CGTX / Cognition Therapeutics, Inc. - Depositi SEC, Relazione annuale, dichiarazione di delega

Cognition Therapeutics, Inc.
US ˙ NasdaqCM ˙ US19243B1026

Statistiche di base
CIK 1455365
SEC Filings
All companies that sell securities in the United States must register with the Securities and Exchange Commission (SEC) and file reports on a regular basis. These reports include company annual reports (10K, 10Q), news updates (8K), investor presentations (found in 8Ks), insider trades (form 4), ownership reports (13D, and 13G), and reports related to the specific securities sold, such as registration statements and prospectus. This page shows recent SEC filings related to Cognition Therapeutics, Inc.
SEC Filings (Chronological Order)
Questa pagina fornisce un elenco completo e cronologico dei depositi SEC, esclusi i documenti di proprietà che forniamo altrove.
August 28, 2025 EX-1.1

PLACEMENT AGENCY AGREEMENT

Exhibit 1.1 Execution Version PLACEMENT AGENCY AGREEMENT August 27, 2025 Titan Partners Group LLC, a division of American Capital Partners, LLC 4 World Trade Center, 29th Floor New York, NY 10007 Ladies and Gentlemen: Introductory. This Placement Agency Agreement (this “Agreement”) sets forth the terms upon which Titan Partners Group LLC, a division of American Capital Partners, LLC (“Titan Partne

August 28, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 27, 2025 Cognition Therape

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 27, 2025 Cognition Therapeutics, Inc. (Exact name of registrant as specified in its charter) Delaware 001-40886 13-4365359 (State or other jurisdiction of incorporation) (Commi

August 28, 2025 EX-10.1

SECURITIES PURCHASE AGREEMENT

Exhibit 10.1 SECURITIES PURCHASE AGREEMENT This Securities Purchase Agreement (this “Agreement”) is dated as of August 27, 2025, between Cognition Therapeutics, Inc., a company incorporated under the laws of Delaware (the “Company”), and each purchaser identified on the signature pages hereto (each, including its successors and assigns, a “Purchaser” and collectively the “Purchasers”). WHEREAS, su

August 28, 2025 EX-4.1

AGENT’S PURCHASE WARRANT COGNITION THERAPEUTICS, INC.

Exhibit 4.1 AGENT’S PURCHASE WARRANT COGNITION THERAPEUTICS, INC. Warrant Shares: 1 Initial Exercise Date: [], 2026 2 Issue Date: [], 2025 This AGENT’S PURCHASE WARRANT (the “Warrant”) certifies that, for value received, American Capital Partners, LLC or its assigns (the “Holder”) is entitled, upon the terms and subject to the limitations on exercise and the conditions hereinafter set forth, at an

August 28, 2025 EX-FILING FEES

Security Type

Calculation of Filing Fee Tables S-3 COGNITION THERAPEUTICS INC Table 1: Newly Registered and Carry Forward Securities ☑Not Applicable Security Type Security Class Title Fee Calculation or Carry Forward Rule Amount Registered Proposed Maximum Offering Price Per Unit Maximum Aggregate Offering Price Fee Rate Amount of Registration Fee Carry Forward Form Type Carry Forward File Number Carry Forward

August 28, 2025 424B5

14,700,000 Shares of Common Stock

TABLE OF CONTENTS  Filed Pursuant to Rule 424(b)(5)  Registration Statement No. 333-268992 PROSPECTUS SUPPLEMENT (To Prospectus dated January 3, 2023) 14,700,000 Shares of Common Stock We are offering 14,700,000 shares of common stock in a registered direct offering to a limited number of purchasers pursuant to this prospectus supplement and the accompanying prospectus. We are also registering the

August 26, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 26, 2025 Cognition Therapeut

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 26, 2025 Cognition Therapeutics, Inc.

August 7, 2025 EX-99.1

Cognition Therapeutics Reports Financial Results for the Second Quarter 2025 and Highlights Progress Across Clinical Programs - Discussed plans to support a pivotal Alzheimer’s disease program with FDA at end-of-phase 2 meeting - - Initiated expanded

Exhibit 99.1 Cognition Therapeutics Reports Financial Results for the Second Quarter 2025 and Highlights Progress Across Clinical Programs - Discussed plans to support a pivotal Alzheimer’s disease program with FDA at end-of-phase 2 meeting - - Initiated expanded access program (EAP) for people with dementia with Lewy bodies (DLB) - - Surpassed 50% enrollment in Phase 2 ‘START’ study of zervimesin

August 7, 2025 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2025 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 00

August 7, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 7, 2025 Cognition Therapeuti

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 7, 2025 Cognition Therapeutics, Inc.

June 20, 2025 8-K

Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 18, 2025 Cognition Therapeutics, Inc.

June 3, 2025 8-K

Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 3, 2025 Cognition Therapeutics, Inc.

June 3, 2025 EX-99.1

Philanthropic Donor Funds Cognition Therapeutics’ Expanded Access Program for Zervimesine (CT1812) in Dementia with Lewy Bodies Dr. James Galvin of the University of Miami to Serve as Lead Investigator First Site Initiated: Banner Sun Health Research

Exhibit 99.1 Philanthropic Donor Funds Cognition Therapeutics’ Expanded Access Program for Zervimesine (CT1812) in Dementia with Lewy Bodies Dr. James Galvin of the University of Miami to Serve as Lead Investigator First Site Initiated: Banner Sun Health Research Institute Purchase, NY – June 3, 2025 – Cognition Therapeutics, Inc., (the “Company” or “Cognition”) (NASDAQ: CGTX), a clinical-stage co

June 2, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 2, 2025 Cognition Therapeutics

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 2, 2025 Cognition Therapeutics, Inc.

June 2, 2025 EX-99.1

Targeting Pathogenic Oligomers: June 2025 A Disruptive Approach to the Treatment of Neurodegenerative Diseases 2 FORWARD-LOOKING STATEMENTS This presentation contains forward-looking statements within the meaning of The Private Securities Litigation

Exhibit 99.1 Targeting Pathogenic Oligomers: June 2025 A Disruptive Approach to the Treatment of Neurodegenerative Diseases 2 FORWARD-LOOKING STATEMENTS This presentation contains forward-looking statements within the meaning of The Private Securities Litigation Reform Act of 1995. All statements contained in this presentation, other than statements of historical facts or statements that relate to

May 8, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 8, 2025 Cognition Therapeutics,

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 8, 2025 Cognition Therapeutics, Inc.

May 8, 2025 EX-99.1

Cognition Therapeutics Reports Topline Results Showing Oral Zervimesine (CT1812) Reduced Lesion Growth in Phase 2 Study in Geographic Atrophy Zervimesine treatment slowed the rate of GA lesion growth by 28.6% compared to placebo Observed GA lesion ar

Exhibit 99.1 Cognition Therapeutics Reports Topline Results Showing Oral Zervimesine (CT1812) Reduced Lesion Growth in Phase 2 Study in Geographic Atrophy Zervimesine treatment slowed the rate of GA lesion growth by 28.6% compared to placebo Observed GA lesion area was reduced by 28.2% at 18 months compared to placebo Dry AMD results validate zervimesine’s potential across degenerative disease ind

May 7, 2025 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2025 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 0

May 7, 2025 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 7, 2025 Cognition Therapeutics, Inc.

May 7, 2025 EX-99.1

Cognition Therapeutics Reports Financial Results for the First Quarter 2025 and Provides Business Update - End-of-Phase 2 meeting with FDA requested for Alzheimer’s disease – - Phase 2 results in dementia with Lewy bodies accepted for oral presentati

Exhibit 99.1 Cognition Therapeutics Reports Financial Results for the First Quarter 2025 and Provides Business Update - End-of-Phase 2 meeting with FDA requested for Alzheimer’s disease – - Phase 2 results in dementia with Lewy bodies accepted for oral presentation at AAIC – - Two posters at ARVO describe zervimesine's role supporting retinal cell health - Purchase, NY – May 7, 2025 – Cognition Th

April 28, 2025 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

TABLE OF CONTENTS UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 ☒ Filed by the Registrant ☐ Filed by a Party other than the Registrant Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☒ Defi

April 28, 2025 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 x Filed by the Registrant ¨ Filed by a Party other than the Registrant Check the appropriate box: ¨ Preliminary Proxy Statement ¨ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ¨ Definitive Proxy State

March 20, 2025 EX-99.1

Cognition Therapeutics Reports Year End 2024 Financial Results and Provides Business Update Positive Results with Zervimesine (CT1812) in Phase 2 SHIMMER Dementia with Lewy Bodies (DLB) Phase 2 SHINE Data Show Dramatic Slowing of Cognitive Decline wi

Exhibit 99.1 Cognition Therapeutics Reports Year End 2024 Financial Results and Provides Business Update Positive Results with Zervimesine (CT1812) in Phase 2 SHIMMER Dementia with Lewy Bodies (DLB) Phase 2 SHINE Data Show Dramatic Slowing of Cognitive Decline with Zervimesine in a Key Pre-specified Alzheimer’s Disease Subgroup 2025 Objective: Advance Zervimesine into Late-stage Trials for DLB and

March 20, 2025 EX-19.1

Cognition Therapeutics, Inc.’s Insider Trading Policy

Exhibit 19.1 COGNITION THERAPEUTICS, INC. INSIDER TRADING POLICY Effective October 7, 2021 I.Purpose Cognition Therapeutics, Inc. (the “Company”) has adopted this Insider Trading Policy (this “Policy”) to satisfy the Company’s obligation to prevent insider trading and to help the Company’s personnel and its external advisors avoid violating insider trading laws. II.Persons Subject to the Policy Th

March 20, 2025 424B5

Up to $14,583,831 Common Stock

Filed Pursuant to Rule 424(b)(5) Registration No. 333-268992 PROSPECTUS SUPPLEMENT (To Prospectus dated January 3, 2023, as supplemented by Prospectus Supplement dated March 27, 2023, as supplement by Prospectus Supplement dated June 28, 2023) Up to $14,583,831 Common Stock This prospectus supplement amends and supplements the information in the prospectus, dated January 3, 2023, filed with the Se

March 20, 2025 EX-FILING FEES

Filing Fee Table.

Exhibit 107 Calculation of Filing Fee Tables Form S-8 (Form Type) Cognition Therapeutics, Inc.

March 20, 2025 EX-3.3

Amendment to the Second Amended and Restated Bylaws of Cognition Therapeutics, Inc.

Exhibit 3.3 AMENDMENT TO THE SECOND AMENDED AND RESTATED BYLAWS OF COGNITION THERAPEUTICS, INC.         The Second Amended and Restated Bylaws (the “Bylaws”) of Cognition Therapeutics, Inc., a Delaware corporation (the “Corporation”), are hereby amended as follows, effective as of March 19, 2025. 1. Section 1.5 of ARTICLE II of the Bylaws is hereby amended and restated in its entirety to read as f

March 20, 2025 EX-10.3

Office Lease Agreement between RJ Equities LP and Cognition Therapeutics, Inc., dated July 1, 2017, as amended

Exhibit 10.3 LAB LEASE AGREEMENT between RJ EQUITIES LP (Landlord) and COGNITITION THERAPEUTICS, INC. (Tenant) Dated: January 20th, 2015 TABLE OF CONTENTS ARTICLEI. BASIC TERMS 1 ARTICLE 2. PREMISES 2 ARTICLE 3. TERM AND COMMENCEMENT 2 ARTICLE 4. CONSTRUCTION OF PREMISES 4 ARTICLE 5. BASE RENT 4 ARTICLE 6. RENT ESCALATION 5 ARTICLE 7. LATE PAYMENT 9 ARTICLE 8. USE OF PREMISES 9 ARTICLE 9. COMMON A

March 20, 2025 S-8

As filed with the Securities and Exchange Commission on March 20, 2025

As filed with the Securities and Exchange Commission on March 20, 2025 Registration No.

March 20, 2025 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2024 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For The Transition Period From To Commission file number: 001-40886 COGNITI

March 20, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 20, 2025 Cognition Therapeuti

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 20, 2025 Cognition Therapeutics, Inc.

March 20, 2025 EX-21.1

Subsidiaries of Cognition Therapeutics, Inc.

Exhibit 21.1 List of Subsidiaries None.

March 12, 2025 8-K

Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 12, 2025 Cognition Therapeutics, Inc.

