Ionis Pharmaceuticals, Inc.
US ˙ NasdaqGS ˙ US4622221004

Introduzione

Questa pagina fornisce un'analisi completa dello storico delle operazioni di insider trading note di Joseph Iii Klein. Gli insider sono funzionari, direttori o investitori importanti di una società. In generale, è illegale per gli insider effettuare operazioni di compravendita nelle loro aziende sulla base di informazioni materiali non pubbliche. Ciò non significa che sia illegale per loro effettuare qualsiasi operazioni di trading nelle proprie aziende. Tuttavia, devono segnalare tutte le operazioni alla SEC tramite un modulo 4. Nonostante queste restrizioni, la ricerca accademica suggerisce che gli insider, in generale, tendono a sovraperformare il mercato nelle proprie società.

Redditività media delle transazioni

La redditività media delle transazioni è il rendimento medio di tutti gli acquisti effettuati sul mercato aperto dagli insider negli ultimi tre anni. Pe calcolarla, esaminiamo tutti gli acquisti non pianificati effettuati dall'insider sul mercato aperto, escludendo tutte le operazioni che sono state parte di un piano di trading 10b5-1. Calcoliamo quindi la performance media di queste operazioni nell'arco di 3, 6 e 12 mesi e facciamo la media di ciascuna di queste durate per generare un indicatore di performance finale per ogni operazione. Infine, facciamo la media di tutti gli indicatori di performance per calcolare un indicatore di performance per l'insider. Questo elenco comprende solo gli insider che hanno effettuato almeno tre operazioni negli ultimi due anni.

Se la redditività delle operazioni di questo insider è "N/D", l'insider non ha effettuato acquisti sul mercato aperto negli ultimi tre anni, oppure le operazioni effettuate sono troppo recenti per poter calcolare un indicatore di performance affidabile.

Frequenza di aggiornamento: giornaliera

Vedi l'elenco degli insider trader più redditizi

Società con posizioni di insider dichiarate

I depositi SEC indicano che Joseph Iii Klein ha dichiarato partecipazioni o transazioni nelle seguenti società:

Titolo Ruolo Ultime partecipazioni dichiarate
US:IONS / Ionis Pharmaceuticals, Inc. Director 0
Director 0
US:69329YAE4 / PDL BioPharma, Inc. Bond 2.875% Director 16.983
Come interpretare i grafici

I grafici seguenti mostrano l'andamento dei titoli dopo ogni operazione di mercato aperto non pianificata effettuata da Joseph Iii Klein. Per operazioni non pianificate si intendono operazioni non effettuate nell'ambito di un piano di trading 10b5-1. La performance dei titoli è rappresentata come variazione percentuale cumulativa del prezzo delle azioni. Ad esempio, se un'operazione di insider è stata effettuata il 1° gennaio 2019, il grafico mostrerà la variazione percentuale giornaliera del titolo fino ad oggi. Se il prezzo dell'azione passasse da 10 a 15 dollari durante questo periodo, la variazione percentuale cumulativa del prezzo dell'azione sarebbe del 50%. Una variazione di prezzo da 10 a 20 dollari sarebbe del 100%, mentre una variazione di prezzo da 10 a 5 dollari sarebbe del -50%.

In definitiva, cerchiamo di determinare la correlazione tra le operazioni dell'insider e i rendimenti in eccesso (positivi o negativi) del prezzo dell'azione, al fine di capire se l'insider sta programmando le proprie operazioni per trarre profitto da informazioni privilegiate. Immaginiamo che un insider stia facendo questo. In questa situazione, ci aspetteremmo (a) rendimenti positivi dopo gli acquisti, oppure (b) rendimenti negativi dopo le vendite. Nel caso (a), il grafico ACQUISTO mostrerebbe una serie di curve ascendenti, indicando rendimenti positivi dopo ogni operazione di acquisto. Nel caso (b), il grafico VENDITA mostrerebbe una serie di curve inclinate verso il basso, indicando rendimenti negativi dopo ogni operazione di vendita.

Tuttavia, questo non è sufficiente per trarre conclusioni. Se, ad esempio, il prezzo delle azioni della società è aumentato in maniera non ciclica per molti anni, allora ci aspetteremmo che tutti i grafici post-acquisto abbiano una pendenza rivolta verso l'alto. Allo stesso modo, ribassi non ciclici per molti anni darebbero luogo a grafici post-negoziazione rivolti verso il basso. Nessuno di questi grafici suggerisce un'attività di insider trading.

