THE SECURITIES REPRESENTED BY THIS CERTIFICATE NOR THE SECURITIES INTO WHICH THESE SECURITIES ARE EXERCISABLE HAVE BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED, OR APPLICABLE STATE SECURITIES LAWS. THE SECURITIES MAY NOT BE OFFERED FOR SALE, SOLD, TRANSFERRED OR ASSIGNED (I) IN THE ABSENCE OF (A) AN EFFECTIVE REGISTRATION STATEMENT F

June 24, 2025 EX-10.2

Form of Registration Rights Agreement, dated June 17, 2025

  Exhibit 10.2   REGISTRATION RIGHTS AGREEMENT   This REGISTRATION RIGHTS AGREEMENT (this “Agreement”), dated as of June 17, 2025, is by and among Eyenovia, Inc., a Delaware corporation (the “Company”), and each investor signatory hereto (each, a “Holder” and collectively, together with its respective permitted assigns, the “Holders”).   RECITALS   A. In connection with the Securities Purchase Agr

June 24, 2025 EX-3.1

Certificate of Designation of Series A Non-Voting Convertible Preferred Stock

Exhibit 3.1 Eyenovia, Inc. CERTIFICATE OF DESIGNATION OF PREFERENCES, RIGHTS AND LIMITATIONS OF SERIES a NON-VOTING CONVERTIBLE PREFERRED STOCK Pursuant to Section 151 of the General Corporation Law of the State of Delaware THE UNDERSIGNED DOES HEREBY CERTIFY, on behalf of Eyenovia, Inc., a Delaware corporation (the “Corporation”), that the following resolution was duly adopted by the Board of Dir

June 24, 2025 EX-99.2

EYEN to bring on major Hyperliquid Thought Leader to support HYPE Treasury Strategy

Exhibit 99.2 Eyenovia Announces Appointment of a Strategic Advisor for Digital Asset Treasury Strategy and Amendment of Debt Agreement with Avenue Capital Group June 18, 2025 at 8:32 AM EDT EYEN to bring on major Hyperliquid Thought Leader to support HYPE Treasury Strategy LAGUNA HILLS, Calif., June 18, 2025 (GLOBE NEWSWIRE) - Eyenovia, Inc. (NASDAQ: EYEN) (“Eyenovia” or the “Company”), a pioneer

June 24, 2025 EX-10.1

Form of Securities Purchase Agreement, dated June 17, 2025

Exhibit 10.1 SECURITIES PURCHASE AGREEMENT This SECURITIES PURCHASE AGREEMENT (the “Agreement”), dated as of June 17, 2025, is by and between Eyenovia, Inc., a Delaware corporation (the “Company”), and each investor identified in the signature pages hereto (each, including its successors and assigns, an “Investor” and together the “Investors” and, together with the Company, the “Parties” and each

June 5, 2025 EX-10.1

Third Amendment to Supplement to Loan and Security Agreement, dated as of May 30, 2025, by and among Eyenovia, Inc., Avenue Capital Management II, L.P., Avenue Venture Opportunities Fund, L.P. and Avenue Venture Opportunities Fund II, L.P.

Exhibit 10.1 THIRD AMENDMENT TO SUPPLEMENT TO LOAN AND SECURITY AGREEMENT This Third Amendment to Supplement to Loan and Security Agreement (this “Amendment”) is entered into as of May 30, 2025, by and among AVENUE CAPITAL MANAGEMENT II, L.P., a Delaware limited partnership (as administrative and collateral agent (in such capacity, “Agent”)), AVENUE VENTURE OPPORTUNITIES FUND, L.P., a Delaware lim

June 5, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 30, 2025 EYENOVIA, INC. (Exac

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 30, 2025 EYENOVIA, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 001-38365 47-1178401 (State or other jurisdiction of incorporation) (Commission File Number

June 2, 2025 424B5

Up to $857,500 Common Stock

Filed Pursuant to Rule 424(b)(5) Registration No. 333-282458 Prospectus Supplement (To Prospectus Supplements Dated April 17, 2025 and December 30, 2024 To Prospectus dated October 8, 2024) Up to $857,500 of Common Stock This prospectus supplement (“Prospectus Supplement”) amends and supplements the information in the prospectus, dated October 8, 2024 (the “Prior Prospectus”), filed with the Secur

May 19, 2025 8-K

Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 19, 2025 EYENOVIA, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 001-38365 47-1178401 (State or other jurisdiction of incorporation) (Commission File Number

May 19, 2025 EX-99.1

Eyenovia Provides Updates on Potential Merger with Betaliq and Development of the Optejet User Filled Device (UFD), and Reports First Quarter 2025 Financial Results Eyenovia and Betaliq continue to negotiate a binding merger agreement consistent with

Exhibit 99.1 Eyenovia Provides Updates on Potential Merger with Betaliq and Development of the Optejet User Filled Device (UFD), and Reports First Quarter 2025 Financial Results Eyenovia and Betaliq continue to negotiate a binding merger agreement consistent with the previously announced signed Letter of Intent Reports continued progress on the development of the user-filled Optejet, and remains o

May 19, 2025 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended: March 31, 2025 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to COMMISSION FILE NUMBER: 001-38365 EYENOVIA, INC.

May 15, 2025 NT 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 12b-25 NOTIFICATION OF LATE FILING

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 12b-25 NOTIFICATION OF LATE FILING (Check one): ¨ Form 10-K ¨ Form 20-F ¨ Form 11-K x Form 10-Q ¨ Form 10-D ¨ Form N-CEN ¨ Form N-CSR For Period Ended: March 31, 2025 ¨ Transition Report on Form 10-K ¨ Transition Report on Form 20-F ¨ Transition Report on Form 11-K ¨ Transition Report on Form 10-Q For the Transition Perio

May 2, 2025 EX-16.1

Letter from Marcum LLP, dated May 2, 2025, addressed to the Securities and Exchange Commission

Exhibit 16.1 May 2, 2025 Securities and Exchange Commission 100 F Street, N.E. Washington, DC 20549 Commissioners: We have read the statements made by Eyenovia, Inc. under Item 4.01 of its Form 8-K dated May 2, 2025. We agree with the statements concerning our Firm in such Form 8-K; we are not in a position to agree or disagree with other statements of Eyenovia, Inc. contained therein. Very truly

May 2, 2025 8-K

Changes in Registrant's Certifying Accountant

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 2, 2025 EYENOVIA, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 001-38365 47-1178401 (State or other jurisdiction of incorporation) (Commission File Number)

May 2, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 29, 2025 EYENOVIA, INC. (Ex

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 29, 2025 EYENOVIA, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 001-38365 47-1178401 (State or other jurisdiction of incorporation) (Commission File Numb

April 30, 2025 10-K/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-K/A Amendment No. 1

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-K/A Amendment No.

April 25, 2025 424B3

Up to 6,370,387 Shares of Common Stock

Filed Pursuant to Rule 424(b)(3) Registration No. 333-286617 PROSPECTUS Up to 6,370,387 Shares of Common Stock This prospectus relates to the offer and sale from time to time, by the selling securityholders identified in this prospectus, of up to 6,370,387 shares of the common stock, par value $0.0001 per share (the “Common Stock”), of Eyenovia, Inc. (the “Company”) which includes (i) up to 23,771

April 24, 2025 CORRESP

April 24, 2025

April 24, 2025 Via EDGAR U.S. Securities and Exchange Commission Division of Corporation Finance 100 F Street, N.E. Washington, D.C. 20549 Attn: Tim Buchmiller Re: Eyenovia, Inc. (the “Company”) Registration Statement Filed on Form S-3 (the “Registration Statement”) File No. 333-286617 Ladies and Gentlemen: Pursuant to Rule 461 under the Securities Act of 1933, as amended, the Company hereby respe

April 23, 2025 LETTER

LETTER

April 23, 2025 Michael Rowe Chief Executive Officer Eyenovia, Inc. 23461 S. Pointe Drive, Suite 390 Laguna Hills, CA 92653 Re: Eyenovia, Inc. Registration Statement on Form S-3 Filed April 18, 2025 File No. 333-286617 Dear Michael Rowe: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for accelerat

April 18, 2025 S-3

As filed with the Securities and Exchange Commission on April 17, 2025

As filed with the Securities and Exchange Commission on April 17, 2025 Registration No: 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.

