BeOne Medicines AG - Depositary Receipt (Common Stock)
DE ˙ DB ˙ US07725L1026
236,00 € ↑2,00 (0,85%)
2026-06-04
PREZZO DELLE AZIONI
SecurityDE:49BA / BeOne Medicines AG - Depositary Receipt (Common Stock)
InstitutionBarclays Plc
Latest Disclosed Ownership24,801 shares
Latest Disclosed Value $ 7,534,791
Barclays Plc ownership in 49BA / BeOne Medicines AG - Depositary Receipt (Common Stock)

On February 13, 2026 - Barclays Plc filed a 13F-HR form disclosing ownership of 24,801 shares of BeOne Medicines AG - Depositary Receipt (Common Stock) (DE:49BA) valued at $6,398,658 USD as of December 31, 2025. The entity filed a previous 13F-HR/A on March 31, 2026 disclosing 13,408 shares of BeOne Medicines AG - Depositary Receipt (Common Stock). This represents a change in shares of 84.97% during the quarter. The current value of the position is $5,853,036 USD.

Barclays Plc has a history of taking positions in derivatives of the underlying security (49BA) in the form of stock options. The firm currently holds call options representing 10,500 of underlying shares valued at $3,190,005 USD and put options representing 10,500 of underlying shares valued at $3,190,005 USD .

Note: prior versions of this page mistakenly stated that the share values represented the number of options, not the number of underlying shares. For more information on the data backing these reports, please see the SEC document Frequently Asked Questions About Form 13F.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Institutional Put/Call Ratios
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In addition to reporting standard equity and debt issues, institutions with more than 100MM assets under management must also disclose their put and call option holdings. Since put options generally indicate negative sentiment, and call options indicate positive sentiment, we can get a sense of the overall institutional sentiment by plotting the ratio of puts to calls. The chart to the right plots the historical put/call ratio for this instrument.

Using Put/Call Ratio as an indicator of investor sentiment overcomes one of the key deficiencies of using total institutional ownership, which is that a significant amount of assets under management are invested passively to track indices. Passively-managed funds do not typically buy options, so the put/call ratio indicator more closely tracks the sentiment of actively-managed funds.

