Ionis Pharmaceuticals, Inc.
US ˙ NasdaqGS ˙ US4622221004

Introduzione

Questa pagina fornisce un'analisi completa dello storico delle operazioni di insider trading note di Richard S Geary. Gli insider sono funzionari, direttori o investitori importanti di una società. In generale, è illegale per gli insider effettuare operazioni di compravendita nelle loro aziende sulla base di informazioni materiali non pubbliche. Ciò non significa che sia illegale per loro effettuare qualsiasi operazioni di trading nelle proprie aziende. Tuttavia, devono segnalare tutte le operazioni alla SEC tramite un modulo 4. Nonostante queste restrizioni, la ricerca accademica suggerisce che gli insider, in generale, tendono a sovraperformare il mercato nelle proprie società.

Redditività media delle transazioni

La redditività media delle transazioni è il rendimento medio di tutti gli acquisti effettuati sul mercato aperto dagli insider negli ultimi tre anni. Pe calcolarla, esaminiamo tutti gli acquisti non pianificati effettuati dall'insider sul mercato aperto, escludendo tutte le operazioni che sono state parte di un piano di trading 10b5-1. Calcoliamo quindi la performance media di queste operazioni nell'arco di 3, 6 e 12 mesi e facciamo la media di ciascuna di queste durate per generare un indicatore di performance finale per ogni operazione. Infine, facciamo la media di tutti gli indicatori di performance per calcolare un indicatore di performance per l'insider. Questo elenco comprende solo gli insider che hanno effettuato almeno tre operazioni negli ultimi due anni.

Se la redditività delle operazioni di questo insider è "N/D", l'insider non ha effettuato acquisti sul mercato aperto negli ultimi tre anni, oppure le operazioni effettuate sono troppo recenti per poter calcolare un indicatore di performance affidabile.

Frequenza di aggiornamento: giornaliera

Vedi l'elenco degli insider trader più redditizi

Società con posizioni di insider dichiarate

I depositi SEC indicano che Richard S Geary ha dichiarato partecipazioni o transazioni nelle seguenti società:

Titolo Ruolo Ultime partecipazioni dichiarate
US:IONS / Ionis Pharmaceuticals, Inc. EVP, Chief Development Officer 59.657
Come interpretare i grafici

I grafici seguenti mostrano l'andamento dei titoli dopo ogni operazione di mercato aperto non pianificata effettuata da Richard S Geary. Per operazioni non pianificate si intendono operazioni non effettuate nell'ambito di un piano di trading 10b5-1. La performance dei titoli è rappresentata come variazione percentuale cumulativa del prezzo delle azioni. Ad esempio, se un'operazione di insider è stata effettuata il 1° gennaio 2019, il grafico mostrerà la variazione percentuale giornaliera del titolo fino ad oggi. Se il prezzo dell'azione passasse da 10 a 15 dollari durante questo periodo, la variazione percentuale cumulativa del prezzo dell'azione sarebbe del 50%. Una variazione di prezzo da 10 a 20 dollari sarebbe del 100%, mentre una variazione di prezzo da 10 a 5 dollari sarebbe del -50%.

In definitiva, cerchiamo di determinare la correlazione tra le operazioni dell'insider e i rendimenti in eccesso (positivi o negativi) del prezzo dell'azione, al fine di capire se l'insider sta programmando le proprie operazioni per trarre profitto da informazioni privilegiate. Immaginiamo che un insider stia facendo questo. In questa situazione, ci aspetteremmo (a) rendimenti positivi dopo gli acquisti, oppure (b) rendimenti negativi dopo le vendite. Nel caso (a), il grafico ACQUISTO mostrerebbe una serie di curve ascendenti, indicando rendimenti positivi dopo ogni operazione di acquisto. Nel caso (b), il grafico VENDITA mostrerebbe una serie di curve inclinate verso il basso, indicando rendimenti negativi dopo ogni operazione di vendita.

Tuttavia, questo non è sufficiente per trarre conclusioni. Se, ad esempio, il prezzo delle azioni della società è aumentato in maniera non ciclica per molti anni, allora ci aspetteremmo che tutti i grafici post-acquisto abbiano una pendenza rivolta verso l'alto. Allo stesso modo, ribassi non ciclici per molti anni darebbero luogo a grafici post-negoziazione rivolti verso il basso. Nessuno di questi grafici suggerisce un'attività di insider trading.

L'indicatore più forte sarebbe una situazione in cui il prezzo delle azioni fosse estremamente ciclico e vi fossero segnali positivi nel grafico ACQUISTO e curve negative nel grafico VENDITA. Questa situazione suggerirebbe che l'insider sta programmando le operazioni di trading per trarne un vantaggio finanziario.