April 18, 2025 EX-FILING FEES

Filing Fee Table

Exhibit 107 Calculation of Filing Fee Tables Form S-3 (Form Type) Eyenovia, Inc. (Exact Name of Registrant as Specified in its Charter) Table 1: Newly Registered and Carry-Forward Securities Security Type Security Class Title Fee Calculation Rule Amount Registered(1) Proposed Maximum Offering Price Per Unit Maximum Aggregate Offering Price Fee Rate Amount of Registration Fee Carry Forward Form Typ

April 17, 2025 424B5

Up to $1,816,756

Filed Pursuant to Rule 424(b)(5) Registration No. 333-282458 Prospectus Supplement (To Prospectus dated October 8, 2024) Up to $1,816,756 We previously entered into an amended and restated sales agreement (the “Sales Agreement”) with Chardan Capital Markets, LLC (“Chardan”), dated as of December 30, 2024, relating to the offer and sale of shares of our common stock, $0.0001 par value per share, ha

April 15, 2025 EX-4.7

Amendment No. 1 to Warrant Issued on September 30, 2024, dated December 9, 2024

Exhibit 4.7 AMENDMENT No. 1 TO COMMON Stock PURCHASE WARRANT THIS AMENDMENT NO. 1 TO COMMON stock PURCHASE WARRANT (this “Amendment”) is entered into as of December [ ], 2024, by and between Eyenovia, Inc., a Delaware corporation (the “Company”), and Armistice Capital Master Fund Ltd. (the “Holder”). WHEREAS, the Holder is the holder of that certain common stock purchase warrant issued by the Comp

April 15, 2025 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-K ☒ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended: December 31, 2024 OR ☐TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to COMMISSION FILE NUMBER: 001-38365 EYENOVIA, INC.

April 15, 2025 EX-4.1

Exhibit 4.1

Exhibit 4.1 DESCRIPTION OF THE REGISTRANT’S SECURITIES REGISTERED PURSUANT TO SECTION 12 OF THE SECURITIES EXCHANGE ACT OF 1934 As of December 31, 2024, Eyenovia, Inc. (“we”, “our” and “us”) had one class of securities registered under Section 12 of the Securities Exchange Act of 1934, as amended: our common stock, $0.0001 par value per share. The following summary of our common stock does not pur

April 15, 2025 EX-19.1

Insider Trading Policy

Exhibit 19.1 INSIDER TRADING POLICY and Guidelines with Respect to Certain Transactions in Company Securities This Policy provides guidelines to employees, officers, directors and consultants of Eyenovia, Inc. and any subsidiaries (the “Company”) with respect to transactions in the Company’s securities and the disclosure of material nonpublic information regarding the Company. Applicability of Pol

April 15, 2025 EX-4.9

Amendment No. 1 to Warrant Issued on November 26, 2024, dated December 9, 2024

Exhibit 4.9 AMENDMENT No. 1 TO COMMON Stock PURCHASE WARRANT THIS AMENDMENT NO. 1 TO COMMON stock PURCHASE WARRANT (this “Amendment”) is entered into as of December [ ], 2024, by and between Eyenovia, Inc., a Delaware corporation (the “Company”), and Armistice Capital Master Fund Ltd. (the “Holder”). WHEREAS, the Holder is the holder of that certain common stock purchase warrant issued by the Comp

March 31, 2025 NT 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 12b-25 NOTIFICATION OF LATE FILING

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 12b-25 NOTIFICATION OF LATE FILING (Check one): x Form 10-K ¨ Form 20-F ¨ Form 11-K ¨ Form 10-Q ¨ Form 10-D ¨ Form N-CEN ¨ Form N-CSR For Period Ended: December 31, 2024 ¨ Transition Report on Form 10-K ¨ Transition Report on Form 20-F ¨ Transition Report on Form 11-K ¨ Transition Report on Form 10-Q For the Transition Pe

March 20, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 18, 2025 EYENOVIA, INC. (Ex

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 18, 2025 EYENOVIA, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 001-38365 47-1178401 (State or other jurisdiction of incorporation) (Commission File Numb

March 20, 2025 EX-99.1

Eyenovia Enters into Non-Binding Letter of Intent to effect Reverse Merger with Betaliq Combination, if successful, would be a new publicly-listed eye care company combining Betaliq’s EyeSol® water-free drug delivery technology for glaucoma with Eyen

Exhibit 99.1 Eyenovia Enters into Non-Binding Letter of Intent to effect Reverse Merger with Betaliq Combination, if successful, would be a new publicly-listed eye care company combining Betaliq’s EyeSol® water-free drug delivery technology for glaucoma with Eyenovia’s Optejet® device platform The combined company would continue marketing Eyenovia’s FDA-approved products – and plans to in-license

March 5, 2025 S-8

As filed with the Securities and Exchange Commission on March 5, 2025

As filed with the Securities and Exchange Commission on March 5, 2025 Registration No.

March 5, 2025 EX-FILING FEES

Filing Fees Exhibit.

EXHIBIT 107 Calculation of Filing Fee Table Form S-8 (Form Type) Eyenovia, Inc. (Exact Name of Registrant as Specified in its Charter) Table 1: Newly Registered Securities Security Type Security Class Title Fee Calculation Rule Amount Registered(1) Proposed Maximum Offering Price Per Unit(2) Maximum Aggregate Offering Price(2) Fee Rate Amount of Registration Fee Equity Common Stock, $0.0001 par va

February 25, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 25, 2025 EYENOVIA, INC.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 25, 2025 EYENOVIA, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 001-38365 47-1178401 (State or other jurisdiction of incorporation) (Commission File N

February 24, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 21, 2025 EYENOVIA, INC.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 21, 2025 EYENOVIA, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 001-38365 47-1178401 (State or other jurisdiction of incorporation) (Commission File N

February 24, 2025 EX-10.1

Second Amendment to Supplement to Loan and Security Agreement, dated as of February 21, 2025, by and among Eyenovia, Inc., Avenue Capital Management II, L.P., Avenue Venture Opportunities Fund, L.P. and Avenue Venture Opportunities Fund II, L.P.

Exhibit 10.1 SECOND AMENDMENT TO SUPPLEMENT TO LOAN AND SECURITY AGREEMENT This Second Amendment to Supplement to Loan and Security Agreement (this “Amendment”) is entered into as of February 21, 2025, by and among AVENUE CAPITAL MANAGEMENT II, L.P., a Delaware limited partnership (as administrative and collateral agent (in such capacity, “Agent”)), AVENUE VENTURE OPPORTUNITIES FUND, L.P., a Delaw

January 31, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 31, 2025 EYENOVIA, INC. (

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 31, 2025 EYENOVIA, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 001-38365 47-1178401 (State or other jurisdiction of incorporation) (Commission File Nu

January 31, 2025 EX-3.1

Certificate of Amendment to the Third Amended and Restated Certificate of Incorporation

Exhibit 3.1 CERTIFICATE OF AMENDMENT OF THIRD AMENDED AND RESTATED CERTIFICATE OF INCORPORATION OF EYENOVIA, INC. Pursuant to Section 242 of the General Corporation Law of the State of Delaware, Eyenovia, Inc., a corporation organized and existing under the laws of the State of Delaware (the “Corporation”), does hereby certify as follows: 1. The name of the Corporation is Eyenovia, Inc. 2. The Thi

January 28, 2025 8-K

Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 28, 2025 EYENOVIA, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 001-38365 47-1178401 (State or other jurisdiction of incorporation) (Commission File Nu

January 28, 2025 EX-99.1

Eyenovia Announces 1-for-80 Reverse Stock Split Reverse stock split, when effective, is intended to restore compliance with the Nasdaq minimum bid price requirement while Eyenovia continues to evaluate a broad range of strategic alternatives

Exhibit 99.1 Eyenovia Announces 1-for-80 Reverse Stock Split Reverse stock split, when effective, is intended to restore compliance with the Nasdaq minimum bid price requirement while Eyenovia continues to evaluate a broad range of strategic alternatives NEW YORK, January 28, 2025 – Eyenovia, Inc. (NASDAQ: EYEN) (“Eyenovia” or the “Company”), an ophthalmic technology company focused on completing

January 24, 2025 8-K

Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 21, 2025 EYENOVIA, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 001-38365 47-1178401 (State or other jurisdiction of incorporation) (Commission File Nu

January 16, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 16, 2025 EYENOVIA, INC. (

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 16, 2025 EYENOVIA, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 001-38365 47-1178401 (State or other jurisdiction of incorporation) (Commission File Nu

January 16, 2025 424B3

Up to 15,769,445 Shares of Common Stock Underlying Warrants to Purchase Shares of Common Stock

424B3 1 tm253514d2424b3.htm 424B3  Filed Pursuant to Rule 424(b)(3)  Registration No. 333-282458 PROSPECTUS SUPPLEMENT (To Prospectus dated October 8, 2024) Up to 15,769,445 Shares of Common Stock Underlying Warrants to Purchase Shares of Common Stock This prospectus supplement, dated January 16, 2025 (the “Supplement”), filed by Eyenovia, Inc. (the “Company”), modifies and supplements certain inf