February 26, 2025 EX-99.1

Cognition Therapeutics’ Successfully Passes Pre-defined Futility Analysis of Phase 2 Study of Oral Zervimesine (CT1812) in Geographic Atrophy Masked Analysis Shows Participants Receiving Oral Zervimesine for at Least 6 Months Experienced Slower Lesio

Exhibit 99.1 Cognition Therapeutics’ Successfully Passes Pre-defined Futility Analysis of Phase 2 Study of Oral Zervimesine (CT1812) in Geographic Atrophy Masked Analysis Shows Participants Receiving Oral Zervimesine for at Least 6 Months Experienced Slower Lesion Growth than Participants Receiving Placebo Following the Futility Analysis, Management Concluded the Phase 2 Study, Preserving Capital

February 26, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 26, 2025 Cognition Therape

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 26, 2025 Cognition Therapeutics, Inc.

January 28, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 28, 2025 Cognition Therapeu

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 28, 2025 Cognition Therapeutics, Inc.

January 28, 2025 EX-99.1

2 FORWARD-LOOKING STATEMENTS This presentation contains forward-looking statements within the meaning of The Private Securities Litigation Reform Act of 1995. All statements contained in this presentation, other than statements of historical facts or

Exhibit 99.1 Targeting Pathogenic Oligomers: January 2025 A Disruptive Approach to the Treatment of Neurodegenerative Diseases 2 FORWARD-LOOKING STATEMENTS This presentation contains forward-looking statements within the meaning of The Private Securities Litigation Reform Act of 1995. All statements contained in this presentation, other than statements of historical facts or statements that relate

January 13, 2025 EX-99.1

2 FORWARD-LOOKING STATEMENTS This presentation contains forward-looking statements within the meaning of The Private Securities Litigation Reform Act of 1995. All statements contained in this presentation, other than statements of historical facts or

Exhibit 99.1 Targeting Pathogenic Oligomers: January 2025 A Disruptive Approach to the Treatment of Neurodegenerative Diseases 2 FORWARD-LOOKING STATEMENTS This presentation contains forward-looking statements within the meaning of The Private Securities Litigation Reform Act of 1995. All statements contained in this presentation, other than statements of historical facts or statements that relate

January 13, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 13, 2025 Cognition Therapeu

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 13, 2025 Cognition Therapeutics, Inc.

December 18, 2024 EX-99.1

Topline Results Phase 2 Study of CT1812 in Mild-to-Moderate Dementia with Lewy Bodies December 18, 2024 Director of the Comprehensive Center for Brain Health University of Miami Miller School of Medicine Director at Large of the LBDA Board of Directo

Exhibit 99.1 1 FORWARD-LOOKING STATEMENTS This presentation contains forward-looking statements within the meaning of The Private Securities Litigation Reform Act of 1995. All statements contained in this presentation, other than statements of historical facts or statements that relate to present facts or current conditions, including but not limited to, product candidates, including CT1812, and a

December 18, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 18, 2024 Cognition Therape

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 18, 2024 Cognition Therapeutics, Inc.

November 13, 2024 EX-99.1

Cognition Therapeutics Reports Financial Results for the Third Quarter 2024 and Provides Business and Clinical Update - CT1812 slowed cognitive decline by 95% in Alzheimer’s disease patients with lower levels of plasma p-tau217 in a pre-specified ana

Exhibit 99.1 Cognition Therapeutics Reports Financial Results for the Third Quarter 2024 and Provides Business and Clinical Update - CT1812 slowed cognitive decline by 95% in Alzheimer’s disease patients with lower levels of plasma p-tau217 in a pre-specified analysis from Phase 2 SHINE study presented at CTAD - - On track to report topline results from Phase 2 SHIMMER study investigating CT1812 i

November 13, 2024 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 13, 2024 Cognition Therapeutics, Inc.

November 13, 2024 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2024 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Numbe

October 1, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 1, 2024 Cognition Therapeut

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 1, 2024 Cognition Therapeutics, Inc.

October 1, 2024 EX-99.1

Targeting Amyloid Beta Oligomers: A Disruptive Approach to the Treatment of CNS Disorders September 2024 2 FORWARD-LOOKING STATEMENTS This presentation contains forward-looking statements within the meaning of The Private Securities Litigation Reform

Exhibit 99.1 Targeting Amyloid Beta Oligomers: A Disruptive Approach to the Treatment of CNS Disorders September 2024 2 FORWARD-LOOKING STATEMENTS This presentation contains forward-looking statements within the meaning of The Private Securities Litigation Reform Act of 1995. All statements contained in this presentation, other than statements of historical facts or statements that relate to prese

September 13, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 12, 2024 Cognition Therap

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 12, 2024 Cognition Therapeutics, Inc.

August 28, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 28, 2024 Cognition Therapeut

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 28, 2024 Cognition Therapeutics, Inc.

August 28, 2024 EX-99.1

2 FORWARD-LOOKING STATEMENTS This presentation contains forward-looking statements within the meaning of The Private Securities Litigation Reform Act of 1995. All statements contained in this presentation, other than statements of historical facts or

Exhibit 99.1 Targeting Amyloid Beta Oligomers: A Disruptive Approach to the Treatment of Alzheimer’s Disease August 2024 2 FORWARD-LOOKING STATEMENTS This presentation contains forward-looking statements within the meaning of The Private Securities Litigation Reform Act of 1995. All statements contained in this presentation, other than statements of historical facts or statements that relate to pr

August 8, 2024 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 8, 2024 Cognition Therapeutics, Inc.

August 8, 2024 EX-99.1

Cognition Therapeutics Reports Financial Results for the Second Quarter 2024 and Provides Business and Clinical Update - Proof-of-Concept Phase 2 SHINE Trial Demonstrates ~40% Mean Improvement in ADAS-Cog 11 vs Placebo and Consistent Positive Changes

Exhibit 99.1 Cognition Therapeutics Reports Financial Results for the Second Quarter 2024 and Provides Business and Clinical Update - Proof-of-Concept Phase 2 SHINE Trial Demonstrates ~40% Mean Improvement in ADAS-Cog 11 vs Placebo and Consistent Positive Changes Across Multiple Cognitive and Functional Measures - - On Track to Report Topline Results from SHIMMER Study in Mild-to-Moderate DLB by Y

August 8, 2024 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2024 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 00

July 29, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 29, 2024 Cognition Therapeutic

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 29, 2024 Cognition Therapeutics, Inc.

July 29, 2024 EX-99.1

2 FORWARD-LOOKING STATEMENTS This presentation contains forward-looking statements within the meaning of The Private Securities Litigation Reform Act of 1995. All statements contained in this presentation, other than statements of historical facts or

Exhibit 99.1 Results from the Proof-of-Concept Phase 2 ‘SHINE’ Study of CT1812 in Mild-to-Moderate Alzheimer’s Disease July 29, 2024 2 FORWARD-LOOKING STATEMENTS This presentation contains forward-looking statements within the meaning of The Private Securities Litigation Reform Act of 1995. All statements contained in this presentation, other than statements of historical facts or statements that

June 7, 2024 8-K

Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 7, 2024 Cognition Therapeutics, Inc.

May 7, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 7, 2024 Cognition Therapeutics,

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 7, 2024 Cognition Therapeutics, Inc.

May 7, 2024 EX-99.1

Cognition Therapeutics Reports Financial Results for the First Quarter 2024 and Provides Business Update - Topline Results from SHINE Study in Mild-to-Moderate Alzheimer’s Expected Mid-2024 - - SHIMMER Study in Dementia with Lewy Bodies Completed Enr

Exhibit 99.1 Cognition Therapeutics Reports Financial Results for the First Quarter 2024 and Provides Business Update - Topline Results from SHINE Study in Mild-to-Moderate Alzheimer’s Expected Mid-2024 - - SHIMMER Study in Dementia with Lewy Bodies Completed Enrollment of 130 Participants - Purchase, NY – May 7, 2024 – Cognition Therapeutics, Inc. (Nasdaq: CGTX), a clinical stage company developi

May 7, 2024 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2024 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 0

April 26, 2024 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

TABLE OF CONTENTS UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 ☒ Filed by the Registrant ☐ Filed by a Party other than the Registrant Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☒ Defi

April 26, 2024 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 x Filed by the Registrant ¨ Filed by a Party other than the Registrant Check the appropriate box: ¨ Preliminary Proxy Statement ¨ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ¨ Definitive Proxy State

March 26, 2024 EX-97.1

Cognition Therapeutics, Inc.’s Compensation Recovery Policy

Exhibit 97.1 Cognition THERAPEUTICS, INC. COMPENSATION RECOVERY POLICY Adopted as of November 13, 2023 Cognition Therapeutics, Inc., a Delaware corporation (the “Company”), has adopted a Compensation Recovery Policy (this “Policy”) as described below. 1.Overview The Policy sets forth the circumstances and procedures under which the Company shall recover Erroneously Awarded Compensation from Covere

March 26, 2024 S-8

As filed with the Securities and Exchange Commission on March 26, 2024

As filed with the Securities and Exchange Commission on March 26, 2024 Registration No.

March 26, 2024 EX-FILING FEES

Filing Fee Table.

Exhibit 107 Calculation of Filing Fee Tables Form S-8 (Form Type) Cognition Therapeutics, Inc.

March 26, 2024 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 26, 2024 Cognition Therapeutics, Inc.

March 26, 2024 EX-21.1

Subsidiaries of Cognition Therapeutics, Inc.

Exhibit 21.1 List of Subsidiaries Subsidiary Ownership percentage Jurisdiction of incorporation or organization Cognition Therapeutics PTY LTD 100% Australia

March 26, 2024 EX-99.1

Cognition Therapeutics Reports Year End 2023 Financial Results and Provides Business Update - Topline Results from SHINE Study in Mild-to-Moderate Alzheimer’s Expected mid-2024 - - On Track to Report Topline Results from SHIMMER Study in Mild-to-Mode

Exhibit 99.1 Cognition Therapeutics Reports Year End 2023 Financial Results and Provides Business Update - Topline Results from SHINE Study in Mild-to-Moderate Alzheimer’s Expected mid-2024 - - On Track to Report Topline Results from SHIMMER Study in Mild-to-Moderate DLB in 2H 2024 - - 1Q 2024 Capital Raise Extends Cash Runway Through May 2025 - - Webcast Conference Call Scheduled Today at 8:00 a.

March 26, 2024 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2023 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For The Transition Period From To Commission file number: 001-40886 COGNITI

March 13, 2024 424B5

6,571,428 Shares of Common Stock

TABLE OF CONTENTS  Filed Pursuant to Rule 424(b)(5)  Registration Statement No. 333-268992 PROSPECTUS SUPPLEMENT (To Prospectus dated January 3, 2023) 6,571,428 Shares of Common Stock We are offering 6,571,428 shares of our common stock, par value $0.001 per share. Our common stock is listed on The Nasdaq Global Market (Nasdaq) under the symbol “CGTX.” On March 11, 2024, the last reported sale pri

March 13, 2024 8-K

Entry into a Material Definitive Agreement, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 11, 2024 Cognition Therapeutics, Inc.

March 13, 2024 EX-1.1

Underwriting Agreement, dated as of March 11, 2024, by and between Cognition Therapeutics, Inc. and Titan Partners Group LLC, as representative of the underwriters

Exhibit 1.1 Execution Version 6,571,428 SHARES of Common Stock COGNITION THERAPEUTICS, INC. UNDERWRITING AGREEMENT March 11, 2024 Titan Partners Group LLC, a division of American Capital Partners, LLC As the Representative of the Several underwriters, if any, named in Schedule I hereto c/o Titan Partners Group LLC, a division of American Capital Partners, LLC 4 World Trade Center, 29th Floor New Y

March 11, 2024 8-K

Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 11, 2024 Cognition Therapeutics, Inc.

March 11, 2024 424B5

Subject to completion, dated March 11, 2024

TABLE OF CONTENTS The information in this preliminary prospectus supplement and the accompanying prospectus is not complete and may be changed.

February 20, 2024 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 15, 2024 Cognition Therapeutics, Inc.