L'indicatore più forte sarebbe una situazione in cui il prezzo delle azioni fosse estremamente ciclico e vi fossero segnali positivi nel grafico ACQUISTO e curve negative nel grafico VENDITA. Questa situazione suggerirebbe che l'insider sta programmando le operazioni di trading per trarne un vantaggio finanziario.

Acquisti di insider IONS / Ionis Pharmaceuticals, Inc. - Analisi degli utili a breve termine

In questa sezione analizziamo la redditività di ogni acquisto non pianificato di insider sul mercato aperto effettuato in IONS / Ionis Pharmaceuticals, Inc.. Questa analisi aiuta a capire se l'insider genera costantemente rendimenti anomali e se vale la pena seguirlo. L'analisi riguarda l'anno successivo a ciascuna operazione, e i risultati sono teorici.

La tabella seguente mostra gli acquisti più recenti sul mercato aperto che non facevano parte di un piano di trading automatico.

Data dell'operazione Ticker Insider Azioni
dichiarate
Prezzo
dichiarato
Azioni
rettificate
Prezzo
rettificato
Base di costo Giorni fino al
massimo
Prezzo al
massimo
Profitto
massimo ($)
Rendimento massimo (%)
Non sono note operazioni di mercato aperto non pianificate per questa combinazione di insider e titoli.

Il prezzo rettificato è il prezzo rettificato per il frazionamento azionario. Leazioni rettificate sono le azioni rettificate per il frazionamento azionario.

IONS / Ionis Pharmaceuticals, Inc. Insider Trades
Vendite di insider IONS / Ionis Pharmaceuticals, Inc. - Analisi delle perdite a breve termine

In questa sezione, analizziamo l'evitamento delle perdite a breve termine di ogni vendita di insider non pianificata ed effettuata sul mercato aperto in IONS / Ionis Pharmaceuticals, Inc.. Un modello coerente di evitamento delle perdite può suggerire che future transazioni di vendita potrebbero predire cali di prezzo. L'analisi riguarda l'anno successivo a ciascuna operazione, e i risultati sono teorici.

La tabella seguente mostra le vendite più recenti sul mercato aperto che non facevano parte di un piano di trading automatico.

Data dell'operazione Ticker Insider Azioni
dichiarate
Prezzo
dichiarato
Azioni
rettificate
Prezzo
rettificato
Base di costo Giorni fino al
minimo
Prezzo al
minimo
Perdita massima
evitata ($)
Perdita massima
evitata (%)
2024-05-03 IONS KLEIN JOSEPH III 1.318 42,5721 1.318 42,5721 56.110 340 25.5100 -22.488 -40,08
2024-05-03 IONS KLEIN JOSEPH III 682 42,9449 682 42,9449 29.288
2024-05-03 IONS KLEIN JOSEPH III 1.269 42,5875 1.269 42,5875 54.044
2024-05-03 IONS KLEIN JOSEPH III 731 42,9767 731 42,9767 31.416
2024-05-03 IONS KLEIN JOSEPH III 1.070 42,5473 1.070 42,5473 45.526
2024-05-03 IONS KLEIN JOSEPH III 930 42,8957 930 42,8957 39.893
2015-11-11 ISIS KLEIN JOSEPH III 3.750 64,1795 3.750 64,1795 240.673
2015-11-11 ISIS KLEIN JOSEPH III 3.125 64,1795 3.125 64,1795 200.561
2015-03-05 ISIS KLEIN JOSEPH III 7.000 70,9545 7.000 70,9545 496.682
2014-01-24 ISIS KLEIN JOSEPH III 7.500 48,6797 7.500 48,6797 365.098
2014-01-24 ISIS KLEIN JOSEPH III 2.813 48,6102 2.813 48,6102 136.740
2013-11-25 ISIS KLEIN JOSEPH III 6.000 36,8594 6.000 36,8594 221.156
2013-08-09 ISIS KLEIN JOSEPH III 103 28,2300 103 28,2300 2.908
2013-08-09 ISIS KLEIN JOSEPH III 3.647 28,2200 3.647 28,2200 102.918
2013-08-09 ISIS KLEIN JOSEPH III 7.500 28,2200 7.500 28,2200 211.650
2013-08-09 ISIS KLEIN JOSEPH III 7.500 28,2200 7.500 28,2200 211.650

Il prezzo rettificato è il prezzo rettificato per il frazionamento azionario. Leazioni rettificate sono le azioni rettificate per il frazionamento azionario.