January 16, 2025 EX-4.1

Form of Series A Warrant Issued on January 17, 2025

Exhibit 4.1 NEITHER THIS SECURITY NOR THE SECURITIES FOR WHICH THIS SECURITY IS EXERCISABLE HAVE BEEN REGISTERED WITH THE SECURITIES AND EXCHANGE COMMISSION OR THE SECURITIES COMMISSION OF ANY STATE IN RELIANCE UPON AN EXEMPTION FROM REGISTRATION UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), AND, ACCORDINGLY, MAY NOT BE OFFERED OR SOLD EXCEPT PURSUANT TO AN EFFECTIVE REGISTR

January 16, 2025 EX-4.2

Form of Series B Warrant Issued on January 17, 2025

Exhibit 4.2 NEITHER THIS SECURITY NOR THE SECURITIES FOR WHICH THIS SECURITY IS EXERCISABLE HAVE BEEN REGISTERED WITH THE SECURITIES AND EXCHANGE COMMISSION OR THE SECURITIES COMMISSION OF ANY STATE IN RELIANCE UPON AN EXEMPTION FROM REGISTRATION UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), AND, ACCORDINGLY, MAY NOT BE OFFERED OR SOLD EXCEPT PURSUANT TO AN EFFECTIVE REGISTR

January 16, 2025 EX-10.1

Inducement Letter, dated January 16, 2025

Exhibit 10.1 EYENOVIA, INC. 295 Madison Avenue, Suite 2400 New York, NY 10017 January 16, 2025 To the Holders of March 2022 Common Stock Purchase Warrants, August 2023 Common Stock Purchase Warrants and July 2024 Common Stock Purchase Warrants Re: Inducement Offer to Exercise Existing Common Stock Purchase Warrants Dear Holder: EYENOVIA, INC. (the “Company”) is pleased to offer (this “Inducement O

January 15, 2025 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Information Required in Proxy Statement Schedule 14A Information Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Information Required in Proxy Statement Schedule 14A Information Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a party other than the Registrant ¨ Check the appropriate box: ¨ Preliminary Proxy Statement ¨ Confidential, for Use of the Commission

December 30, 2024 424B5

Up to $33,586,557 Common Stock

Filed Pursuant to Rule 424(b)(5) Registration No. 333-282458 PROSPECTUS SUPPLEMENT (To Prospectus dated October 8, 2024) Up to $33,586,557 Common Stock We have entered into an amended and restated sales agreement (the “Sales Agreement”) with Chardan Capital Markets, LLC (“Chardan”), dated as of December 30, 2024, relating to the sale of shares of our common stock, $0.0001 par value per share, offe

December 30, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 30, 2024 EYENOVIA, INC.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 30, 2024 EYENOVIA, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 001-38365 47-1178401 (State or other jurisdiction of incorporation) (Commission File N

December 30, 2024 EX-1.1

Amended and Restated Sales Agreement, dated December 30, 2024, by and between Eyenovia, Inc. and Chardan Capital Markets, LLC

Exhibit 1.1 Execution Version EYENOVIA, INC. Shares of Common Stock ($0.0001 par value per share) AMENDED AND RESTATED SALES AGREEMENT December 30, 2024 CHARDAN CAPITAL MARKETS, LLC One Pennsylvania Avenue, Suite 4800 New York, New York 10119 Ladies and Gentlemen: Eyenovia, Inc., a Delaware corporation (the “Company”), together with Leerink Partners LLC (“Leerink Partners”) are parties to that cer

December 23, 2024 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☒ Defin

December 13, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 12, 2024 EYENOVIA, INC.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 12, 2024 EYENOVIA, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 001-38365 47-1178401 (State or other jurisdiction of incorporation) (Commission File N

December 13, 2024 PRE 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant x Filed by a Party other than the Registrant ¨ Check the appropriate box: x Preliminary Proxy Statement ¨ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ¨ Defin

December 9, 2024 EX-99.1

Eyenovia, Inc. Announces Pricing of $1.9 Million Registered Direct Offering

Exhibit 99.1 Eyenovia, Inc. Announces Pricing of $1.9 Million Registered Direct Offering December 6, 2024 at 8:00 AM EST NEW YORK, Dec. 06, 2024 (GLOBE NEWSWIRE) - Eyenovia, Inc. (NASDAQ: EYEN) (“Eyenovia” or the “Company”), an ophthalmic technology company developing and commercializing advanced products leveraging its proprietary Optejet topical ophthalmic medication dispensing platform, today a

December 9, 2024 EX-4.1

Form of Warrant Issued on December 9, 2024

Exhibit 4.1 COMMON STOCK PURCHASE WARRANT EYENOVIA, INC. Warrant Shares: 40,170,050 Issue Date: December 9, 2024 Initial Exercise Date: Stockholder Approval Date THIS COMMON STOCK PURCHASE WARRANT (this “Warrant”) certifies that, for value received, Armistice Capital Master Fund Ltd. or its assigns (the “Holder”) is entitled, upon the terms and subject to the limitations on exercise and the condit

December 9, 2024 EX-4.2

Form of Pre-Funded Warrant.

Exhibit 4.2 PRE-FUNDED COMMON STOCK PURCHASE WARRANT EYENOVIA, INC. Warrant Shares: 9,085,025 Issue Date: December 9, 2024 THIS PRE-FUNDED COMMON STOCK PURCHASE WARRANT (the “Warrant”) certifies that, for value received, Armistice Capital Master Fund Ltd. or its assigns (the “Holder”) is entitled, upon the terms and subject to the limitations on exercise and the conditions hereinafter set forth, a

December 9, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 5, 2024 EYENOVIA, INC. (

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 5, 2024 EYENOVIA, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 001-38365 47-1178401 (State or other jurisdiction of incorporation) (Commission File Nu

December 9, 2024 424B5

11,000,000 Shares of Common Stock Warrants to Purchase Up to 40,170,050 Shares of Common Stock Pre-Funded Warrants to Purchase Up to 9,085,025 Shares of Common Stock

Filed Pursuant to Rule 424(b)(5) Registration No. 333-282458 PROSPECTUS SUPPLEMENT (To Prospectus dated October 8, 2024) 11,000,000 Shares of Common Stock Warrants to Purchase Up to 40,170,050 Shares of Common Stock Pre-Funded Warrants to Purchase Up to 9,085,025 Shares of Common Stock We are offering directly to a certain institutional investor 11,000,000 shares (the “Shares”) of our common stock

December 9, 2024 EX-10.1

Form of Securities Purchase Agreement, dated December 5, 2024.

Exhibit 10.1 SECURITIES PURCHASE AGREEMENT This Securities Purchase Agreement (this “Agreement”) is dated as of December 5, 2024, between Eyenovia, Inc., a Delaware corporation (the “Company”), and each purchaser identified on the signature pages hereto (each, including its successors and assigns, a “Purchaser” and collectively the “Purchasers”). WHEREAS, subject to the terms and conditions set fo

December 4, 2024 SC 13D/A

EYEN / Eyenovia, Inc. / Grant Stuart M. - AMENDMENT NO.6 Activist Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D/A (Amendment No. 6) Under the Securities Exchange Act of 1934 Eyenovia, Inc. (Name of Issuer) Common Stock, Par Value $0.0001 per share (Title of Class of Securities) 30234E 104 (CUSIP Number) Stuart M. Grant 11 Summit Lane Greenville, DE 19807 302 449-4300 (Name, Address and Telephone Number of Person Authorized

November 26, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 24, 2024 EYENOVIA, INC.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 24, 2024 EYENOVIA, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 001-38365 47-1178401 (State or other jurisdiction of incorporation) (Commission File N

November 26, 2024 EX-99.1

Eyenovia, Inc. Announces Pricing of $1.3 Million Registered Direct Offering

Exhibit 99.1 Eyenovia, Inc. Announces Pricing of $1.3 Million Registered Direct Offering NEW YORK, Nov. 25, 2024 (GLOBE NEWSWIRE) - Eyenovia, Inc. (NASDAQ: EYEN) (“Eyenovia” or the “Company”), an ophthalmic technology company developing and commercializing advanced products leveraging its proprietary Optejet topical ophthalmic medication dispensing platform, today announced that it has entered int

November 26, 2024 EX-4.1

Form of Warrant Issued on November 26, 2024

Exhibit 4.1 COMMON STOCK PURCHASE WARRANT EYENOVIA, INC. Warrant Shares: Issue Date: November [●], 2024 Initial Exercise Date: May [●], 2025 THIS COMMON STOCK PURCHASE WARRANT (this “Warrant”) certifies that, for value received, or its assigns (the “Holder”) is entitled, upon the terms and subject to the limitations on exercise and the conditions hereinafter set forth, at any time beginning on May

November 26, 2024 424B5

9,000,000 Shares of Common Stock Warrants to Purchase Up to 24,163,570 Shares of Common Stock Pre-Funded Warrants to Purchase Up to 3,081,785 Shares of Common Stock

Filed Pursuant to Rule 424(b)(5) Registration No. 333-282458 PROSPECTUS SUPPLEMENT (To Prospectus dated October 8, 2024) 9,000,000 Shares of Common Stock Warrants to Purchase Up to 24,163,570 Shares of Common Stock Pre-Funded Warrants to Purchase Up to 3,081,785 Shares of Common Stock We are offering directly to a certain institutional investor 9,000,000 shares (the “Shares”) of our common stock,

November 26, 2024 EX-10.1

Form of Securities Purchase Agreement, dated November 24, 2024.