February 20, 2024 EX-10.1

Form of Performance Restricted Stock Unit Award Agreement

Exhibit 10.1 COGNITION THERAPEUTICS, INC. 2021 EQUITY INCENTIVE PLAN PERFORMANCE RESTRICTED STOCK UNIT GRANT NOTICE AND AWARD AGREEMENT Cognition Therapeutics, Inc., a Delaware corporation (the “Company”), pursuant to its 2021 Equity Incentive Plan (the “Plan”), hereby grants to the individual listed below (the “Participant”) the number of performance restricted stock units set forth below (the “P

February 7, 2024 SC 13G/A

CGTX / Cognition Therapeutics, Inc. / HIRSCHMAN ORIN Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G/A Amendment No. 2 Under the Securities Exchange Act of 1934 Cognition Therapeutics, Inc. (Name of Issuer) Common Shares (Title of Class of Securities) 19243B102 (CUSIP Number) January 30, 2024 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which

January 19, 2024 SC 13G

CGTX / Cognition Therapeutics, Inc. / PATHSTONE FAMILY OFFICE, LLC - PATHSTONE FAMILY OFFICE, LLC Passive Investment

SC 13G 1 cgtx11824.htm PATHSTONE FAMILY OFFICE, LLC UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 COGNITION THERAPEUTICS INC (Name of Issuer) Common stock (Title of Class of Securities) 19243B102 (CUSIP Number) October 13, 2023 (Date of Event which Requires Filing of this Statement) Check the appropriate box to design

January 8, 2024 424B4

6,030,532 Shares of Common Stock

TABLE OF CONTENTS  Filed Pursuant to Rule 424(b)(4)  File Number 333-276316 PRELIMINARY PROSPECTUS 6,030,532 Shares of Common Stock This prospectus relates to the offer and resale of up to an aggregate of 6,030,532 shares of our common stock, par value $0.

January 4, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 4, 2024 Cognition Therapeut

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 4, 2024 Cognition Therapeutics, Inc.

January 4, 2024 EX-99.1

Disease-modifying medicines for neurodegenerative disorders January 2024 2 FORWARD-LOOKING STATEMENTS This presentation contains forward-looking statements within the meaning of The Private Securities Litigation Reform Act of 1995. All statements con

Exhibit 99.1 Disease-modifying medicines for neurodegenerative disorders January 2024 2 FORWARD-LOOKING STATEMENTS This presentation contains forward-looking statements within the meaning of The Private Securities Litigation Reform Act of 1995. All statements contained in this presentation, other than statements of historical facts or statements that relate to present facts or current conditions,

January 4, 2024 CORRESP

Cognition Therapeutics, Inc. 2500 Westchester Ave. Purchase, New York 10577

Cognition Therapeutics, Inc. 2500 Westchester Ave. Purchase, New York 10577 January 4, 2024 VIA EDGAR U.S. Securities and Exchange Commission Division of Corporation Finance Office of Life Sciences 100 F Street, NE Washington, D.C. 20549 Attention: Tim Buchmiller Re: Cognition Therapeutics, Inc. Registration Statement on Form S-3 Filed December 29, 2023 (File No. 333-276316) Ladies and Gentlemen:

December 29, 2023 S-3

As filed with the Securities and Exchange Commission on December 29, 2023

TABLE OF CONTENTS As filed with the Securities and Exchange Commission on December 29, 2023 Registration No.

December 29, 2023 EX-FILING FEES

Filing Fee Table (filed herewith).

Exhibit 107 Calculation of Filing Fee Tables Form S-3 (Form Type) Cognition Therapeutics, Inc.

November 13, 2023 EX-99.2

Exhibit 99.2: Power of Attorney

EX-99.2 3 tm2330603d1ex99-2.htm EXHIBIT 99.2 Exhibit 99.2 POWER OF ATTORNEY The undersigned hereby constitute and appoint Daniel Schwarz, the lawful attorney-in-fact and agent with full power and authority to execute and file on the undersigned’s behalf, any and all instruments including Forms 3, 4 and 5, and Schedules 13D and 13G (collectively, the “Filings”), and any amendments, supplements or s

November 13, 2023 SC 13D/A

CGTX / Cognition Therapeutics Inc / BIOS Memory SPV I, LP - SC 13D/A Activist Investment

SC 13D/A 1 tm2330603d1sc13da.htm SC 13D/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D/A Under the Securities Exchange Act of 1934 (Amendment No. 3) Cognition Therapeutics, Inc. (Name of Issuer) Common Stock, par value $0.001 per share (Title of Class of Securities) 19243B 102 (CUSIP Number) Bios Equity Partners, LP 1751 River Run, Suite 400 Fort Worth, Texa

November 13, 2023 EX-99.1

Exhibit 99.1 : Joint Filing Agreement

EX-99.1 2 tm2330603d1ex99-1.htm EXHIBIT 99.1 Exhibit 99.1 JOINT FILING AGREEMENT In accordance with Rule 13d-1(k) promulgated under the Securities Exchange Act of 1934, as amended, the undersigned hereby agree to the joint filing with all other Reporting Persons (as such term is defined in the Schedule 13D referred to below) on behalf of each of them of a statement on Schedule 13D (including amend

November 2, 2023 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2023 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Numbe

November 2, 2023 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 2, 2023 Cognition Therapeutics, Inc.

November 2, 2023 EX-99.1

Cognition Therapeutics Reports Third Quarter 2023 Financial Results and Provides Business Update Phase 2 trials in mild-to-moderate Alzheimer’s disease and dementia with Lewy bodies advancing Clinical site initiation underway in 540-patient early sta

Exhibit 99.1 Cognition Therapeutics Reports Third Quarter 2023 Financial Results and Provides Business Update Phase 2 trials in mild-to-moderate Alzheimer’s disease and dementia with Lewy bodies advancing Clinical site initiation underway in 540-patient early stage Alzheimer’s disease START trial; will permit approved monoclonal antibody (lecanemab) as combination therapy Complete data from CT1812

September 12, 2023 8-K

Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 12, 2023 Cognition Therapeutics, Inc.

September 12, 2023 EX-99.1

Disease - modifying medicines for neurodegenerative disorders September 9, 2023

Exhibit 99.1 Disease - modifying medicines for neurodegenerative disorders September 9, 2023 2 FORWARD - LOOKING STATEMENTS This presentation contains forward - looking statements within the meaning of The Private Securities Litigation Reform Act of 1995 . All statements contained in this presentation, other than statements of historical facts or statements that relate to prese nt that relate to p

August 24, 2023 EX-99.1

2 Confidential • Why we work in age-related neurodegenerative conditions • What we are doing to prepare for Phase 3 clinical trials & commercialization • How we fund our company Agenda for Investor Discussion 3 Confidential FORWARD-LOOKING STATEMENTS

Exhibit 99.1 Disease-modifying medicines for neurodegenerative disorders Perspective from a pre-Commercial Company August 2023 2 Confidential • Why we work in age-related neurodegenerative conditions • What we are doing to prepare for Phase 3 clinical trials & commercialization • How we fund our company Agenda for Investor Discussion 3 Confidential FORWARD-LOOKING STATEMENTS This presentation cont

August 24, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 24, 2023 Cognition Therapeut

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 24, 2023 Cognition Therapeutics, Inc.

August 8, 2023 EX-99.1

Cognition Therapeutics Reports Second Quarter 2023 Financial Results and Business Update Announced Positive Topline Results from CT1812 Phase 2 SEQUEL Study in Mild-to-Moderate Alzheimer’s Disease Commenced Recruitment for 540-patient Phase 2 START T

Exhibit 99.1 Cognition Therapeutics Reports Second Quarter 2023 Financial Results and Business Update Announced Positive Topline Results from CT1812 Phase 2 SEQUEL Study in Mild-to-Moderate Alzheimer’s Disease Commenced Recruitment for 540-patient Phase 2 START Trial in Early Alzheimer’s Disease Published Data from SNAP Study Affirming Target Engagement of Sigma-2 (σ-2) Receptor Patient Dosing Com

August 8, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 8, 2023 Cognition Therapeuti

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 8, 2023 Cognition Therapeutics, Inc.

August 8, 2023 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2023 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 00

June 28, 2023 EX-99.2

2 FORWARD-LOOKING STATEMENTS This presentation contains forward-looking statements within the meaning of The Private Securities Litigation Reform Act of 1995. All statements contained in this presentation, other than statements of historical facts or

Exhibit 99.2 SEQUEL (COG0202) Topline Results A Pilot Electroencephalography (EEG) Study to Evaluate the Effect of CT1812 Treatment on Synaptic Activity in Subjects with Mild to Moderate Alzheimer’s Disease 2 FORWARD-LOOKING STATEMENTS This presentation contains forward-looking statements within the meaning of The Private Securities Litigation Reform Act of 1995. All statements contained in this p

June 28, 2023 EX-99.1

Cognition Therapeutics Announces Positive Topline Results for CT1812 Phase 2 SEQUEL Study for Mild-to-Moderate Alzheimer’s Disease Results Show Positive Treatment Effect of CT1812 on Global and Regional Brain Activity Management Holding Webcast Confe

Exhibit 99.1 Cognition Therapeutics Announces Positive Topline Results for CT1812 Phase 2 SEQUEL Study for Mild-to-Moderate Alzheimer’s Disease Results Show Positive Treatment Effect of CT1812 on Global and Regional Brain Activity Management Holding Webcast Conference Call at 8:00am ET Today NEW YORK, NY, June 28, 2023 — Cognition Therapeutics, Inc. (NASDAQ: CGTX), a clinical-stage neuroscience co

June 28, 2023 8-K

Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 28, 2023 Cognition Therapeutics, Inc.

June 28, 2023 424B5

Up to $40,000,000 Common Stock

Filed Pursuant to Rule 424(b)(5) Registration No. 333-268992 PROSPECTUS SUPPLEMENT (To Prospectus dated January 3, 2023, as supplemented by Prospectus Supplement dated March 27, 2023) Up to $40,000,000 Common Stock This prospectus supplement amends and supplements the information in the prospectus, dated January 3, 2023, filed with the Securities and Exchange Commission as a part of our registrati

June 12, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 9, 2023 Cognition Therapeutics

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 9, 2023 Cognition Therapeutics, Inc.

May 4, 2023 EX-99.1

Cognition Therapeutics Reports First Quarter 2023 Financial Results and Provides Business Update Completed enrollment for Phase 2 SEQUEL trial in mild-to-moderate Alzheimer’s disease (AD); topline results expected 2Q 2023 SHINE (AD) trial currently e

Exhibit 99.1 Cognition Therapeutics Reports First Quarter 2023 Financial Results and Provides Business Update Completed enrollment for Phase 2 SEQUEL trial in mild-to-moderate Alzheimer’s disease (AD); topline results expected 2Q 2023 SHINE (AD) trial currently enrolling patients with first patient in Spain enrolled. Expect full enrollment by end of 2023 Received FDA clearance to proceed with 540-

May 4, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 4, 2023 Cognition Therapeutics,

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 4, 2023 Cognition Therapeutics, Inc.

May 4, 2023 EX-3.1

Second Amended and Restated Bylaws of Cognition Therapeutics, Inc.

Exhibit 3.1 SECOND AMENDED AND RESTATED BYLAWS OF COGNITION THERAPEUTICS, INC. (the “Corporation”) ARTICLE I Stockholders Section 1.1.Annual Meeting. The annual meeting of stockholders (any such meeting being referred to in these Bylaws as an “Annual Meeting”) shall be held at the hour, date and place within or without the United States which is fixed by the Corporation’s Board of Directors (the “

May 4, 2023 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2023 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 0

May 1, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 1, 2023 Cognition Therapeutics,

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 1, 2023 Cognition Therapeutics, Inc.

May 1, 2023 EX-10.1

Employment Agreement, dated April 17, 2023, between Cognition Therapeutics, Inc. and John Doyle

Exhibit 10.1 EXECUTIVE EMPLOYMENT AGREEMENT This Executive Employment Agreement (the “Agreement”), dated April 17, 2023, is made and entered into by and between COGNITION THERAPEUTICS, INC., a Delaware corporation (the “Company”) and John Doyle (“Executive”), and will become effective as of May 1, 2023 (the “Effective Date”). Introduction WHEREAS, the Company desires to employ Executive and Execut

April 24, 2023 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

TABLE OF CONTENTS UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 ☒ Filed by the Registrant ☐ Filed by a Party other than the Registrant Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☒ Defi

April 24, 2023 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 x Filed by the Registrant ¨ Filed by a Party other than the Registrant Check the appropriate box: ¨ Preliminary Proxy Statement ¨ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ¨ Definitive Proxy State

April 19, 2023 EX-99.1

2 FORWARD-LOOKING STATEMENTS This presentation contains forward-looking statements within the meaning of The Private Securities Litigation Reform Act of 1995. All statements contained in this presentation, other than statements of historical facts or

Exhibit 99.1 Developing disease-modifying medicines for degenerative disorders Analyst Breakfast April 2023 2 FORWARD-LOOKING STATEMENTS This presentation contains forward-looking statements within the meaning of The Private Securities Litigation Reform Act of 1995. All statements contained in this presentation, other than statements of historical facts or statements that relate to present facts o

April 19, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 19, 2023 Cognition Therapeuti

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 19, 2023 Cognition Therapeutics, Inc.