Acquisti di insider IONS / Ionis Pharmaceuticals, Inc. - Analisi degli utili a breve termine

In questa sezione analizziamo la redditività di ogni acquisto non pianificato di insider sul mercato aperto effettuato in IONS / Ionis Pharmaceuticals, Inc.. Questa analisi aiuta a capire se l'insider genera costantemente rendimenti anomali e se vale la pena seguirlo. L'analisi riguarda l'anno successivo a ciascuna operazione, e i risultati sono teorici.

La tabella seguente mostra gli acquisti più recenti sul mercato aperto che non facevano parte di un piano di trading automatico.

Data dell'operazione Ticker Insider Azioni
dichiarate
Prezzo
dichiarato
Azioni
rettificate
Prezzo
rettificato
Base di costo Giorni fino al
massimo
Prezzo al
massimo
Profitto
massimo ($)
Rendimento massimo (%)
Non sono note operazioni di mercato aperto non pianificate per questa combinazione di insider e titoli.

Il prezzo rettificato è il prezzo rettificato per il frazionamento azionario. Leazioni rettificate sono le azioni rettificate per il frazionamento azionario.

IONS / Ionis Pharmaceuticals, Inc. Insider Trades
Vendite di insider IONS / Ionis Pharmaceuticals, Inc. - Analisi delle perdite a breve termine

In questa sezione, analizziamo l'evitamento delle perdite a breve termine di ogni vendita di insider non pianificata ed effettuata sul mercato aperto in IONS / Ionis Pharmaceuticals, Inc.. Un modello coerente di evitamento delle perdite può suggerire che future transazioni di vendita potrebbero predire cali di prezzo. L'analisi riguarda l'anno successivo a ciascuna operazione, e i risultati sono teorici.

La tabella seguente mostra le vendite più recenti sul mercato aperto che non facevano parte di un piano di trading automatico.

Data dell'operazione Ticker Insider Azioni
dichiarate
Prezzo
dichiarato
Azioni
rettificate
Prezzo
rettificato
Base di costo Giorni fino al
minimo
Prezzo al
minimo
Perdita massima
evitata ($)
Perdita massima
evitata (%)
2025-11-03 IONS Geary Richard S 775 75,0540 775 75,0540 58.167 7 69.5400 -4.272 -7,35
2025-11-03 IONS Geary Richard S 905 75,0540 905 75,0540 67.924
2025-01-31 IONS Geary Richard S 1.406 32,4049 1.406 32,4049 45.561
2025-01-16 IONS Geary Richard S 7.072 32,8630 7.072 32,8630 232.407
2024-02-02 IONS Geary Richard S 1.961 50,0433 1.961 50,0433 98.135
2024-02-02 IONS Geary Richard S 1.995 50,0433 1.995 50,0433 99.836
2024-01-17 IONS Geary Richard S 7.338 50,4170 7.338 50,4170 369.960
2023-12-21 IONS Geary Richard S 4.112 49,2901 4.112 49,2901 202.681
2023-12-20 IONS Geary Richard S 6.500 49,6374 6.500 49,6374 322.643
2023-12-14 IONS Geary Richard S 6.571 49,2133 6.571 49,2133 323.381
2023-12-14 IONS Geary Richard S 4.042 50,1870 4.042 50,1870 202.856
2023-02-06 IONS Geary Richard S 1.920 40,6615 1.920 40,6615 78.070
2023-01-18 IONS Geary Richard S 7.873 39,5688 7.873 39,5688 311.525
2018-01-16 IONS Geary Richard S 2.723 51,7600 2.723 51,7600 140.942
2017-01-17 IONS Geary Richard S 546 46,2910 546 46,2910 25.275
2017-01-17 IONS Geary Richard S 733 46,2910 733 46,2910 33.931
2017-01-17 IONS Geary Richard S 539 46,2900 539 46,2900 24.950
2017-01-17 IONS Geary Richard S 623 46,2910 623 46,2910 28.839
2016-01-19 IONS Geary Richard S 309 41,4559 309 41,4559 12.810
2016-01-19 IONS Geary Richard S 556 41,4674 556 41,4674 23.056
2016-01-19 IONS Geary Richard S 747 41,4554 747 41,4554 30.967
2016-01-19 IONS Geary Richard S 550 41,4573 550 41,4573 22.802
2015-01-16 ISIS Geary Richard S 296 67,9640 296 67,9640 20.117
2015-01-16 ISIS Geary Richard S 533 67,9640 533 67,9640 36.225
2015-01-16 ISIS Geary Richard S 714 67,9640 714 67,9640 48.526
2014-01-16 ISIS Geary Richard S 296 47,0813 296 47,0813 13.936
2014-01-16 ISIS Geary Richard S 533 47,0813 533 47,0813 25.094
2013-01-16 ISIS Geary Richard S 345 14,0000 345 14,0000 4.830

Il prezzo rettificato è il prezzo rettificato per il frazionamento azionario. Leazioni rettificate sono le azioni rettificate per il frazionamento azionario.