Exhibit 10.1 SECURITIES PURCHASE AGREEMENT This Securities Purchase Agreement (this “Agreement”) is dated as of November 24, 2024, between Eyenovia, Inc., a Delaware corporation (the “Company”), and each purchaser identified on the signature pages hereto (each, including its successors and assigns, a “Purchaser” and collectively the “Purchasers”). WHEREAS, subject to the terms and conditions set f

November 26, 2024 EX-4.2

Form of Pre-Funded Warrant.

Exhibit 4.2 PRE-FUNDED COMMON STOCK PURCHASE WARRANT EYENOVIA, INC. Warrant Shares: Issue Date: November [·], 2024 THIS PRE-FUNDED COMMON STOCK PURCHASE WARRANT (the “Warrant”) certifies that, for value received,                                   or its assigns (the “Holder”) is entitled, upon the terms and subject to the limitations on exercise and the conditions hereinafter set forth, at any tim

November 25, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 22, 2024 EYENOVIA, INC.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 22, 2024 EYENOVIA, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 001-38365 47-1178401 (State or other jurisdiction of incorporation) (Commission File N

November 25, 2024 EX-10.1

First Amendment to Supplement to Loan and Security Agreement, dated as of November 22, 2024, by and among Eyenovia, Inc., Avenue Capital Management II, L.P., Avenue Venture Opportunities Fund, L.P. and Avenue Venture Opportunities Fund II, L.P.

Exhibit 10.1 FIRST AMENDMENT TO SUPPLEMENT TO LOAN AND SECURITY AGREEMENT This First Amendment to Supplement to Loan and Security Agreement (this “Amendment”) is entered into as of November 22, 2024, by and among AVENUE CAPITAL MANAGEMENT II, L.P., a Delaware limited partnership (as administrative and collateral agent (in such capacity, “Agent”)), AVENUE VENTURE OPPORTUNITIES FUND, L.P., a Delawar

November 25, 2024 EX-10.2

Subscription Agreement, dated as of November 22, 2024, by and among Eyenovia, Inc., Avenue Venture Opportunities Fund, L.P. and Avenue Venture Opportunities Fund II, L.P.

Exhibit 10.2 SUBSCRIPTION AGREEMENT Eyenovia, Inc. 295 Madison Avenue, Suite 2400 New York, NY 10017 Ladies and Gentlemen: This Subscription Agreement (this “Subscription Agreement”) is being entered into as of the date set forth on the signature page hereto, by and among Eyenovia, Inc., a Delaware corporation (the “Company”), Avenue Venture Opportunities Fund, L.P. (“Avenue”) and Avenue Venture O

November 20, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 19, 2024 EYENOVIA, INC.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 19, 2024 EYENOVIA, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 001-38365 47-1178401 (State or other jurisdiction of incorporation) (Commission File N

November 15, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 15, 2024 EYENOVIA, INC.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 15, 2024 EYENOVIA, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 001-38365 47-1178401 (State or other jurisdiction of incorporation) (Commission File N

November 15, 2024 EX-99.1

Eyenovia Provides Update on Phase 3 CHAPERONE Study A review of study data by an independent Data Review Committee found that CHAPERONE is not meeting its primary three-year efficacy endpoint Company to discontinue study, review full data set, and ev

Exhibit 99.1 Eyenovia Provides Update on Phase 3 CHAPERONE Study A review of study data by an independent Data Review Committee found that CHAPERONE is not meeting its primary three-year efficacy endpoint Company to discontinue study, review full data set, and evaluate next steps for the program NEW YORK— November 15, 2024—Eyenovia, Inc. (NASDAQ: EYEN), an ophthalmic technology company, today anno

November 14, 2024 SC 13G/A

EYEN / Eyenovia, Inc. / ARMISTICE CAPITAL, LLC Passive Investment

SC 13G/A 1 armistice-eyen093024a1.htm UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934 (Amendment No. 1)* EYENOVIA, INC. (Name of Issuer) Common Stock, par value $0.0001 per share (Title of Class of Securities) 30234E104 (CUSIP Number) September 30, 2024 (Date of Event Which Requires Filing of this Statement) Check the a

November 13, 2024 S-8

As filed with the Securities and Exchange Commission on November 12, 2024

As filed with the Securities and Exchange Commission on November 12, 2024 Registration No.

November 13, 2024 EX-FILING FEES

Filing Fees Exhibit.

Exhibit 107 CALCULATION OF FILING FEE TABLE Form S-8 (Form Type) Eyenovia, Inc. (Exact Name of Registrant as Specified in its Charter) Table 1: Newly Registered Securities Security Type Security Class Title Fee Calculation Rule Amount Registered Proposed Maximum Offering Price Per Unit Maximum Aggregate Offering Price Fee Rate Amount of Registration Fee Equity Common Stock, $0.0001 par value per s

November 12, 2024 EX-10.8

Form of Indemnification and Advancement Agreement

Exhibit 10.8 INDEMNIFICATION AND ADVANCEMENT AGREEMENT This Indemnification and Advancement Agreement (“Agreement”) is made as of , 2024 by and between Eyenovia, Inc., a Delaware corporation (the “Company”), and [name], [a member of the Board of Directors/an officer/an employee/an agent] of the Company (“Indemnitee”). This Agreement supersedes and replaces any and all previous Agreements between t

November 12, 2024 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended: September 30, 2024 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to COMMISSION FILE NUMBER: 001-38365 EYENOVIA, INC.

November 12, 2024 EX-10.7

Form of Notice of Inducement Stock Option Grant

Exhibit 10.7 EYENOVIA, INC. NOTICE OF INDUCEMENT STOCK OPTION GRANT (Grantee name and address) You have been granted an option to purchase shares of the Common Stock of Eyenovia, Inc. as follows, subject to the terms and conditions of the attached Inducement Stock Option Award Agreement. Capitalized terms used but not defined in this Notice of Inducement Stock Option Grant have the meanings set fo

November 12, 2024 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 12, 2024 EYENOVIA, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 001-38365 47-1178401 (State or other jurisdiction of incorporation) (Commission File N

November 12, 2024 EX-99.1

Eyenovia Reports Third Quarter 2024 Financial Results and Provides Corporate Update Advanced Phase 3 CHAPERONE study of MicroPine as a treatment of pediatric progressive myopia with preparations for interim analysis this quarter Commenced the manufac

Exhibit 99.1 Eyenovia Reports Third Quarter 2024 Financial Results and Provides Corporate Update Advanced Phase 3 CHAPERONE study of MicroPine as a treatment of pediatric progressive myopia with preparations for interim analysis this quarter Commenced the manufacture of registration batches of Mydcombi in its second generation Optejet device Announced the U.S. launch and commercial availability of

October 4, 2024 CORRESP

October 4, 2024

October 4, 2024 Via EDGAR U.S. Securities and Exchange Commission Division of Corporation Finance 100 F Street, N.E. Washington, D.C. 20549 Attn: Joshua Gorsky Re: Eyenovia, Inc. (the “Company”) Registration Statement Filed on Form S-3 (the “Registration Statement”) File No. 333-282458 Ladies and Gentlemen: Pursuant to Rule 461 under the Securities Act of 1933, as amended, the Company hereby respe

October 4, 2024 LETTER

LETTER

October 4, 2024 Michael Rowe Chief Executive Officer Eyenovia, Inc. 295 Madison Avenue, Suite 2400 New York, New York 10017 Re: Eyenovia, Inc. Registration Statement on Form S-3 Filed October 1, 2024 File No. 333-282458 Dear Michael Rowe: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceler

October 1, 2024 S-3

As filed with the Securities and Exchange Commission on October 1, 2024

As filed with the Securities and Exchange Commission on October 1, 2024 Registration No: 333-       UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.