IONS / Ionis Pharmaceuticals, Inc. Insider Trades
Storico delle operazioni degli insider

Questa tabella mostra l'elenco completo delle operazioni effettuate da Joseph Iii Klein come comunicato alla Securities Exchange Commission (SEC).

Data di deposito Data della transazione Modulo Ticker Titolo Codice 10b5-1 Azioni Azioni rimanenti Variazione
percentuale
Prezzo
dell'azione
Valore
della transazione
Valore
rimanente
2025-09-04 2025-09-03 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -28.000 0 -100,00 60,00 -1.680.000
2025-09-04 2025-09-03 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 12.000 28.000 75,00
2025-09-04 2025-09-03 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 16.000 16.000
2025-09-04 2025-09-03 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -28.000 0 -100,00 60,00 -1.680.000
2025-09-04 2025-09-03 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 12.000 28.000 75,00
2025-09-04 2025-09-03 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 16.000 16.000
2024-07-17 2024-07-16 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -12.000 0 -100,00 50,00 -600.000
2024-07-17 2024-07-16 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 12.000 12.000 24,42 293.040 293.040
2024-05-07 2024-05-03 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale -930 0 -100,00 42,90 -39.893
2024-05-07 2024-05-03 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale -1.070 930 -53,50 42,55 -45.526 39.569
2024-05-07 2024-05-03 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale -731 2.000 -26,77 42,98 -31.416 85.953
2024-05-07 2024-05-03 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale -1.269 2.731 -31,72 42,59 -54.044 116.306
2024-05-07 2024-05-03 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale -682 4.000 -14,57 42,94 -29.288 171.780
2024-05-07 2024-05-03 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale -1.318 4.682 -21,97 42,57 -56.110 199.323
2023-11-17 2023-11-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -2.000 16.346 -10,90 50,00 -100.000 817.300
2023-09-28 2023-09-26 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -2.000 18.346 -9,83 45,13 -90.254 827.896
2023-07-19 2023-07-18 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -3.555 20.346 -14,87 42,00 -149.310 854.532
2023-07-19 2023-07-17 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 5.333 23.901 28,72
2023-07-19 2023-07-17 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 1.777 18.568 10,58
2023-01-18 2023-01-17 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -2.000 16.791 -10,64 40,00 -80.000 671.640
2022-07-19 2022-07-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -644 18.791 -3,31 38,78 -24.974 728.715
2022-07-19 2022-07-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -689 19.435 -3,42 37,74 -26.003 733.477
2022-07-19 2022-07-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 2.665 20.124 15,26
2022-07-19 2022-07-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 5.333 17.459 43,98
2022-02-14 2021-11-30 5 IONS IONIS PHARMACEUTICALS INC
Non-Qualified Stock Option (right to buy)
G - Gift 8.000 8.000
2022-02-14 2021-11-30 5 IONS IONIS PHARMACEUTICALS INC
Non-Qualified Stock Option (right to buy)
G - Gift 12.000 12.000
2022-02-14 2021-11-30 5 IONS IONIS PHARMACEUTICALS INC
Non-Qualified Stock Option (right to buy)
G - Gift 12.000 12.000
2022-02-14 2021-11-30 5 IONS IONIS PHARMACEUTICALS INC
Non-Qualified Stock Option (right to buy)
G - Gift 16.000 16.000
2022-02-14 2021-11-30 5 IONS IONIS PHARMACEUTICALS INC
Non-Qualified Stock Option (right to buy)
G - Gift 16.000 16.000
2022-02-14 2021-11-30 5 IONS IONIS PHARMACEUTICALS INC
Non-Qualified Stock Option (right to buy)
G - Gift 12.000 12.000
2022-02-14 2021-11-30 5 IONS IONIS PHARMACEUTICALS INC
Non-Qualified Stock Option (right to buy)
G - Gift -8.000 8.000 -50,00
2022-02-14 2021-11-30 5 IONS IONIS PHARMACEUTICALS INC
Non-Qualified Stock Option (right to buy)
G - Gift -12.000 0 -100,00
2022-02-14 2021-11-30 5 IONS IONIS PHARMACEUTICALS INC
Non-Qualified Stock Option (right to buy)
G - Gift -12.000 0 -100,00
2022-02-14 2021-11-30 5 IONS IONIS PHARMACEUTICALS INC
Non-Qualified Stock Option (right to buy)
G - Gift -16.000 0 -100,00
2022-02-14 2021-11-30 5 IONS IONIS PHARMACEUTICALS INC
Non-Qualified Stock Option (right to buy)
G - Gift -16.000 0 -100,00
2022-02-14 2021-11-30 5 IONS IONIS PHARMACEUTICALS INC
Non-Qualified Stock Option (right to buy)
G - Gift -12.000 4.000 -75,00
2022-02-14 2021-11-30 5 IONS IONIS PHARMACEUTICALS INC
Common Stock
G - Gift 6.000 6.000
2022-02-14 2021-11-30 5 IONS IONIS PHARMACEUTICALS INC
Common Stock
G - Gift -6.000 12.126 -33,10
2021-07-19 2021-07-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Unit
M - Exercise -1.778 9.775 -15,39
2021-07-19 2021-07-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Unit
M - Exercise -666 11.553 -5,45
2021-07-19 2021-07-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Unit
M - Exercise -889 12.219 -6,78
2021-07-19 2021-07-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Unit
M - Exercise -5.333 13.108 -28,92
2021-07-19 2021-07-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -4.334 18.126 -19,30 35,30 -152.989 639.844