March 28, 2023 EX-99.1

Cognition Therapeutics Presents Proteomic Biomarker Data Demonstrating Prominent Effects of CT1812 in Altering Underlying Alzheimer’s Disease Processes

Exhibit 99.1 Cognition Therapeutics Presents Proteomic Biomarker Data Demonstrating Prominent Effects of CT1812 in Altering Underlying Alzheimer’s Disease Processes NEW YORK, NY, March 28, 2023 — Cognition Therapeutics, Inc. (NASDAQ: CGTX) presented results of a meta-analysis from the first cohort (SHINE-A) of 24 participants in the Phase 2 SHINE (COG0201; NCT03507790) and the complete dataset fro

March 28, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 28, 2023 Cognition Therapeuti

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 28, 2023 Cognition Therapeutics, Inc.

March 27, 2023 424B5

Up to $16,741,022 Common Stock

Filed Pursuant to Rule 424(b)(5) Registration No. 333-268992 PROSPECTUS SUPPLEMENT (To Prospectus dated January 3, 2023) Up to $16,741,022 Common Stock This prospectus supplement amends and supplements the information in the prospectus, dated January 3, 2023, filed with the Securities and Exchange Commission as a part of our registration statement on Form S-3 (File No. 333-268992) (the “Prospectus

March 23, 2023 EX-FILING FEES

Filing Fee Table.

Exhibit 107 Calculation of Filing Fee Tables Form S-8 (Form Type) Cognition Therapeutics, Inc.

March 23, 2023 S-8

As filed with the Securities and Exchange Commission on March 23, 2023

S-8 1 tm2310086d1s8.htm FORM S-8 As filed with the Securities and Exchange Commission on March 23, 2023 Registration No. 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM S-8 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 COGNITION THERAPEUTICS, INC. (Exact name of registrant as specified in its charter) Delaware 13-4365359 (State or other jurisdiction of inc

March 23, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 23, 2023 Cognition Therapeuti

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 23, 2023 Cognition Therapeutics, Inc.

March 23, 2023 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2022 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For The Transition Period From To Commission file number: 001-40886 COGNITI

March 23, 2023 EX-99.1

Cognition Therapeutics Reports Year End 2022 Financial Results and Provides Business Update - Completed enrollment of CT1812 Phase 2 SEQUEL study for mild-to-moderate Alzheimer's disease - Received FDA clearance for Phase 2 START Study of CT1812 in e

Exhibit 99.1 Cognition Therapeutics Reports Year End 2022 Financial Results and Provides Business Update - Completed enrollment of CT1812 Phase 2 SEQUEL study for mild-to-moderate Alzheimer's disease - Received FDA clearance for Phase 2 START Study of CT1812 in early Alzheimer’s disease - Received FDA clearance for IND for Phase 2 study of CT1812 in 240 patients with geographic atrophy secondary t

March 23, 2023 EX-21.1

Subsidiaries of Cognition Therapeutics, Inc.

Exhibit 21.1 List of Subsidiaries Subsidiary Ownership percentage Jurisdiction of incorporation or organization Cognition Therapeutics PTY LTD 100% Australia

March 15, 2023 EX-99.1

Cognition Therapeutics Announces Development Plans for Oral CT1812 in Geographic Atrophy Secondary to Dry AMD

Exhibit 99.1 Cognition Therapeutics Announces Development Plans for Oral CT1812 in Geographic Atrophy Secondary to Dry AMD NEW YORK, NY, March 15, 2023 — Cognition Therapeutics, Inc. (NASDAQ: CGTX) announced that its Investigational New Drug (IND) application for investigation of CT1812 for geographic atrophy (GA) secondary to dry age-related macular degeneration (dry AMD) has been cleared by the

March 15, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 15, 2023 Cognition Therapeuti

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 15, 2023 Cognition Therapeutics, Inc.

March 10, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 10, 2023 Cognition Therapeuti

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 10, 2023 Cognition Therapeutics, Inc.

March 10, 2023 424B5

Up to $35,000,000 of Shares of Common Stock and 189,856 Shares of Common Stock

TABLE OF CONTENTS   Filed Pursuant to Rule 424(b)(5)   Registration Statement No. 333-268992 PROSPECTUS SUPPLEMENT (To Prospectus dated January 3, 2023) Up to $35,000,000 of Shares of Common Stock and 189,856 Shares of Common Stock This prospectus supplement relates to the issuance and sale of up to $35,000,000 of shares of our common stock that we may sell to Lincoln Park Capital Fund, LLC (“Linc

March 10, 2023 EX-10.2

Registration Rights Agreement, dated as of March 10, 2023, by and between Cognition Therapeutics, Inc. and Lincoln Park Capital Fund, LLC

Exhibit 10.2 REGISTRATION RIGHTS AGREEMENT THIS REGISTRATION RIGHTS AGREEMENT (this “Agreement”), dated as of March 10, 2023, is entered into by and between COGNITION THERAPEUTICS, INC., a Delaware corporation (the “Company”), and LINCOLN PARK CAPITAL FUND, LLC, an Illinois limited liability company (together with its permitted assigns, the “Investor”). Capitalized terms used herein and not otherw

March 10, 2023 EX-10.1

Purchase Agreement, dated as of March 10, 2023, by and between Cognition Therapeutics, Inc. and Lincoln Park Capital Fund, LLC

Exhibit 10.1 PURCHASE AGREEMENT THIS PURCHASE AGREEMENT (the "Agreement"), dated as of March 10, 2023, is made by and between Cognition Therapeutics, Inc., a Delaware corporation (the "Company"), and LINCOLN PARK CAPITAL FUND, LLC, an Illinois limited liability company (the "Investor"). WHEREAS: Subject to the terms and conditions set forth in this Agreement, the Company wishes to sell to the Inve

March 10, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 10, 2023 Cognition Therapeuti

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 10, 2023 Cognition Therapeutics, Inc.

February 22, 2023 EX-99.1

Cognition Therapeutics and ACTC Receive FDA Clearance for Phase 2 START Study of Oral CT1812 in Early Alzheimer’s Disease

Exhibit 99.1 Cognition Therapeutics and ACTC Receive FDA Clearance for Phase 2 START Study of Oral CT1812 in Early Alzheimer’s Disease NEW YORK, NY, February 22, 2023 — Cognition Therapeutics, Inc. (NASDAQ: CGTX) announced that it has cleared the U.S. Food and Drug Administration comment period and may now proceed with the 540-patient Phase 2 START study of CT1812 in adults with mild cognitive imp

February 22, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 22, 2023 Cognition Therape

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 22, 2023 Cognition Therapeutics, Inc.

February 15, 2023 SC 13G/A

CGTX / Cognition Therapeutics Inc / HIRSCHMAN ORIN Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G/A Amendment No. 1 Under the Securities Exchange Act of 1934 Cognition Therapeutics, Inc. (Name of Issuer) Common Shares (Title of Class of Securities) 19243B102 (CUSIP Number) December 31, 2022 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which

February 13, 2023 8-K

Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 27, 2023 Cognition Therapeutics, Inc.

December 29, 2022 CORRESP

Cognition Therapeutics, Inc. 2500 Westchester Ave. Purchase, New York 10577

Cognition Therapeutics, Inc. 2500 Westchester Ave. Purchase, New York 10577 December 29, 2022 VIA EDGAR U.S. Securities and Exchange Commission Division of Corporation Finance Office of Life Sciences 100 F Street, NE Washington, D.C. 20549 Attention: Tim Buchmiller Re: Cognition Therapeutics, Inc. Registration Statement on Form S-3 Filed December 23, 2022 (File No. 333-268992) Ladies and Gentlemen

December 23, 2022 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 23, 2022 Cognition Therape

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 23, 2022 Cognition Therapeutics, Inc.

December 23, 2022 EX-1.2

Controlled Equity OfferingSM Sales Agreement, dated December 23, 2022, by and among the registrant, Cantor Fitzgerald & Co. and B. Riley Securities, Inc.

EX-1.2 2 tm2233311d2ex1-2.htm EXHIBIT 1.2 Exhibit 1.2 Execution Version COGNITION THERAPEUTICS, INC. Shares of Common Stock (par value $0.001 per share) Controlled Equity OfferingSM Sales Agreement December 23, 2022 Cantor Fitzgerald & Co. 499 Park Avenue New York, NY 10022 B. Riley Securities, Inc. 299 Park Avenue, 21st Floor New York, NY 10171 Ladies and Gentlemen: Cognition Therapeutics, Inc.,

December 23, 2022 EX-4.4

Form of Indenture

Exhibit 4.4 COGNITION THERAPEUTICS, INC. INDENTURE Dated as of [ ? ], 20[ ? ] [ ? ] Trustee TABLE OF CONTENTS Page ARTICLE I. DEFINITIONS AND INCORPORATION BY REFERENCE 1 Section 1.1. Definitions 1 Section 1.2. Other Definitions 3 Section 1.3. Incorporation by Reference of Trust Indenture Act 4 Section 1.4. Rules of Construction 4 ARTICLE II. THE SECURITIES 4 Section 2.1. Issuable in Series 4 Sect

December 23, 2022 EX-10.1

Controlled Equity OfferingSM Sales Agreement, dated as of December 23, 2022, by and among Cognition Therapeutics, Inc., Cantor Fitzgerald & Co. and B. Riley Securities, Inc.

Exhibit 10.1 Execution Version COGNITION THERAPEUTICS, INC. Shares of Common Stock (par value $0.001 per share) Controlled Equity OfferingSM Sales Agreement December 23, 2022 Cantor Fitzgerald & Co. 499 Park Avenue New York, NY 10022 B. Riley Securities, Inc. 299 Park Avenue, 21st Floor New York, NY 10171 Ladies and Gentlemen: Cognition Therapeutics, Inc., a Delaware corporation (the ?Company?), c

December 23, 2022 S-3

As filed with the Securities and Exchange Commission on December 23, 2022

TABLE OF CONTENTS As filed with the Securities and Exchange Commission on December 23, 2022 Registration No.

December 23, 2022 EX-FILING FEES

Filing Fee Table (filed herewith).

Exhibit 107 Calculation of Filing Fee Tables Form S-3 (Form Type) Cognition Therapeutics, Inc.

December 5, 2022 SC 13D/A

CGTX / Cognition Therapeutics Inc / BIOS Memory SPV I, LP - SC 13D/A Activist Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D/A Under the Securities Exchange Act of 1934 (Amendment No. 2) Cognition Therapeutics, Inc. (Name of Issuer) Common Stock, par value $0.001 per share (Title of Class of Securities) 19243B 102 (CUSIP Number) Bios Equity Partners, LP 1751 River Run, Suite 400 Fort Worth, Texas 76107 Tel: (817) 984-9197 With a Copy to

November 18, 2022 SC 13G

CGTX / Cognition Therapeutics Inc / HIRSCHMAN ORIN Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Cognition Therapeutics, Inc. (Name of Issuer) Common Shares (Title of Class of Securities) 19243B102 (CUSIP Number) November 10, 2022 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which this Schedule is

November 16, 2022 EX-99.1

2 FORWARD - LOOKING STATEMENTS This presentation contains forward - looking statements within the meaning of The Private Securities Litigation Reform Act of 1995 . All statements contained in this presentation, other than statements of historical fac

Exhibit 99.1 Developing disease - modifying medicines for degenerative disorders November 2022 2 FORWARD - LOOKING STATEMENTS This presentation contains forward - looking statements within the meaning of The Private Securities Litigation Reform Act of 1995 .. All statements contained in this presentation, other than statements of historical facts or statements that relate to present facts or curre

November 16, 2022 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 16, 2022 Cognition Therape

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 16, 2022 Cognition Therapeutics, Inc.

November 14, 2022 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents ? ? UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.