October 1, 2024 EX-4.1

Form of Indenture

Exhibit 4.1 EYENOVIA, INC. INDENTURE Dated as of , 20 [] Trustee TABLE OF CONTENTS ARTICLE I. DEFINITIONS AND INCORPORATION BY REFERENCE 1 Section 1.1. Definitions. 1 Section 1.2. Other Definitions. 3 Section 1.3. Incorporation by Reference of Trust Indenture Act. 4 Section 1.4. Rules of Construction. 4 ARTICLE II. THE SECURITIES 4 Section 2.1. Issuable in Series. 4 Section 2.2. Establishment of T

October 1, 2024 EX-FILING FEES

Filing Fee Table

Exhibit 107 Calculation of Filing Fee Tables Form S-3 (Form Type) Eyenovia, Inc. (Exact Name of Registrant as Specified in its Charter) Table 1: Newly Registered and Carry Forward Securities Security Type Security Class Title Fee Calculation or Carry Forward Rule Amount Registered(1) Proposed Maximum Offering Price Per Unit(1) Maximum Aggregate Offering Price(1) Fee Rate Amount of Registration Fee

September 30, 2024 EX-10.1

Form of Securities Purchase Agreement, dated September 26, 2024.

Exhibit 10.1 SECURITIES PURCHASE AGREEMENT This Securities Purchase Agreement (this “Agreement”) is dated as of September 26, 2024, between Eyenovia, Inc., a Delaware corporation (the “Company”), and each purchaser identified on the signature pages hereto (each, including its successors and assigns, a “Purchaser” and collectively the “Purchasers”). WHEREAS, subject to the terms and conditions set

September 30, 2024 424B5

      8,630,000 Shares of Common Stock Warrants to Purchase Up to 8,695,653 Shares of Common Stock Pre-Funded Warrants to Purchase Up to 65,653 Shares of Common Stock

TABLE OF CONTENTS  Filed Pursuant to Rule 424(b)(5)  Registration No. 333-261638 PROSPECTUS SUPPLEMENT (To Prospectus dated December 23, 2021)       8,630,000 Shares of Common Stock Warrants to Purchase Up to 8,695,653 Shares of Common Stock Pre-Funded Warrants to Purchase Up to 65,653 Shares of Common Stock We are offering directly to a certain purchaser 8,630,000 shares (the “Shares”) of our com

September 30, 2024 EX-4.2

Form of Pre-Funded Warrant.

Exhibit 4.2 PRE-FUNDED COMMON STOCK PURCHASE WARRANT EYENOVIA, INC. Warrant Shares: 65,653 Issue Date: September 30, 2024 THIS PRE-FUNDED COMMON STOCK PURCHASE WARRANT (the “Warrant”) certifies that, for value received, or its assigns (the “Holder”) is entitled, upon the terms and subject to the limitations on exercise and the conditions hereinafter set forth, at any time beginning on September 30

September 30, 2024 EX-4.1

Form of Warrant Issued on September 30, 2024

Exhibit 4.1 COMMON STOCK PURCHASE WARRANT EYENOVIA, INC. Warrant Shares: 8,695,653 Initial Exercise Date: March 31, 2025 Issue Date: September 30, 2024 THIS COMMON STOCK PURCHASE WARRANT (the “Warrant”) certifies that, for value received, or its assigns (the “Holder”) is entitled, upon the terms and subject to the limitations on exercise and the conditions hereinafter set forth, at any time beginn

September 30, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 26, 2024 EYENOVIA, INC.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 26, 2024 EYENOVIA, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 001-38365 47-1178401 (State or other jurisdiction of incorporation) (Commission File

September 30, 2024 EX-99.1

Eyenovia, Inc. Announces Pricing of $4 Million Registered Direct Offering

Exhibit 99.1 Eyenovia, Inc. Announces Pricing of $4 Million Registered Direct Offering NEW YORK, Sept. 27, 2024 (GLOBE NEWSWIRE) - Eyenovia, Inc. (NASDAQ: EYEN) (“Eyenovia” or the “Company”), an ophthalmic technology company with two FDA-approved products and a late-stage asset in development for the treatment of pediatric progressive myopia, today announced it has entered into a securities purcha

September 20, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 18, 2024 EYENOVIA, INC.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 18, 2024 EYENOVIA, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 001-38365 47-1178401 (State or other jurisdiction of incorporation) (Commission File

September 3, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 30, 2024 EYENOVIA, INC. (E

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 30, 2024 EYENOVIA, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 001-38365 47-1178401 (State or other jurisdiction of incorporation) (Commission File Num

September 3, 2024 EX-10.1

Executive Employment Agreement by and between Eyenovia, Inc. and Andrew D. Jones, dated as of August 30, 2024

Exhibit 10.1   EXECUTIVE EMPLOYMENT AGREEMENT   THIS EXECUTIVE EMPLOYMENT AGREEMENT (the “Agreement”) is made and effective this 30th day of August 2024 (the “Effective Date”), by and between Eyenovia, Inc., a Delaware corporation (the “Company”), and Andrew D. Jones, an individual resident of California (“Executive”). The Company and Executive are herein referred to each as a “Party” and together

September 3, 2024 EX-99.1

Eyenovia Announces Appointment of Experienced Finance and Accounting Executive Andrew Jones as Chief Financial Officer Current CFO, John Gandolfo, to remain with the Company through November as part of planned retirement transition

Exhibit 99.1 Eyenovia Announces Appointment of Experienced Finance and Accounting Executive Andrew Jones as Chief Financial Officer Current CFO, John Gandolfo, to remain with the Company through November as part of planned retirement transition NEW YORK— September 3, 2024—Eyenovia, Inc. (NASDAQ: EYEN), a commercial-stage ophthalmic company with two FDA-approved products and a late-stage asset in p

August 23, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 23, 2024 EYENOVIA, INC. (E

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 23, 2024 EYENOVIA, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 001-38365 47-1178401 (State or other jurisdiction of incorporation) (Commission File Num

August 23, 2024 EX-99.1

August 2024 Our Vision is to Improve Yours With topical ophthalmic therapies that are easier to use and easier to live with EYEN-COM-V2-0021 Forward-looking Statements Except for historical information, all the statements, expectations and assumption

Exhibit 99.1 August 2024 Our Vision is to Improve Yours With topical ophthalmic therapies that are easier to use and easier to live with EYEN-COM-V2-0021 Forward-looking Statements Except for historical information, all the statements, expectations and assumptions contained in this presentation are forward-looking statements. Forward-looking statements include, but are not limited to, statements t

August 22, 2024 EX-10.1

Form of Securities Purchase Agreement, dated August 21, 2024

Exhibit 10.1 SECURITIES PURCHASE AGREEMENT This Securities Purchase Agreement (this “Agreement”) is dated as of August 21, 2024, between Eyenovia, Inc., a Delaware corporation (the “Company”), and each purchaser identified on the signature pages hereto (each, including its successors and assigns, a “Purchaser” and collectively the “Purchasers”). WHEREAS, subject to the terms and conditions set for

August 22, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 20, 2024 EYENOVIA, INC. (E

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 20, 2024 EYENOVIA, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 001-38365 47-1178401 (State or other jurisdiction of incorporation) (Commission File Num

August 22, 2024 EX-99.2

Eyenovia Announces Pricing of $5.14 Million Public Offering

Exhibit 99.2 Eyenovia Announces Pricing of $5.14 Million Public Offering August 21, 2024 NEW YORK, August 21, 2024 (GLOBE NEWSWIRE) – Eyenovia, Inc. (“Eyenovia” or the “Company”) (NASDAQ: EYEN), a commercial-stage ophthalmic company, announced today that it has agreed to sell 12,850,000 shares of common stock at a price per share of $0.40 (the "Offering"). The closing of the Offering is expected t

August 22, 2024 EX-99.1

Eyenovia, Inc. Announces Proposed Public Offering

Exhibit 99.1 Eyenovia, Inc. Announces Proposed Public Offering NEW YORK, August 20, 2024 (GLOBE NEWSWIRE) – Eyenovia, Inc. (“Eyenovia” or the “Company”) (NASDAQ: EYEN), a commercial-stage ophthalmic company, announced today that it intends to offer and sell shares of its common stock (or pre-funded warrants in lieu thereof) in a best efforts offering. All of the securities to be sold in the offeri

August 21, 2024 424B5

12,850,000 Shares of Common Stock

TABLE OF CONTENTS   Filed Pursuant to Rule 424(b)(5)   Registration No. 333-261638 PROSPECTUS SUPPLEMENT (To Prospectus dated December 23, 2021) 12,850,000 Shares of Common Stock We are offering directly to certain purchasers 12,850,000 shares of our common stock, par value $0.0001 per share (the “Common Stock”) at a price of $0.40 per share for an aggregate purchase price of $5,140,000. The Commo

August 21, 2024 424B5

Subject to Completion Preliminary Prospectus Supplement dated August 20, 2024

TABLE OF CONTENTS The information in this preliminary prospectus supplement is not complete and may be changed.