IONS / Ionis Pharmaceuticals, Inc. Insider Trades
Storico delle operazioni degli insider

Questa tabella mostra l'elenco completo delle operazioni effettuate da Richard S Geary come comunicato alla Securities Exchange Commission (SEC).

Data di deposito Data della transazione Modulo Ticker Titolo Codice 10b5-1 Azioni Azioni rimanenti Variazione
percentuale
Prezzo
dell'azione
Valore
della transazione
Valore
rimanente
2025-11-07 2025-11-06 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -18.300 59.657 -23,47 75,42 -1.380.204 4.499.391
2025-11-07 2025-11-06 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 18.300 77.957 30,68 60,89 1.114.287 4.746.802
2025-11-07 2025-11-06 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -14.738 59.657 -19,81 76,10 -1.121.521 4.539.731
2025-11-07 2025-11-06 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 14.738 74.395 24,70 56,78 836.824 4.224.148
2025-11-07 2025-11-05 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -801 59.657 -1,32 75,01 -60.083 4.474.872
2025-11-07 2025-11-05 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 801 60.458 1,34 60,89 48.773 3.681.288
2025-11-07 2025-11-05 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -800 59.657 -1,32 75,01 -60.008 4.474.872
2025-11-07 2025-11-05 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 800 60.457 1,34 56,78 45.424 3.432.748
2025-11-07 2025-11-03 4/A IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale -905 59.657 -1,49 75,05 -67.924 4.477.496
2025-11-07 2025-11-03 4/A IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 905 60.562 1,52 56,78 51.386 3.438.710
2025-11-07 2025-11-03 4/A IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale -775 59.657 -1,28 75,05 -58.167 4.477.496
2025-11-07 2025-11-03 4/A IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 775 60.432 1,30 60,89 47.190 3.679.704
2025-11-03 2025-11-03 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -905 59.657 -1,49 75,05 -67.924 4.477.496
2025-11-03 2025-11-03 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 905 60.562 1,52 60,89 55.105 3.687.620
2025-11-03 2025-11-03 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -775 59.657 -1,28 75,05 -58.167 4.477.496
2025-11-03 2025-11-03 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 775 60.432 1,30 56,78 44.004 3.431.329
2025-11-03 2025-10-31 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -20.000 59.657 -25,11 75,11 -1.502.166 4.480.736
2025-11-03 2025-10-31 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -34.664 79.657 -30,32 75,11 -2.603.554 5.982.902
2025-11-03 2025-10-31 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 34.664 114.321 43,52 56,78 1.968.222 6.491.146
2025-11-03 2025-10-31 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -34.585 79.657 -30,27 75,11 -2.597.621 5.982.902
2025-11-03 2025-10-31 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 34.585 114.242 43,42 60,89 2.105.881 6.956.195
2025-10-01 2025-09-30 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -57.900 79.657 -42,09 65,24 -3.777.668 5.197.197
2025-10-01 2025-09-30 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 57.900 137.557 72,69 53,77 3.113.283 7.396.440
2025-09-04 2025-09-02 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -10.000 79.657 -11,15 50,37 -503.671 4.012.092
2025-09-03 2025-08-29 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
J - Other 165 89.657 0,18 27,71 4.572 2.484.395
2025-08-06 2025-08-05 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -10.000 89.492 -10,05 42,86 -428.593 3.835.564
2025-03-04 2025-02-28 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
J - Other 415 99.492 0,42 28,21 11.708 2.806.819
2025-02-03 2025-01-31 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale -1.406 99.077 -1,40 32,40 -45.561 3.210.580
2025-02-03 2025-01-30 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
A - Award 3.820 100.483 3,95
2025-01-17 2025-01-16 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale -7.072 96.663 -6,82 32,86 -232.407 3.176.636
2025-01-17 2025-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 18.901 103.735 22,28
2024-09-04 2024-02-02 4/A IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale -1.995 87.300 -2,23 50,04 -99.836 4.368.780
2024-09-04 2024-08-30 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
J - Other 11 84.834 0,01 38,64 425 3.278.071
2024-09-03 2024-08-29 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -331 84.823 -0,39 49,63 -16.428 4.209.765
2024-09-03 2024-08-28 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -320 85.154 -0,37 49,16 -15.731 4.186.171
2024-08-06 2024-08-05 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -2.430 85.508 -2,76 48,00 -116.640 4.104.384
2024-03-04 2024-02-29 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
J - Other 604 87.938 0,69 34,42 20.793 3.027.266
2024-02-02 2024-02-02 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale -1.961 87.334 -2,20 50,04 -98.135 4.370.482
2024-02-02 2024-02-01 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
A - Award 3.820 89.295 4,47
2024-01-18 2024-01-17 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale -7.338 85.475 -7,91 50,42 -369.960 4.309.393
2024-01-18 2024-01-16 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 19.852 92.813 27,21
2023-12-22 2023-12-21 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale -4.112 72.961 -5,34 49,29 -202.681 3.596.255