DE:49BA / BeOne Medicines AG - Depositary Receipt (Common Stock) Historical Put/Call Ratio
Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-02-13 2025-12-31 13F BEONE MEDICINES ADR 07725L102 24,801 11,393 84.97 7,535 64.93 0.0018
2026-03-31 2025-09-30 13F/A-3 BEONE MEDICINES ADR 07725L102 13,408 -11,495 -46.16 4,568 -24.22 0.0010
2026-03-19 2025-09-30 13F/A-2 BEIGENE ADR 07725L102 10,829 -14,074 2,431 0.0006
2025-11-12 2025-09-30 13F BEONE MEDICINES ADR 07725L102 13,408 -11,495 4,568 0.0010
2026-02-27 2025-06-30 13F/A-2 BEONE MEDICINES ADR 07725L102 24,903 -17,843 -41.74 6,028 -48.19 0.0014
2025-08-14 2025-06-30 13F/A-1 BEONE MEDICINES ADR 07725L102 24,903 -17,843 6 0.0014
2025-08-13 2025-06-30 13F BEONE MEDICINES ADR 07725L102 24,903 -17,843 6 0.0005
2026-03-17 2025-03-31 13F/A-1 BEIGENE ADR 07725L102 42,746 36,717 609.01 11,634 945.28 0.0033
2025-05-15 2025-03-31 13F BEIGENE ADR 07725L102 42,746 36,717 12 0.0033
2026-03-19 2024-12-31 13F/A-1 BEIGENE ADR 07725L102 6,029 -4,800 -44.33 1,114 -54.22 0.0003
2025-02-13 2024-12-31 13F BEIGENE ADR 07725L102 6,029 -4,800 1 0.0003
2026-03-31 2024-09-30 13F/A-2 BEIGENE ADR 07725L102 10,829 240 2.27 2,431 60.99 0.0006
2024-11-19 2024-09-30 13F/A-1 BEIGENE ADR 07725L102 10,829 240 2 0.0006
2024-11-15 2024-09-30 13F BEIGENE ADR 07725L102 10,829 240 2 0.0002
2026-03-23 2024-06-30 13F/A-1 BEIGENE ADR 07725L102 10,589 411 4.04 1,511 -5.09 0.0005
2024-08-14 2024-06-30 13F BEIGENE ADR 07725L102 10,589 411 2 0.0005
2026-03-24 2024-03-31 13F/A-1 BEIGENE ADR 07725L102 10,178 9,610 1,691.90 1,592 1,459.80 0.0006
2024-05-15 2024-03-31 13F BEIGENE ADR 07725L102 10,178 9,610 2 0.0006
2026-03-25 2023-12-31 13F/A-1 BEIGENE ADR 07725L102 568 -250 -30.56 102 -30.61 0.0000
2024-02-15 2023-12-31 13F BEIGENE ADR 07725L102 568 -250 0 0.0000
2026-03-26 2023-09-30 13F/A-1 BEIGENE ADR 07725L102 818 -213 -20.66 147 -19.67 0.0001
2023-11-07 2023-09-30 13F BEIGENE ADR 07725L102 818 -213 0 0.0001
2026-03-30 2023-06-30 13F/A-2 BEIGENE ADR 07725L102 1,031 942 1,058.43 184 863.16 0.0001
2023-09-20 2023-06-30 13F/A-1 BEIGENE ADR 07725L102 1,031 942 0 0.0001
2023-08-03 2023-06-30 13F BEIGENE ADR 07725L102 1,031 942 0 0.0001
2026-03-30 2023-03-31 13F/A-1 BEIGENE ADR 07725L102 89 -2,911 -97.03 19 -97.12 0.0000
2023-05-04 2023-03-31 13F BEIGENE ADR 07725L102 89 -2,911 0 0.0000
2026-03-30 2022-12-31 13F/A-1 BEIGENE ADR 07725L102 3,000 -37,690 -92.63 660 -87.99 0.0003
2023-02-13 2022-12-31 13F BEIGENE ADR 07725L102 3,000 -37,690 1 0.0003
2022-11-03 2022-09-30 13F BEIGENE ADR 07725L102 40,690 -27,090 -39.97 5,486 -49.99 0.0060
2022-08-12 2022-06-30 13F BEIGENE ADR 07725L102 67,780 -4,162 -5.79 10,970 -19.15 0.0067
2022-05-16 2022-03-31 13F BEIGENE ADR 07725L102 71,942 31,864 79.50 13,568 24.96 0.0106
2022-02-23 2021-12-31 13F/A-1 BEIGENE ADR 07725L102 40,078 1,994 5.24 10,858 -21.46 0.0040
2022-02-14 2021-12-31 13F BEIGENE ADR 07725L102 40,078 1,994 10,858 0.0040
2021-11-09 2021-09-30 13F BEIGENE ADR 07725L102 38,084 5,104 15.48 13,824 22.14 0.0062
2021-08-13 2021-06-30 13F BEIGENE ADR 07725L102 32,980 5,287 19.09 11,318 17.42 0.0053
2021-05-13 2021-03-31 13F BEIGENE ADR 07725L102 27,693 -48,424 -63.62 9,639 -50.99 0.0052
2021-02-11 2020-12-31 13F BEIGENE ADR 07725L102 76,117 10,326 15.70 19,668 4.36 0.0104
2020-11-12 2020-09-30 13F BEIGENE ADR 07725L102 65,791 -1,227 -1.83 18,846 49.26 0.0112
2020-08-12 2020-06-30 13F BEIGENE ADR 07725L102 67,018 -25,532 -27.59 12,626 10.81 0.0098
2020-05-13 2020-03-31 13F BEIGENE ADR 07725L102 92,550 18,198 24.48 11,394 -7.55 0.0090
2020-02-10 2019-12-31 13F BEIGENE ADR 07725L102 74,352 10,134 15.78 12,324 56.71 0.0068
2019-11-15 2019-09-30 13F/A-1 BEIGENE ADR 07725L102 64,218 -2,468 -3.70 7,864 -4.85 0.0049