2021-07-19 2021-07-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 1.778 22.460 8,60
2021-07-19 2021-07-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 666 20.682 3,33
2021-07-19 2021-07-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 889 20.016 4,65
2021-07-19 2021-07-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 5.333 19.127 38,66
2021-07-06 2021-07-01 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Unit
A - Award 5.333 18.441 40,69
2021-07-06 2021-07-01 4 IONS IONIS PHARMACEUTICALS INC
Non-Qualified Stock Option (right to buy)
A - Award 12.000 12.000
2020-10-22 2020-10-20 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -2.889 13.794 -17,32 46,86 -135.386 646.421
2020-10-13 2020-10-12 4 AKCA AKCEA THERAPEUTICS, INC.
Stock Option (right to buy)
D - Sale to Issuer -26.400 0 -100,00 2,01 -53.064
2020-07-06 2020-07-06 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -667 666 -50,04
2020-07-06 2020-07-06 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 667 16.683 4,16
2020-07-06 2020-07-02 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -889 1.777 -33,35
2020-07-06 2020-07-02 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 889 16.016 5,88
2020-07-06 2020-07-01 4 IONS IONIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
A - Award 12.000 12.000
2020-07-06 2020-07-01 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 5.333 5.333
2020-07-06 2020-07-01 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -1.778 5.332 -25,01
2020-07-06 2020-07-01 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -666 0 -100,00
2020-07-06 2020-07-01 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 1.778 15.127 13,32
2020-07-06 2020-07-01 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 666 13.349 5,25
2020-04-15 2020-04-13 4 AKCA AKCEA THERAPEUTICS, INC.
Stock Option (right to buy)
A - Award 26.400 26.400
2019-12-23 2019-12-23 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -1.000 0 -100,00
2019-12-23 2019-12-23 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -1.000 12.683 -7,31 61,87 -61.874 784.750
2019-12-23 2019-12-23 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1.000 13.683 7,88 35,53 35.530 486.157
2019-12-18 2019-12-16 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -1.000 1.000 -50,00
2019-12-18 2019-12-16 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -1.000 12.683 -7,31 65,45 -65.446 830.058
2019-12-18 2019-12-16 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1.000 13.683 7,88 35,53 35.530 486.157
2019-12-10 2019-12-09 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -1.000 2.000 -33,33
2019-12-10 2019-12-09 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -1.000 12.683 -7,31 63,74 -63.745 808.474
2019-12-10 2019-12-09 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1.000 13.683 7,88 35,53 35.530 486.157
2019-12-04 2019-12-02 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -1.000 3.000 -25,00
2019-12-04 2019-12-02 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -1.000 12.683 -7,31 64,08 -64.083 812.765
2019-12-04 2019-12-02 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1.000 13.683 7,88 35,53 35.530 486.157
2019-11-26 2019-11-25 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -812 12.683 -6,02 62,90 -51.075 797.761
2019-11-21 2019-11-20 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -2.000 13.495 -12,91 60,00 -120.000 809.700
2019-09-23 2019-09-20 4 AKCA AKCEA THERAPEUTICS, INC.
Stock Option (right to buy)
A - Award 53.000 53.000
2019-07-03 2019-07-03 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -667 1.333 -33,35
2019-07-03 2019-07-03 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 667 15.495 4,50
2019-07-03 2019-07-02 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -889 2.666 -25,01
2019-07-03 2019-07-02 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 889 14.828 6,38
2019-07-03 2019-07-01 4 IONS IONIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
A - Award 16.000 16.000
2019-07-03 2019-07-01 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 7.110 7.110
2019-07-03 2019-07-01 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -667 666 -50,04
2019-07-03 2019-07-01 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -666 0 -100,00
2019-07-03 2019-07-01 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 667 13.939 5,03
2019-07-03 2019-07-01 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 666 13.272 5,28
2018-07-03 2018-07-03 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -667 2.000 -25,01
2018-07-03 2018-07-03 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 667 12.606 5,59
2018-07-03 2018-07-02 4 IONS IONIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
A - Award 16.000 16.000
2018-07-03 2018-07-02 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 3.555 3.555
2018-07-03 2018-07-01 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -2.000 1.999 -50,01
2018-07-03 2018-07-01 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 2.000 11.939 20,12
2018-03-30 2018-03-29 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise 2.000 0 -100,00
2018-03-30 2018-03-29 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -2.000 9.939 -16,75 46,15 -92.300 458.685