August 14, 2024 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended: June 30, 2024 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to COMMISSION FILE NUMBER: 001-38365 EYENOVIA, INC.

August 13, 2024 EX-99.1

Eyenovia Reports Second Quarter 2024 Financial Results and Provides Corporate Update Following FDA consultation, announced plans for validation of the Gen-2 Optejet® device and 2025 regulatory submission with Mydcombi™ as lead product Advanced Phase

Exhibit 99.1 Eyenovia Reports Second Quarter 2024 Financial Results and Provides Corporate Update Following FDA consultation, announced plans for validation of the Gen-2 Optejet® device and 2025 regulatory submission with Mydcombi™ as lead product Advanced Phase 3 CHAPERONE study of MicroPine as a treatment of pediatric progressive myopia with preparations for analysis in Q4 Commenced sales activi

August 13, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 12, 2024 EYENOVIA, INC. (E

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 12, 2024 EYENOVIA, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 001-38365 47-1178401 (State or other jurisdiction of incorporation) (Commission File Num

July 29, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 26, 2024 EYENOVIA, INC. (Exa

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 26, 2024 EYENOVIA, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 001-38365 47-1178401 (State or other jurisdiction of incorporation) (Commission File Numbe

July 18, 2024 SC 13D/A

EYEN / Eyenovia, Inc. / Ianchulev Tsontcho - SC 13D/A Activist Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D Under the Securities Exchange Act of 1934 (Amendment No. 7)* Eyenovia, Inc. (Name of Issuer) Common Stock, $0.0001 par value (Title of Class of Securities) 30234E 104 (CUSIP Number) Tsontcho Ianchulev 295 Madison Avenue, Suite 2400 New York, NY 10017 917-289-1117 (Name, Address and Telephone Number of Person Autho

July 5, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 2, 2024 EYENOVIA, INC. (Exac

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 2, 2024 EYENOVIA, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 001-38365 47-1178401 (State or other jurisdiction of incorporation) (Commission File Number

July 1, 2024 EX-99.1

Eyenovia Announces Pricing of $5M Registered Direct Offering

Exhibit 99.1 Eyenovia Announces Pricing of $5M Registered Direct Offering NEW YORK, June 28, 2024 (GLOBE NEWSWIRE) – Eyenovia, Inc. (“Eyenovia” or the “Company”) (NASDAQ: EYEN), a commercial-stage ophthalmic company, announced today that it has entered into a securities purchase agreement with an institutional investor and its current largest stockholder, providing for the purchase and sale of 7,5

July 1, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 27, 2024 EYENOVIA, INC. (Exa

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 27, 2024 EYENOVIA, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 001-38365 47-1178401 (State or other jurisdiction of incorporation) (Commission File Numbe

July 1, 2024 424B3

Warrants to Purchase 9,708,839 Shares of Common Stock

Filed pursuant to Rule 424(b)(3) Registration No. 333-261638 PROSPECTUS SUPPLEMENT (To Prospectus dated December 23, 2021) Warrants to Purchase 9,708,839 Shares of Common Stock This prospectus supplement, dated July 1, 2024 (the “Supplement”), filed by Eyenovia, Inc. (the “Company”), modifies and supplements certain information contained in (i) the Company’s prospectus supplement, dated March 4, 2

July 1, 2024 EX-10.1

Form of Securities Purchase Agreement, dated June 27, 2024

Exhibit 10.1 Execution Version SECURITIES PURCHASE AGREEMENT This Securities Purchase Agreement (this “Agreement”) is dated as of June 27, 2024, between Eyenovia, Inc., a Delaware corporation (the “Company”), and each purchaser identified on the signature pages hereto (each, including its successors and assigns, a “Purchaser” and collectively the “Purchasers”). WHEREAS, subject to the terms and co

July 1, 2024 EX-10.2

Warrant Amendment Agreement, dated June 27, 2024

Exhibit 10.2 June 27, 2024 Holder of Warrants to Purchase Common Stock Re: Amendment to Existing Warrants Dear [***] (the “Holder”): This letter confirms that Eyenovia, Inc., a Delaware corporation (the “Company”), hereby amends, effective as of the date hereof, the Holder’s existing warrants to purchase up to 9,708,839 shares of the Company’s common stock, par value $0.0001 per share (“Common Sto

July 1, 2024 EX-4.1

Form of Warrant

Exhibit 4.1 COMMON STOCK PURCHASE WARRANT EYENOVIA, INC. Warrant Shares: [] Initial Exercise Date: January 1, 2025 Issue Date: July 1, 2024 THIS COMMON STOCK PURCHASE WARRANT (the “Warrant”) certifies that, for value received, or its assigns (the “Holder”) is entitled, upon the terms and subject to the limitations on exercise and the conditions hereinafter set forth, at any time beginning on Janua

July 1, 2024 EX-10.3

Warrant Amendment Agreement, dated June 28, 2024

Exhibit 10.3 June 28, 2024 Holder of Warrants to Purchase Common Stock Issued on March 24, 2020 Re: Amendment to Existing Warrants Dear [***] (the “Holder”): This letter confirms that Eyenovia, Inc., a Delaware corporation (the “Company”), hereby amends, effective as of the date hereof, the Holder’s existing warrants to purchase up to 677,430 shares of the Company’s common stock, par value $0.0001

June 28, 2024 424B5

7,575,757 Shares of Common Stock Warrants to Purchase Up to 9,325,537 Shares of Common Stock

TABLE OF CONTENTS  Filed Pursuant to Rule 424(b)(5)  Registration No. 333-261638 PROSPECTUS SUPPLEMENT (To Prospectus dated December 23, 2021) 7,575,757 Shares of Common Stock Warrants to Purchase Up to 9,325,537 Shares of Common Stock We are offering directly to certain purchasers 7,575,757 shares (the “Shares”) of our common stock, par value $0.0001 per share (the “Common Stock”) and warrants to

June 14, 2024 EX-3.1

Certificate of Amendment to the Third Amended and Restated Certificate of Incorporation

Exhibit 3.1 CERTIFICATE OF AMENDMENT OF THIRD AMENDED AND RESTATED CERTIFICATE OF INCORPORATION OF EYENOVIA, INC. (Pursuant to Section 242 of the General Corporation Law of the State of Delaware) Eyenovia, Inc. (the “Corporation”), a corporation duly organized and existing under the General Corporation Law of the State of Delaware (the “General Corporation Law”), does hereby certify that: 1. The n

June 14, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 12, 2024 EYENOVIA, INC. (Exa

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 12, 2024 EYENOVIA, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 001-38365 47-1178401 (State or other jurisdiction of incorporation) (Commission File Numbe

June 4, 2024 EX-99.1

June 2024 We Are the Optejet® Company Developing and commercializing ophthalmic therapeutics with Optecare Ρ services in large markets with high unmet needs EYEN - COM - V2 - 0021

Exhibit 99.1 June 2024 We Are the Optejet® Company Developing and commercializing ophthalmic therapeutics with Optecare Ρ services in large markets with high unmet needs EYEN - COM - V2 - 0021 Forward - looking Statements Except for historical information, all the statements, expectations and assumptions contained in this presentation are forwar d - l ooking statements. Forward - looking statement

June 4, 2024 8-K

Regulation FD Disclosure, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 4, 2024 EYENOVIA, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 001-38365 47-1178401 (State or other jurisdiction of incorporation) (Commission File Number

May 16, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 16, 2024 EYENOVIA, INC. (Exac

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 16, 2024 EYENOVIA, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 001-38365 47-1178401 (State or other jurisdiction of incorporation) (Commission File Number

May 16, 2024 424B5

Up to $10,000,000 Common Stock

Filed Pursuant to Rule 424(b)(5) Registration No. 333-261638 PROSPECTUS SUPPLEMENT (To Prospectus dated December 23, 2021) Up to $10,000,000 Common Stock We have entered into an open market sales agreement (the “Sales Agreement”) with Leerink Partners LLC (“Leerink Partners”), dated as of December 14, 2021, relating to the sale of shares of our common stock, $0.0001 par value per share, offered by

May 15, 2024 EX-99.1

Eyenovia Reports First Quarter 2024 Financial Results and Provides Updates on its Myopia Phase III Program and its Two FDA Approved Commercial Products, Mydcombi and Clobetasol Remains on track towards accelerating development of its late-stage produ

Exhibit 99.1 Eyenovia Reports First Quarter 2024 Financial Results and Provides Updates on its Myopia Phase III Program and its Two FDA Approved Commercial Products, Mydcombi and Clobetasol Remains on track towards accelerating development of its late-stage product candidate in the multi-billion-dollar pediatric progressive myopia market, MicroPine Preparing for a 3Q 2024 launch of the first new o

May 15, 2024 EX-10.1

Letter Agreement, by and between Eyenovia, Inc. and Bausch + Lomb Ireland Limited , dated January 12, 2024.