2019-11-14 2019-09-30 13F BEIGENE ADR 07725L102 64,218 -2,468 7,864 1,818.1657
2019-08-14 2019-06-30 13F BEIGENE ADR 07725L102 66,686 64,652 3,178.56 8,265 2,972.49 0.0051
2019-05-15 2019-03-31 13F BEIGENE ADR 07725L102 2,034 -8,194 -80.11 269 -81.25 0.0002
2019-02-14 2018-12-31 13F BEIGENE ADR 07725L102 10,228 4,731 86.07 1,435 51.53 0.0011
2018-11-14 2018-09-30 13F BEIGENE ADR 07725L102 5,497 5,491 91,516.67 947 94,600.00 0.0007
2018-08-14 2018-06-30 13F BEIGENE ADR 07725L102 6 -11,740 -99.95 1 -99.95 0.0000
2018-05-15 2018-03-31 13F BEIGENE ADR 07725L102 11,746 11,669 15,154.55 1,974 24,575.00 0.0015
2018-02-14 2017-12-31 13F BEIGENE ADR 07725L102 77 -4,667 -98.38 8 -98.37 0.0000
2017-11-14 2017-09-30 13F BEIGENE ADR 07725L102 4,744 4,582 2,828.40 491 6,914.29 0.0005
2017-08-14 2017-06-30 13F BEIGENE ADR 07725L102 162 144 800.00 7 600.00 0.0000
2017-05-15 2017-03-31 13F BEIGENE ADR 07725L102 18 -418 -95.87 1 -92.31 0.0000
2017-02-14 2016-12-31 13F BEIGENE ADR 07725L102 436 436 13 0.0000
Disclosed Call Options
File
Date
Effective
Date
Form Security Class ID Opt Avg Share
Price
Shares ΔShares
(%)
Value
(x1000)
ΔValue
(%)
Prior Allocation
(%)
Allocation
(%)
ΔAllocation
(%)
Cost Basis
(x1000)
Profit
(x1000)
Return
(%)
2026-02-13 2025-12-31 13F BEONE MEDICINES OPT Call 10,500 -22.22 3,190 -30.64 n/a n/a n/a
2026-03-31 2025-09-30 13F/A BEONE MEDICINES OPT Call 13,500 4,599 n/a n/a n/a
2026-03-19 2025-09-30 13F/A BEIGENE OPT Call 57,000 12,797 n/a n/a n/a
2025-11-12 2025-09-30 13F BEONE MEDICINES OPT Call 13,500 4,599 n/a n/a n/a
2026-03-19 2024-12-31 13F/A BEIGENE OPT Call 0 -100.00 0 -100.00 n/a n/a n/a
2025-02-13 2024-12-31 13F BEIGENE OPT Call 0 0 n/a n/a n/a
2024-11-19 2024-09-30 13F/A BEIGENE OPT Call 57,000 13 n/a n/a n/a
2026-03-31 2024-09-30 13F/A BEIGENE OPT Call 57,000 90.00 12,797 199.00 n/a n/a n/a
2024-11-15 2024-09-30 13F BEIGENE OPT Call 57,000 13 n/a n/a n/a
2026-03-23 2024-06-30 13F/A BEIGENE OPT Call 30,000 4,280 n/a n/a n/a
2024-08-14 2024-06-30 13F BEIGENE OPT Call 30,000 4 n/a n/a n/a
2026-03-24 2024-03-31 13F/A BEIGENE OPT Call 0 -100.00 0 -100.00 n/a n/a n/a
2024-05-15 2024-03-31 13F BEIGENE OPT Call 0 0 n/a n/a n/a
2026-03-25 2023-12-31 13F/A BEIGENE OPT Call 15,000 2,705 n/a n/a n/a
2024-02-15 2023-12-31 13F BEIGENE OPT Call 15,000 3 n/a n/a n/a
2019-02-14 2018-12-31 13F BEIGENE OPT Call 0 -100.00 0 -100.00 n/a n/a n/a
2018-11-14 2018-09-30 13F BEIGENE OPT Call 8,600 1,481 n/a n/a n/a
Disclosed Put Options
File
Date
Effective
Date
Form Security Class ID Opt Avg Share Price Shares ΔShares
(%)
Value
(x1000)
ΔValue
(%)
Prior Allocation
(%)
Allocation
(%)
ΔAllocation
(%)
Cost Basis
(x1000)
Profit
(x1000)
Return
(%)
2026-02-13 2025-12-31 13F BEONE MEDICINES OPT Put 10,500 -22.22 3,190 -30.64 n/a n/a n/a
2026-03-19 2025-09-30 13F/A BEIGENE OPT Put 57,000 12,797 n/a n/a n/a
2026-03-31 2025-09-30 13F/A BEONE MEDICINES OPT Put 13,500 4,599 n/a n/a n/a
2025-11-12 2025-09-30 13F BEONE MEDICINES OPT Put 13,500 4,599 n/a n/a n/a
2026-03-19 2024-12-31 13F/A BEIGENE OPT Put 0 -100.00 0 -100.00 n/a n/a n/a
2025-02-13 2024-12-31 13F BEIGENE OPT Put 0 0 n/a n/a n/a
2024-11-19 2024-09-30 13F/A BEIGENE OPT Put 57,000 13 n/a n/a n/a
2026-03-31 2024-09-30 13F/A BEIGENE OPT Put 57,000 12,797 n/a n/a n/a
2024-11-15 2024-09-30 13F BEIGENE OPT Put 57,000 13 n/a n/a n/a
2026-03-24 2024-03-31 13F/A BEIGENE OPT Put 0 -100.00 0 -100.00 n/a n/a n/a
2024-05-15 2024-03-31 13F BEIGENE OPT Put 0 0 n/a n/a n/a
2026-03-25 2023-12-31 13F/A BEIGENE OPT Put 15,000 2,705 n/a n/a n/a
2024-02-15 2023-12-31 13F BEIGENE OPT Put 15,000 3 n/a n/a n/a
2019-02-14 2018-12-31 13F BEIGENE OPT Put 0 -100.00 0 -100.00 n/a n/a n/a
2018-11-14 2018-09-30 13F BEIGENE OPT Put 30,000 5,167 n/a n/a n/a
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.