2018-03-30 2018-03-29 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 2.000 11.939 20,12 24,42 48.840 291.550
2018-03-16 2018-03-15 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise 2.000 2.000
2018-03-16 2018-03-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -200 9.939 -1,97 52,11 -10.422 517.921
2018-03-16 2018-03-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 200 10.139 2,01 24,42 4.884 247.594
2018-03-16 2018-03-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -900 9.939 -8,30 51,59 -46.431 512.753
2018-03-16 2018-03-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 900 10.839 9,06 24,42 21.978 264.688
2018-03-16 2018-03-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 900 10.839 9,06 24,42 21.978 264.688
2018-03-16 2018-03-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -900 9.939 -8,30 50,45 -45.405 501.423
2018-03-01 2018-02-28 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise 3.000 0 -100,00
2018-03-01 2018-02-28 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -2.100 9.939 -17,44 52,29 -109.809 519.710
2018-03-01 2018-02-28 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 2.100 12.039 21,13 35,53 74.613 427.746
2018-03-01 2018-02-28 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -900 9.939 -8,30 51,02 -45.918 507.088
2018-03-01 2018-02-28 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 900 10.839 9,06 35,53 31.977 385.110
2018-02-16 2018-02-15 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise 3.000 3.000
2018-02-16 2018-02-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -1.600 9.939 -13,87 49,20 -78.720 488.999
2018-02-16 2018-02-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1.600 11.539 16,10 35,53 56.848 409.981
2018-02-16 2018-02-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -1.400 9.939 -12,35 48,76 -68.264 484.626
2018-02-16 2018-02-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1.400 11.339 14,09 35,53 49.742 402.875
2018-01-31 2018-01-30 4/A IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise 3.000 6.000 100,00
2018-01-31 2018-01-30 4/A IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -3.000 9.939 -23,19 52,86 -158.580 525.376
2018-01-31 2018-01-30 4/A IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 3.000 12.939 30,18 35,53 106.590 459.723
2018-01-17 2018-01-16 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -3.000 9.000 -25,00
2018-01-17 2018-01-16 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -1.400 9.939 -12,35 52,97 -74.158 526.469
2018-01-17 2018-01-16 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1.400 11.339 14,09 35,53 49.742 402.875
2018-01-17 2018-01-16 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -1.600 9.939 -13,87 52,13 -83.408 518.120
2018-01-17 2018-01-16 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1.600 11.539 16,10 35,53 56.848 409.981
2018-01-02 2017-12-29 4 IONS IONIS PHARMACEUTICALS INC
Non-Employee Director Stock Option (right to buy)
M - Exercise -3.000 0 -100,00
2018-01-02 2017-12-29 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -3.000 9.939 -23,19 50,56 -151.680 502.516
2018-01-02 2017-12-29 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 3.000 12.939 30,18 28,47 85.410 368.373
2017-12-19 2017-12-15 4 IONS IONIS PHARMACEUTICALS INC
NonEmployee Director stock option (right to buy)
M - Exercise -3.000 3.000 -50,00
2017-12-19 2017-12-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -3.000 9.939 -23,19 51,69 -155.070 513.747
2017-12-19 2017-12-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 3.000 12.939 30,18 28,47 85.410 368.373
2017-12-01 2017-11-30 4 IONS IONIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -3.000 6.000 -33,33
2017-12-01 2017-11-30 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -3.000 9.939 -23,19 53,55 -160.650 532.233
2017-12-01 2017-11-30 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 3.000 12.939 30,18 28,47 85.410 368.373
2017-11-17 2017-11-16 4 IONS IONIS PHARMACEUTICALS INC
Non-Employee Director Stock Option (right to buy)
M - Exercise -2.812 0 -100,00
2017-11-17 2017-11-16 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 2.812 9.939 39,46 12,94 36.387 128.611
2017-11-17 2017-11-15 4 IONS IONIS PHARMACEUTICALS INC
Non-Employee Director Stock Option (right to buy)
M - Exercise -2.250 9.000 -20,00
2017-11-17 2017-11-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -2.250 7.127 -23,99 53,56 -120.510 381.722
2017-11-17 2017-11-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 2.250 9.377 31,57 28,47 64.058 266.963
2017-11-14 2017-11-13 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -3.000 7.127 -29,62 55,39 -166.170 394.765
2017-07-03 2017-07-03 4 IONS IONIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
A - Award 16.000 16.000
2017-07-03 2017-07-03 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 2.667 2.667
2017-07-03 2017-07-02 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 2.469 10.127 32,24
2017-07-03 2017-07-01 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -2.469 3.999 -38,17
2016-07-06 2016-07-02 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -312 0 -100,00
2016-07-06 2016-07-02 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 312 7.658 4,25