2023-12-22 2023-12-21 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 4.112 77.073 5,64 47,34 194.662 3.648.636
2023-12-22 2023-12-20 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale -6.500 72.961 -8,18 49,64 -322.643 3.621.594
2023-12-22 2023-12-20 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 6.500 79.461 8,91 47,34 307.710 3.761.684
2023-12-18 2023-12-14 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale -4.042 72.961 -5,25 50,19 -202.856 3.661.694
2023-12-18 2023-12-14 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 4.042 77.003 5,54 47,34 191.348 3.645.322
2023-12-18 2023-12-14 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale -6.571 72.961 -8,26 49,21 -323.381 3.590.652
2023-12-18 2023-12-14 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 6.571 79.532 9,01 47,34 311.071 3.765.045
2023-09-05 2023-08-31 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
J - Other 1 72.961 0,00 30,56 31 2.229.506
2023-03-02 2023-02-28 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
J - Other 575 72.960 0,79 30,52 17.546 2.226.374
2023-02-07 2023-02-06 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale -1.920 72.385 -2,58 40,66 -78.070 2.943.283
2023-02-07 2023-02-03 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
A - Award 3.822 74.305 5,42
2023-01-19 2023-01-18 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale -7.873 70.483 -10,05 39,57 -311.525 2.788.928
2023-01-19 2023-01-17 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 21.983 78.356 39,00
2022-03-02 2022-02-28 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
J - Other 621 56.373 1,11 28,37 17.620 1.599.471
2022-01-20 2022-01-18 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Unit
M - Exercise -21.391 50.853 -29,61
2022-01-20 2022-01-18 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
F - Taxes -7.605 55.752 -12,00 30,12 -229.063 1.679.250
2022-01-20 2022-01-18 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 21.391 63.357 50,97
2022-01-19 2022-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Unit
A - Award 15.284 72.244 26,83
2022-01-19 2022-01-15 4 IONS IONIS PHARMACEUTICALS INC
Performance Restricted Stock Units
A - Award 11.463 11.463
2022-01-05 2022-01-03 4 IONS IONIS PHARMACEUTICALS INC
Non-Qualified Stock Option (right to buy)
A - Award 30.567 30.567
2021-09-02 2021-08-31 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
J - Other 46 41.966 0,11 33,80 1.555 1.418.283
2021-03-02 2021-02-26 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
J - Other 414 41.920 1,00 44,54 18.440 1.867.117
2021-01-20 2021-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -17.598 34.246 -33,94
2021-01-20 2021-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 22.714 22.714
2021-01-20 2021-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
F - Taxes -6.398 41.506 -13,36 61,28 -392.069 2.543.488
2021-01-20 2021-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 17.598 47.904 58,07
2021-01-15 2021-01-13 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -141 30.306 -0,46 59,50 -8.390 1.803.207
2021-01-06 2021-01-04 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
A - Award 51.107 51.107
2020-11-30 2020-11-25 4 IONS IONIS PHARMACEUTICALS INC
Non-Qualified Stock Option (right to buy)
M - Exercise -11.920 0 -100,00
2020-11-30 2020-11-25 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -11.920 30.447 -28,14 50,05 -596.596 1.523.872
2020-11-30 2020-11-25 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 11.920 42.367 39,15 39,87 475.250 1.689.172
2020-11-25 2020-11-24 4 IONS IONIS PHARMACEUTICALS INC
Non-Qualified Stock Option (right to buy)
M - Exercise -2.380 11.920 -16,64
2020-11-25 2020-11-24 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -2.380 30.447 -7,25 50,83 -120.975 1.547.621
2020-11-25 2020-11-24 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 2.380 32.827 7,82 39,87 94.891 1.308.812
2020-11-25 2020-11-23 4 IONS IONIS PHARMACEUTICALS INC
Non-Qualified Stock Option (right to buy)
M - Exercise -10.700 14.300 -42,80
2020-11-25 2020-11-23 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -10.700 30.447 -26,00 50,11 -536.177 1.525.699
2020-11-25 2020-11-23 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 10.700 41.147 35,14 39,87 426.609 1.640.531
2020-09-02 2020-08-31 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
J - Other 1 30.447 0,00 44,46 44 1.353.521
2020-03-03 2020-02-29 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
J - Other 378 30.446 1,26 43,16 16.316 1.314.141
2020-01-17 2020-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -13.139 27.639 -32,22
2020-01-17 2020-01-15 4 IONS IONIS PHARMACEUTICALS INC
Retricted Stock Units
A - Award 24.205 24.205
2020-01-17 2020-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
F - Taxes -4.654 30.068 -13,40 62,06 -288.827 1.866.020
2020-01-17 2020-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 13.139 34.722 60,88
2020-01-03 2020-01-02 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
A - Award 54.461 54.461
2019-12-05 2019-12-04 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -10.000 0 -100,00
2019-12-05 2019-12-04 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -10.000 21.583 -31,66 65,00 -650.000 1.402.895
2019-12-05 2019-12-04 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 10.000 31.583 46,33 14,69 146.900 463.954
2019-12-04 2019-12-02 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -5.000 10.000 -33,33