November 14, 2022 EX-99.1

Cognition Therapeutics Reports Third Quarter 2022 Financial Results and Provides Business Update - SHINE Alzheimer’s Trial Expands to European Sites - - SEQUEL Alzheimer’s Trial Awarded Additional NIA Grant to Complete - - Over 50% of SHIMMER Dementi

Exhibit 99.1 Cognition Therapeutics Reports Third Quarter 2022 Financial Results and Provides Business Update - SHINE Alzheimer?s Trial Expands to European Sites - - SEQUEL Alzheimer?s Trial Awarded Additional NIA Grant to Complete - - Over 50% of SHIMMER Dementia with Lewy Bodies Study Sites Active - Purchase, NY ? November 14, 2022 ? Cognition Therapeutics, Inc. (Nasdaq: CGTX), (the ?Company? or

November 14, 2022 EX-1.1

Underwriting Agreement by and between Cognition Therapeutics, Inc. and Cantor Fitzgerald & Co., dated November 10, 2022.

Exhibit 1.1 COGNITION THERAPEUTICS, INC. 5,000,000 Shares of Common Stock (par value $0.001 per share) Underwriting Agreement November 10, 2022 Cantor Fitzgerald & Co. As Representative of the several Underwriters listed in Schedule A Hereto c/o Cantor Fitzgerald & Co. 499 Park Avenue New York, NY 10022 Ladies and Gentlemen: Cognition Therapeutics, Inc., a Delaware corporation (the ?Company?), pro

November 14, 2022 EX-99.2

PURCHASE, N.Y., Nov. 10, 2022 -- Cognition Therapeutics, Inc., (Nasdaq: CGTX), (the Company” or “Cognition”) announced today the pricing of the public offering of 5,000,000 shares of its common stock, at a public offering price of $1.20 per share, fo

Exhibit 99.2 PURCHASE, N.Y., Nov. 10, 2022 - Cognition Therapeutics, Inc., (Nasdaq: CGTX), (the Company? or ?Cognition?) announced today the pricing of the public offering of 5,000,000 shares of its common stock, at a public offering price of $1.20 per share, for gross proceeds of approximately $6.0 million, before deducting underwriting discounts and commissions and offering-related expenses. The

November 14, 2022 8-K

Entry into a Material Definitive Agreement, Financial Statements and Exhibits, Results of Operations and Financial Condition, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 10, 2022 Cognition Therapeutics, Inc.

November 14, 2022 424B4

5,000,000 Shares of Common Stock

TABLE OF CONTENTS  Filed Pursuant to Rule 424(b)(4)  Registration Statement No. 333-268228 PROSPECTUS 5,000,000 Shares of Common Stock We are offering 5,000,000 shares of our common stock at a public offering price of $1.20 per share. Our common stock is listed on the Nasdaq Global Market under the symbol “CGTX.” We are an “emerging growth company” and a “smaller reporting company” as defined unde

November 7, 2022 S-1

As filed with the Securities and Exchange Commission on November 7, 2022.

TABLE OF CONTENTS As filed with the Securities and Exchange Commission on November 7, 2022.

November 7, 2022 EX-10.29

Office Lease Agreement, dated August 31, 2022

Exhibit 10.29 OFFICE LEASE AGREEMENT between RJ EQUITIES LP (Landlord) and COGNITION THERAPEUTICS, INC. (Tenant) Dated: August 31, 2022 TABLE OF CONTENTS ARTICLE 1. BASIC TERMS 1 ARTICLE 2. PREMISES 2 ARTICLE 3. TERM AND COMMENCEMENT 2 ARTICLE 4. CONSTRUCTION OF PREMISES 4 ARTICLE 5. BASE RENT 4 ARTICLE 6. RENT ESCALATION 5 ARTICLE 7. LATE PAYMENT 9 ARTICLE 8. USE OF PREMISES 9 ARTICLE 9. COMMON A

November 7, 2022 EX-FILING FEES

Filing Fee Table.

Exhibit 107 CALCULATION OF REGISTRATION FEE Security Type Security Class Title Fee Calculation Rule Maximum Aggregate Offering Price(1)(2) Fee Rate Amount of Registration Fee Equity Common stock, $0.

November 7, 2022 CORRESP

Cognition Therapeutics, Inc. 2500 Westchester Ave. Purchase, New York 10577

Cognition Therapeutics, Inc. 2500 Westchester Ave. Purchase, New York 10577 November 7, 2022 VIA EDGAR U.S. Securities and Exchange Commission Division of Corporation Finance Office of Life Sciences 100 F Street, NE Washington, D.C. 20549 Attention: Joshua Gorsky Re: Cognition Therapeutics, Inc. Registration Statement on Form S-1, filed November 7, 2022 Ladies and Gentlemen: Pursuant to Rule 461 o

November 7, 2022 CORRESP

[Signature Page Follows]

November 7, 2022 VIA EDGAR Securities and Exchange Commission Division of Corporation Finance Office of Life Sciences 100 F Street, N.

November 7, 2022 EX-1.1

Form of Underwriting Agreement.

  Exhibit 1.1   COGNITION THERAPEUTICS, INC. [] Shares of Common Stock (par value $0.001 per share)   Underwriting Agreement   November [], 2022   Cantor Fitzgerald & Co. As Representative of the several Underwriters listed in Schedule A Hereto   c/o Cantor Fitzgerald & Co. 499 Park Avenue New York, NY 10022   Ladies and Gentlemen:   Cognition Therapeutics, Inc., a Delaware corporation (the “Compa

October 20, 2022 DRS

Confidential Treatment Requested by Cognition Therapeutics, Inc. Pursuant to 17 C.F.R. Section 200.83 As confidentially submitted to the Securities and Exchange Commission on October 20, 2022. This draft registration statement has not been publicly f

TABLE OF CONTENTS Confidential Treatment Requested by Cognition Therapeutics, Inc.

August 29, 2022 8-K

Regulation FD Disclosure, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 29, 2022 Cognition Therapeutics, Inc.

August 29, 2022 EX-99.1

Developing disease- modifying medicines for degenerative disorders August 2022 2 This presentation contains forward-looking statements within the meaning of The Private Securities Litigation Reform Act of 1995. All statements contained in this presen

Exhibit 99.1 Developing disease- modifying medicines for degenerative disorders August 2022 2 This presentation contains forward-looking statements within the meaning of The Private Securities Litigation Reform Act of 1995. All statements contained in this presentation, other than statements of historical facts or statements that relate to present facts or current conditions, including but not lim

August 9, 2022 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents ? ? UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.

August 9, 2022 EX-99.1

Cognition Therapeutics Reports Second Quarter 2022 Financial Results and Provides Business Update Ongoing patient dosing in SHIMMER Study for DLB and SHINE Study for Alzheimer’s Disease Positive Preliminary Data for Dry AMD Program Presented at ARVO

Exhibit 99.1 Cognition Therapeutics Reports Second Quarter 2022 Financial Results and Provides Business Update Ongoing patient dosing in SHIMMER Study for DLB and SHINE Study for Alzheimer?s Disease Positive Preliminary Data for Dry AMD Program Presented at ARVO 2022 Proteomics Data from SPARC read out at AAIC PURCHASE, NY, August 9, 2022 ? Cognition Therapeutics, Inc. (NASDAQ: CGTX) (the ?Company

August 9, 2022 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 9, 2022 Cognition Therapeutics, Inc.

July 27, 2022 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 21, 2022 Cognition Therapeutics, Inc.

June 16, 2022 8-K

Regulation FD Disclosure, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 16, 2022 Cognition Therapeutics, Inc.

June 16, 2022 EX-99.1

Disease - modifying medicines for degenerative disorders JMP Securities Life Sciences Conference June 16, 2022

Exhibit 99.1 Disease - modifying medicines for degenerative disorders JMP Securities Life Sciences Conference June 16, 2022 2 This presentation contains forward - looking statements within the meaning of The Private Securities Litigation Reform Act of 1995 . All statements contained in this presentation, other than statements of historical facts or statements that relate to present facts or curren

June 13, 2022 8-K

Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 10, 2022 Cognition Therapeutics, Inc.

May 11, 2022 EX-99.1

Cognition Therapeutics Reports First Quarter 2022 Financial Results and Provides Business Update Treatment Commences in Second Cohort of Phase 2 SHINE Study in Mild-to-Moderate Alzheimer’s Disease Data Presented at Scientific Conferences Further Vali

Exhibit 99.1 Cognition Therapeutics Reports First Quarter 2022 Financial Results and Provides Business Update Treatment Commences in Second Cohort of Phase 2 SHINE Study in Mild-to-Moderate Alzheimer’s Disease Data Presented at Scientific Conferences Further Validate the Potential of σ-2 Modulators PURCHASE, NY, May 11, 2022 (GLOBE NEWSWIRE) – Cognition Therapeutics, Inc. (NASDAQ: CGTX), a clinica

May 11, 2022 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents ? ? UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.

May 11, 2022 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 11, 2022 Cognition Therapeutics, Inc.

April 25, 2022 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 x Filed by the Registrant ? Filed by a Party other than the Registrant Check the appropriate box: ? Preliminary Proxy Statement ? Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ? Definitive Proxy State

April 25, 2022 DEF 14A

Definitive Proxy Statement on Schedule 14A, filed with the SEC on April 25, 2022;

TABLE OF CONTENTS UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 ? Filed by the Registrant ? ? Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? ? Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2))

March 30, 2022 EX-21.1

Subsidiaries of Cognition Therapeutics, Inc.

Exhibit 21.1 List of Subsidiaries ? Subsidiary Ownership percentage Jurisdiction of incorporation or organization Cognition Therapeutics PTY LTD 100% Australia ?

March 30, 2022 EX-99.1

Cognition Therapeutics Reports Year End 2021 Financial Results and Provides Business Update - Well capitalized from $52 million IPO and $169 million in grant funding - - Established clinical program in Alzheimer’s disease enhanced by new DLB study an

Exhibit 99.1 Cognition Therapeutics Reports Year End 2021 Financial Results and Provides Business Update - Well capitalized from $52 million IPO and $169 million in grant funding - - Established clinical program in Alzheimer?s disease enhanced by new DLB study and dry AMD program - - Conference Call and Live Audio Webcast Scheduled for Wednesday, March 30 at 8:00 a.m. ET - PURCHASE, NY, March 30,

March 30, 2022 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K

Table of Contents ? ? UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.

March 30, 2022 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 30, 2022 Cognition Therapeutics, Inc.

March 30, 2022 EX-4.1

Exhibit 4.1

Exhibit 4.1 DESCRIPTION OF THE REGISTRANT?S SECURITIES REGISTERED PURSUANT TO SECTION 12 OF THE SECURITIES EXCHANGE ACT OF 1934 ? Cognition Therapeutics, Inc. (the ?Company?) has one class of securities registered under Section 12 of the Securities Exchange Act of 1934, as amended (the ?Exchange Act?). The Company?s common stock, $0.001 par value per share (?Common Stock?) is registered under Sect

March 30, 2022 S-8

As filed with the Securities and Exchange Commission on March 30, 2022 Registration No. 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM S-8 REGISTRATION STATEMENT THE SECURITIES ACT OF 1933 COGNITION THERAPEUTICS, INC.

As filed with the Securities and Exchange Commission on March 30, 2022 Registration No.

March 30, 2022 EX-FILING FEES

Filing Fee Table.

Exhibit 107 Calculation of Filing Fee Tables Form S-8 (Form Type) Cognition Therapeutics, Inc.

March 15, 2022 EX-99.2

PROTEOMIC ANALYSIS OF CSF IN A PHASE 2 CLINICAL TRIAL FOR AD TO IDENTIFY PHARMACODYNAMIC BIOMARKERS OF THE S2R MODULATOR CT1812 N. Seyfried1 , L. Waybright2 , D. Duong1 , E. Malagise2 , K. Pandey3 , C. Williams2 , E. Dammer1 , L. Ping4 , K. Blennow5

Exhibit 99.2 PROTEOMIC ANALYSIS OF CSF IN A PHASE 2 CLINICAL TRIAL FOR AD TO IDENTIFY PHARMACODYNAMIC BIOMARKERS OF THE S2R MODULATOR CT1812 N. Seyfried1 , L. Waybright2 , D. Duong1 , E. Malagise2 , K. Pandey3 , C. Williams2 , E. Dammer1 , L. Ping4 , K. Blennow5 , H. Zetterberg6 , J. Lah4 , A. Levey7 , L. Ricciardi2 , A.O. Caggiano2 , Mary E Hamby2 Affiliations: 1Emory University School of Medicin

March 15, 2022 EX-99.1

Exhibit 99.1

Exhibit 99.1 EXPERIMENTAL THERAPEUTIC CT1812 DEMONSTRATES TARGET ENGAGEMENT IN A PHASE 1b CLINICAL TRIAL TO MEASURE DISPLACEMENT OF A? OLIGOMERS INTO CSF NJ Izzo PhD1, KM LaBarbera BS1, CM Yuede PhD2, L Waybright BS1, R Yurko MS1, YI Sheline MD3, HM Edwards BS2, WD Gardiner BS2, K Blennow MD4, H Zetterberg MD4, AB Hanson MD5, CS Davis PhD1, RJ Guttendorf PhD6, LS Schneider MD7, S DeKosky MD8, AO C

March 15, 2022 8-K

Regulation FD Disclosure, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 15, 2022 Cognition Therapeutics, Inc.