2016-07-06 2016-07-01 4 IONS IONIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
A - Award 16.000 16.000
2016-07-06 2016-07-01 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 2.667 2.667
2016-07-06 2016-07-01 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -1.803 3.801 -32,17
2016-07-06 2016-07-01 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 469 7.346 6,82
2016-07-06 2016-07-01 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 667 6.877 10,74
2016-07-06 2016-07-01 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 667 6.877 10,74
2015-11-12 2015-11-11 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -3.125 2.812 -52,64
2015-11-12 2015-11-11 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -3.750 0 -100,00
2015-11-12 2015-11-11 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale -3.125 5.543 -36,05 64,18 -200.561 355.747
2015-11-12 2015-11-11 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 3.125 8.668 56,38 12,94 40.438 112.164
2015-11-12 2015-11-11 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale -3.750 5.543 -40,35 64,18 -240.673 355.747
2015-11-12 2015-11-11 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 3.750 9.293 67,65 9,30 34.875 86.425
2015-07-02 2015-07-02 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -312 312 -50,00
2015-07-02 2015-07-02 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 312 5.543 5,96
2015-07-02 2015-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
A - Award 16.000 16.000
2015-07-02 2015-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 2.667 2.667
2015-07-02 2015-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -667 2.000 -25,01
2015-07-02 2015-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -469 937 -33,36
2015-07-02 2015-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 667 5.231 14,61
2015-07-02 2015-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 469 4.564 11,45
2015-03-09 2015-03-05 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -2.500 5.937 -29,63
2015-03-09 2015-03-05 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -3.750 3.750 -50,00
2015-03-09 2015-03-05 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -3.750 3.750 -50,00
2015-03-09 2015-03-05 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale -7.000 4.095 -63,09 70,95 -496.682 290.559
2015-03-09 2015-03-05 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 2.500 11.095 29,09 12,94 32.350 143.569
2015-03-09 2015-03-05 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 3.750 8.595 77,40 9,30 34.875 79.934
2015-03-09 2015-03-05 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 3.750 4.845 342,47 9,22 34.575 44.671
2015-02-13 2015-02-11 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
G - Gift -2.000 1.095 -64,62
2014-07-02 2014-07-02 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -313 624 -33,40
2014-07-02 2014-07-02 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 313 3.095 11,25
2014-07-02 2014-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
A - Award 16.000 16.000
2014-07-02 2014-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 2.667 2.667
2014-07-02 2014-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -469 1.406 -25,01
2014-07-02 2014-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 469 2.782 20,28
2014-01-24 2014-01-24 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -2.813 8.437 -25,00
2014-01-24 2014-01-24 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -7.500 0 -100,00
2014-01-24 2014-01-24 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale -2.813 2.313 -54,88 48,61 -136.740 112.435
2014-01-24 2014-01-24 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 2.813 5.126 121,62 12,94 36.400 66.330
2014-01-24 2014-01-24 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale -7.500 2.313 -76,43 48,68 -365.098 112.596
2014-01-24 2014-01-24 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 7.500 9.813 324,25 16,32 122.400 160.148
2013-11-27 2013-11-25 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale -6.000 2.313 -72,18 36,86 -221.156 85.256
2013-08-13 2013-08-09 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -7.500 7.500 -50,00
2013-08-13 2013-08-09 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -7.500 7.500 -50,00
2013-08-13 2013-08-09 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -3.750 0 -100,00
2013-08-13 2013-08-09 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale -7.500 8.313 -47,43 28,22 -211.650 234.593
2013-08-13 2013-08-09 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale -7.500 8.313 -47,43 28,22 -211.650 234.593
2013-08-13 2013-08-09 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 7.500 15.813 90,22 9,22 69.150 145.796
2013-08-13 2013-08-09 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 7.500 15.813 90,22 9,30 69.750 147.061
2013-08-13 2013-08-09 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale -3.647 8.313 -30,49 28,22 -102.918 234.593
2013-08-13 2013-08-09 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 3.647 11.960 43,87 13,88 50.620 166.005
2013-08-13 2013-08-09 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale -103 8.313 -1,22 28,23 -2.908 234.676