Exhibit 10.1 [Pursuant to Item 601(b)(10)(iv) of Regulation S-K, certain identified portions of this exhibit have been omitted by means of marking such portions with asterisks as the identified portions are both not material and the type that the registrant treats as private or confidential.] January 12, 2024 CONFIDENTIAL VIA EMAIL AND COURIER [***] Bausch and Lomb 3013 Lake Drive Citywest Busines

May 15, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 15, 2024 EYENOVIA, INC. (Exac

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 15, 2024 EYENOVIA, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 001-38365 47-1178401 (State or other jurisdiction of incorporation) (Commission File Number

May 15, 2024 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended: March 31, 2024 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to COMMISSION FILE NUMBER: 001-38365 EYENOVIA, INC.

May 6, 2024 ARS

ANNUAL REPORT

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May 3, 2024 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A (RULE 14a-101) SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(A) of the Securities Exchange Act of 1934

TABLE OF CONTENTS UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A (RULE 14a-101) SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(A) of the Securities Exchange Act of 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement. ☐ Confidential, for Use of the Commission Only

April 26, 2024 10-K/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-K/A Amendment No. 1

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-K/A Amendment No.

April 23, 2024 PRE 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A (RULE 14a-101) SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(A) of the Securities Exchange Act of 1934

TABLE OF CONTENTS UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A (RULE 14a-101) SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(A) of the Securities Exchange Act of 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☒ Preliminary Proxy Statement. ☐ Confidential, for Use of the Commission Only

April 10, 2024 424B5

3,223,726 Shares of Common Stock

TABLE OF CONTENTS  Filed Pursuant to Rule 424(b)(5)  Registration No. 333-261638 PROSPECTUS SUPPLEMENT (To Prospectus dated December 23, 2021) 3,223,726 Shares of Common Stock We are offering directly to certain purchasers 3,223,726 shares of our common stock, par value $0.0001 per share (the “Common Stock”) at a price of $0.6204 per share for an aggregate purchase price of $2,000,000. The Common

April 10, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 9, 2024 EYENOVIA, INC. (Exa

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 9, 2024 EYENOVIA, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 001-38365 47-1178401 (State or other jurisdiction of incorporation) (Commission File Numbe

April 9, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 8, 2024 EYENOVIA, INC. (Exa

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 8, 2024 EYENOVIA, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 001-38365 47-1178401 (State or other jurisdiction of incorporation) (Commission File Numbe

April 9, 2024 EX-10.1

Form of Securities Purchase Agreement, dated April 8, 2024.

Exhibit 10.1 Execution Copy SECURITIES PURCHASE AGREEMENT This Securities Purchase Agreement (this “Agreement”) is dated as of April 8, 2024, between Eyenovia, Inc., a Delaware corporation (the “Company”), and each purchaser identified on the signature pages hereto (each, including its successors and assigns, a “Purchaser” and collectively the “Purchasers”). WHEREAS, subject to the terms and condi

April 8, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 8, 2024 EYENOVIA, INC. (Exa

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 8, 2024 EYENOVIA, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 001-38365 47-1178401 (State or other jurisdiction of incorporation) (Commission File Numbe

March 19, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 19, 2024 EYENOVIA, INC. (Ex

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 19, 2024 EYENOVIA, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 001-38365 47-1178401 (State or other jurisdiction of incorporation) (Commission File Numb

March 19, 2024 EX-99.1

Forward-looking Statements Except for historical information, all the statements, expectations and assumptions contained in this presentation are forward-looking statements. Forward-looking statements include, but are not limited to, statements that

Exhibit 99.1 March 2024 We Are the Optejet® Company Developing and commercializing ophthalmic therapeutics with Optecare services in large markets with high unmet needs EYEN-COM-V2-0021 Forward-looking Statements Except for historical information, all the statements, expectations and assumptions contained in this presentation are forward-looking statements. Forward-looking statements include, but

March 18, 2024 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-K

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-K ☒ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended: December 31, 2023 OR ☐TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to COMMISSION FILE NUMBER: 001-38365 EYENOVIA, INC.

March 18, 2024 EX-10.38

Mutual Termination and Reassignment, dated January 12, 2024, by and between Eyenovia, Inc and Bausch + Lomb Ireland Limited

Exhibit 10.38 [Pursuant to Item 601(b)(10)(iv) of Regulation S-K, certain identified portions of this exhibit have been omitted by means of marking such portions with asterisks as the identified portions are both not material and the type that the registrant treats as private or confidential.] January 12, 2024 CONFIDENTIAL VIA EMAIL AND COURIER [***] Bausch and Lomb 3013 Lake Drive Citywest Busine

March 18, 2024 EX-97.1

Policy Relating to Recovery of Erroneously Awarded Compensation

Exhibit 97.1 Eyenovia, Inc. Compensation Clawback Policy Adopted October 4, 2023 Purpose The Board of Directors (the “Board”) of Eyenovia, Inc. (the “Corporation”) has adopted this compensation clawback policy (the “Policy”) which provides for the recoupment of incentive-based compensation in the event of an accounting restatement. This Policy is intended to comply with Section 10D of the Securiti

February 14, 2024 SC 13G

EYEN / Eyenovia, Inc. / ARMISTICE CAPITAL, LLC Passive Investment

SC 13G 1 armistice-eyen123123.htm UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* EYENOVIA, INC. (Name of Issuer) Common Stock, par value $0.0001 per share (Title of Class of Securities) 30234E104 (CUSIP Number) December 31, 2023 (Date of Event Which Requires Filing of this Statement) Check the appropria

January 31, 2024 8-K/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K/A (Amendment No. 1) CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 25, 2

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K/A (Amendment No. 1) CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 25, 2024 EYENOVIA, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 001-38365 47-1178401 (State or other jurisdiction of incorporation)

January 31, 2024 EX-99.1

January 2024 We Are the Optejet® Company Developing and commercializing ophthalmic drug - device therapeutics with Optecare Ρ services in large markets with high unmet needs EYEN - COM - V2 - 0021

Exhibit 99.1 January 2024 We Are the Optejet® Company Developing and commercializing ophthalmic drug - device therapeutics with Optecare Ρ services in large markets with high unmet needs EYEN - COM - V2 - 0021 Forward - looking Statements Except for historical information, all the statements, expectations and assumptions contained in this presentation are forwar d - l ooking statements. Forward -

January 25, 2024 EX-99.1

Eyenovia, Inc. Updated Corporate Presentation, dated January 2024

Exhibit 99.1

January 25, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 25, 2024 EYENOVIA, INC. (

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 25, 2024 EYENOVIA, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 001-38365 47-1178401 (State or other jurisdiction of incorporation) (Commission File Nu

January 16, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 16, 2024 EYENOVIA, INC. (

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 16, 2024 EYENOVIA, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 001-38365 47-1178401 (State or other jurisdiction of incorporation) (Commission File Nu

January 16, 2024 EX-99.1

Eyenovia Re-Acquires Development and Commercialization Rights to MicroPine in the U.S. and Canada MicroPine, currently in late phase III for pediatric progressive myopia, to complement Eyenovia’s commercial-stage asset, Mydcombi, as well as its pre-P

Exhibit 99.1 Eyenovia Re-Acquires Development and Commercialization Rights to MicroPine in the U.S. and Canada MicroPine, currently in late phase III for pediatric progressive myopia, to complement Eyenovia’s commercial-stage asset, Mydcombi, as well as its pre-PDUFA candidate, APP13007 Part of corporate strategy to expedite commercialization of advanced products using the Optejet device Market es

November 13, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 10, 2023 EYENOVIA, INC.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 10, 2023 EYENOVIA, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 001-38365 47-1178401 (State or other jurisdiction of incorporation) (Commission File N

November 13, 2023 EX-10.1

License Agreement, dated August 15, 2023, by and between Eyenovia, Inc. and Formosa Pharmaceuticals, Inc.

Exhibit 10.1 Execution Version Certain confidential portions of this Exhibit were omitted by means of marking such portions with brackets (“[***]”) because the identified confidential portions (i) are not material and (ii) contain the type of information that the registrant treats as private or confidential. LICENSE AGREEMENT dated August 15, 2023 by and between FORMOSA PHARMACEUTICALS, INC. and E

November 13, 2023 EX-99.1

Eyenovia Reports Third Quarter 2023 Financial Results and Provides Business Update Acquired U.S. commercial rights to APP13007, currently under FDA review for post-surgical ocular pain and inflammation, from Formosa Pharmaceuticals Announced FDA appr

Exhibit 99.1 Eyenovia Reports Third Quarter 2023 Financial Results and Provides Business Update Acquired U.S. commercial rights to APP13007, currently under FDA review for post-surgical ocular pain and inflammation, from Formosa Pharmaceuticals Announced FDA approval of Coastline International as contract manufacturer for Mydcombi cartridge subassemblies and preparations for national launch Compan

November 13, 2023 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended: September 30, 2023 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to COMMISSION FILE NUMBER: 001-38365 EYENOVIA, INC.