February 1, 2022 SC 13D/A

CGTX / Cognition Therapeutics Inc / BIOS Memory SPV I, LP - SC 13D/A Activist Investment

SC 13D/A 1 tm224034d1sc13da.htm SC 13D/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D Under the Securities Exchange Act of 1934 (Amendment No. 1) Cognition Therapeutics, Inc. (Name of Issuer) Common Stock, par value $0.001 per share (Title of Class of Securities) 19243B 102 (CUSIP Number) Bios Equity Partners, LP 1751 River Run, Suite 400 Fort Worth, Texas 7

January 10, 2022 8-K

Regulation FD Disclosure, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 10, 2022 Cognition Therapeutics, Inc.

January 10, 2022 EX-99.1

Disease - modifying medicines for degenerative disorders January 2022

Exhibit 99.1 Disease - modifying medicines for degenerative disorders January 2022 2 This presentation contains forward - looking statements within the meaning of The Private Securities Litigation Reform Act of 1995 . All statements contained in this presentation, other than statements of historical facts or statements that relate to present facts or current conditions, including but not limited t

November 18, 2021 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 18, 2021 Cognition Therapeutics, Inc.

November 18, 2021 EX-99.1

Cognition Therapeutics Reports Third Quarter Financial Results and Company Highlights - Capital from upsized IPO plus substantial NIA grants supports clinical progress of novel small- molecule σ-2 modulators into new indications -

Exhibit 99.1 Cognition Therapeutics Reports Third Quarter Financial Results and Company Highlights - Capital from upsized IPO plus substantial NIA grants supports clinical progress of novel small- molecule ?-2 modulators into new indications - Purchase, NY ? November 18, 2021 ? Cognition Therapeutics, Inc. (Nasdaq: CGTX), a clinical-stage biopharmaceutical company engaged in the discovery and deve

November 17, 2021 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents ? ? UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.

November 12, 2021 8-K

Regulation FD Disclosure

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 10, 2021 Cognition Therapeutics, Inc.

November 3, 2021 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 29, 2021 Cognition Therapeutics, Inc.

November 2, 2021 S-8

Form S-8 (File No. 333-260686) with the Securities and Exchange Commission (the “Commission”) on November 2, 2021

S-8 1 tm2131398d1s8.htm FORM S-8 As filed with the Securities and Exchange Commission on November 2, 2021 File No. 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM S-8 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 COGNITION THERAPEUTICS, INC. (Exact name of registrant as specified in its charter) Delaware 13-4365359 (State or other jurisdiction of incorpora

November 2, 2021 EX-99.7

Form of Stock Option Grant Notice and Award Agreement, under the 2021 Plan.

Exhibit 99.7 COGNITION THERAPEUTICS, INC. 2021 EQUITY INCENTIVE PLAN STOCK OPTION GRANT NOTICE AND AWARD AGREEMENT Cognition Therapeutics, Inc., a Delaware corporation (the ?Company?), pursuant to its 2021 Equity Incentive Plan (the ?Plan?), hereby grants to the individual listed below (?Participant?) an option to purchase the number of Shares set forth below (the ?Option?). The Option described i

November 2, 2021 EX-99.6

Form of Restricted Stock Unit Award Agreement, under the 2021 Plan.

Exhibit 99.6 COGNITION THERAPEUTICS, INC. 2021 EQUITY INCENTIVE PLAN RESTRICTED STOCK UNIT GRANT NOTICE AND AWARD AGREEMENT Cognition Therapeutics, Inc., a Delaware corporation (the ?Company?), pursuant to its 2021 Equity Incentive Plan (the ?Plan?), hereby grants to the individual listed below (?Participant?) the number of restricted stock units set forth below (the ?Restricted Stock Units?). The

October 25, 2021 SC 13D

CGTX / Cognition Therapeutics Inc / BIOS Memory SPV I, LP - SC 13D Activist Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D Under the Securities Exchange Act of 1934 Cognition Therapeutics, Inc. (Name of Issuer) Common Stock, par value $0.001 per share (Title of Class of Securities) 19243B 102 (CUSIP Number) Bios Equity Partners, LP 1751 River Run, Suite 400 Fort Worth, Texas 76107 Tel: (817) 984-9197 With a Copy to: Andrew J. Rosell W

October 14, 2021 8-K

Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 13, 2021 Cognition Therapeutics, Inc.

October 14, 2021 EX-3.1

Third Amended and Restated Certificate of Incorporation of Cognition Therapeutics, Inc.

Exhibit 3.1 Third AMENDED AND RESTATED CERTIFICATE OF INCORPORATION of COGNITION THERAPEUTICS, INC. Cognition Therapeutics, Inc., a corporation organized and existing under the laws of the State of Delaware (the ?Corporation?), hereby certifies as follows: 1. The name of the Corporation is Cognition Therapeutics, Inc. The date of the filing of its original Certificate of Incorporation with the Sec

October 14, 2021 EX-3.2

Amended and Restated Bylaws (incorporated by reference to exhibit 3.2 of the Company’s Current Report on Form 8-K filed on October 14, 2021).

? Exhibit 3.2 ? AMENDED AND RESTATED ? BYLAWS ? OF ? COGNITION THERAPEUTICS, INC. ? (the ?Corporation?) ? Article I Stockholders ? Section 1.1.??????????Annual Meeting. The annual meeting of stockholders (any such meeting being referred to in these Bylaws as an ?Annual Meeting?) shall be held at the hour, date and place within or without the United States which is fixed by the Corporation?s Board

October 12, 2021 424B4

Per share

TABLE OF CONTENTS ?Filed Pursuant to Rule 424(b)(4)? ?Registration No. 333-257999? Prospectus 3,768,116 shares Common stock This is the initial public offering of shares of common stock of Cognition Therapeutics, Inc. We are offering 3,768,116 shares of our common stock. The initial public offering price per share is $12.00. Prior to this offering, there has been no public market for our common st

October 7, 2021 S-1MEF

As filed with the Securities and Exchange Commission on October 7, 2021.

As filed with the Securities and Exchange Commission on October 7, 2021. Registration No. 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM S-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 Cognition Therapeutics, Inc. (Exact name of registrant as specified in its charter) ? Delaware ? ? 2836 ? ? 13-4365359 ? ? (State or other jurisdiction of incorporation

October 6, 2021 8-A12B

The description of our common stock contained in our registration statement on Form 8-A (File No. 001-40886) filed with the SEC on October 6, 2021, under the Exchange Act, including any amendment or report filed for the purpose of updating such description.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-A FOR REGISTRATION OF CERTAIN CLASSES OF SECURITIES PURSUANT TO SECTION 12(b) OR 12(g) OF THE SECURITIES EXCHANGE ACT OF 1934 Cognition Therapeutics, Inc. (Exact name of registrant as specified in its charter) Delaware 13-4365359 (State or other jurisdiction of incorporation or organization) (I.R.S. Employer Identificat

October 5, 2021 CORRESP

October 5, 2021

CORRESP 1 filename1.htm October 5, 2021 VIA EDGAR Securities and Exchange Commission Division of Corporation Finance 100 F Street, N.E. Washington, D.C. 20549 Re: Cognition Therapeutics, Inc. Registration Statement on Form S-1 File No. No. 333-257999 Acceleration Request Requested Date: October 7, 2021 Requested Time: 4:00 p.m. Eastern Time (US) Ladies and Gentlemen: In connection with the above-r

October 5, 2021 CORRESP

Cognition Therapeutics, Inc. 2500 Westchester Ave. Purchase, New York 10577

Cognition Therapeutics, Inc. 2500 Westchester Ave. Purchase, New York 10577 October 5, 2021 VIA EDGAR U.S. Securities and Exchange Commission Division of Corporation Finance Office of Life Sciences 100 F Street, NE Washington, D.C. 20549 Attention: Eric Atallah, Kevin Kuhar, Margaret Schwartz and Celeste Murphy Re: Cognition Therapeutics, Inc. Registration Statement on Form S-1 SEC File No. 333-25

October 4, 2021 EX-10.11

Cognition Therapeutics, Inc. 2021 Equity Incentive Plan

Exhibit 10.11 Cognition THERAPEUTICS, INC. 2021 EQUITY INCENTIVE PLAN Section 1. Purpose; Definitions. The purposes of the Cognition Therapeutics, Inc. 2021 Equity Incentive Plan (as amended from time to time, the ?Plan?) are to: (a) enable Cognition Therapeutics, Inc. (the ?Company?) and its affiliated companies to recruit and retain highly qualified employees, directors and consultants; (b) prov

October 4, 2021 S-1/A

As filed with the Securities and Exchange Commission on October 4, 2021.

TABLE OF CONTENTS As filed with the Securities and Exchange Commission on October 4, 2021.

October 4, 2021 EX-4.1

Specimen Common Stock Certificate of Registrant (incorporated by reference to exhibit 4.1 to the Company’s Registration Statement on Form S-1 (File No. 333-257999) filed July 29, 2021).

Exhibit 4.1 NUMBER SPECIMEN - NOT NEGOTIABLE SPECIMEN not negotiable SHARES COMMON STOCK SEE REVERSE FOR CERTAIN DEFINITIONS INCORPORATED UNDER THE LAWS OF THE STATE OF DELAWARE CUSIP 19243B 10 2 This Certifies That: is the owner of FULLY PAID AND NON-ASSESSABLE SHARES OF COMMON STOCK OF $0.001 PAR VALUE EACH OF Cognition Therapeutics, Inc. transferable on the books of the Corporation by the holde

October 4, 2021 EX-3.6

Fifth Amendment to the Second Amended and Restated Certificate of Incorporation, as filed with the Delaware Secretary of State on October 1, 2021.

Exhibit 3.6 CERTIFICATE OF AMENDMENT to the SECOND AMENDED AND RESTATED CERTIFICATE OF INCORPORATION of COGNITION THERAPEUTICS, INC. COGNITION THERAPEUTICS, INC., a corporation organized and existing under the General Corporation Law of the State of Delaware (the ?Corporation?), does hereby certify as follows: FIRST: The name of the Corporation is Cognition Therapeutics, Inc. The Certificate of In

October 4, 2021 EX-10.12

Cognition Therapeutics, Inc. 2021 Employee Stock Purchase Plan

Exhibit 10.12 Cognition THERAPEUTICS, INC. 2021 EMPLOYEE STOCK PURCHASE PLAN 1. Purpose. The purpose of the Cognition Therapeutics, Inc. 2021 Employee Stock Purchase Plan is to provide employees of the Company and its Participating Subsidiaries with an opportunity to acquire a proprietary interest in the Company through the purchase of shares of Common Stock. The Company intends that the Plan qual

September 10, 2021 S-1/A

As filed with the Securities and Exchange Commission on September 10, 2021.

TABLE OF CONTENTS As filed with the Securities and Exchange Commission on September 10, 2021.

September 10, 2021 CORRESP

1

Troutman Pepper Hamilton Sanders LLP 3000 Two Logan Square, Eighteenth and Arch Streets Philadelphia, PA 19103-2799 troutman.

August 20, 2021 S-1/A

As filed with the Securities and Exchange Commission on August 20, 2021.

TABLE OF CONTENTS As filed with the Securities and Exchange Commission on August 20, 2021.

August 20, 2021 EX-1.1

Form of Underwriting Agreement.