2013-08-13 2013-08-09 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 103 8.416 1,24 13,88 1.430 116.814
2013-07-03 2013-07-02 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -313 937 -25,04
2013-07-03 2013-07-02 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 313 8.313 3,91
2013-07-03 2013-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 1.875 1.875
2013-07-03 2013-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
A - Award 11.250 11.250
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -174 0 -100,00 18,00 -3.132
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 174 174 5,93 1.032 1.032
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -1.250 0 -100,00 18,00 -22.500
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1.250 1.250 9,22 11.525 11.525
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -2.500 0 -100,00 18,00 -45.000
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 2.500 2.500 16,32 40.800 40.800
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -174 0 -100,00
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -174 0 -100,00
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -1.250 0 -100,00
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -1.250 0 -100,00
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -2.500 0 -100,00
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -2.500 0 -100,00
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -4.167 0 -100,00
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -4.167 0 -100,00
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -3.750 0 -100,00
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -3.750 0 -100,00
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -1.250 0 -100,00
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -2.500 0 -100,00
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -3.750 0 -100,00
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -173 0 -100,00
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -4.166 0 -100,00
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -4.167 0 -100,00 18,00 -75.006
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -4.167 0 -100,00 18,00 -75.006
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 4.167 4.167 9,77 40.712 40.712
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 4.167 4.167 9,77 40.712 40.712
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -3.750 0 -100,00 18,00 -67.500
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 3.750 3.750 13,88 52.050 52.050
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -174 0 -100,00 18,00 -3.132
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 174 174 5,93 1.032 1.032
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -1.250 0 -100,00 18,00 -22.500
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -1.250 0 -100,00 18,00 -22.500
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1.250 1.250 9,22 11.525 11.525
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1.250 1.250 9,22 11.525 11.525
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -2.500 0 -100,00 18,00 -45.000
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 2.500 2.500 16,32 40.800 40.800
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -3.750 0 -100,00 18,00 -67.500
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 3.750 3.750 13,88 52.050 52.050
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -173 100 -63,37 18,00 -3.114 1.800
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 173 273 173,00 5,93 1.026 1.619
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -2.500 100 -96,15 18,00 -45.000 1.800
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 2.500 2.600 2.500,00 16,32 40.800 42.432
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -4.166 100 -97,66 18,00 -74.988 1.800
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 4.166 4.266 4.166,00 9,77 40.702 41.679
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -3.750 100 -97,40 18,00 -67.500 1.800
2013-03-21 2013-03-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 3.750 3.850 3.750,00 13,88 52.050 53.438
2013-03-21 2013-03-19 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -3.727 174 -95,54
2013-03-21 2013-03-19 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -3.726 174 -95,54
2013-03-21 2013-03-19 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -3.726 174 -95,54
2013-03-21 2013-03-19 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -3.727 0 -100,00 18,00 -67.086
2013-03-21 2013-03-19 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 3.727 3.727 5,93 22.101 22.101
2013-03-21 2013-03-19 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -3.726 0 -100,00 18,00 -67.068
2013-03-21 2013-03-19 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -3.726 0 -100,00 18,00 -67.068
2013-03-21 2013-03-19 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 3.726 3.726 5,93 22.095 22.095
2013-03-21 2013-03-19 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 3.726 3.726 5,93 22.095 22.095
2013-03-14 2013-03-13 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -6.667 0 -100,00
2013-03-14 2013-03-13 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -6.667 0 -100,00