November 13, 2023 EX-99.2

November 2023 FOCUS: INCREASING VALUE NOW AND IN THE FUTURE Forward-looking Statements Except for historical information, all the statements, expectations and assumptions contained in this presentation are forward-looking statements. Forward-looking

Exhibit 99.2 November 2023 FOCUS: INCREASING VALUE NOW AND IN THE FUTURE Forward-looking Statements Except for historical information, all the statements, expectations and assumptions contained in this presentation are forward-looking statements. Forward-looking statements include, but are not limited to, statements that express our intentions, beliefs, expectations, strategies, predictions or any

September 20, 2023 EX-99.1

1 Forward-looking Statements Except for historical information, all the statements, expectations and assumptions contained in this presentation are forward-looking statements. Forward-looking statements include, but are not limited to, statements tha

Exhibit 99.1 September 2023 EYEN-COM-V2-0012 1 Forward-looking Statements Except for historical information, all the statements, expectations and assumptions contained in this presentation are forward-looking statements. Forward-looking statements include, but are not limited to, statements that express our intentions, beliefs, expectations, strategies, predictions or any other statements relating

September 20, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 19, 2023 EYENOVIA, INC.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 19, 2023 EYENOVIA, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 001-38365 47-1178401 (State or other jurisdiction of incorporation) (Commission File

August 30, 2023 424B3

Warrants to Purchase 4,870,130 Shares of Common Stock

 Filed pursuant to Rule 424(b)(3)  Registration No. 333-261638 PROSPECTUS SUPPLEMENT (To Prospectus dated December 23, 2021) Warrants to Purchase 4,870,130 Shares of Common Stock This prospectus supplement, dated August 29, 2023 (the “Supplement”), filed by Eyenovia, Inc. (the “Company”), modifies and supplements certain information contained in the Company’s prospectus supplement, dated March 7,

August 29, 2023 EX-4.1

Form of Warrant Issued on August 29, 2023

Exhibit 4.1 COMMON STOCK PURCHASE WARRANT EYENOVIA, INC. Warrant Shares: 4,838,709 Issue Date: August 29, 2023 THIS COMMON STOCK PURCHASE WARRANT (the “Warrant”) certifies that, for value received, or its assigns (the “Holder”) is entitled, upon the terms and subject to the limitations on exercise and the conditions hereinafter set forth, at any time beginning on March 1, 2024 (the “Initial Exerci

August 29, 2023 EX-4.2

Form of Warrant issued on August 29, 2023

Exhibit 4.2 PREFUNDED COMMON STOCK PURCHASE WARRANT EYENOVIA, INC. Warrant Shares: 2,252,979 Issue Date: August 29, 2023 THIS PREFUNDED COMMON STOCK PURCHASE WARRANT (the “Warrant”) certifies that, for value received, or its assigns (the “Holder”) is entitled, upon the terms and subject to the limitations on exercise and the conditions hereinafter set forth, at any time on or after the date hereof

August 29, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 24, 2023 EYENOVIA, INC. (E

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 24, 2023 EYENOVIA, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 001-38365 47-1178401 (State or other jurisdiction of incorporation) (Commission File Num

August 29, 2023 EX-10.1

Securities Purchase Agreement, dated August 24, 2023

Exhibit 10.1 SECURITIES PURCHASE AGREEMENT This Securities Purchase Agreement (this “Agreement”) is dated as of August 24, 2023, between Eyenovia, Inc., a Delaware corporation (the “Company”), and the purchaser identified on the signature pages hereto (including its successors and assigns, the “Purchaser”). WHEREAS, subject to the terms and conditions set forth in this Agreement and pursuant to an

August 29, 2023 EX-99.1

EYENOVIA ANNOUNCES $12 MILLION REGISTERED DIRECT OFFERING

Exhibit 99.1 EYENOVIA ANNOUNCES $12 MILLION REGISTERED DIRECT OFFERING NEW YORK, August 24, 2023 (GLOBE NEWSWIRE) - Eyenovia, Inc. (NASDAQ: EYEN), a commercial-stage ophthalmic technology company commercializing Mydcombi™ (tropicamide+phenylephrine ophthalmic spray for mydriasis) and developing the Optejet® device for use both in connection with its own drug-device therapeutic product candidates f

August 29, 2023 EX-10.2

Warrant Amendment Agreement, dated August 24, 2023

Exhibit 10.2 August 24, 2023 Holder of Warrants to Purchase Common Stock Issued on March 7, 2022 Re: Amendment to Existing Warrants Dear [***] (the “Holder”): This letter confirms that Eyenovia, Inc., a Delaware corporation (the “Company”), hereby amends, effective as of the date hereof, the Holder’s existing warrants to purchase up to 4,870,130 shares of the Company’s common stock, par value $0.0

August 25, 2023 424B5

4,198,633 Shares of Common Stock Warrants to Purchase Up to 4,838,709 Shares of Common Stock Pre-Funded Warrants to Purchase up to 2,252,979 Shares of Common Stock

TABLE OF CONTENTS  Filed pursuant to Rule 424(b)(5)  Registration No. 333-261638 PROSPECTUS SUPPLEMENT (To Prospectus dated December 23, 2021) 4,198,633 Shares of Common Stock Warrants to Purchase Up to 4,838,709 Shares of Common Stock Pre-Funded Warrants to Purchase up to 2,252,979 Shares of Common Stock We are offering 4,198,633 shares of our common stock (the “Shares”), par value $0.0001 per sh

August 16, 2023 EX-99.1

Eyenovia Acquires U.S. Commercial Rights to APP13007 (Clobetasol Propionate Ophthalmic Nanosuspension, 0.05%) from Formosa Pharmaceuticals APP13007, if approved, may have an advantageous profile in dosing frequency and side effects while reducing the

Exhibit 99.1 Eyenovia Acquires U.S. Commercial Rights to APP13007 (Clobetasol Propionate Ophthalmic Nanosuspension, 0.05%) from Formosa Pharmaceuticals APP13007, if approved, may have an advantageous profile in dosing frequency and side effects while reducing the inflammation and pain associated with ocular surgery Further leverages Eyenovia’s Mydcombi sales force and represents additional near-te

August 16, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 15, 2023 EYENOVIA, INC. (E

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 15, 2023 EYENOVIA, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 001-38365 47-1178401 (State or other jurisdiction of incorporation) (Commission File Num

August 16, 2023 EX-99.2

Boldly Go Where Eyecare H a s Never Gone Before August 2023

Exhibit 99.2 Boldly Go Where Eyecare H a s Never Gone Before August 2023 Forward looking statements Except for historical information, all the statements, expectations and assumptions contained in this presentation are forwar d - looking statements. Forward - looking statements include, but are not limited to, statements that express our intentions, beliefs, expectations, strategies, predictions o

August 11, 2023 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended: June 30, 2023 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to COMMISSION FILE NUMBER: 001-38365 EYENOVIA, INC.

August 10, 2023 EX-99.1

Eyenovia Reports Second Quarter 2023 Financial Results and Provides Business Update Announced FDA approval of and first commercial sale of Mydcombi™, the only fixed dose combination of tropicamide and phenylephrine for mydriasis and the first FDA app

Exhibit 99.1 Eyenovia Reports Second Quarter 2023 Financial Results and Provides Business Update Announced FDA approval of and first commercial sale of Mydcombi™, the only fixed dose combination of tropicamide and phenylephrine for mydriasis and the first FDA approved product to utilize the Optejet® Continued to advance its Phase 3 Apersure™ (Microline) presbyopia candidate following receipt of gu

August 10, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 10, 2023 EYENOVIA, INC. (E

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 10, 2023 EYENOVIA, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 001-38365 47-1178401 (State or other jurisdiction of incorporation) (Commission File Num

June 27, 2023 EX-99.1

1 Forward-looking Statements Except for historical information, all the statements, expectations and assumptions contained in this presentation are forward-looking statements. Forward-looking statements include, but are not limited to, statements tha

Exhibit 99.1 2023 Annual Meeting 1 Forward-looking Statements Except for historical information, all the statements, expectations and assumptions contained in this presentation are forward-looking statements. Forward-looking statements include, but are not limited to, statements that express our intentions, beliefs, expectations, strategies, predictions or any other statements relating to our futu

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