Exhibit 1.1 COGNITION THERAPEUTICS, INC. UNDERWRITING AGREEMENT New York, New York [•], 2021 B. Riley Securities, Inc., As Representative of the Several Underwriters 200 Vesey Street, 25th Floor New York, NY 10281 Ladies and Gentlemen: The undersigned, Cognition Therapeutics, Inc. (together with its affiliates, subsidiaries, predecessors, and successors, the "Company"), a company formed under the

July 29, 2021 EX-10.12

2021 Employee Stock Purchase Plan.

EX-10.12 6 tm2113659d10ex10-12.htm EXHIBIT 10.12 Exhibit 10.12 Cognition THERAPEUTICS, INC. 2021 EMPLOYEE STOCK PURCHASE PLAN 1. Purpose. The purpose of the Cognition Therapeutics, Inc. 2021 Employee Stock Purchase Plan is to provide employees of the Company and its Participating Subsidiaries with an opportunity to acquire a proprietary interest in the Company through the purchase of shares of Com

July 29, 2021 EX-10.21

Employee Restrictive Covenant Agreement

Exhibit 10.21 EMPLOYEE Restrictive Covenant AgreemenT THIS AGREEMENT (the ?Agreement?) is between Cognition Therapeutics, Inc. (the ?Company?), a Delaware corporation with its principal offices at 2500 Westchester Ave., Purchase, NY 10577 and (the ?Employee?), an individual residing at the address set forth on the signature page to this Agreement. Recitals: The parties desire to enter into this Ag

July 29, 2021 S-1/A

As filed with the Securities and Exchange Commission on July 29, 2021.

? As filed with the Securities and Exchange Commission on July 29, 2021. Registration No. 333-257999? ? ? UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Amendment No. 1 to FORM S-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 Cognition Therapeutics, Inc. (Exact name of registrant as specified in its charter) ? Delaware ? ? 2836 ? ? 13-4365359 ? ? (State or other

July 29, 2021 EX-10.1

Form of Indemnification Agreement by and between the Registrant and its individual directors and officers.

Exhibit 10.1 INDEMNIFICATION AGREEMENT THIS INDEMNIFICATION AGREEMENT (the ?Agreement?) is made and entered into effective as of , 2021 between Cognition Therapeutics, Inc., a Delaware corporation (the ?Company?), and (?Indemnitee?). WITNESSETH THAT: WHEREAS, highly competent persons have become more reluctant to serve corporations as directors or in other capacities unless they are provided with

July 29, 2021 EX-3.8

Form of Amended and Restated Bylaws, which will become effective immediately prior to the closing of this offering.

? Exhibit 3.8? ? AMENDED AND RESTATED ? BYLAWS ? OF ? COGNITION THERAPEUTICS, INC. ? (the ?Corporation?) ? Article I Stockholders ? Section 1.1.??????????Annual Meeting. The annual meeting of stockholders (any such meeting being referred to in these Bylaws as an ?Annual Meeting?) shall be held at the hour, date and place within or without the United States which is fixed by the Corporation?s Board

July 29, 2021 EX-3.6

Form of Third Amended and Restated Certificate of Incorporation, which will become effective immediately prior to the closing of this offering.

? Exhibit 3.6? ? Third AMENDED AND RESTATED ? CERTIFICATE OF INCORPORATION ? OF ? COGNITION THERAPEUTICS, INC. ? Cognition Therapeutics, Inc., a corporation organized and existing under the laws of the State of Delaware (the ?Corporation?), hereby certifies as follows: ? 1.?????????????The name of the Corporation is Cognition Therapeutics, Inc. The date of the filing of its original Certificate of

July 29, 2021 EX-10.16

Form of Amended and Restated Employment Agreement by and between the Registrant and Lisa Ricciardi, which will become effective immediately prior to the closing of this offering.

Exhibit 10.16 EXECUTIVE EMPLOYMENT AGREEMENT This Executive Employment Agreement (the ?Agreement?), dated , 20, is made and entered into by and between COGNITION THERAPEUTICS, INC., a Delaware corporation (the ?Company?) and Lisa Ricciardi (?Executive?), and will become effective on the first date that the Company?s common stock is traded on a national stock exchange or national market system (the

July 29, 2021 EX-10.20

Form of Employment Agreement by and between the Registrant and James M. O’Brien, which will become effective immediately prior to the closing of this offering.

Exhibit 10.20 EXECUTIVE EMPLOYMENT AGREEMENT This Executive Employment Agreement (the ?Agreement?), dated , 20, is made and entered into by and between COGNITION THERAPEUTICS, INC., a Delaware corporation (the ?Company?) and James O?Brien (?Executive?), and will become effective on the first date that the Company?s common stock is traded on a national stock exchange or national market system (the

July 29, 2021 EX-10.11

2021 Equity Incentive Plan.

Exhibit 10.11 Cognition THERAPEUTICS, INC. 2021 EQUITY INCENTIVE PLAN Section 1. Purpose; Definitions. The purposes of the Cognition Therapeutics, Inc. 2021 Equity Incentive Plan (as amended from time to time, the ?Plan?) are to: (a) enable Cognition Therapeutics, Inc. (the ?Company?) and its affiliated companies to recruit and retain highly qualified employees, directors and consultants; (b) prov

July 29, 2021 EX-10.22

Option Agreements for Directors

EX-10.22 10 tm2113659d10ex10-22.htm EXHIBIT 10.22 Exhibit 10.22 COGNITION THERAPEUTICS, INC. 2021 EQUITY INCENTIVE PLAN STOCK OPTION GRANT NOTICE AND AWARD AGREEMENT Cognition Therapeutics, Inc., a Delaware corporation (the “Company”), pursuant to its 2021 Equity Incentive Plan (the “Plan”), hereby grants to the individual listed below (“Participant”) an option to purchase the number of Shares set

July 29, 2021 EX-10.24

Letter Agreement between the Registrant and Jack A. Khattar.

EX-10.24 12 tm2113659d10ex10-24.htm EXHIBIT 10.24 Exhibit 10.24 August 14, 2020 Mr. Jack A. Khattar 105 Alderwood Drive Gaithersburg, MD 20878 [email protected] Dear Jack: Following our recent discussions, I am pleased to invite you to join the Board of Directors of Cognition Therapeutics, Inc. (the "Company") as an outside director, subject to election by the Company’s stockholders, on the f

July 29, 2021 CORRESP

1

CORRESP 1 filename1.htm Troutman Pepper Hamilton Sanders LLP 3000 Two Logan Square, Eighteenth and Arch Streets Philadelphia, PA 19103-2799 troutman.com July 29, 2021 VIA EDGAR AND OVERNIGHT MAIL U.S. Securities and Exchange Commission 100 F. Street, N.E. Washington, D.C. 20549 Attention: Eric Atallah, Kevin Kuhar, Margaret Schwartz and Celeste Murphy Re: Cognition Therapeutics, Inc. Registration

July 29, 2021 EX-10.23

Board of Directors of Cognition Therapeutics, Inc. Nomination Letter of Mr. Brett Monia, Ph.D.

EX-10.23 11 tm2113659d10ex10-23.htm EXHIBIT 10.23 Exhibit 10.23 October 22, 2020 Mr. Brett Monia, Ph.D. 2306 Casa Hermosa Court Encinitas, CA 92024 [email protected] Dear Brett: Following our recent discussions, I am pleased to invite you to join the Board of Directors of Cognition Therapeutics, Inc. (the "Company") as an outside director, on the following basis: 1. Position. Upon your acceptanc

July 29, 2021 CORRESP

CERTAIN PORTIONS OF THIS LETTER AS FILED VIA EDGAR HAVE BEEN OMITTED AND FILED SEPARATELY WITH THE SEC. CONFIDENTIAL TREATMENT HAS BEEN REQUESTED WITH RESPECT TO THE OMITTED PORTIONS. OMITTED INFORMATION HAS BEEN REPLACED IN THIS LETTER AS FILED VIA

Troutman Pepper Hamilton Sanders LLP 3000 Two Logan Square, Eighteenth and Arch Streets Philadelphia, PA 19103-2799 Troutman.

July 19, 2021 EX-10.28

Grant Agreement dated August 28, 2020 by and between the Registrant and the National Institute of Aging.

Exhibit 10.28 Notice of Award RESEARCH Department of Health and Human Services National Institutes of Health NATIONAL INSTITUTE ON AGING Federal Award Date: 08/28/2020 Grant Number: 3R01AG058660-03S2 FAIN: R01AG058660 Principal Investigator(s): SUSAN M CATALANO, PHD Project Title: A Randomized, Double-blind, Placebo-Controlled, Parallel-Group, Phase II Study to Evaluate the Safety and Efficacy of

July 19, 2021 EX-10.5

First Amendment to Office Lease dated July 1, 2017, by and between the Registrant and RJ Equities LP.

EX-10.5 11 tm2113659d7ex10-5.htm EXHIBIT 10.5 Exhibit 10.5 FIRST AMENDMENT TO OFFICE LEASE AGREEMENT This First Amendment to Office Lease Agreement (“Amendment”) is made this 1st day of July, 2017, and is by and between RJ EQUITIES LP, a Pennsylvania limited partnership (“Landlord”), and COGNITION THERAPEUTICS, INC., a Delaware corporation (“Tenant”). Article I- AMENDMENT OF BASIC TERMS The partie

July 19, 2021 EX-3.7

Bylaws, dated August 21, 2007, as currently in effect.

EX-3.7 7 tm2113659d7ex3-7.htm EXHIBIT 3.7 Exhibit 3.7 BY-LAWS OF COGNITION THERAPEUTICS, INC. Article 1 OFFICES Section 1.1. The Corporation shall have and maintain in the State of Delaware a registered office which may, but need not be, the same as its place of business. Section 1.2. The Corporation may also have offices at such other places as the Board of Directors may from time to time determi

July 19, 2021 EX-3.3

Second Amendment to Second Amended and Restated Certificate of Incorporation, as filed with the Delaware Secretary of State on dated February 2, 2017.

Exhibit 3.3 SECOND CERTIFICATE OF AMENDMENT OF AMENDED AND RESTATED CERTIFICATE OF INCORPORATION OF COGNITION THERAPEUTICS, INC. Cognition Therapeutics, Inc., a corporation organized and existing under and by virtue of the General Corporation Law of the State of Delaware (the ?DGCL?), DOES HEREBY CERTIFY THAT: FIRST: The Board of Directors (the ?Board?) of Cognition Therapeutics, Inc. (the ?Corpor

July 19, 2021 EX-3.5

Fourth Amendment to Second Amended and Restated Certificate of Incorporation, as filed with the Delaware Secretary of State on dated April 30, 2021.

EX-3.5 6 tm2113659d7ex3-5.htm EXHIBIT 3.5 Exhibit 3.5 FOURTH CERTIFICATE OF AMENDMENT OF SECOND AMENDED AND RESTATED CERTIFICATE OF INCORPORATION OF COGNITION THERAPEUTICS, INC. Cognition Therapeutics, Inc. (the “Corporation”), a corporation organized and existing under and by virtue of the General Corporation Law of the State of Delaware, as the same may be amended from time to time (“DGCL”), DOE

July 19, 2021 EX-10.24

Grant Agreement dated August 14, 2016 by and between the Registrant and the National Institute of Aging.

Exhibit 10.24 Notice of Award Multi-Year Funded Research Project Grant Department of Health and Human Services National Institutes of Health NATIONAL INSTITUTE ON AGING Federal Award Date: 08/14/2016 Grant Number: 1RF1AG054176-01 FAIN: RF1AG054176 Principal Investigator(s): SUSAN M CATALANO, PHD Project Title: Phase 1b first-in-patient safety trial for CT1812, a novel Alzheimer’s synaptic protecti

July 19, 2021 EX-10.7

Amended and Restated 2007 Equity Incentive Plan.

EX-10.7 13 tm2113659d7ex10-7.htm EXHIBIT 10.7 Exhibit 10.7 Effective Date: October 1, 2007 Amended and Restated: January 16, 2009 Amended and Restated: December 14, 2010 Amended and Restated: March 25, 2011 Amended and Restated: November 27, 2011 Amended and Restated: March 20, 2014 Amended and Restated: February 22, 2016 Amended and Restated: October 28, 2016 Amended and Restated: January 10, 201

July 19, 2021 EX-10.13

Form of Restricted Stock Award Agreement.

Exhibit 10.13 COGNITION THERAPEUTICS, INC. 2021 EQUITY INCENTIVE PLAN RESTRICTED STOCK UNIT GRANT NOTICE AND AWARD AGREEMENT Cognition Therapeutics, Inc., a Delaware corporation (the “Company”), pursuant to its 2021 Equity Incentive Plan (the “Plan”), hereby grants to the individual listed below (“Participant”) the number of restricted stock units set forth below (the “Restricted Stock Units”). Th

July 19, 2021 EX-3.1

Second Amended and Restated Certificate of Incorporation, as filed with the Delaware Secretary of State on dated November 14, 2016, as currently in effect.