2019-12-04 2019-12-02 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -5.000 21.583 -18,81 65,06 -325.287 1.404.134
2019-12-04 2019-12-02 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 5.000 26.583 23,17 14,69 73.450 390.504
2019-07-02 2019-07-01 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
J - Other 141 21.583 0,66 45,70 6.444 986.440
2019-04-10 2019-04-08 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise 20.000 25.000 400,00
2019-04-10 2019-04-08 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise 2.240 15.000 17,55
2019-04-10 2019-04-08 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise 24.000 1.439 -106,38
2019-04-10 2019-04-08 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -20.000 21.442 -48,26 84,00 -1.680.000 1.801.128
2019-04-10 2019-04-08 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 20.000 41.442 93,27 39,87 797.400 1.652.293
2019-04-10 2019-04-08 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -2.240 21.442 -9,46 84,00 -188.160 1.801.128
2019-04-10 2019-04-08 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 2.240 23.682 10,45 14,69 32.906 347.889
2019-04-10 2019-04-08 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -24.000 21.442 -52,81 84,02 -2.016.593 1.801.658
2019-04-10 2019-04-08 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 24.000 45.442 111,93 47,34 1.136.160 2.151.224
2019-02-14 2019-02-13 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -999 21.442 -4,45 60,00 -59.940 1.286.520
2019-01-17 2019-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -8.085 15.048 -34,95
2019-01-17 2019-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 25.730 25.730
2019-01-17 2019-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
F - Taxes -2.908 22.034 -11,66 58,26 -169.420 1.283.701
2019-01-17 2019-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 8.085 24.942 47,96
2019-01-03 2019-01-02 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
A - Award 57.900 57.900
2019-01-03 2019-01-01 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
J - Other 407 17.264 2,41 36,45 14.834 629.238
2018-07-03 2018-07-01 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
J - Other 177 16.857 1,06 35,42 6.269 597.067
2018-01-17 2018-01-16 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale -2.723 16.680 -14,03 51,76 -140.942 863.357
2018-01-17 2018-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -6.732 10.217 -39,72
2018-01-17 2018-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 12.916 12.916
2018-01-17 2018-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 6.732 19.403 53,13
2018-01-02 2018-01-02 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
A - Award 58.125 58.125
2018-01-02 2018-01-01 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
J - Other 320 12.671 2,59 42,76 13.682 541.749
2017-10-17 2017-10-13 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -7.035 0 -100,00
2017-10-17 2017-10-13 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -426 0 -100,00
2017-10-17 2017-10-13 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -7.035 12.351 -36,29 60,00 -422.100 741.060
2017-10-17 2017-10-13 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 7.035 19.386 56,96 7,25 51.004 140.548
2017-10-17 2017-10-13 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -426 12.351 -3,33 60,00 -25.560 741.060
2017-10-17 2017-10-13 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 426 12.777 3,45 10,29 4.384 131.475
2017-10-17 2017-10-13 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -807 12.351 -6,13 60,00 -48.420 741.060
2017-07-03 2017-07-01 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
J - Other 196 13.158 1,51 40,66 7.968 534.945
2017-01-18 2017-01-17 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale -623 12.962 -4,59 46,29 -28.839 600.024
2017-01-18 2017-01-17 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale -539 11.991 -4,30 46,29 -24.950 555.063
2017-01-18 2017-01-17 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale -733 11.150 -6,17 46,29 -33.931 516.145
2017-01-18 2017-01-17 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale -546 10.008 -5,17 46,29 -25.275 463.280
2017-01-18 2017-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -1.594 4.779 -25,01
2017-01-18 2017-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -1.380 2.758 -33,35
2017-01-18 2017-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -1.875 1.875 -50,00
2017-01-18 2017-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -1.397 0 -100,00
2017-01-18 2017-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 7.537 7.537
2017-01-18 2017-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 1.594 13.585 13,29
2017-01-18 2017-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 1.380 12.530 12,38
2017-01-18 2017-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 1.875 11.883 18,74
2017-01-18 2017-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 1.397 10.554 15,26
2017-01-04 2017-01-03 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
A - Award 45.225 45.225
2017-01-04 2017-01-01 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
J - Other 640 9.157 7,51 20,76 13.284 190.072
2016-07-01 2016-07-01 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
J - Other 163 8.517 1,95 20,76 3.383 176.787
2016-01-19 2016-01-19 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale -550 8.354 -6,18 41,46 -22.802 346.334
2016-01-19 2016-01-19 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale -747 7.524 -9,03 41,46 -30.967 311.910