2013-03-14 2013-03-13 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -266 3.901 -6,38
2013-03-14 2013-03-13 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -266 3.901 -6,38
2013-03-14 2013-03-13 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -6.666 0 -100,00
2013-03-14 2013-03-13 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -268 3.899 -6,43
2013-03-14 2013-03-13 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -6.667 0 -100,00 18,01 -120.052
2013-03-14 2013-03-13 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -6.667 0 -100,00 18,01 -120.052
2013-03-14 2013-03-13 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 6.667 6.667 5,17 34.468 34.468
2013-03-14 2013-03-13 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 6.667 6.667 5,17 34.468 34.468
2013-03-14 2013-03-13 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -266 0 -100,00 18,01 -4.790
2013-03-14 2013-03-13 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -266 0 -100,00 18,01 -4.790
2013-03-14 2013-03-13 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 266 266 5,93 1.577 1.577
2013-03-14 2013-03-13 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 266 266 5,93 1.577 1.577
2013-03-14 2013-03-13 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -6.666 100 -98,52 18,01 -120.034 1.801
2013-03-14 2013-03-13 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 6.666 6.766 6.666,00 5,17 34.463 34.980
2013-03-14 2013-03-13 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -268 100 -72,83 18,01 -4.826 1.801
2013-03-14 2013-03-13 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 268 368 268,00 5,93 1.589 2.182
2012-07-03 2012-07-02 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
A - Award 11.250 11.250
2012-07-03 2012-07-02 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 1.250 1.250
2012-01-05 2012-01-04 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
G - Gift 1.250 1.250
2012-01-05 2012-01-04 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
G - Gift 1.250 1.250
2012-01-05 2012-01-04 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
G - Gift 2.500 2.500
2012-01-05 2012-01-04 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
G - Gift 2.500 2.500
2012-01-05 2012-01-04 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
G - Gift 3.750 3.750
2012-01-05 2012-01-04 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
G - Gift 3.750 3.750
2012-01-05 2012-01-04 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
G - Gift 4.167 4.167
2012-01-05 2012-01-04 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
G - Gift 4.167 4.167
2012-01-05 2012-01-04 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
G - Gift 1.250 1.250
2012-01-05 2012-01-04 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
G - Gift 2.500 2.500
2012-01-05 2012-01-04 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
G - Gift 3.750 3.750
2012-01-05 2012-01-04 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
G - Gift 4.166 4.166
2012-01-05 2012-01-04 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
G - Gift -3.750 11.250 -25,00
2012-01-05 2012-01-04 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
G - Gift -7.500 7.500 -50,00
2012-01-05 2012-01-04 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
G - Gift -11.250 3.750 -75,00
2012-01-05 2012-01-04 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
G - Gift -12.500 0 -100,00
2012-01-03 2011-12-30 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
G - Gift 4.167 4.167
2012-01-03 2011-12-30 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
G - Gift 4.167 4.167
2012-01-03 2011-12-30 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
G - Gift 6.667 6.667
2012-01-03 2011-12-30 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
G - Gift 6.667 6.667
2012-01-03 2011-12-30 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
G - Gift 4.166 4.166
2012-01-03 2011-12-30 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
G - Gift 6.666 6.666
2012-01-03 2011-12-30 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
G - Gift -12.500 0 -100,00
2012-01-03 2011-12-30 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
G - Gift -20.000 0 -100,00
2009-06-08 2009-06-04 4 PDLI PDL BIOPHARMA, INC.
Common Stock
A - Award 6.983 16.983 69,83 7,16 49.998 121.598
2007-09-10 2007-09-06 4 PDLI PDL BIOPHARMA, INC.
Commn Stock
P - Purchase X 500 1.500 50,00 20,12 10.060 30.180
2005-12-15 3 ISIS ISIS PHARMACEUTICALS INC
Common Stock
100
P
Acquisto sul mercato aperto o privato di un titolo non derivato o derivato
S
Vendita sul mercato aperto o privato di un titolo non derivato o derivato
A
Concessione, assegnazione o altra acquisizione di titoli dall'azienda (ad esempio un'opzione)
C
Conversione di un derivato
D
Vendita o trasferimento di titoli alla società
F
Pagamento del prezzo di esercizio o del debito fiscale con la quota di titoli ricevuta dalla società
G
Regalo di titoli da parte o a favore dell'insider
K
Equity swap e operazioni di copertura analoghe
M
Esercizio o conversione di un titolo derivato ricevuto dall'azienda (ad esempio un'opzione)
V
Una transazione dichiarata volontariamente sul modulo 4
J
Altro (accompagnato da una nota a piè di pagina che descriva l'operazione)