Exhibit 3.1 SECOND AMENDED AND RESTATED CERTIFICATE OF INCORPORATION OF COGNITION THERAPEUTICS, INC. (incorporated on August 21, 2007) COGNITION THERAPEUTICS, INC., a corporation organized and existing under and by virtue of the provisions of the General Corporation Law of the State of Delaware, as it may be amended from time to time (the “General Corporation Law”), hereby certifies as follows: 1.

July 19, 2021 EX-10.33

Grant Agreement dated May 6, 2021 by and between the Registrant and the National Institute of Aging.

Exhibit 10.33 Department of Health and Human Services National Institutes of Health NATIONAL INSTITUTE ON AGING Notice of Award FAIN# R01AG071643 Federal Award Date 05/06/2021 Recipient Information 1. Recipient Name COGNITION THERAPEUTICS, INC. 2403 SIDNEY ST STE 261 PITTSBURGH, PA 15203 2. Congressional District of Recipient 14 3. Payment System Identifier (ID) 1134365359A1 4. Employer Identifica

July 19, 2021 EX-10.25

Grant Agreement dated September 12, 2017 by and between the Registrant and the National Institute of Aging.

EX-10.25 24 tm2113659d7ex10-25.htm EXHIBIT 10.25 Exhibit 10.25 Notice of Award RESEARCH Department of Health and Human Services National Institutes of Health Federal Award Date: 09/12/2017 NATIONAL INSTITUTE ON AGING Grant Number: 1R01AG057553-01 FAIN: R01AG057553 Principal Investigator(s): SUSAN M CATALANO, PHD Project Title: A Pilot Synaptic Vesicle Glycoprotein 2A (SV2A) PET Study to Evaluate t

July 19, 2021 EX-10.14

Form of Stock Option Grant Notice and Award Agreement.

  Exhibit 10.14   COGNITION THERAPEUTICS, INC. 2021 EQUITY INCENTIVE PLAN   STOCK OPTION GRANT NOTICE AND AWARD AGREEMENT   Cognition Therapeutics, Inc., a Delaware corporation (the “Company”), pursuant to its 2021 Equity Incentive Plan (the “Plan”), hereby grants to the individual listed below (“Participant”) an option to purchase the number of Shares set forth below (the “Option”). The Option de

July 19, 2021 EX-10.3

First Amendment dated as of March 23, 2020, to the Third Amended and Restated Investor Rights Agreement dated as March 20, 2014, by and among the Registrant and the investors listed therein.

EX-10.3 9 tm2113659d7ex10-3.htm EXHIBIT 10.3 Exhibit 10.3 FIRST AMENDMENT TO THIRD AMENDED AND RESTATED INVESTORS’ RIGHTS AGREEMENT THIS FIRST AMENDMENT (the “First Amendment”) to that certain Third Amended and Restated Investors’ Rights Agreement dated as of March 20, 2014, among Cognition Therapeutics, Inc., a Delaware corporation (the “Company”) and its stockholders party thereto (the “Investor

July 19, 2021 S-1

Power of Attorney (included on the signature page to this registration statement).

S-1 1 tm2113659-6s1.htm S-1 TABLE OF CONTENTS As filed with the Securities and Exchange Commission on July 19, 2021. Registration No. 333-       UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM S-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 Cognition Therapeutics, Inc. (Exact name of registrant as specified in its charter) Delaware 2836 13-4365359 (State or

July 19, 2021 EX-10.19

Letter Agreement dated October 7, 2019, by and between the Registrant and James M. O’Brien.

Exhibit 10.19 Cognition Therapeutics Inc. 2403 Sidney Street Pittsburgh PA 15203 t: 412 481 2210 f: 412 481 2216 www.cogrx com October 7, 2019 Mr. James O?Brien 20 Hollow Tree Ridge Road Darien, Connecticut 06820 Dear Jim: This letter agreement (the ?Agreement?) sets forth the terms and conditions of your employment with Cognition Therapeutics, Inc., a Delaware corporation (the ?Company?). 1. Posi

July 19, 2021 EX-10.29

Grant Agreement dated September 5, 2020 by and between the Registrant and the National Institute of Aging.

Exhibit 10.29 Notice of Award Multi-Year Funded Research Project Grant Federal Award Date: 09/05/2020 Department of Health and Human Services National Institutes of Health NATIONAL INSTITUTE ON AGING Grant Number: 1RF1AG051593-01 FAIN: RF1AG051593 Principal Investigator(s): SUSAN M CATALANO, PHD Project Title: Phase 1 safety trial for CT1812, a novel small molecule therapeutic targeting a synaptic

July 19, 2021 EX-10.32

Grant Agreement dated April 30, 2021 by and between the Registrant and the National Institute of Aging.

EX-10.32 31 tm2113659d7ex10-32.htm EXHIBIT 10.32 Exhibit 10.32 Department of Health and Human Services National Institutes of Health NATIONAL INSTITUTE ON AGING Notice of Award FAIN# SB1AG073028 Federal Award Date 04/30/2021 Recipient Information Federal Award Information 1. Recipient Name COGNITION THERAPEUTICS, INC. 2403 SIDNEY ST STE 261 11. Award Number 1SB1AG073028-01A1 PITTSBURGH, PA 15203 1

July 19, 2021 EX-10.34

Grant Agreement dated May 10, 2021 by and between the Registrant and the National Institute of Aging

Exhibit 10.34 Department of Health and Human Services National Institutes of Health NATIONAL INSTITUTE ON AGING Notice of Award FAIN# R01AG058660 Federal Award Date 05/10/2021 Recipient Information 1. Recipient Name COGNITION THERAPEUTICS, INC. 2403 SIDNEY ST STE 261 PITTSBURGH, PA 15203 2. Congressional District of Recipient 14 3. Payment System Identifier (ID) 1134365359A1 4. Employer Identifica

July 19, 2021 EX-10.10

Second Amendment to 2017 Equity Incentive Plan.

Exhibit 10.10 AMENDMENT TO THE COGNITION THERAPEUTICS, INC. 2017 EQUITY INCENTIVE PLAN WHEREAS, Cognition Therapeutics, Inc. (the “Company”) has adopted the Cognition Therapeutics, Inc. 2017 Equity Incentive Plan (the “Plan”); WHEREAS, Section 12(a) of the Plan permits the Board of Directors of the Company (the “Board”) to amend the Plan from time to time; WHEREAS, pursuant to Section 3 of the Pla

July 19, 2021 EX-10.15

Employment Agreement dated June 1, 2020 by and between the Registrant and Lisa Ricciardi.

Exhibit 10.15 Execution Version EMPLOYMENT AGREEMENT EMPLOYMENT AGREEMENT effective as of June 1, 2020 (this “Agreement”) between Cognition Therapeutics, Inc. (the “Company”), a Delaware corporation, and Lisa Ricciardi (the “Executive”). Background: Executive and the Company entered into an employment agreement dated March 30, 2020 (the “Interim CEO Contract”) for Executive to serve as Interim Chi

July 19, 2021 EX-10.18

Advisor Services Agreement dated March 17, 2020 by and between the Registrant and Kenneth Moch.

Exhibit 10.18 ADVISOR SERVICES AGREEMENT This Advisor Services Agreement (“Agreement”), effective as of March 17, 2020, is made between Cognition Therapeutics, Inc. (the “Company”) and Kenneth I. Moch (“Advisor”). WHEREAS, Advisor’s employment by the Company ceased on March 17, 2020 (the “Termination Date”) and in connection therewith the Company and Advisor entered into a Separation and Release A

July 19, 2021 EX-3.4

Third Amendment to Second Amended and Restated Certificate of Incorporation, as filed with the Delaware Secretary of State on dated July 29, 2020.

Exhibit 3.4 THIRD CERTIFICATE OF AMENDMENT OF SECOND AMENDED AND RESTATED CERTIFICATE OF INCORPORATION OF COGNITION THERAPEUTICS, INC. Cognition Therapeutics, Inc. (the “Corporation”), a corporation organized and existing under and by virtue of the General Corporation Law of the State of Delaware, as the same may be amended from time to time (“DGCL”), DOES HEREBY CERTIFY THAT: FIRST: That the Boar

July 19, 2021 CORRESP

1

CORRESP 1 filename1.htm Troutman Pepper Hamilton Sanders LLP 3000 Two Logan Square, Eighteenth and Arch Streets Philadelphia, PA 19103-2799 troutman.com July 19, 2021 VIA EDGAR AND OVERNIGHT MAIL U.S. Securities and Exchange Commission 100 F. Street, N.E. Washington, D.C. 20549 Attention: Eric Atallah, Kevin Kuhar, Margaret Schwartz and Celeste Murphy Re: Cognition Therapeutics, Inc. Registration

July 19, 2021 EX-3.2

Amendment to Second Amended and Restated Certificate of Incorporation, as filed with the Delaware Secretary of State on dated January 10, 2017.

EX-3.2 3 tm2113659d7ex3-2.htm EXHIBIT 3.2 Exhibit 3.2 CERTIFICATE OF AMENDMENT OF SECOND AMENDED AND RESTATED CERTIFICATE OF INCORPORATION OF COGNITION THERAPEUTICS, INC. Cognition Therapeutics, Inc., a corporation organized and existing under and by virtue of the General Corporation Law of the State of Delaware (the “DGCL”), DOES HEREBY CERTIFY THAT: FIRST: The Board of Directors (the “Board”) of

July 19, 2021 EX-10.6

Office Lease dated July 1, 2021, by and between the Registrant and 2500/2700 Westchester Avenue Owner SPE LLC.

Exhibit 10.6 LEASE AGREEMENT BETWEEN 2500/2700 WESTCHESTER AVENUE OWNER SPE LLC, a Delaware Limited Liability Company, LANDLORD, -AND- COGNITION THERAPEUTICS, INC., a Delaware Corporation, TENANT Dated July 1, 2021 Prepared by: Robert A. Klausner, Esq. Fox Rothschild LLP 49 Market Street Morristown, New Jersey 07960 TABLE OF CONTENTS ARTICLE 1 DEFINITIONS 5 ARTICLE 2 DEMISE, TERM 5 ARTICLE 3 BASIC

July 19, 2021 EX-10.8

2017 Equity Incentive Plan.

EX-10.8 14 tm2113659d7ex10-8.htm EXHIBIT 10.8 Exhibit 10.8 Effective Date: September 20, 2017 COGNITION THERAPEUTICS, INC. 2017 EQUITY INCENTIVE PLAN The purpose of the Cognition Therapeutics, Inc. 2017 Equity Incentive Plan (this “Plan”) is to provide (i) designated employees of Cognition Therapeutics, Inc. (the “Company”) and its parents and subsidiaries, (ii) certain consultants and advisors wh

July 19, 2021 EX-10.17

Separation and Release Agreement dated April 21, 2020 by and between the Registrant and Kenneth Moch.

Exhibit 10.17 SEPARATION AND RELEASE AGREEMENT THIS SEPARATION AND RELEASE AGREEMENT (this “Agreement”) is made by and between Kenneth I. Moch (the “Executive”) and Cognition Therapeutics, Inc. (the “Company”). WHEREAS, the Company and the Executive entered into an Employment Agreement, effective October 11, 2016 and subsequently amended (the “Employment Agreement”), which governs the Executive’s

July 19, 2021 EX-10.2

Third Amended and Restated Investor Rights Agreement dated as of March 20, 2014, by and among the Registrant and the investors listed therein.

Exhibit 10.2 Execution Copy COGNITION THERAPEUTICS, INC. THIRD AMENDED AND RESTATED INVESTORS? RIGHTS AGREEMENT March 20, 2014 TABLE OF CONTENTS (continued) TABLE OF CONTENTS Page 1. Definitions 1 2. Registration Rights 4 2.1. Demand Registration 4 2.2. Company Registration 6 2.3. Underwriting Requirements 6 2.4. Obligations of the Company 8 2.5. Furnish Information 9 2.6. Expenses of Registration

July 19, 2021 EX-10.26

Grant Agreement dated April 18, 2018 by and between the Registrant and the National Institute of Aging.

EX-10.26 25 tm2113659d7ex10-26.htm EXHIBIT 10.26 Exhibit 10.26 Notice of Award Multi-Year Funded Research Project Grant Department of Health and Human Services National Institutes of Health Federal Award Date: 04/18/2018 NATIONAL INSTITUTE ON AGING Grant Number: 1RF1AG057780-01 REVISED FAIN: RF1AG057780 Principal Investigator(s): SUSAN M CATALANO, PHD Project Title: A Pilot CSF Catheter Study to E

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