2016-01-19 2016-01-19 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale -556 6.396 -8,00 41,47 -23.056 265.225
2016-01-19 2016-01-19 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale -309 5.555 -5,27 41,46 -12.810 230.288
2016-01-19 2016-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -1.380 4.138 -25,01
2016-01-19 2016-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -1.875 3.750 -33,33
2016-01-19 2016-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -1.397 1.397 -50,00
2016-01-19 2016-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -775 0 -100,00
2016-01-19 2016-01-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 6.373 6.373
2016-01-19 2016-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 1.380 8.904 18,34
2016-01-19 2016-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 1.875 8.271 29,32
2016-01-19 2016-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 1.397 6.952 25,15
2016-01-19 2016-01-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 775 5.864 15,23
2016-01-04 2016-01-04 4 IONS IONIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
A - Award 38.240 38.240
2016-01-04 2016-01-01 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
J - Other 269 5.089 5,58 47,71 12.834 242.799
2015-07-02 2015-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
J - Other 265 4.820 5,82 48,59 12.875 234.185
2015-03-20 2015-03-19 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -8.000 17.240 -31,70
2015-03-20 2015-03-19 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -8.000 4.555 -63,72 75,00 -600.032 341.643
2015-03-20 2015-03-19 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 8.000 12.555 175,63 14,69 117.520 184.433
2015-03-09 2015-03-05 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -7.000 7.035 -49,88
2015-03-09 2015-03-05 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -8.000 426 -94,94
2015-03-09 2015-03-05 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -80 0 -100,00
2015-03-09 2015-03-05 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -7.000 4.555 -60,58 70,32 -492.226 320.298
2015-03-09 2015-03-05 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 7.000 11.555 153,68 7,25 50.750 83.774
2015-03-09 2015-03-05 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -8.000 4.555 -63,72 71,67 -573.344 326.448
2015-03-09 2015-03-05 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 8.000 12.555 175,63 10,29 82.320 129.191
2015-03-09 2015-03-05 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -80 4.555 -1,73 71,67 -5.733 326.448
2015-03-09 2015-03-05 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 80 4.635 1,76 11,27 902 52.236
2015-03-09 2015-03-05 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -3.015 4.555 -39,83 71,67 -216.079 326.448
2015-01-20 2015-01-16 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale -714 7.570 -8,62 67,96 -48.526 514.487
2015-01-20 2015-01-16 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale -533 6.409 -7,68 67,96 -36.225 435.581
2015-01-20 2015-01-16 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale -296 5.544 -5,07 67,96 -20.117 376.792
2015-01-20 2015-01-15 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -1.875 5.625 -25,00
2015-01-20 2015-01-15 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -1.398 2.794 -33,35
2015-01-20 2015-01-15 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -776 775 -50,03
2015-01-20 2015-01-15 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 5.518 5.518
2015-01-20 2015-01-15 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 1.875 8.284 29,26
2015-01-20 2015-01-15 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 1.398 6.942 25,22
2015-01-20 2015-01-15 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 776 5.840 15,32
2015-01-13 2015-01-12 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -597 5.064 -10,55 73,10 -43.641 370.178
2015-01-05 2015-01-02 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
A - Award 33.112 33.112
2015-01-05 2015-01-01 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
J - Other 273 5.661 5,07 30,05 8.203 170.099
2014-07-02 2014-07-02 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -164 5.388 -2,95 35,95 -5.896 193.699
2014-07-02 2014-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
J - Other 597 5.552 12,05 30,20 18.030 167.673
2014-01-24 2014-01-22 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -13.900 14.035 -49,76
2014-01-24 2014-01-22 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -8.300 25.240 -24,75
2014-01-24 2014-01-22 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -13.900 4.955 -73,72 50,05 -695.639 247.978
2014-01-24 2014-01-22 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 13.900 18.855 280,52 7,25 100.775 136.699
2014-01-24 2014-01-22 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -8.300 4.955 -62,62 50,05 -415.382 247.978
2014-01-24 2014-01-22 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 8.300 13.255 167,51 14,69 121.927 194.716
2014-01-17 2014-01-16 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale -533 4.955 -9,71 47,08 -25.094 233.288
2014-01-17 2014-01-16 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale -296 4.090 -6,75 47,08 -13.936 192.563
2014-01-17 2014-01-15 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -1.398 4.192 -25,01
2014-01-17 2014-01-15 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -776 1.551 -33,35
