Cytosorbents Corporation
US ˙ NasdaqCM ˙ US23283X2062

SecurityCTSO / Cytosorbents Corporation
InstitutionRenaissance Technologies Llc
ManagerJames Simons
Latest Disclosed Ownership100,720 shares
Latest Disclosed Value $ 57,038
Renaissance Technologies Llc reports 0.60% increase in ownership of CTSO / Cytosorbents Corporation

On May 14, 2026 - Renaissance Technologies Llc filed a 13F-HR form disclosing ownership of 100,720 shares of Cytosorbents Corporation (US:CTSO) valued at $57,038 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 12, 2026 disclosing 100,120 shares of Cytosorbents Corporation. This represents a change in shares of 0.60% during the quarter. The current value of the position is $46,230 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-14 2026-03-31 13F CYTOSORBENTS COM NEW 23283X206 100,720 600 0.60 57 -9.52 0.0001
2026-02-12 2025-12-31 13F CYTOSORBENTS COM NEW 23283X206 100,120 -34,685 -25.73 64 -49.60 0.0001
2025-11-13 2025-09-30 13F CYTOSORBENTS COM NEW 23283X206 134,805 18,166 15.57 126 -16.11 0.0002
2025-08-13 2025-06-30 13F CYTOSORBENTS COM NEW 23283X206 116,639 -108,615 -48.22 149 -33.78 0.0002
2025-05-14 2025-03-31 13F CYTOSORBENTS COM NEW 23283X206 225,254 137,234 155.91 225 181.25 0.0003
2025-02-13 2024-12-31 13F CYTOSORBENTS COM NEW 23283X206 88,020 8,400 10.55 80 -32.77 0.0001
2024-11-13 2024-09-30 13F CYTOSORBENTS COM NEW 23283X206 79,620 3,800 5.01 119 124.53 0.0002
2024-08-09 2024-06-30 13F CYTOSORBENTS COM NEW 23283X206 75,820 -3,800 -4.77 53 0.0001
2024-05-13 2024-03-31 13F CYTOSORBENTS COM NEW 23283X206 79,620 -95,700 -54.59 0 0.0001
2024-02-13 2023-12-31 13F CYTOSORBENTS COM NEW 23283X206 175,320 56,220 47.20 0 0.0003
2023-11-14 2023-09-30 13F CYTOSORBENTS COM NEW 23283X206 119,100 200 0.17 0 0.0004
2023-08-11 2023-06-30 13F CYTOSORBENTS COM NEW 23283X206 118,900 300 0.25 0 0.0006
2023-05-12 2023-03-31 13F CYTOSORBENTS COM NEW 23283X206 118,600 200 0.17 0 0.0005
2023-02-13 2022-12-31 13F CYTOSORBENTS COM NEW 23283X206 118,400 -79,396 -40.14 0 -100.00 0.0003
2022-11-14 2022-09-30 13F CYTOSORBENTS COM NEW 23283X206 197,796 57,676 41.16 269 -12.38 0.0004
2022-08-12 2022-06-30 13F CYTOSORBENTS COM NEW 23283X206 140,120 55,220 65.04 307 13.28 0.0004
2022-05-13 2022-03-31 13F CYTOSORBENTS COM NEW 23283X206 84,900 84,900 271 0.0003
2021-11-12 2021-09-30 13F CYTOSORBENTS COM NEW 23283X206 0 -140,100 -100.00 0 -100.00
2021-08-13 2021-06-30 13F CYTOSORBENTS COM NEW 23283X206 140,100 -39,900 -22.17 1,058 -32.27 0.0013
2021-05-13 2021-03-31 13F CYTOSORBENTS COM NEW 23283X206 180,000 106,900 146.24 1,562 167.92 0.0019
2021-02-10 2020-12-31 13F CYTOSORBENTS COM NEW 23283X206 73,100 -22,900 -23.85 583 -23.89 0.0006
2020-11-13 2020-09-30 13F CYTOSORBENTS COM NEW 23283X206 96,000 96,000 766 0.0008
2019-08-12 2019-06-30 13F CYTOSORBENTS COM NEW 23283X206 0 -38,800 -100.00 0 -100.00
2019-05-14 2019-03-31 13F CYTOSORBENTS COM NEW 23283X206 38,800 -82,900 -68.12 294 -70.09 0.0003
2019-02-12 2018-12-31 13F CYTOSORBENTS COM NEW 23283X206 121,700 -108,600 -47.16 983 -62.55 0.0011
2018-08-13 2018-06-30 13F/A-1 CYTOSORBENTS COM NEW 23283X206 230,300 230,300 2,625 0.0029
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.