2014-01-17 2014-01-15 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 7.500 7.500
2014-01-17 2014-01-15 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 1.398 5.488 34,18
2014-01-17 2014-01-15 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 776 4.386 21,50
2014-01-08 2014-01-08 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -7.600 8.426 -47,42
2014-01-08 2014-01-08 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -7.600 3.610 -67,80 42,02 -319.352 151.692
2014-01-08 2014-01-08 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 7.600 11.210 210,53 10,29 78.204 115.351
2014-01-08 2014-01-06 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -7.400 80 -98,93
2014-01-08 2014-01-06 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -7.400 3.610 -67,21 38,83 -287.364 140.187
2014-01-08 2014-01-06 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 7.400 11.010 204,99 11,27 83.398 124.083
2014-01-03 2014-01-02 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
A - Award 45.000 45.000
2014-01-03 2014-01-01 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
J - Other 164 3.610 4,76 24,20 3.969 87.360
2013-07-12 2013-07-11 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -9.000 0 -100,00
2013-07-12 2013-07-11 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -9.000 3.446 -72,31 31,90 -287.100 109.927
2013-07-12 2013-07-11 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 9.000 12.446 261,17 11,12 100.080 138.400
2013-07-09 2013-07-09 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -10.358 16.026 -39,26
2013-07-09 2013-07-09 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -10.358 3.446 -75,04 30,04 -311.185 103.528
2013-07-09 2013-07-09 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 10.358 13.804 300,58 10,29 106.584 142.043
2013-07-09 2013-07-08 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -7.060 26.384 -21,11
2013-07-09 2013-07-08 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -22.940 7.480 -75,41
2013-07-09 2013-07-08 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -7.060 3.446 -67,20 30,09 -212.435 103.690
2013-07-09 2013-07-08 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 7.060 10.506 204,88 10,29 72.647 108.107
2013-07-09 2013-07-08 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -17.933 3.446 -83,88 30,09 -539.604 103.690
2013-07-09 2013-07-08 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 17.933 21.379 520,40 11,27 202.105 240.941
2013-07-09 2013-07-08 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -5.007 3.446 -59,23 30,03 -150.340 103.470
2013-07-09 2013-07-08 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 5.007 8.453 145,30 11,27 56.429 95.265
2013-07-09 2013-07-05 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -5.000 0 -100,00
2013-07-09 2013-07-05 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -2.220 30.420 -6,80
2013-07-09 2013-07-05 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -16.960 0 -100,00
2013-07-09 2013-07-05 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -5.000 3.446 -59,20 30,02 -150.075 103.432
2013-07-09 2013-07-05 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 5.000 8.446 145,10 19,08 95.400 161.150
2013-07-09 2013-07-05 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -2.220 3.446 -39,18 30,02 -66.633 103.432
2013-07-09 2013-07-05 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 2.220 5.666 64,42 11,27 25.019 63.856
2013-07-09 2013-07-05 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -16.960 3.446 -83,11 30,02 -509.054 103.432
2013-07-09 2013-07-05 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 16.960 20.406 492,16 14,47 245.411 295.275
2013-07-09 2013-07-05 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -1.625 3.446 -32,04 29,25 -47.531 100.796
2013-07-03 2013-07-03 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -5.000 5.000 -50,00
2013-07-03 2013-07-03 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -5.000 5.071 -49,65 29,02 -145.100 147.160
2013-07-03 2013-07-03 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 5.000 10.071 98,60 19,08 95.400 192.155
2013-07-03 2013-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
J - Other 817 5.071 19,21 9,20 7.514 46.638
2013-06-26 2013-06-25 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -12.000 16.960 -41,44
2013-06-26 2013-06-25 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -4.000 0 -100,00
2013-06-26 2013-06-25 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -1.049 0 -100,00
2013-06-26 2013-06-25 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -10.435 4.254 -71,04 27,86 -290.771 118.538
2013-06-26 2013-06-25 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 10.435 14.689 245,30 14,47 150.994 212.550
2013-06-26 2013-06-25 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -1.565 4.254 -26,89 28,32 -44.321 120.473
2013-06-26 2013-06-25 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1.565 5.819 36,79 14,47 22.646 84.201
2013-06-26 2013-06-25 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -4.000 4.254 -48,46 28,32 -113.280 120.473
2013-06-26 2013-06-25 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 4.000 8.254 94,03 15,38 61.520 126.947
2013-06-26 2013-06-25 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -1.049 4.254 -19,78 27,56 -28.910 117.240
2013-06-26 2013-06-25 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1.049 5.303 24,66 6,81 7.144 36.113
2013-06-26 2013-06-24 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -10.000 0 -100,00
2013-06-26 2013-06-24 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -20.000 4.000 -83,33
2013-06-26 2013-06-24 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -10.000 4.254 -70,16 25,16 -251.600 107.031
2013-06-26 2013-06-24 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 10.000 14.254 235,07 15,75 157.500 224.500
2013-06-26 2013-06-24 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -6.270 4.254 -59,58 25,16 -157.753 107.031
2013-06-26 2013-06-24 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 6.270 10.524 147,39 15,38 96.433 161.859
2013-06-26 2013-06-24 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -13.730 4.254 -76,35 25,22 -346.271 107.286
2013-06-26 2013-06-24 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 13.730 17.984 322,76 15,38 211.167 276.594
2013-04-23 2013-04-19 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -2.042 9.000 -18,49
2013-04-23 2013-04-19 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -2.042 4.254 -32,43 20,80 -42.474 88.483
2013-04-23 2013-04-19 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 2.042 6.296 48,00 11,12 22.707 70.012
2013-04-15 2013-04-11 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -7.000 11.042 -38,80
2013-04-15 2013-04-11 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -7.000 4.254 -62,20 19,52 -136.640 83.038
2013-04-15 2013-04-11 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 7.000 11.254 164,55 11,12 77.840 125.144
2013-03-22 2013-03-21 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -1.000 18.042 -5,25
2013-03-22 2013-03-21 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -1.000 4.254 -19,03 19,50 -19.500 82.953
2013-03-22 2013-03-21 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1.000 5.254 23,51 11,12 11.120 58.424
2013-02-01 2013-01-30 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
A - Award 33.540 33.540
2013-02-01 2013-01-30 4 ISIS ISIS PHARMACEUTICALS INC
Restricted StockUnits
A - Award 5.590 5.590
2013-01-17 2013-01-16 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale -345 4.254 -7,50 14,00 -4.830 59.556
2013-01-17 2013-01-15 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -776 2.327 -25,01
2013-01-17 2013-01-15 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 776 4.599 20,30
2013-01-03 2013-01-03 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -265 3.823 -6,48 10,84 -2.873 41.441
2013-01-03 2013-01-01 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
J - Other 898 4.088 28,15 8,87 7.969 36.277
2012-12-17 2012-12-13 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -6.000 0 -100,00
2012-12-17 2012-12-13 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -6.000 3.190 -65,29 9,63 -57.751 30.704
2012-12-17 2012-12-13 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 6.000 9.190 188,09 5,25 31.500 48.248
2012-07-11 2012-07-09 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
M - Exercise -5.686 6.000 -48,66
2012-07-11 2012-07-09 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -1.000 3.190 -23,87 13,45 -13.450 42.906
2012-07-11 2012-07-09 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 1.000 4.190 31,35 5,25 5.250 21.998
2012-07-11 2012-07-09 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -2.000 3.190 -38,54 13,49 -26.980 43.033
2012-07-11 2012-07-09 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 2.000 5.190 62,70 5,25 10.500 27.248
2012-07-11 2012-07-09 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -2.686 3.190 -45,71 13,47 -36.180 42.969
2012-07-11 2012-07-09 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise X 2.686 5.876 84,20 5,25 14.102 30.849
2012-07-03 2012-07-03 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -2.434 3.190 -43,28 12,91 -31.423 41.183
2012-07-03 2012-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
J - Other 1.300 5.624 30,06 6,13 7.967 34.467
2012-06-14 2012-06-14 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale X -1.579 4.324 -26,75 10,86 -17.148 46.959
2012-01-17 2012-01-15 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 3.103 3.103
2012-01-03 2012-01-03 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
A - Award 27.935 27.935
2012-01-03 2012-01-01 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
J - Other 1.625 5.903 37,99 6,13 9.959 36.177
2010-01-05 2010-01-04 4 ISIS ISIS PHARMACEUTICALS INC
Employee Stock Option (right to buy)
A - Award 32.640 32.640
2010-01-05 2010-01-01 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
J - Other 1.579 1.579 9,44 14.911 14.911
2008-08-19 3 ISIS ISIS PHARMACEUTICALS INC
No securities are beneficially owned
0
P
Acquisto sul mercato aperto o privato di un titolo non derivato o derivato
S
Vendita sul mercato aperto o privato di un titolo non derivato o derivato
A
Concessione, assegnazione o altra acquisizione di titoli dall'azienda (ad esempio un'opzione)
C
Conversione di un derivato
D
Vendita o trasferimento di titoli alla società
F
Pagamento del prezzo di esercizio o del debito fiscale con la quota di titoli ricevuta dalla società
G
Regalo di titoli da parte o a favore dell'insider
K
Equity swap e operazioni di copertura analoghe
M
Esercizio o conversione di un titolo derivato ricevuto dall'azienda (ad esempio un'opzione)
V
Una transazione dichiarata volontariamente sul modulo 4
J
Altro (accompagnato da una nota a piè di pagina che descriva l'operazione)